Mary Erb

College of Engineering

Works (2)

Updated: July 5th, 2023 14:43

2020 journal article

Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects

Journal of Colloid and Interface Science, 577, 406–418.

By: S. Nandi n, L. Sommerville *, K. Nellenbach n, E. Mihalko n, M. Erb n, D. Freytes n, M. Hoffman *, D. Monroe *, A. Brown n 

author keywords: Fibrin; Biomimetic; Platelet; Hemophilia; Biomaterials
MeSH headings : Blood Coagulation; Blood Platelets; Fibrin; Plasma; Wound Healing
TL;DR: PLPs improved clot network density, force generation, and stiffness, and promoted fibroblast migration within an in vitro model of early wound healing under hemophilic conditions, indicating that PLPs could provide a biomimetic platform for improving wound healing events in disease conditions that cause deficient fibrin network formation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 24, 2020

2020 journal article

Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair

ACS Biomaterials Science & Engineering, 6(5), 3026–3036.

By: S. Nandi n, K. Mohanty n, K. Nellenbach n, M. Erb n, M. Muller n  & A. Brown n 

author keywords: biomimetic; fibrin; wound healing clot retraction; artificial platelet
MeSH headings : Blood Coagulation; Blood Platelets; Clot Retraction; Fibrin; Wound Healing
TL;DR: Application of ultrasound in combination with a subtherapeutic dosage of PLPs resulted in increased clot density and stiffness, improved fibroblast migration in vitro and increased epidermal thickness and angiogenesis in vivo, indicating that this combination therapy has potential to facilitate multiphase pro-healing outcomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 8, 2020

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