@article{heiranian_fan_wang_lu_elimelech_2023, title={Mechanisms and models for water transport in reverse osmosis membranes: history, critical assessment, and recent developments}, volume={10}, ISSN={["1460-4744"]}, DOI={10.1039/d3cs00395g}, abstractNote={Water scarcity is one of the greatest societal challenges facing humanity.}, journal={CHEMICAL SOCIETY REVIEWS}, author={Heiranian, Mohammad and Fan, Hanqing and Wang, Li and Lu, Xinglin and Elimelech, Menachem}, year={2023}, month={Oct} }
 @article{heiranian_noh_aluru_2021, title={Dynamic and weak electric double layers in ultrathin nanopores}, volume={154}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85103766678&partnerID=MN8TOARS}, DOI={10.1063/5.0048011}, abstractNote={The unique properties of aqueous electrolytes in ultrathin nanopores have drawn a great deal of attention in a variety of applications, such as power generation, water desalination, and disease diagnosis. Inside the nanopore, at the interface, properties of ions differ from those predicted by the classical ionic layering models (e.g., Gouy–Chapman electric double layer) when the thickness of the nanopore approaches the size of a single atom (e.g., nanopores in a single-layer graphene membrane). Here, using extensive molecular dynamics simulations, the structure and dynamics of aqueous ions inside nanopores are studied for different thicknesses, diameters, and surface charge densities of carbon-based nanopores [ultrathin graphene and finite-thickness carbon nanotubes (CNTs)]. The ion concentration and diffusion coefficient in ultrathin nanopores show no indication of the formation of a Stern layer (an immobile counter-ionic layer) as the counter-ions and nanopore atoms are weakly correlated in time compared to the strong correlation observed in thick nanopores. The weak correlation observed in ultrathin nanopores is indicative of a weak adsorption of counter-ions onto the surface compared to that of thick pores. The vanishing counter-ion adsorption (ion–wall correlation) in ultrathin nanopores leads to several orders of magnitude shorter ionic residence times (picoseconds) compared to the residence times in thick CNTs (seconds). The results of this study will help better understand the structure and dynamics of aqueous ions in ultrathin nanopores.}, number={13}, journal={Journal of Chemical Physics}, author={Heiranian, M. and Noh, Y. and Aluru, N.R.}, year={2021} }
 @article{zhou_heiranian_yang_epsztein_gong_white_hu_kim_elimelech_2021, title={Selective Fluoride Transport in Subnanometer TiO<sub>2</sub>Pores}, volume={15}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85118222639&partnerID=MN8TOARS}, DOI={10.1021/acsnano.1c07210}, abstractNote={Synthesizing nanopores which mimic the functionality of ion-selective biological channels has been a challenging yet promising approach to advance technologies for precise ion-ion separations. Inspired by the facilitated fluoride (F-) permeation in the biological fluoride channel, we designed a highly fluoride-selective TiO2 film using the atomic layer deposition (ALD) technique. The subnanometer voids within the fabricated TiO2 film (4 Å < d < 12 Å, with two distinct peaks at 5.5 and 6.5 Å), created by the hindered diffusion of ALD precursors (d = 7 Å), resulted in more than eight times faster permeation of sodium fluoride compared to other sodium halides. We show that the specific Ti-F interactions compensate for the energy penalty of F- dehydration during the partitioning of F- ions into the pore and allow for an intrapore accumulation of F- ions. Concomitantly, the accumulation of F- ions on the pore walls also enhances the transport of sodium (Na+) cations due to electrostatic interactions. Molecular dynamics simulations probing the ion concentration and mobility within the TiO2 pore further support our proposed mechanisms for the selective F- transport and enhanced Na+ permeation in the TiO2 film. Overall, our work provides insights toward the design of ion-selective nanopores using the ALD technique.}, number={10}, journal={ACS Nano}, author={Zhou, X. and Heiranian, M. and Yang, M. and Epsztein, R. and Gong, K. and White, C.E. and Hu, S. and Kim, J.-H. and Elimelech, M.}, year={2021}, pages={16828–16838} }
 @article{song_heiranian_elimelech_2021, title={True driving force and characteristics of water transport in osmotic membranes}, volume={520}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85115140956&partnerID=MN8TOARS}, DOI={10.1016/j.desal.2021.115360}, abstractNote={Diffusion cannot be a major water transport mechanism in osmotic membranes because of the lack of true water concentration gradient within the membrane. Due to the semipermeable property of osmotic membranes, water concentration in the membrane is virtually constant because of the absence of salts. The recently confirmed porous structure of the skin layer of osmotic membranes cannot support the basis to exclude bulk water flow in the membrane as assumed in the classic solution-diffusion model. Herein we demonstrate that the concentration difference of water at the membrane-solution interface manifests itself as a negative hydraulic pressure in the membrane. Hence, the only possible driving force for water movement in osmotic membranes is hydraulic pressure gradient. Osmotically driven membrane processes are characterized with negative pressure within the membrane below the water vapor pressure, inevitably leading to the formation of vapor or small bubbles within the membrane matrix. This phenomenon is expected to markedly reduce the effectiveness of osmotic pressure as a driving force for water transport. Delineation of the breakdown and possible restoration of water continuity under negative pressure is essential for proper understanding of the principles governing water transport in osmotic membranes.}, journal={Desalination}, author={Song, L. and Heiranian, M. and Elimelech, M.}, year={2021} }
 @article{hwang_park_heiranian_taqieddin_you_faramarzi_pak_zande_aluru_bashir_2021, title={Ultrasensitive Detection of Dopamine, IL-6 and SARS-CoV-2 Proteins on Crumpled Graphene FET Biosensor}, volume={6}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85113628733&partnerID=MN8TOARS}, DOI={10.1002/admt.202100712}, abstractNote={Abstract}, number={11}, journal={Advanced Materials Technologies}, author={Hwang, M.T. and Park, I. and Heiranian, M. and Taqieddin, A. and You, S. and Faramarzi, V. and Pak, A.A. and Zande, A.M. and Aluru, N.R. and Bashir, R.}, year={2021} }
 @article{snapp_heiranian_hwang_bashir_aluru_nam_2020, title={Current understanding and emerging applications of 3D crumpling mediated 2D material-liquid interactions}, volume={24}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85087668427&partnerID=MN8TOARS}, DOI={10.1016/j.cossms.2020.100836}, abstractNote={Three dimensional (3D) crumpling of two dimensional (2D) materials provides new opportunities to modulate mechanical, optical, surface, and chemical properties. However, investigation of the effect of 3D crumpling on 2D material liquid interaction has been limited. In this perspective, we will review crumple/texture induced heterogeneous surface properties including chemical modification, energy corrugation, and electronic structure perturbation which may modulate fluid interaction. We will then describe simulations of fluid interaction in systems resembling 3D textured 2D materials, principally nanotubes, which have begun to substantiate perturbations to fluid structure driven by texture induced modification of the 2D material surface. Furthermore, we will detail current experimental understanding of how texture induced modulation of interactions with pure solvent affect macroscale wetting characteristics including textured driven transitions in water contact from Wentzel to Cassie Baxter states. Following this discussion of how texturing affects the interaction of 2D materials with pure solvent, we will detail cutting edge explorations of how texturing modifies interaction with ions and other chemical species dispersed in solvent phases. Particular focus will be placed on recent simulations of aqueous phase molecular interaction with crumpled 2D materials which show that crumpling increases the thickness of the electrical double layer (EDL) formed near a 2D material surface. This increased EDL thickness has allowed for the development of biomolecule sensors with gigantic sensitivity and the monitoring and templating of cells including neurons and myotubes. Sill, considerable work is needed to elucidate the effect of different crumpling geometries on the local properties of the full range of 2D materials, how these variation in local properties perturb fluid structure and molecular interaction, and how these tuned interactions enable diverse opportunities such as sensing, energy storage, and control of biological interaction.}, number={3}, journal={Current Opinion in Solid State and Materials Science}, author={Snapp, P. and Heiranian, M. and Hwang, M.T. and Bashir, R. and Aluru, N.R. and Nam, S.}, year={2020} }
 @article{taqieddin_heiranian_aluru_2020, title={Interfacial Properties of Water on Hydrogenated and Fluorinated Graphene Surfaces: Parametrization of Nonbonded Interactions}, volume={124}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85095583767&partnerID=MN8TOARS}, DOI={10.1021/acs.jpcc.0c05951}, abstractNote={The properties of water interfacing with functionalized 2D materials play a crucial role in the design and development of high-performance nanofluidic devices. Developing nonbonding force field par...}, number={39}, journal={Journal of Physical Chemistry C}, author={Taqieddin, A. and Heiranian, M. and Aluru, N.R.}, year={2020}, pages={21467–21475} }
 @article{heiranian_aluru_2020, title={Nanofluidic Transport Theory with Enhancement Factors Approaching One}, volume={14}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85077680711&partnerID=MN8TOARS}, DOI={10.1021/acsnano.9b04328}, abstractNote={High performance water transport in nanopores has drawn a great deal of attention in a variety of applications, such as water desalination, power generation and biosensing. High water transport enhancement factors in carbon-based nanopores have been reported over the classical Hagen-Poiseuille (HP) equation which does not account for the physics of transport at molecular scale. Instead, comparing the experimentally measured transport rates to that of a theory, that accounts for the microscopic physics of transport, would result in enhancement factors approaching unity. Such a theory is currently missing. Here, molecular corrections are introduced into HP equation by considering the variation of key hydrodynamical properties (viscosity and friction) with thickness and diameter of pores in ultrathin graphene and finite-length carbon nanotubes (CNTs) using Green-Kubo relations and molecular dynamics (MD) simulations. The corrected HP (CHP) theory, successfully predicts the permeation rates from non-equilibrium MD pressure driven flows. The previously reported enhancement factors over no-slip HP (of the order of 1000) approach unity when the permeations are normalized by the CHP flow rates. The results of our study will help better understand nanoscale flows in carbon-based pores and tubes.}, number={1}, journal={ACS Nano}, author={Heiranian, M. and Aluru, N.R.}, year={2020}, pages={272–281} }
 @article{heiranian_taqieddin_aluru_2020, title={Revisiting Sampson's theory for hydrodynamic transport in ultrathin nanopores}, volume={2}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85103764730&partnerID=MN8TOARS}, DOI={10.1103/PhysRevResearch.2.043153}, abstractNote={Sampson's theory for hydrodynamic resistance across a zero-length orifice was developed over a century ago. Although a powerful theory for entrance/exit resistance in nanopores, it lacks accuracy for relatively small-radius pores since it does not account for the molecular interface chemistry. Here, Sampson's theory is revisited for the finite slippage and interfacial viscosity variation near the pore wall. The corrected Sampson's theory can accurately predict the hydrodynamic resistance from molecular dynamics simulations of ultrathin nanopores.6 MoreReceived 19 February 2020Accepted 1 October 2020DOI:https://doi.org/10.1103/PhysRevResearch.2.043153Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.Published by the American Physical SocietyPhysics Subject Headings (PhySH)Research AreasFlows in porous mediaGeophysical fluid dynamicsGranular flowsInteratomic & molecular potentialsInterfacial flowsMicrofluidicsVan der Waals interactionFluid DynamicsAtomic, Molecular & Optical}, number={4}, journal={Physical Review Research}, author={Heiranian, M. and Taqieddin, A. and Aluru, N.R.}, year={2020} }
 @article{hwang_heiranian_kim_you_leem_taqieddin_faramarzi_jing_park_zande_et al._2020, title={Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors}, volume={11}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85082380883&partnerID=MN8TOARS}, DOI={10.1038/s41467-020-15330-9}, abstractNote={Abstract}, number={1}, journal={Nature Communications}, author={Hwang, M.T. and Heiranian, M. and Kim, Y. and You, S. and Leem, J. and Taqieddin, A. and Faramarzi, V. and Jing, Y. and Park, I. and Zande, A.M. and et al.}, year={2020} }
 @article{kwon_choi_heiranian_kim_chang_knapp_wang_kim_aluru_park_et al._2019, title={Electrical Double Layer of Supported Atomically Thin Materials}, volume={19}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85069621468&partnerID=MN8TOARS}, DOI={10.1021/acs.nanolett.9b01563}, abstractNote={The electrical double layer (EDL), consisting of two parallel layers of opposite charges, is foundational to many interfacial phenomena and unique in atomically-thin materials. An important but unanswered question is how the 'transparency' of atomically thin materials to their substrates influences the formation of the EDL. Here, we report that the EDL of graphene is directly affected by the surface energy of the underlying substrates. Cyclic voltammetry and electrochemical impedance spectroscopy measurements demonstrate that graphene on hydrophobic substrates exhibits an anomalously low EDL capacitance, much lower than what was previously measured for highly oriented pyrolytic graphite, suggesting disturbance of the EDL ('disordered EDL') formation due to the substrate-induced hydrophobicity to graphene. Similarly, electrostatic gating using EDL of graphene field-effect transistors shows much lower transconductance level or even no gating for graphene on hydrophobic substrates, further supporting our hypothesis. Molecular dynamics simulations show that the EDL structure of graphene on a hydrophobic substrate is disordered, caused by the disruption of water dipole assemblies. Our study advances understanding of EDL in atomically-thin limit.}, number={7}, journal={Nano Letters}, author={Kwon, S.S. and Choi, J. and Heiranian, M. and Kim, Y. and Chang, W.J. and Knapp, P.M. and Wang, M.C. and Kim, J.M. and Aluru, N.R. and Park, W.I. and et al.}, year={2019}, pages={4588–4593} }
 @article{barati farimani_heiranian_aluru_2018, title={Identification of amino acids with sensitive nanoporous MoS<sub>2</sub>: towards machine learning-based prediction}, volume={2}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85059441333&partnerID=MN8TOARS}, DOI={10.1038/s41699-018-0060-8}, abstractNote={Abstract}, number={1}, journal={npj 2D Materials and Applications}, author={Barati Farimani, A. and Heiranian, M. and Aluru, N.R.}, year={2018} }
 @article{zhang_heiranian_janicek_budrikis_zapperi_huang_johnson_aluru_lyding_mason_2018, title={Strain Modulation of Graphene by Nanoscale Substrate Curvatures: A Molecular View}, volume={18}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85043995823&partnerID=MN8TOARS}, DOI={10.1021/acs.nanolett.8b00273}, abstractNote={Spatially nonuniform strain is important for engineering the pseudomagnetic field and band structure of graphene. Despite the wide interest in strain engineering, there is still a lack of control on device-compatible strain patterns due to the limited understanding of the structure-strain relationship. Here, we study the effect of substrate corrugation and curvature on the strain profiles of graphene via combined experimental and theoretical studies of a model system: graphene on closely packed SiO2 nanospheres with different diameters (20-200 nm). Experimentally, via quantitative Raman analysis, we observe partial adhesion and wrinkle features and find that smaller nanospheres induce larger tensile strain in graphene; theoretically, molecular dynamics simulations confirm the same microscopic structure and size dependence of strain and reveal that a larger strain is caused by a stronger, inhomogeneous interaction force between smaller nanospheres and graphene. This molecular-level understanding of the strain mechanism is important for strain engineering of graphene and other two-dimensional materials.}, number={3}, journal={Nano Letters}, author={Zhang, Y. and Heiranian, M. and Janicek, B. and Budrikis, Z. and Zapperi, S. and Huang, P.Y. and Johnson, H.T. and Aluru, N.R. and Lyding, J.W. and Mason, N.}, year={2018}, pages={2098–2104} }
 @article{zhang_heiranian_janicek_budrikis_zapperi_huang_johnson_aluru_lyding_mason_2018, title={Strain modulation of graphene by nanoscale substrate curvatures: A molecular view}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85094483241&partnerID=MN8TOARS}, journal={arXiv}, author={Zhang, Y. and Heiranian, M. and Janicek, B. and Budrikis, Z. and Zapperi, S. and Huang, P.Y. and Johnson, H.T. and Aluru, N.R. and Lyding, J.W. and Mason, N.}, year={2018} }
 @article{barati farimani_heiranian_min_aluru_2017, title={Antibody Subclass Detection Using Graphene Nanopores}, volume={8}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85016962617&partnerID=MN8TOARS}, DOI={10.1021/acs.jpclett.7b00385}, abstractNote={Solid-state nanopores are promising for label-free protein detection. The large thickness, ranging from several tens of nanometers to micrometers and larger, of solid-state nanopores prohibits atomic-scale scanning or interrogation of proteins. Here, a single-atom thick graphene nanopore is shown to be highly capable of sensing and discriminating between different subclasses of IgG antibodies despite their minor and subtle variation in atomic structure. Extensive molecular dynamics (MD) simulations, rigorous statistical analysis with a total aggregate simulation time of 2.7 μs, supervised machine learning (ML), and classification techniques are employed to distinguish IgG2 from IgG3. The water flux and ionic current during IgG translocation reveal distinct clusters for IgG subclasses facilitating an additional recognition mechanism. In addition, the histogram of ionic current for each segment of IgG can provide high-resolution spatial detection. Our results show that nanoporous graphene can be used to detect and distinguish antibody subclasses with good accuracy.}, number={7}, journal={Journal of Physical Chemistry Letters}, author={Barati Farimani, A. and Heiranian, M. and Min, K. and Aluru, N.R.}, year={2017}, pages={1670–1676} }
 @article{heiranian_wu_aluru_2017, title={Molybdenum disulfide and water interaction parameters}, volume={147}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85029438448&partnerID=MN8TOARS}, DOI={10.1063/1.5001264}, abstractNote={Understanding the interaction between water and molybdenum disulfide (MoS2) is of crucial importance to investigate the physics of various applications involving MoS2 and water interfaces. An accurate force field is required to describe water and MoS2 interactions. In this work, water–MoS2 force field parameters are derived using the high-accuracy random phase approximation (RPA) method and validated by comparing to experiments. The parameters obtained from the RPA method result in water–MoS2 interface properties (solid-liquid work of adhesion) in good comparison to the experimental measurements. An accurate description of MoS2-water interaction will facilitate the study of MoS2 in applications such as DNA sequencing, sea water desalination, and power generation.}, number={10}, journal={Journal of Chemical Physics}, author={Heiranian, M. and Wu, Y. and Aluru, N.R.}, year={2017} }
 @article{farimani_heiranian_aluru_2016, title={Nano-electro-mechanical pump: Giant pumping of water in carbon nanotubes}, volume={6}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84969951823&partnerID=MN8TOARS}, DOI={10.1038/srep26211}, abstractNote={Abstract}, journal={Scientific Reports}, author={Farimani, A.B. and Heiranian, M. and Aluru, N.R.}, year={2016} }
 @article{feng_graf_liu_ovchinnikov_dumcenco_heiranian_nandigana_aluru_kis_radenovic_2016, title={Single-layer MoS<sub>2</sub> nanopores as nanopower generators}, volume={536}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84978127640&partnerID=MN8TOARS}, DOI={10.1038/nature18593}, abstractNote={Blue energy is a desirable renewable resource, involving the osmotic transport of ions through a membrane from seawater to fresh water; here, nanopores have been created in two-dimensional molybdenum-disulfide membranes, and shown to generate a substantial osmotic power output. Osmotic power generation is a promising renewable energy source. This study demonstrates the use of single-layer molybdenum disulfide (MoS2) nanopores as osmotic nanogenerators. The transport of water through a membrane scales inversely with membrane thickness, so atomically thin materials should provide the ideal medium to host the nanopores in an osmotic power generator. Aleksandra Radenovic and colleagues produced nanopores in two-dimensional MoS2 and, using a salt gradient across a single nanopore, generated a power output per area orders of magnitude greater than that previously reported for nanotubes. They also show that a chemical potential gradient across a single nanopore in MoS2 can generate enough power to operate a single-layer MoS2 transistor. Making use of the osmotic pressure difference between fresh water and seawater is an attractive, renewable and clean way to generate power and is known as ‘blue energy’1,2,3. Another electrokinetic phenomenon, called the streaming potential, occurs when an electrolyte is driven through narrow pores either by a pressure gradient4 or by an osmotic potential resulting from a salt concentration gradient5. For this task, membranes made of two-dimensional materials are expected to be the most efficient, because water transport through a membrane scales inversely with membrane thickness5,6,7. Here we demonstrate the use of single-layer molybdenum disulfide (MoS2) nanopores as osmotic nanopower generators. We observe a large, osmotically induced current produced from a salt gradient with an estimated power density of up to 106 watts per square metre—a current that can be attributed mainly to the atomically thin membrane of MoS2. Low power requirements for nanoelectronic and optoelectric devices can be provided by a neighbouring nanogenerator that harvests energy from the local environment8,9,10,11—for example, a piezoelectric zinc oxide nanowire array8 or single-layer MoS2 (ref. 12). We use our MoS2 nanopore generator to power a MoS2 transistor, thus demonstrating a self-powered nanosystem.}, number={7615}, journal={Nature}, author={Feng, J. and Graf, M. and Liu, K. and Ovchinnikov, D. and Dumcenco, D. and Heiranian, M. and Nandigana, V. and Aluru, N.R. and Kis, A. and Radenovic, A.}, year={2016}, pages={197–200} }
 @article{venkatesan_lee_farimani_heiranian_collier_aluru_sarles_2015, title={Adsorption Kinetics Dictate Monolayer Self-Assembly for Both Lipid-In and Lipid-Out Approaches to Droplet Interface Bilayer Formation}, volume={31}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84948697689&partnerID=MN8TOARS}, DOI={10.1021/acs.langmuir.5b02293}, abstractNote={The droplet interface bilayer (DIB)--a method to assemble planar lipid bilayer membranes between lipid-coated aqueous droplets--has gained popularity among researchers in many fields. Well-packed lipid monolayer on aqueous droplet-oil interfaces is a prerequisite for successfully assembling DIBs. Such monolayers can be achieved by two different techniques: "lipid-in", in which phospholipids in the form of liposomes are placed in water, and "lipid-out", in which phospholipids are placed in oil as inverse micelles. While both approaches are capable of monolayer assembly needed for bilayer formation, droplet pairs assembled with these two techniques require significantly different incubation periods and exhibit different success rates for bilayer formation. In this study, we combine experimental interfacial tension measurements with molecular dynamics simulations of phospholipids (DPhPC and DOPC) assembled from water and oil origins to understand the differences in kinetics of monolayer formation. With the results from simulations and by using a simplified model to analyze dynamic interfacial tensions, we conclude that, at high lipid concentrations common to DIBs, monolayer formation is simple adsorption controlled for lipid-in technique, whereas it is predominantly adsorption-barrier controlled for the lipid-out technique due to the interaction of interface-bound lipids with lipid structures in the subsurface. The adsorption barrier established in lipid-out technique leads to a prolonged incubation time and lower bilayer formation success rate, proving a good correlation between interfacial tension measurements and bilayer formation. We also clarify that advective flow expedites monolayer formation and improves bilayer formation success rate by disrupting lipid structures, rather than enhancing diffusion, in the subsurface and at the interface for lipid-out technique. Additionally, electrical properties of DIBs formed with varying lipid placement and type are characterized.}, number={47}, journal={Langmuir}, author={Venkatesan, G.A. and Lee, J. and Farimani, A.B. and Heiranian, M. and Collier, C.P. and Aluru, N.R. and Sarles, S.A.}, year={2015}, pages={12883–12893} }
 @article{farimani_heiranian_aluru_2015, title={Electromechanical signatures for DNA sequencing through a mechanosensitive nanopore}, volume={6}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84923349577&partnerID=MN8TOARS}, DOI={10.1021/jz5025417}, abstractNote={Biological nanopores have been extensively used for DNA base detection since these pores are widely available and tunable through mutations. Distinguishing bases of nucleic acids by passing them through nanopores has so far primarily relied on electrical signals-specifically, ionic currents through the nanopores. However, the low signal-to-noise ratio makes detection of ionic currents difficult. In this study, we show that the initially closed mechanosensitive channel of large conductance (MscL) protein pore opens for single-stranded DNA (ssDNA) translocation under an applied electric field. As each nucleotide translocates through the pore, a unique mechanical signal is observed-specifically, the tension in the membrane containing the MscL pore is different for each nucleotide. In addition to the membrane tension, we found that the ionic current is also different for the four nucleotide types. The initially closed MscL adapts its opening for nucleotide translocation due to the flexibility of the pore. This unique operation of MscL provides single nucleotide resolution in both electrical and mechanical signals. Finally, we also show that the speed of DNA translocation is roughly 1 order of magnitude slower in MscL compared to Mycobacterium smegmatis porin A (MspA), suggesting MscL to be an attractive protein pore for DNA sequencing.}, number={4}, journal={Journal of Physical Chemistry Letters}, author={Farimani, A.B. and Heiranian, M. and Aluru, N.R.}, year={2015}, pages={650–657} }
 @article{farimani_heiranian_aluru_2015, title={Erratum: Electromechanical signatures for DNA sequencing through a mechanosensitive nanopore (Journal Physical Chemistry Letters (2015) 6:4 (650-657) DOI:10.1021/jz5025417)}, volume={6}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84942592546&partnerID=MN8TOARS}, DOI={10.1021/acs.jpclett.5b01691}, abstractNote={ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to “Electromechanical Signatures for DNA Sequencing through a Mechanosensitive Nanopore”A. Barati Farimani, M. Heiranian, and N. R. Aluru*Cite this: J. Phys. Chem. Lett. 2015, 6, 17, 3365Publication Date (Web):August 13, 2015Publication History Published online13 August 2015Published inissue 3 September 2015https://doi.org/10.1021/acs.jpclett.5b01691Copyright © 2015 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views416Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (166 KB) Get e-Alerts Get e-Alerts}, number={13}, journal={Journal of Physical Chemistry Letters}, author={Farimani, A.B. and Heiranian, M. and Aluru, N.R.}, year={2015}, pages={3365} }
 @article{heiranian_farimani_aluru_2015, title={Water desalination with a single-layer MoS 2 nanopore}, volume={6}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84944338960&partnerID=MN8TOARS}, DOI={10.1038/ncomms9616}, abstractNote={Abstract}, journal={Nature Communications}, author={Heiranian, M. and Farimani, A.B. and Aluru, N.R.}, year={2015} }