Matthew Douglas Moore

Works (15)

Updated: July 24th, 2023 21:16

2022 article

Efficacy and Mechanisms of Copper Ion-Catalyzed Inactivation of Human Norovirus

Mertens, B. S., Moore, M. D., Jaykus, L.-A., & Velev, O. D. (2022, March 22). ACS Infectious Diseases, Vol. 4.

By: B. Mertens n, M. Moore n, L. Jaykus n & O. Velev n 

author keywords: norovirus; viral inactivation; antiviral; copper; Tulane virus; disinfection
MeSH headings : Alloys / pharmacology; Capsid Proteins; Catalysis; Copper / pharmacology; Ions; Norovirus / drug effects; Norovirus / physiology; Virus Inactivation
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Virus-based gene therapy research; Viral Infections and Immunology Research
TL;DR: The combined data demonstrate that stabilized Cu(I) ion solutions show promise as highly effective noroviral disinfectants in solution that can potentially be utilized at low concentrations for inactivation of human noroviruses. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022

2021 article

Comparison of a one-step real-time RT-PCR and a nested real-time RT-PCR for a genogroup II norovirus reveals differences in sensitivity depending upon assay design and visualization

Manuel, C. S., Suther, C., Moore, M. D., & Jaykus, L.-A. (2021, April 8). PLoS ONE.

By: C. Manuel n, C. Suther *, M. Moore n & L. Jaykus n

MeSH headings : Caliciviridae Infections / diagnosis; Caliciviridae Infections / genetics; Caliciviridae Infections / metabolism; Feces / virology; Female; Genome, Viral; Humans; Male; Norovirus / genetics; RNA, Viral / genetics; RNA, Viral / metabolism; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Virus-based gene therapy research; Animal Virus Infections Studies
TL;DR: A controlled comparison of two published NoV detection assays shows the complexities in designing and interpreting molecular techniques having a sufficient detection limit to detect low levels of viruses that might be anticipated in contaminated food and environmental samples. (via Semantic Scholar)
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Source: Web Of Science
Added: June 10, 2021

2021 article

Generation of Nucleic Acid Aptamer Candidates against a Novel Calicivirus Protein Target

Faircloth, J., Moore, M. D., Stoufer, S., Kim, M., & Jaykus, L.-A. (2021, August 29). Viruses.

By: J. Faircloth n, M. Moore n, S. Stoufer *, M. Kim * & L. Jaykus n

author keywords: norovirus; aptamer; VPg; detection; Norwalk virus; Tulane virus; infectivity; therapeutics
MeSH headings : Aptamers, Nucleotide / genetics; Caliciviridae / genetics; DNA, Single-Stranded / genetics; DNA, Single-Stranded / metabolism; Genome, Viral; Humans; Nucleic Acids / genetics; Nucleic Acids / metabolism; SELEX Aptamer Technique / methods; Viral Proteins / genetics; Viral Proteins / metabolism
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Animal Virus Infections Studies
TL;DR: A number of aptamer candidates found to be broadly reactive and specific for in vitro-expressed VPgs across genus that could be used for future application in detection or therapeutics are reported. (via Semantic Scholar)
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Source: Web Of Science
Added: October 12, 2021

2017 article

A plate-based histo-blood group antigen binding assay for evaluation of human norovirus receptor binding ability

Moore, M. D., & Jaykus, L.-A. (2017, June 27). Analytical Biochemistry.

By: M. Moore n & L. Jaykus n

author keywords: Norovirus; Disinfection; Capsid functionality; Histo-blood group antigens; Receptor binding assay
MeSH headings : Amino Acid Sequence / genetics; Blood Group Antigens / immunology; Blood Group Antigens / isolation & purification; Capsid Proteins / blood; Gastroenteritis / diagnosis; Gastroenteritis / virology; Genotype; Humans; Norovirus / genetics; Norovirus / immunology; Norovirus / isolation & purification; Norovirus / pathogenicity; Protein Binding
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Animal Virus Infections Studies
TL;DR: A streamlined version of a receptor-binding assay with minimal time-to-result while maintaining accuracy and high throughput is presented, validating assay performance for physical and chemical inactivation treatments of a norovirus GII. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 article

Development of a Recombinase Polymerase Amplification Assay for Detection of Epidemic Human Noroviruses

Moore, M. D., & Jaykus, L.-A. (2017, January 9). Scientific Reports.

By: M. Moore n & L. Jaykus n

MeSH headings : Caliciviridae Infections / diagnosis; Caliciviridae Infections / genetics; Epidemics / prevention & control; Humans; Norovirus / genetics; Norovirus / isolation & purification; Real-Time Polymerase Chain Reaction / methods; Recombinases / analysis; Recombinases / genetics; Reverse Transcriptase Polymerase Chain Reaction / methods
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Virus-based gene therapy research; Animal Virus Infections Studies
TL;DR: The reported RT-RPA method shows promise for sensitive point-of-care detection of epidemic human norovirus detection, and is the fastest human Norovirus amplification method to date. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 article

Human norovirus binding to select bacteria representative of the human gut microbiota

Almand, E. A., Moore, M. D., Outlaw, J., & Jaykus, L.-A. (2017, March 3). PLoS ONE.

By: E. Almand  n, M. Moore n, J. Outlaw n & L. Jaykus n

MeSH headings : Bacillus / isolation & purification; Bacillus / metabolism; Citrobacter / isolation & purification; Citrobacter / metabolism; Culture Media / chemistry; Enterobacter cloacae / isolation & purification; Enterobacter cloacae / metabolism; Enterococcus faecium / isolation & purification; Enterococcus faecium / metabolism; Feces / microbiology; Fimbriae, Bacterial / chemistry; Fimbriae, Bacterial / metabolism; Fimbriae, Bacterial / ultrastructure; Gastrointestinal Microbiome / physiology; Hafnia alvei / isolation & purification; Hafnia alvei / metabolism; Humans; Klebsiella / isolation & purification; Klebsiella / metabolism; Microbial Interactions; Norovirus / metabolism; Norovirus / ultrastructure; Staphylococcus aureus / isolation & purification; Staphylococcus aureus / metabolism
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Clostridium difficile and Clostridium perfringens research; Virus-based gene therapy research
TL;DR: The findings reported here further elucidate and inform the dynamics between human noroviruses and enteric bacteria with implications for norovirus pathogenesis. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2017 article

Norovirus Binding to Ligands Beyond Histo-Blood Group Antigens

Almand, E. A., Moore, M. D., & Jaykus, L.-A. (2017, December 21). Frontiers in Microbiology.

By: E. Almand  n, M. Moore n & L. Jaykus n

author keywords: norovirus; histo-blood group antigens; virus-bacteria interaction; transkingdom; enteric virus
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Advanced Thermodynamic Systems and Engines; Virus-based gene therapy research
TL;DR: This review seeks to supplement the already well-covered HBGA-norovirus literature by covering non-HBGA human norovirus ligands and inhibitors to provide investigators with a more comprehensive view of norov virus ligands. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2017 article

Recombinase Polymerase Amplification: A Promising point-of-care Detection Method for Enteric Viruses

Moore, M. D., & Jaykus, L.-A. (2017, June 21). Future Virology.

By: M. Moore n & L. Jaykus n

author keywords: detection; enteric virus; in-field; point-of-care; recombinase polymerase amplification
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Animal Virus Infections Studies; Viral Infections and Immunology Research
TL;DR: This report reviews the use of recombinase polymerase amplification for virus detection, showing that the method has favorable fundamental properties supporting its promise for rapid point-of-care detection of enteric viruses. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2017 review

Virus-bacteria interactions: An emerging topic in human infection

[Review of ]. Viruses-Basel, 9(3).

By: E. Almand, M. Moore & L. Jaykus

Source: NC State University Libraries
Added: August 6, 2018

2016 article

Efficacy of a disinfectant containing silver dihydrogen citrate against GI .6 and GII .4 human norovirus

Manuel, C. S., Moore, M. D., & Jaykus, L. A. (2016, October 24). Journal of Applied Microbiology.

By: C. Manuel n, M. Moore n & L. Jaykus n

author keywords: antimicrobials; disinfection; environmental; food safety; norovirus; viruses
MeSH headings : Capsid Proteins / genetics; Citrates / pharmacology; Disinfectants / pharmacology; Humans; Norovirus / drug effects; Norovirus / genetics; Real-Time Polymerase Chain Reaction; Silver Compounds / pharmacology
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Virus-based gene therapy research; Animal Virus Infections Studies
TL;DR: This study tested the efficacy of an antimicrobial product containing a blend of silver ions and citric acid (silver dihydrogen citrate; SDC) against GI. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2016 article

Human Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle Functionality

Moore, M. D., Bobay, B. G., Mertens, B., & Jaykus, L.-A. (2016, November 3). MSphere.

By: M. Moore n, B. Bobay n, B. Mertens n & L. Jaykus n

author keywords: aptamer; GII.4; histo-blood group antigen; infectivity; noroviruses
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Advanced Thermodynamic Systems and Engines
TL;DR: A hitherto unexplored property of a different type of ligand, a nucleic acid aptamer, to mimic receptor binding behavior and assess capsid functionality for a selected strain of norovirus is reported, suggesting that other aptamers may show promise in the study of other fastidious microorganisms. (via Semantic Scholar)
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10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 article

Destruction of the Capsid and Genome of GII.4 Human Norovirus Occurs during Exposure to Metal Alloys Containing Copper

Manuel, C. S., Moore, M. D., & Jaykus, L. A. (2015, May 16). Applied and Environmental Microbiology.

By: C. Manuel n, M. Moore n & L. Jaykus n

MeSH headings : Alloys / toxicity; Blotting, Western; Capsid / drug effects; Copper / toxicity; Feces / virology; Genome, Viral / drug effects; Humans; Microscopy, Electron, Transmission; Norovirus / drug effects; Norovirus / physiology; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Virus Attachment / drug effects
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Virus-based gene therapy research
TL;DR: It is suggested that copper surfaces destroy HuNoV and may be useful in preventing environmental transmission of the virus in at-risk settings. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 article

Generation and characterization of nucleic acid aptamers targeting the capsid P domain of a human norovirus GII.4 strain

Moore, M. D., Escudero-Abarca, B. I., Suh, S. H., & Jaykus, L.-A. (2015, June 14). Journal of Biotechnology.

By: M. Moore n, B. Escudero-Abarca n, S. Suh n & L. Jaykus n

author keywords: SELEX; Aptamer; Norovirus; Molecular detection; Viral diagnostics
MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Capsid Proteins / genetics; Capsid Proteins / metabolism; Feces / virology; Humans; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; SELEX Aptamer Technique / methods; Sensitivity and Specificity
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Virus-based gene therapy research
TL;DR: This is the first demonstration of human NoV P domain protein as a functional target for the selection of nucleic acid aptamers that specifically bind and broadly recognize diversehuman NoV strains. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 article

Human Norovirus as a Foodborne Pathogen: Challenges and Developments

Moore, M. D., Goulter, R. M., & Jaykus, L.-A. (2015, April 10). Annual Review of Food Science and Technology.

By: M. Moore n, R. Goulter n & L. Jaykus n

author keywords: epidemiology; detection; evolution; cell culture; infectivity
MeSH headings : Animals; Caliciviridae Infections / epidemiology; Caliciviridae Infections / virology; Cell Line; Food / virology; Gastroenteritis / epidemiology; Gastroenteritis / virology; Humans; Norovirus / classification; Norovirus / pathogenicity; Phylogeny
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Animal Virus Infections Studies
TL;DR: A brief overview of NoVs and their genetic structure is provided and the challenges and recent developments related to human NoVs regarding viral evolution, transmission, epidemiology, outbreak identification, cultivation, animal and human models, and detection are presented. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2014 article

Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains

Escudero-Abarca, B. I., Suh, S. H., Moore, M. D., Dwivedi, H. P., & Jaykus, L.-A. (2014, September 5). PLoS ONE.

By: B. Escudero-Abarca n, S. Suh n, M. Moore n, H. Dwivedi n & L. Jaykus n

MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Bacteriological Techniques / methods; DNA, Viral / chemistry; DNA, Viral / metabolism; Feces / virology; Food Microbiology; Humans; Lettuce / virology; Molecular Structure; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; Sensitivity and Specificity
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Animal Virus Infections Studies; Viral Infections and Immunology Research
TL;DR: These ssDNA aptamer candidates show promise as broadly reactive reagents for use in HuNoV capture and detection assays in various sample types. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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