Works (79)

2017 journal article

Vitreous humor changes expression of iron-handling proteins in lens epithelial cells

Investigative Ophthalmology and Visual Science, 58(2).

By: M. Goralska, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Evaluation of the proliferative capacity of canine retinal pigment epithelial cells harvested from different regions of the fundus

Investigative Ophthalmology and Visual Science, 57(12).

By: F. Mowat, J. Hash, P. Mzyk, J. Harned, S. Nagar & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Hypoxia alters the expression, movement, and secretion of APP in retinal pigmented epithelial (RPE) cells

Investigative Ophthalmology and Visual Science, 57(12).

By: P. Mzyk & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Hypoxia controls iron metabolism and glutamate secretion in retinal pigmented epithelial cells

Biochimica Et Biophysica Acta. G, General Subjects, 1840(10), 3138–3144.

By: J. Harned, S. Nagar & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Hypoxia induced changes in expression of proteins involved in iron uptake and storage in cultured lens epithelial cells

Experimental Eye Research, 125, 135–141.

By: M. Goralska, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells

Molecular Vision, 19, 2106–2112.

By: M. Lall, J. Harned & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Ceruloplasmin alters intracellular iron regulated proteins and pathways: Ferritin, transferrin receptor, glutamate and hypoxia-inducible factor-1α

Experimental Eye Research, 97(1), 90–97.

By: J. Harned, J. Ferrell, S. Nagar, M. Goralska, L. Fleisher & M. McGahan

Source: Crossref
Added: July 20, 2019

2010 journal article

Altered ferritin subunit composition: Change in iron metabolism in lens epithelial cells and downstream effects on glutathione levels and VEGF secretion

Investigative Ophthalmology and Visual Science, 51(9), 4437–4446.

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Changes in ferritin H- and L-chains in canine lenses with age-related nuclear cataract

Investigative Ophthalmology and Visual Science, 50(1), 305–310.

By: M. Goralska, S. Nagar, C. Colitz, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Distribution of ferritin chains in canine lenses with and without age-related nuclear cataracts

Molecular Vision, 15(256-59), 2404–2410.

By: M. Goralska, S. Nagar, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Iron metabolism in the eye: A review

Experimental Eye Research, 88(2), 204–215.

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase

Investigative Ophthalmology and Visual Science, 49(1), 310–319.

By: M. Lall, J. Ferrell, S. Nagar, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Ferritin H- and L-chains in fiber cell canine and human lenses of different ages

Investigative Ophthalmology and Visual Science, 48(9), 3968–3975.

By: M. Goralska, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Lens epithelial cells synthesize and secrete ceruloplasmin: Effects of ceruloplasmin and transferrin on iron efflux and intracellular iron dynamics

Experimental Eye Research, 83(4), 721–727.

By: J. Harned, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Differential degradation of ferritin H- and L-chains: Accumulation of L-chain-rich ferritin in lens epithelial cells

Investigative Ophthalmology and Visual Science, 46(10), 3521–3529.

By: M. Goralska, S. Nagar, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Iron alters glutamate secretion by regulating cytosolic aconitase activity

American Journal of Physiology. Cell Physiology, 288(5), C1117–1124.

By: M. McGahan, J. Harned, M. Mukunnemkeril, M. Goralska, L. Fleisher & J. Ferrell

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Alpha lipoic acid changes iron uptake and storage in lens epithelial cells

Experimental Eye Research, 76(2), 241–248.

By: M. Goralska, R. Dackor, B. Holley & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Identification of a mechanism by which lens epithelial cells limit accumulation of overexpressed ferritin H-chain

Journal of Biological Chemistry, 278(44), 42920–42926.

By: M. Goralska, B. Holley & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

The effect of UVB irradiation on ferritin subunit synthesis, ferritin assembly and Fe metabolism in cultured canine lens epithelial cells

Photochemistry and Photobiology, 77(4), 440–445.

By: J. Harned, A. Grimes & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

The effect of UVB irradiation on ferritin subunit synthesis, ferritin assembly and Fe metabolism in cultured canine lens epithelial cells

The Journal of Biological Chemistry, 278, 42920–42926.

By: M. Goralska, B. Holley & M. McGahan

Source: NC State University Libraries
Added: September 9, 2019

2001 journal article

Overexpression of H- and L-ferritin subunits in lens epithelial cells: Fe metabolism and cellular response to UVB irradiation

Investigative Ophthalmology and Visual Science, 42(8), 1721–1727.

By: M. Goralska, B. Holley & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Effect of surgical technique on in vitro posterior capsule opacification

Journal of Cataract and Refractive Surgery, 26(10), 1550–1554.

By: M. Davidson, D. Morgan & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Ex vivo canine lens capsular sac explants

Graefes Archive for Clinical and Experimental Ophthalmology, 238(8), 708–714.

By: M. Davidson, M. Wormstone, D. Morgan, R. Malakof, J. Allen & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Histologic and immunohistochemical characterization of lens capsular plaques in dogs with cataracts

American Journal of Veterinary Research, 61(2), 139–143.

By: C. Colitz, D. Malarkey, M. Dykstra, M. McGahan & M. Davidson

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Rabbit pigmented ciliary epithelium produces interleukin-6 in response to inflammatory cytokines

Experimental Eye Research, 70(3), 271–279.

By: L. Fleisher, M. McGahan & J. Ferrell

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

The effects of Tempol on ferritin synthesis and Fe metabolism in lens epithelial cells

Biochimica Et Biophysica Acta, 1497(1), 51–60.

By: M. Goralska, B. Holley & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Telomerase activity in lens epithelial cells of normal and cataractous lenses

Experimental Eye Research, 69(6), 641–649.

By: C. Colitz, M. Davidson & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Characterization of canine MDR1 mRNA: Its abundance in drug resistant cell lines and in vivo

Anticancer Research, 18(1A), 393–400.

By: S. Steingold, N. Sharp, M. McGahan, C. Hughes, S. Dunn & R. Page

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

The effect of ascorbic acid and ferric ammonium citrate on iron uptake and storage in lens epithelial cells

Experimental Eye Research, 66(6), 687–697.

By: M. Goralska, J. Harned, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

The lens influences aqueous humor levels of transforming growth factor-beta 2

Graefes Archive for Clinical and Experimental Ophthalmology, 236(4), 305–311.

By: J. Allen, M. Davidson, M. Nasisse, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Transferrin in after-cataract and as a survival factor for lens epithelium

Experimental Eye Research, 66(2), 207–215.

By: M. Davidson, J. Harned, A. Grimes, G. Duncan, I. Wormstone & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Mechanisms by which ascorbic acid increases ferritin levels in cultured lens epithelial cells

Experimental Eye Research, 64(3), 413–421.

Source: NC State University Libraries
Added: August 6, 2018

1997 chapter

Nitric oxide in ocular inflammation

In Advances in ocular toxicology (pp. 121–131).

By: J. Allen, M. McGahan, L. Fleisher, G. Jaffe & C. Privalle

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Hemoglobin exacerbates the ocular inflammatory response to endotoxin

Graefes Archive for Clinical and Experimental Ophthalmology, 234, 643–647.

By: M. McGahan, A. Grimes & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Inhibition of lipopolysaccharide-induced uveitis by nitric oxide synthase inhibitors.

Experimental Eye Research, 62, 21–28.

By: J. Allen, M. McGahan, K. Adler, J. Ferrell & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Interleukin-1[beta] increases prostaglandin E2 stimulated adenosine 3',5'-cyclic monophosphate production in rabbit pigmented ciliary epithelium

Experimental Eye Research, 63, 91–104.

By: L. Fleisher, M. McGahan, J. Ferrell & I. Pagan

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Intravitreal transforming growth factor-[beta]2 decreases cellular infiltration in endotoxin-induced ocular inflammation in rabbits

Current Eye Research, 15, 95–103.

By: J. Allen, M. McGahan, Y. Ogawa, D. Sellon, B. Clark & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Inflammation induced changes in adenosine 3',5'-cyclic monophosphate production by ciliary epithelial cell bilayers.

Experimental Eye Research, 60, 165–171.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Iron uptake in cultured lens epithelial cells

Graefes Archive for Clinical and Experimental Ophthalmology, 233, 354–359.

By: M. McGahan, A. Grimes, M. Nasisse & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Mediators of the ocular inflammatory response to IL-1[beta] plus TNFI?

Graefes Archive for Clinical and Experimental Ophthalmology, 233, 94–100.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Transferrin secretion by lens epithelial cells in culture

Experimental Eye Research, 60, 667–673.

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

Influence of exposure time on the inflammatory response to continuous wave neodymium:YAG laser cyclophotocoagulation in rabbits

Archives of Ophthalmology, 112, 977–981.

By: D. Echelman, M. Nasisse, M. Shields, M. McGahan & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

Regulation of ferritin levels in cultured lens epithelial cells

Experimental Eye Research, 59, 551–556.

By: M. McGahan, J. Harned, A. Grimes & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

Transferrin inhibits the ocular inflammatory response

Experimental Eye Research, 58, 509–511.

By: M. McGahan, A. Grimes & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Cellular response to intravitreal injection of endotoxin and xanthine oxidase in rabbits

Graefes Archive for Clinical and Experimental Ophthalmology, 230, 463–467.

By: M. McGahan & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Does the lens serve as a sink for iron during ocular inflammation?

Experimental Eye Research, 54, 525–530.

By: M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Effects of copper loading and depletion on rabbit superoxide dismutase activity

Trace Elements in Medicine, 9, 55–58.

By: J. Ferrell, L. Fleisher, M. Smith & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Synergistic uveitic effects of tumor necrosis factor-alpha and interleukin-1 beta

Investigative Ophthalmology and Visual Science, 33, 2120–2127.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

Effects of copper depletion and d-penicillamine treatment on the ocular inflammatory response

Agents & Actions, 34, 405–409.

By: M. McGahan, L. Fleisher & A. Grimes

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

Lipid mediators of TNF- induced uveitis

Investigative Ophthalmology and Visual Science, 32, 2393–2399.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

Selenium concentration in ocular tissues and fluids

Ophthalmic Research, 23, 45–50.

By: M. McGahan & A. Grimes

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Copper and aspirin treatment increase the antioxidant activity of plasma

Agents & Actions, 31, 59–64.

By: M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Ocular inflammatory effects of intravitreally injected tumor necrosis factor-alpha and endotoxin

Inflammation, 14, 325–335.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1989 journal article

Clinical signs of the acute ocular inflammatory response to endotoxin are not altered by increasing the antioxidant potency of the intraocular fluids

Inflammation, 13, 393–400.

By: M. McGahan, L. Fleisher & A. Grimes

Source: NC State University Libraries
Added: August 6, 2018

1989 journal article

Dimethylthiourea inhibits the inflammatory response to intravitreally injected endotoxin

Experimental Eye Research, 48, 561–567.

By: L. Fleisher, J. Ferrell, N. Olson & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1989 journal article

Ferroxidase activity increases dramatically in the aqueous humor during the ocular inflammatory response

Ophthalmic Research, 21, 221–225.

By: M. McGahan, A. Grimes & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

Inflammation-induced changes in the concentration of iron and total-iron-binding capacity in the intraocular fluids of rabbits

Graefes Archive for Clinical and Experimental Ophthalmology, 226, 27–30.

By: M. McGahan & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1987 journal article

Cysteine - an effective matrix modifier for the determination of gold in biological samples by electrothermal atomic absorption spectroscopy

Spectrochimica Acta. Part B, Atomic Spectroscopy, 42, 909–913.

By: D. Matthews & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1987 journal article

The determination of platinum in biological materials by electrothermal atomic absorption spectroscopy

Spectrochimica Acta. Part B, Atomic Spectroscopy, 42, 665–668.

By: M. McGahan & K. Tyczkowska

Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

A micromethod for the determination of iron and total-iron-binding capacity in intraocular fluids and plasma using electrothermal atomic absorption spectroscopy

Analytical Biochemistry, 156, 397–402.

By: M. McGahan & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

Antioxidant activity of aqueous and vitreous humor from the inflamed rabbit eye

Current Eye Research, 5, 641–645.

By: M. McGahan & L. Fleisher

Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

Copper concentration in cornea, iris, normal and cataractous lenses, and intraocular fluids of vertebrates

Current Eye Research, 5, 69–76.

By: C. Cook & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

Effects of melittin on a model renal epithelium, the toad urinary bladder

Biochimica Et Biophysica Acta, 855, 63–67.

By: M. McGahan, D. Matthews & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

The pathophysiology of the ocular microenvironment. II. Copper-induced ocular inflammation and hypotony

Experimental Eye Research, 42, 595–605.

By: M. McGahan, L. Bito & B. Meyers

Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

Time course for prostaglandin synthesis by rabbit lens during endotoxin-induced ocular inflammation

Current Eye Research, 5, 629–634.

By: L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1985 journal article

Ascorbic acid levels in the aqueous and vitreous humor of rabbits: Effects of inflammation and ceruloplasmin

Experimental Eye Research, 41, 291–298.

By: M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1985 journal article

Endotoxin-induced inflammation stimulates prostaglandin production by the rabbit lens

Experimental Eye Research, 40, 711–719.

By: L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1985 journal article

Melittin-induced changes in Na and Cl movements across toad's skin and cornea (in vitro) of the toad, Bufo marinus

Comparative Biochemistry and Physiology, 291–296.

By: M. McGahan, R. Hazard & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018

1983 journal article

Calcium metabolism of the rabbit lens

Experimental Eye Research, 36, 57–66.

By: M. McGahan, B. Chin & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018

1983 journal article

Determination of copper concentration in blood plasma and in ocular and cerebrospinal fluids using graphite furnace atomic absorption spectroscopy.

Analytical Biochemistry, 135, 186–192.

By: M. McGahan & L. Bito

Source: NC State University Libraries
Added: August 6, 2018

1983 journal article

Some observations on the magnesium metabolism of the rabbit lens

Experimental Eye Research, 36, 67–73.

By: M. McGahan, B. Chin & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018

1983 journal article

The pathophysiology of the ocular micro-environment. I. Preliminary report on the possible involvement of copper in ocular inflammation

Current Eye Research, 2, 883–885.

By: M. McGahan & L. Bito

Source: NC State University Libraries
Added: August 6, 2018

1982 journal article

A pharmacological analysis of chloride transport across the amphibian cornea

Journal of Physiology (London), 325, 481–492.

By: P. Bentley & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1982 journal article

Stimulation of transepithelial Na and Cl transport by ascorbic acid. Induction of Na channels is inhibited by amiloride

Biochimica Et Biophysica Acta, 689, 385–392.

By: M. McGahan & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018

1981 journal article

Alpha-aminoisobutyric acid efflux from the cornea of the toad, Bufo marinus

Journal of Physiology (London), 315, 253–266.

By: M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1981 journal article

Alpha-aminoisobutyric acid transport in the amphibian crystalline lens

Journal of Physiology (London), 34, 49–56.

By: M. McGahan & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018

1981 journal article

Inhibition of alpha-aminoisobutyric acid uptake by diisothiocyano stilbene disulphonic acid in the amphibian cornea

Biochimica Et Biophysica Acta, 643, 261–264.

By: M. McGahan & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018

1980 journal article

Inhibitory effects of DIDS on Cl transport across the cornea

Journal of Physiology (London), 304, 519–527.

By: P. Bentley & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1977 journal article

The mode of action of bumetanide: inhibition of chloride transport across the amphibian cornea

Journal of Pharmacology and Experimental Therapeutics, 203, 97–102.

By: M. McGahan, T. Yorio & P. Bentley

Source: NC State University Libraries
Added: August 6, 2018