Michael Sherrill
College of Sciences
Works (1)
Updated: June 18th, 2023 22:55
2021 journal article
K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15
MOLECULAR BIOLOGY OF THE CELL, 32(22).
Contributors: M. Elting n
Ed(s): C. Walczak
MeSH headings : Cell Cycle Proteins / genetics; Cell Cycle Proteins / metabolism; Cell Line; Humans; Kidney / cytology; Kinesins / antagonists & inhibitors; Kinesins / genetics; Kinesins / metabolism; Kinetochores; Microtubules / metabolism; Spindle Apparatus / physiology; Time-Lapse Imaging
TL;DR:
The data suggest that forces holding k-fibers together are of similar magnitude to other spindle forces, and that Kif15, acting as a microtubule crosslinker, helps fortify and repair k-Fibers.
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Added: February 21, 2022