@article{whitehead_petritz_doerr_stoskopf_harrison_2020, title={Biochemical Effects of Routine Gonadectomy on Blood of Domestic Ferrets (Mustela putorius furo)}, volume={59}, ISSN={["1559-6109"]}, DOI={10.30802/AALAS-JAALAS-19-000173}, abstractNote={We studied domestic ferrets (Mustela putorius furo) to evaluate the physiologic effects of routine surgery. Standard plasma biochemistry panels and 1H-NMR spectroscopy of heparinized whole blood were performed on samples taken 24 h prior to and immediately after surgery
 from female and male ferrets undergoing routine gonadectomy. Increases in plasma glucose, phosphorus, potassium, and creatine kinase concentrations associated with the duration of surgery were identified on plasma biochemistry panels. Whole-blood NMR spectra allowed us to identify 42 metabolites
 and one drug residue. Variations between pre- and postoperative metabolite concentrations were most pronounced for female ferrets, which underwent more prolonged surgery than males. Affected metabolites included organic acids and osmolytes (betaine, methylmalonate, <small>D</small>-lactate),
 fatty acids and lipids (2-hydroxy-3-methylbutyric acid), and amino acid groups (acetylglycine, alloisoleucine, leucine, and isoleucine). These findings indicate that 1H-NMR spectroscopy of whole blood provides insight into metabolic perturbations in domestic ferrets undergoing surgery
 that are not detected in routine clinical chemistry panels.}, number={5}, journal={JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE}, author={Whitehead, Michelle C. and Petritz, Olivia A. and Doerr, Mary and Stoskopf, Michael K. and Harrison, Tara M.}, year={2020}, month={Sep}, pages={567–574} }
 @article{petritz_westermeyer_whitehead_christiansen_lohmann_lohmann_lewbart_2020, title={Effective mydriasis in juvenile loggerhead turtles (Caretta caretta) following topical administration of rocuronium bromide and 10% phenylephrine}, volume={23}, ISSN={["1463-5224"]}, DOI={10.1111/vop.12681}, abstractNote={Abstract}, number={1}, journal={VETERINARY OPHTHALMOLOGY}, author={Petritz, Olivia A. and Westermeyer, Hans D. and Whitehead, Michelle C. and Christiansen, Emily F. and Lohmann, Kenneth J. and Lohmann, Catherine M. F. and Lewbart, Gregory A.}, year={2020}, month={Jan}, pages={37–43} }
 @article{whitehead_vanetten_zheng_lewbart_2019, title={Hematological parameters in largemouth bass (Micropterus salmoides) with formalin-preservation: comparison between wild tournament-caught and captive-raised fish}, volume={7}, ISSN={["2167-8359"]}, DOI={10.7717/peerj.6669}, abstractNote={BackgroundLargemouth bass (Micropterus salmoides) are an economically important freshwater fish species that have been investigated for both the short and long-term effects of stress, secondary to angling. Limited data has been published on the hematological parameters of this species and blood sample stability is a notable limitation of hematologic field studies. A relatively novel technique using 10% neutral buffered formalin preserves heparinized whole blood and maintains blood cell stability beyond one month in striped bass. The objective of this study was to evaluate the differences in hematological parameters between tournament-caught and captive-raised largemouth bass using whole blood preservation with neutral buffered formalin.}, journal={PEERJ}, author={Whitehead, Michelle C. and Vanetten, Chelsey L. and Zheng, Yaxin and Lewbart, Gregory A.}, year={2019}, month={Apr} }
 @article{whitehead_hoppes_musser_perkins_lepiz_2019, title={The Use of Alfaxalone in Quaker Parrots (Myiopsitta monachus)}, volume={33}, ISSN={["1938-2871"]}, DOI={10.1647/2018-393}, abstractNote={Abstract: Alfaxalone is a neurosteroid anesthetic that acts on gamma-aminobutyric acid alpha-receptors. The objective of this study was to evaluate the clinical safety and efficacy of alfaxalone (Alfaxan CD). Due to observed hyperexcitability in the subject animals when alfaxalone was the only drug used during the initial trials, premedication with midazolam was also evaluated during the final study. Ten adult Quaker parrots (Myiopsitta monachus) were assigned to 3 groups: 1) low-dose alfaxalone 10 mg/kg (LD), 2) high-dose alfaxalone 25 mg/kg (HD), and 3) alfaxalone 10 mg/ kg with midazolam 1 mg/kg premedication (AM), administered intramuscularly. Induction time, sedation quality, duration of action, and vital parameters, including heart rate, respiratory rate, and temperature, were recorded. All protocols achieved adequate sedation; however, muscle tremors and hyperexcitation were variable. The LD group had a significantly longer mean ± SD induction time (13.5 ± 4.5 minutes) as compared to the HD (6.0 ± 1.3 minutes, P = .002) and AM (6.5 ± 2.9 minutes, P = .006) groups, while recovery time was significantly longer in the HD group (86.2 ± 13.4 minutes) than the LD group (44.4 ± 10.8 minutes, P < .001). Midazolam premedication resulted in reduction of both muscle tremors and hyperexcitation associated with alfaxalone administration, but the recovery time was significantly longer (103.5 ± 15.1 minutes, P < .001) than for the LD group. Alfaxalone as a sole agent resulted in muscle tremors and hyperexcitation during induction, which was attenuated by premedication with midazolam. Further investigation is warranted to characterize the effects of alfaxalone and drugs used to premedicate Quaker parrots.}, number={4}, journal={JOURNAL OF AVIAN MEDICINE AND SURGERY}, author={Whitehead, Michelle C. and Hoppes, Sharman M. and Musser, Jeffrey M. B. and Perkins, Jennifer L. and Lepiz, Mauricio L.}, year={2019}, month={Dec}, pages={340–348} }
 @article{whitehead_vanetten_jacob_harrison_2018, title={Microbial integrity of preservative-free alfaxalone in a multiple-use system for two storage conditions and three handling techniques}, volume={79}, ISSN={["1943-5681"]}, DOI={10.2460/ajvr.79.7.704}, abstractNote={Abstract}, number={7}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Whitehead, Michelle C. and Vanetten, Chelsey L. and Jacob, Megan E. and Harrison, Tara M.}, year={2018}, month={Jul}, pages={704–710} }