Matthew Douglas Moore

Works (15)

Updated: July 24th, 2023 21:16

2022 journal article

Efficacy and Mechanisms of Copper Ion-Catalyzed Inactivation of Human Norovirus br

ACS INFECTIOUS DISEASES, 8(4), 855–864.

By: B. Mertens n, M. Moore n, L. Jaykus n & O. Velev n 

author keywords: norovirus; viral inactivation; antiviral; copper; Tulane virus; disinfection
MeSH headings : Alloys / pharmacology; Capsid Proteins; Catalysis; Copper / pharmacology; Ions; Norovirus / drug effects; Norovirus / physiology; Virus Inactivation
TL;DR: The combined data demonstrate that stabilized Cu(I) ion solutions show promise as highly effective noroviral disinfectants in solution that can potentially be utilized at low concentrations for inactivation of human noroviruses. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022

2021 journal article

Comparison of a one-step real-time RT-PCR and a nested real-time RT-PCR for a genogroup II norovirus reveals differences in sensitivity depending upon assay design and visualization

PLOS ONE, 16(4).

By: C. Manuel n, C. Suther *, M. Moore n & L. Jaykus n

MeSH headings : Caliciviridae Infections / diagnosis; Caliciviridae Infections / genetics; Caliciviridae Infections / metabolism; Feces / virology; Female; Genome, Viral; Humans; Male; Norovirus / genetics; RNA, Viral / genetics; RNA, Viral / metabolism; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction
TL;DR: A controlled comparison of two published NoV detection assays shows the complexities in designing and interpreting molecular techniques having a sufficient detection limit to detect low levels of viruses that might be anticipated in contaminated food and environmental samples. (via Semantic Scholar)
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Source: Web Of Science
Added: June 10, 2021

2021 journal article

Generation of Nucleic Acid Aptamer Candidates against a Novel Calicivirus Protein Target

VIRUSES-BASEL, 13(9).

By: J. Faircloth n, M. Moore n, S. Stoufer *, M. Kim * & L. Jaykus n

author keywords: norovirus; aptamer; VPg; detection; Norwalk virus; Tulane virus; infectivity; therapeutics
MeSH headings : Aptamers, Nucleotide / genetics; Caliciviridae / genetics; DNA, Single-Stranded / genetics; DNA, Single-Stranded / metabolism; Genome, Viral; Humans; Nucleic Acids / genetics; Nucleic Acids / metabolism; SELEX Aptamer Technique / methods; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR: A number of aptamer candidates found to be broadly reactive and specific for in vitro-expressed VPgs across genus that could be used for future application in detection or therapeutics are reported. (via Semantic Scholar)
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Source: Web Of Science
Added: October 12, 2021

2017 journal article

A plate-based histo-blood group antigen binding assay for evaluation of human norovirus receptor binding ability

ANALYTICAL BIOCHEMISTRY, 533, 56–59.

By: M. Moore n & L. Jaykus n

author keywords: Norovirus; Disinfection; Capsid functionality; Histo-blood group antigens; Receptor binding assay
MeSH headings : Amino Acid Sequence / genetics; Blood Group Antigens / immunology; Blood Group Antigens / isolation & purification; Capsid Proteins / blood; Gastroenteritis / diagnosis; Gastroenteritis / virology; Genotype; Humans; Norovirus / genetics; Norovirus / immunology; Norovirus / isolation & purification; Norovirus / pathogenicity; Protein Binding
TL;DR: A streamlined version of a receptor-binding assay with minimal time-to-result while maintaining accuracy and high throughput is presented, validating assay performance for physical and chemical inactivation treatments of a norovirus GII. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Development of a Recombinase Polymerase Amplification Assay for Detection of Epidemic Human Noroviruses

SCIENTIFIC REPORTS, 7.

By: M. Moore n & L. Jaykus n

MeSH headings : Caliciviridae Infections / diagnosis; Caliciviridae Infections / genetics; Epidemics / prevention & control; Humans; Norovirus / genetics; Norovirus / isolation & purification; Real-Time Polymerase Chain Reaction / methods; Recombinases / analysis; Recombinases / genetics; Reverse Transcriptase Polymerase Chain Reaction / methods
TL;DR: The reported RT-RPA method shows promise for sensitive point-of-care detection of epidemic human norovirus detection, and is the fastest human Norovirus amplification method to date. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Human norovirus binding to select bacteria representative of the human gut microbiota

PLOS ONE, 12(3).

By: E. Almand  n, M. Moore n, J. Outlaw n & L. Jaykus n

MeSH headings : Bacillus / isolation & purification; Bacillus / metabolism; Citrobacter / isolation & purification; Citrobacter / metabolism; Culture Media / chemistry; Enterobacter cloacae / isolation & purification; Enterobacter cloacae / metabolism; Enterococcus faecium / isolation & purification; Enterococcus faecium / metabolism; Feces / microbiology; Fimbriae, Bacterial / chemistry; Fimbriae, Bacterial / metabolism; Fimbriae, Bacterial / ultrastructure; Gastrointestinal Microbiome / physiology; Hafnia alvei / isolation & purification; Hafnia alvei / metabolism; Humans; Klebsiella / isolation & purification; Klebsiella / metabolism; Microbial Interactions; Norovirus / metabolism; Norovirus / ultrastructure; Staphylococcus aureus / isolation & purification; Staphylococcus aureus / metabolism
TL;DR: The findings reported here further elucidate and inform the dynamics between human noroviruses and enteric bacteria with implications for norovirus pathogenesis. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2017 review

Norovirus Binding to Ligands Beyond Histo-Blood Group Antigens

[Review of ]. FRONTIERS IN MICROBIOLOGY, 8.

By: E. Almand  n, M. Moore n & L. Jaykus n

author keywords: norovirus; histo-blood group antigens; virus-bacteria interaction; transkingdom; enteric virus
TL;DR: This review seeks to supplement the already well-covered HBGA-norovirus literature by covering non-HBGA human norovirus ligands and inhibitors to provide investigators with a more comprehensive view of norov virus ligands. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2017 journal article

Recombinase polymerase amplification: a promising point-of-care detection method for enteric viruses

FUTURE VIROLOGY, 12(8), 421–429.

By: M. Moore n & L. Jaykus n

author keywords: detection; enteric virus; in-field; point-of-care; recombinase polymerase amplification
TL;DR: This report reviews the use of recombinase polymerase amplification for virus detection, showing that the method has favorable fundamental properties supporting its promise for rapid point-of-care detection of enteric viruses. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2017 review

Virus-bacteria interactions: An emerging topic in human infection

[Review of ]. Viruses-Basel, 9(3).

By: E. Almand, M. Moore & L. Jaykus

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Efficacy of a disinfectant containing silver dihydrogen citrate against GI.6 and GII.4 human norovirus

JOURNAL OF APPLIED MICROBIOLOGY, 122(1), 78–86.

By: C. Manuel n, M. Moore n & L. Jaykus n

author keywords: antimicrobials; disinfection; environmental; food safety; norovirus; viruses
MeSH headings : Capsid Proteins / genetics; Citrates / pharmacology; Disinfectants / pharmacology; Humans; Norovirus / drug effects; Norovirus / genetics; Real-Time Polymerase Chain Reaction; Silver Compounds / pharmacology
TL;DR: This study tested the efficacy of an antimicrobial product containing a blend of silver ions and citric acid (silver dihydrogen citrate; SDC) against GI. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2016 journal article

Human Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle Functionality

MSPHERE, 1(6).

By: M. Moore n, B. Bobay n, B. Mertens n & L. Jaykus n

author keywords: aptamer; GII.4; histo-blood group antigen; infectivity; noroviruses
TL;DR: A hitherto unexplored property of a different type of ligand, a nucleic acid aptamer, to mimic receptor binding behavior and assess capsid functionality for a selected strain of norovirus is reported, suggesting that other aptamers may show promise in the study of other fastidious microorganisms. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 journal article

Destruction of the Capsid and Genome of GII.4 Human Norovirus Occurs during Exposure to Metal Alloys Containing Copper

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81(15), 4940–4946.

By: C. Manuel n, M. Moore n & L. Jaykus n

MeSH headings : Alloys / toxicity; Blotting, Western; Capsid / drug effects; Copper / toxicity; Feces / virology; Genome, Viral / drug effects; Humans; Microscopy, Electron, Transmission; Norovirus / drug effects; Norovirus / physiology; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Virus Attachment / drug effects
TL;DR: It is suggested that copper surfaces destroy HuNoV and may be useful in preventing environmental transmission of the virus in at-risk settings. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 journal article

Generation and characterization of nucleic acid aptamers targeting the capsid P domain of a human norovirus GII.4 strain

JOURNAL OF BIOTECHNOLOGY, 209, 41–49.

By: M. Moore n, B. Escudero-Abarca n, S. Suh n & L. Jaykus n

author keywords: SELEX; Aptamer; Norovirus; Molecular detection; Viral diagnostics
MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Capsid Proteins / genetics; Capsid Proteins / metabolism; Feces / virology; Humans; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; SELEX Aptamer Technique / methods; Sensitivity and Specificity
TL;DR: This is the first demonstration of human NoV P domain protein as a functional target for the selection of nucleic acid aptamers that specifically bind and broadly recognize diversehuman NoV strains. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 article

Human Norovirus as a Foodborne Pathogen: Challenges and Developments

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 6, Vol. 6, pp. 411–433.

By: M. Moore n, R. Goulter n & L. Jaykus n

author keywords: epidemiology; detection; evolution; cell culture; infectivity
MeSH headings : Animals; Caliciviridae Infections / epidemiology; Caliciviridae Infections / virology; Cell Line; Food / virology; Gastroenteritis / epidemiology; Gastroenteritis / virology; Humans; Norovirus / classification; Norovirus / pathogenicity; Phylogeny
TL;DR: A brief overview of NoVs and their genetic structure is provided and the challenges and recent developments related to human NoVs regarding viral evolution, transmission, epidemiology, outbreak identification, cultivation, animal and human models, and detection are presented. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2014 journal article

Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains

PLOS ONE, 9(9).

By: B. Escudero-Abarca n, S. Suh n, M. Moore n, H. Dwivedi n & L. Jaykus n

MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Bacteriological Techniques / methods; DNA, Viral / chemistry; DNA, Viral / metabolism; Feces / virology; Food Microbiology; Humans; Lettuce / virology; Molecular Structure; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; Sensitivity and Specificity
TL;DR: These ssDNA aptamer candidates show promise as broadly reactive reagents for use in HuNoV capture and detection assays in various sample types. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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