Works (66)

Updated: July 26th, 2023 21:14

2009 journal article

Candidate Gene Association Mapping of Arabidopsis Flowering Time

GENETICS, 183(1), 325–335.

By: I. Ehrenreich n, Y. Hanzawa*, L. Chou*, J. Roe*, P. Kover* & M. Purugganan*

MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Chromosome Mapping; Crosses, Genetic; Flowers / genetics; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Gene Regulatory Networks; Genes, Plant / physiology; Genetic Linkage; Genotype; Polymorphism, Single Nucleotide; Time Factors
TL;DR: Using structured association techniques, it is found that haplotype-tagging SNPs in 27 flowering time genes show significant associations in various trait/environment combinations, and it is conservatively estimated that ∼4–14% of known floweringTime genes may harbor common alleles that contribute to natural variation in this life history trait. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Complex Rearrangements Lead to Novel Chimeric Gene Fusion Polymorphisms at the Arabidopsis thaliana MAF2-5 Flowering Time Gene Cluster

MOLECULAR BIOLOGY AND EVOLUTION, 26(3), 699–711.

By: A. Caicedo*, C. Richards*, I. Ehrenreich n & M. Purugganan*

author keywords: alternative splicing; gene origin; gene fusion; MADS-box; quantitative trait loci
MeSH headings : Arabidopsis / genetics; Arabidopsis Proteins / genetics; Flowers / genetics; Gene Fusion; Gene Rearrangement; Genes, Plant; MADS Domain Proteins / genetics; Multigene Family; Polymorphism, Genetic; Polymorphism, Single Nucleotide
TL;DR: The finding that complex rearrangements within gene clusters, such as those observed for MAF2, might play a role in the generation of ecologically important phenotypic variation, emphasize the need for emerging high throughput genotyping and sequencing techniques to correctly reconstruct gene chimeras and other complex polymorphisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Functional and geographical differentiation of candidate balanced polymorphisms in Arabidopsis thaliana

MOLECULAR ECOLOGY, 18(13), 2844–2855.

By: J. Reininga n, D. Nielsen n & M. Purugganan*

author keywords: adaptation; balancing selection; population genetics
MeSH headings : Alleles; Arabidopsis / genetics; Arabidopsis Proteins / genetics; DNA, Plant / genetics; Gene Expression Regulation, Plant; Genes, Plant; Genetics, Population; Genome, Plant; Polymorphism, Genetic; Selection, Genetic
TL;DR: The data support a hypothesis of balancing selection at all three candidate loci and provide a basis for more detailed functional work by identifying possible functional differences that might be selectively maintained. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 article

Darwinian selection on a selfing locus (vol 306, pg 2081, 2004)

Science, Vol. 320, pp. 176–176.

By: K. Shimizu, J. Reininga, A. Caicedo, C. Mays, R. Moore, K. Olsen, S. Ruzsa, G. Coop, C. Bustamante, M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Independent origins of self-compatibility in Arabidopsis thaliana

MOLECULAR ECOLOGY, 17(2), 704–714.

author keywords: Arabidopsis thaliana; evolutionary genomics; molecular adaptation; reproductive strategies; self-incompatibility; S locus
MeSH headings : Amino Acid Sequence; Arabidopsis / classification; Arabidopsis / genetics; Arabidopsis Proteins / genetics; DNA, Plant / chemistry; DNA, Plant / genetics; Evolution, Molecular; Fertility / genetics; Genes, Plant; Genetics, Population; Genome, Plant; Genotype; Haplotypes; Molecular Sequence Data; Phylogeny; Pseudogenes; Sequence Analysis, DNA; Sequence Homology, Amino Acid
TL;DR: The results suggest that self‐compatibility, which appears to be fixed in this species, arose multiple times with different genetic bases, and indicates that a species‐specific trait is associated with parallel evolution at the molecular level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Sequence variation of microRNAs and their binding sites in Arabidopsis

PLANT PHYSIOLOGY, 146(4), 1974–1982.

By: I. Ehrenreich n & M. Purugganan n

MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Base Sequence; Binding Sites; Haplotypes; MicroRNAs / genetics; MicroRNAs / metabolism; Molecular Sequence Data; Polymorphism, Single Nucleotide; Temperature
TL;DR: Both miRNAs and their target binding sites have very low nucleotide variation and divergence compared to their flanking sequences in Arabidopsis, indicating strong purifying selection on these sites in this species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Diversity and divergence patterns in regulatory genes suggest differential gene flow in recently derived species of the Hawaiian silversword alliance adaptive radiation (Asteraceae)

MOLECULAR ECOLOGY, 16(19), 3995–4013.

By: A. Lawton-Rauh*, R. Robichaux* & M. Purugganan n

author keywords: adaptive radiation; allele-sharing; gene flow; Hawaiian silversword alliance; regulatory gene evolution; speciation
MeSH headings : Adaptation, Biological; Asteraceae / anatomy & histology; Asteraceae / genetics; Base Sequence; Gene Flow; Genes, Regulator; Genetic Speciation; Haplotypes; Hawaii; Molecular Sequence Data; Sequence Alignment; Sequence Analysis, DNA; Species Specificity
TL;DR: The results suggest that adaptively radiating species can exhibit contrasting allele migration rates among loci such that allele movement at specific loci may supersede genetic divergence caused by drift and that lineage divergence during adaptive radiation can be associated with population expansion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Evolutionary patterns in the antR-Cor gene in the dwarf dogwood complex (Cornus, Cornaceae)

Genetica, 130(1), 19–34.

By: C. Fan n, Q. Xiang*, D. Remington*, M. Purugganan n & B. Wiegmann n

author keywords: Cornus; gene evolution; hybridization; Myc-like anthocyanin regulatory gene; mucleotide polymorphism; polyploid; speciation
MeSH headings : Alaska; Amino Acid Sequence; Base Sequence; British Columbia; Color; Cornus / genetics; Evolution, Molecular; Flowers / genetics; Genes, Plant; Genetic Variation; Idaho; Molecular Sequence Data; Oregon; Phylogeny; Sequence Homology, Nucleic Acid; Washington; Yukon Territory
TL;DR: Seven amino acid mutations that are potentially linked to myc-like anthocyanin regulatory gene function correlate with petal colors differences that characterize the divergence between two diploid species and the tetraploids species in this dwarf dogwood complex, providing a working hypothesis for testing the role of the gene in speciation and its link to the petal coloration. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Fitness effects associated with the major flowering time gene FRIGIDA in Arabidopsis thaliana in the field

AMERICAN NATURALIST, 169(5), E141–E157.

By: T. Korves*, K. Schmid, A. Caicedo*, C. Mays*, J. Stinchcombe, M. Purugganan*, J. Schmitt

author keywords: epistasis; FLOWERING LOCUS C (FLC); population structure; vernalization; candidate gene association; heterogeneous selection
MeSH headings : Analysis of Variance; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Epistasis, Genetic; Evolution, Molecular; Flowers / genetics; Flowers / growth & development; Genetic Variation; Genetics, Population; Genotype; MADS Domain Proteins / genetics; Rhode Island; Seasons; Selection, Genetic; Survival Analysis
TL;DR: The results suggest that the combined effects of seasonally varying selection and epistasis could explain the maintenance of variation at FRI and, more generally, may be important in the evolution of genes underlying complex traits. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Genetics of microenvironmental canalization in Arabidopsis thaliana

Proceedings of the National Academy of Sciences of the United States of America, 104(34), 13717–13722.

By: M. Hall, I. Dworkin, M. Ungerer & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

The extent of linkage disequilibrium in rice (Oryza sativa L.)

GENETICS, 177(4), 2223–2232.

By: K. Mather n, A. Caicedo n, N. Polato*, K. Olsen n, S. McCouch* & M. Purugganan n

MeSH headings : Base Sequence; Crops, Agricultural / genetics; Genetic Linkage; Genome, Plant; Linkage Disequilibrium; Molecular Sequence Data; Oryza / genetics; Polymorphism, Single Nucleotide; Recombination, Genetic
TL;DR: The feasibility of genomewide association mapping in cultivated Asian rice using a modest number of SNPs is demonstrated and variation in LD patterns among genomic regions is suggested. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

The genetic architecture of shoot branching in Arabidopsis thaliana: A comparative assessment of candidate gene associations vs. quantitative trait locus mapping

GENETICS, 176(2), 1223–1236.

By: I. Ehrenreich n, P. Stafford n & M. Purugganan*

MeSH headings : Arabidopsis / genetics; Arabidopsis Proteins / genetics; Chromosome Mapping; Gene Amplification; Genes, Plant; Genetic Variation; Linkage Disequilibrium; Molecular Sequence Data; Plant Shoots / genetics; Quantitative Trait Loci
TL;DR: The results suggest that epistasis is prevalent in determining branching variation in A. thaliana and may need to be considered in linkage disequilibrium mapping studies of genetically diverse accessions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Comparative sequencing of plant genomes: Choices to make

Plant Cell, 18(5), 1100–1104.

By: S. Jackson, S. Rounsley & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Genomic variation in rice: Genesis of highly polymorphic linkage blocks during domestication

PLOS GENETICS, 2(11), 1824–1833.

MeSH headings : Agriculture; Base Sequence; Crops, Agricultural / genetics; Genes, Plant / genetics; Genome, Plant / genetics; Haplotypes; Linkage Disequilibrium / genetics; Molecular Sequence Data; Oryza / genetics; Phylogeny; Polymorphism, Genetic; Population Dynamics; Species Specificity
TL;DR: In this hypothesis, divergent haplotypes that were adapted to different geographical and ecological environments migrated along with humans during the development of domesticated varieties would be enriched for loci that contribute to the enormous range of phenotypic variation observed among domesticated breeds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Molecular population genetics and phenotypic diversification of two populations of the thermophilic cyanobacterium Mastigocladus laminosus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(4), 2793–2800.

By: . Miller n, M. Purugganan n & S. Curtis n

MeSH headings : Cyanobacteria / classification; Cyanobacteria / genetics; Cyanobacteria / growth & development; DNA, Bacterial / analysis; Fresh Water / microbiology; Genetics, Population; Genotype; Hot Springs / microbiology; Hot Temperature; Molecular Sequence Data; Nitrogen / metabolism; Phenotype; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA
TL;DR: Investigating the distributions of genetic and phenotypic variation for two Yellowstone National Park populations of the heterocyst-forming cyanobacterium Mastigocladus (Fischerella) laminosus found that the populations are expected to continue to diverge due to low migratory gene flow. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Selection under domestication: Evidence for a sweep in the rice Waxy genomic region

GENETICS, 173(2), 975–983.

By: K. Olsen n, A. Caicedo n, N. Polato*, A. McClung, S. McCouch* & M. Purugganan n

MeSH headings : Agriculture; Amylose / metabolism; DNA, Plant / genetics; Evolution, Molecular; Genetic Variation; Genome, Plant; Mutation; Oryza / classification; Oryza / genetics; Oryza / metabolism; Plant Proteins / genetics; Selection, Genetic; Species Specificity; Starch Synthase / genetics
TL;DR: Findings demonstrate that selection pressures associated with crop domestication regimes can exceed by one to two orders of magnitude those observed for genes under even strong selection in natural systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2006 review

The molecular genetic basis of plant adaptation

[Review of ]. American Journal of Botany, 93(7), 953–962.

By: I. Ehrenreich & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Adaptive radiation and regulatory gene evolution in the Hawaiian silversword alliance (Asteraceae)

Annals of the Missouri Botanical Garden, 92(1), 28–35.

By: M. Purugganan & R. Robichaux

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Comparative plant genomics. Frontiers and prospects

Caicedo, A. L., & Purugganan, M. D. (2005, June). PLANT PHYSIOLOGY, Vol. 138, pp. 545–547.

By: A. Caicedo n & M. Purugganan n

MeSH headings : Biological Evolution; Expressed Sequence Tags; Gene Expression Profiling; Genome, Plant; Genomic Library; Genomics / trends; Phylogeny
TL;DR: The availability of whole-genome sequences as well as other genomic resources (e.g. microarray methods, expressed sequence tag [EST] libraries) and comparisons have long been the cornerstone of studies that draw inferences about function and evolution at various levels of biological organization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Evolutionary and ecological genomics of arabidopsis

PLANT PHYSIOLOGY, 138(2), 578–584.

By: K. Shimizu n & M. Purugganan n

MeSH headings : Adaptation, Physiological / genetics; Arabidopsis / genetics; Biological Evolution; Ecosystem; Gene Expression Regulation, Plant; Genetic Variation; Genomics; Selection, Genetic
TL;DR: Questions traditionally asked in the domain of ecology and evolutionary biology, and what determines the timing of flowering and germination are addressed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

High-diversity genes in the Arabidopsis genome

GENETICS, 170(4), 1897–1911.

By: J. Cork n & M. Purugganan n

MeSH headings : Alleles; Arabidopsis / genetics; Base Sequence; DNA, Plant / analysis; Genes, Plant; Genetic Linkage; Genetic Variation; Genome, Plant; Haplotypes; Kinetics; Molecular Sequence Data; Polymorphism, Genetic; Recombination, Genetic; Sequence Analysis, DNA
TL;DR: Comparison of 4300 random shotgun sequence fragments of the Arabidopsis thaliana Ler ecotype genome with the whole genomic sequence of the Col-0 ecotype identified 60 genes with putatively high levels of intraspecific variability, three of which were found to display elevated levels of nucleotide polymorphism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Molecular population genetics of redundant floral-regulatory genes in Arabidopsis thaliana

Molecular Biology and Evolution, 22(1), 91–103.

By: R. Moore, S. Grant & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2005 review

The evolutionary dynamics of plant duplicate genes

[Review of ]. CURRENT OPINION IN PLANT BIOLOGY, 8(2), 122–128.

By: R. Moore n & M. Purugganan n

MeSH headings : Evolution, Molecular; Gene Duplication; Genes, Plant; Multigene Family; Plants / genetics; Polyploidy
TL;DR: Insight is provided into the roles that gene and genome duplications play in plant evolution by combining recent advances in genomic analysis with a new conceptual framework. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

The molecular population genetics of the Tomato spotted wilt virus (TSWV) genome

MOLECULAR ECOLOGY, 14(1), 53–66.

By: M. Tsompana n, J. Abad n, M. Purugganan n & J. Moyer n

author keywords: Bunyaviridae; founder effect; mutation rate; population expansion; selection; TSWV
MeSH headings : Base Sequence; Genetics, Population; Genome, Viral; Homozygote; Solanum lycopersicum / virology; Models, Genetic; Phylogeny; Reverse Transcriptase Polymerase Chain Reaction; Tospovirus / classification; Tospovirus / genetics
TL;DR: This analysis has defined the geographical structure of TSWV, and identifies specific amino acid sites subject to selection within Bunyaviridae and estimates the level of genetic heterogeneity of a highly pathogenic plant RNA virus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Vernalization sensitivity in Arabidopsis thaliana (brassicaceae): The effects of latitude and FLC variation

AMERICAN JOURNAL OF BOTANY, 92(10), 1701–1707.

By: . Stinchcombe*, A. Caicedo n, R. Hopkins*, C. Mays n, E. Boyd*, M. Purugganan n, J. Schmitt*

author keywords: Brassicaceae; ecological genomics; FLC; flowering time; FRI; latitudinal cline; vernalization
TL;DR: A significant latitudinal cline in vernalization sensitivity was observed: southern accessions were more sensitive to vernnalization than northern accessions, and accessions that were late flowering in the absence of vernAlization were moresensitive to Vernalization cues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

A latitudinal cline in flowering time in Arabidopsis thaliana modulated by the flowering time gene FRIGIDA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(13), 4712–4717.

By: . Stinchcombe n, C. Weinig n, M. Ungerer n, K. Olsen n, C. Mays n, S. Halldorsdottir n, M. Purugganan n, J. Schmitt n

MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / physiology; Arabidopsis Proteins / genetics; Biological Clocks; Climate; Ecosystem; Flowers / genetics; Flowers / physiology; Genetic Variation; Light
TL;DR: The results suggest that the ecological function of the vernalization requirement conferred by FRI differs across latitudes, and indicate that by combining ecological and molecular genetic data, it is possible to understand the forces acting on life history transitions at the level of specific loci. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
6. Clean Water and Sanitation (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 article

Darwinian selection on a selfing locus (Retracted Article. See vol 320, pg 176, 2008)

Shimizu, K. K., Cork, J. M., Caicedo, A. L., Mays, C. A., Moore, R. C., Olsen, K. M., … Purugganan, M. D. (2004, December 17). SCIENCE, Vol. 306, pp. 2081–2084.

By: K. Shimizu n, J. Cork n, A. Caicedo n, C. Mays n, R. Moore n, K. Olsen n, S. Ruzsa n, G. Coop n ...

MeSH headings : Alleles; Arabidopsis / genetics; Arabidopsis / physiology; Biological Evolution; Chromosome Mapping; Climate; DNA, Intergenic; Genes, Plant; Genetic Variation; Genome, Plant; Geography; Haplotypes; Likelihood Functions; Molecular Sequence Data; Open Reading Frames; Phylogeny; Plant Proteins; Pollen; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protein Kinases / genetics; Protein Kinases / physiology; Pseudogenes; Recombination, Genetic; Selection, Genetic; Time
TL;DR: Coalescent simulations indicate that ancillary morphological innovations associated with self-pollination can evolve rapidly after the inactivation of the self-incompatibility response, and suggest that the post-Pleistocene expansion of A. thaliana from glacial refugia may have been associated with this adaptive event. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 article

Epialleles via DNA methylation: consequences for plant evolution

Kalisz, S., & Purugganan, M. D. (2004, June). TRENDS IN ECOLOGY & EVOLUTION, Vol. 19, pp. 309–314.

By: S. Kalisz* & M. Purugganan n

TL;DR: Recent advances in molecular genetic techniques could enable population biologists to screen for epiallelic variants within plant populations and disentangle epigenetic from more standard genetic sources of phenotypic variance, such as additive genetic variance, dominance variance, epistasis and maternal genetic effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Epistatic interaction between Arabidopsis FRI and FLC flowering time genes generates a latitudinal cline in a life history trait

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(44), 15670–15675.

By: A. Caicedo n, . Stinchcombe n, K. Olsen n, J. Schmitt n & M. Purugganan n

author keywords: rosette leaf number; alternative splicing; linkage disequilibrium; epistatic selection; candidate gene association
MeSH headings : Alternative Splicing; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Base Sequence; DNA, Plant / genetics; Epistasis, Genetic; Evolution, Molecular; Flowers / growth & development; Genes, Plant; Genetics, Population; Genotype; Haplotypes; Linkage Disequilibrium; MADS Domain Proteins / genetics; Molecular Sequence Data; Polymorphism, Single Nucleotide; Sequence Homology, Nucleic Acid; Time Factors
TL;DR: It is suggested that developmental genetic pathways and networks provide the molecular basis for epistasis, contributing to ecologically important phenotypic variation in natural populations and to the process of evolutionary diversification. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Heterogeneous evolution of the Myc-like Anthocyanin regulatory gene and its phylogenetic utility in Cornus L. (Cornaceae)

MOLECULAR PHYLOGENETICS AND EVOLUTION, 33(3), 580–594.

By: C. Fan n, M. Purugganan n, D. Thomas n, B. Wiegmann n & Q. Xiang n

author keywords: Cornus; heterogeneous evolution; myc-like anthocyanin regulatory gene; phylogenetics; positive selection
MeSH headings : Anthocyanins / genetics; Cloning, Molecular; Cornus / genetics; DNA Primers / genetics; Databases as Topic; Evolution, Molecular; Gene Deletion; Genes, Plant; Genes, myc; Models, Genetic; Mutation; Phylogeny; Polymerase Chain Reaction
TL;DR: Phylogenetic analyses demonstrate that the myc-like anthocyanin regulatory gene has potential as an informative phylogenetic marker at different taxonomic levels, depending on the data set considered (DNA or protein sequences) and regions applied (exons or introns). (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Linkage disequilibrium mapping of Arabidopsis CRY2 flowering time alleles

GENETICS, 167(3), 1361–1369.

MeSH headings : Amino Acid Sequence; Arabidopsis / genetics; Arabidopsis / physiology; Arabidopsis Proteins / genetics; Base Sequence; Cryptochromes; Flowers / physiology; Gene Components; Genetics, Population; Haplotypes / genetics; Linkage Disequilibrium; Molecular Sequence Data; Photoperiod; Phylogeny; Polymorphism, Genetic; Sequence Analysis, DNA; Time Factors
TL;DR: This study demonstrates the utility of LD mapping for elucidating the genetic basis of natural, ecologically relevant variation in Arabidopsis by examining haplotype variation in the genomic region of the photoperiod receptor CRYPTOCHROME2 and associated flowering time variation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 review

The evolution of molecular genetic pathways and networks

[Review of ]. BIOESSAYS, 26(5), 479–484.

By: J. Cork n & M. Purugganan n

MeSH headings : Animals; Evolution, Molecular; Genomics; Humans; Models, Genetic; Molecular Biology; Phenotype
TL;DR: Investigations on the relationships between network organization, topological architecture and evolutionary dynamics provide intriguing hints as to how networks evolve. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 review

The evolution of plant development

[Review of ]. AMERICAN JOURNAL OF BOTANY, 91(10), 1726–1741.

By: W. Friedman*, R. Moore n & M. Purugganan n

author keywords: apical meristem; flower; leaf; origin; plant systematics; root; shoot
TL;DR: It is concluded that it is the combination of phylogenetic studies, structural analyses of fossil and extant taxa, and molecular developmental genetic information that will lead to the greatest understanding of the evolution of plant development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 review

Candidate genes, quantitative trait loci, and functional trait evolution in plants

[Review of ]. INTERNATIONAL JOURNAL OF PLANT SCIENCES, 164(3), S7–S20.

By: D. Remington n & M. Purugganan n

author keywords: QTL; flowering time; candidate gene; adaptive evolution; regulatory genes
TL;DR: The insights into plant evolution that have been provided by molecular methods are reviewed and future research needs are addressed, indicating that plant growth variation may be directly regulated rather than primarily the indirect result of selection on constituent processes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Genotype-environment interactions at quantitative trait loci affecting inflorescence development in Arabidopsis thaliana

Genetics, 165(1), 353–365.

By: M. Ungerer, S. Halldorsdottir, M. Purugganan & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Heterogeneous selection at specific loci in natural environments in Arabidopsis thaliana

Genetics, 165(1), 321–329.

By: C. Weinig, L. Dorn, N. Kane, Z. German, S. Hahdorsdottir, M. Ungerer, Y. Toyonaga, T. Mackay, M. Purugganan, J. Schmitt

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Intron and polypeptide evolution of conserved NPA to NPA motif regions in plant aquaporins

Journal of the American Society for Horticultural Science, 128(4), 591–597.

By: J. Xie, T. Wehner, K. Wollenberg, M. Purugganan & M. Conkling

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Merging ecology, molecular evolution, and functional genetics

Purugganan, M., & Gibson, G. (2003, May). MOLECULAR ECOLOGY, Vol. 12, pp. 1109–1112.

By: M. Purugganan n & G. Gibson n

MeSH headings : Ecology; Evolution, Molecular; Genotype; Phenotype
TL;DR: While the use of molecular markers by ecologists has been fruitful, there is more to the molecules than their current dominant role in ecological research as mere genetic barcodes, and ecologists stand today at a crossroads that provide unprecedented opportunity to make connections between genes and ecological processes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Michael Purugganan

Nature, 421(6919), 117.

By: M. Purugganan n

UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Molecular population genetics of the Arabidopsis CLAVATA2 region: The genomic scale of variation and selection in a selfing species

Genetics, 163(3), 1083–1095.

By: K. Shepard & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Patterns of nucleotide variation in homoeologous regulatory genes in the allotetraploid Hawaiian silversword alliance (Asteraceae)

MOLECULAR ECOLOGY, 12(5), 1301–1313.

By: A. Lawton-Rauh n, R. Robichaux* & M. Purugganan n

author keywords: adaptive radiation; allopolyploidy; floral homeotic genes; gene duplication; MADS-box; polyploidy
MeSH headings : Asteraceae / genetics; Base Sequence; Chromosome Mapping; DNA Primers; Evolution, Molecular; Genes, Duplicate / genetics; Genes, Homeobox / genetics; Genetic Variation; Haplotypes; Molecular Sequence Data; Phylogeny; Polyploidy
TL;DR: Results suggest that differing evolutionary forces can affect duplicate loci arising from allopolyploidization, which is prevalent in a large number of eukaryotic organisms and is particularly widespread in flowering plants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Selection on rapidly evolving proteins in the Arabidopsis genome

Genetics, 163(2), 723–733.

By: M. Barrier, C. Bustamante, J. Yu & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

The early stages of duplicate gene evolution

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(26), 15682–15687.

By: R. Moore n & M. Purugganan n

MeSH headings : Arabidopsis / genetics; Databases, Nucleic Acid; Evolution, Molecular; Flowers; Gene Duplication; Genes, Plant / genetics; Genetic Variation; Genome, Plant; Molecular Sequence Data; RNA, Plant / genetics; RNA, Plant / isolation & purification; Time
TL;DR: Analysis of recently duplicated genes in the Arabidopsis thaliana genome reveals significantly reduced species-wide levels of nucleotide polymorphisms in the progenitor and/or duplicate gene copies, suggesting that selective sweeps accompany the initial stages of the evolution of these duplicated gene pairs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Contrasting evolutionary forces in the Arabidopsis thaliana floral developmental pathway

Genetics, 160(4), 1641–1650.

By: K. Olsen, A. Womack, A. Garrett, J. Suddith & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

GAI homologues in the Hawaiian silversword alliance (Asteraceae-Madiinae): Molecular evolution of growth regulators in a rapidly diversifying plant lineage

MOLECULAR BIOLOGY AND EVOLUTION, 19(9), 1563–1574.

By: D. Remington n & M. Purugganan*

author keywords: Madiinae; silversword alliance; GAI; adaptive radiation; selection; regulatory genes
MeSH headings : Arabidopsis Proteins / genetics; Asteraceae / classification; Asteraceae / genetics; Base Sequence; Codon / genetics; Conserved Sequence / genetics; Evolution, Molecular; Genes, Duplicate / genetics; Genes, Plant / genetics; Hawaii; North America; Phylogeny; Plant Growth Regulators / genetics; Plant Proteins / genetics; Selection, Genetic; Sequence Alignment; Species Specificity
TL;DR: This work isolated genes in the DELLA subfamily of putative growth regulators from 13 taxa of Hawaiian and North American Madiinae, consistent with an allotetraploid origin for the silversword alliance and failed to detect evidence for positive selection on individual codons. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 article

Linking molecular insight and ecological research

Jackson, R. B., Linder, C. R., Lynch, M., Purugganan, M., Somerville, S., & Thayer, S. S. (2002, September). TRENDS IN ECOLOGY & EVOLUTION, Vol. 17, pp. 409–414.

By: R. Jackson*, C. Linder*, M. Lynch*, M. Purugganan n, S. Somerville* & S. Thayer*

TL;DR: Combining genomic and ecological research perspectives will answer crucial unresolved questions, but will require significant new multidisciplinary resources, infrastructure and training. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Molecular evidence on the origin and evolution of glutinous rice

Genetics, 162(2), 941–950.

By: K. Olsen & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Novel loci control variation in reproductive timing in Arabidopsis thaliana in natural environments

Genetics, 162(4), 1875–1884.

By: C. Weinig, M. Ungerer, L. Dorn, N. Kane, Y. Toyonaga, S. Halldorsdottir, T. Mackay, M. Purugganan, J. Schmitt

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Quantitative trait loci for inflorescence development in Arabidopsis thaliana

Genetics, 160(3), 1133–1151.

By: M. Ungerer, S. Halldorsdottir, J. Modliszewski, T. Mackay & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

The cost of inbreeding in Arabidopsis

NATURE, 416(6880), 531–534.

MeSH headings : Amino Acid Substitution; Animals; Arabidopsis / genetics; Arabidopsis / physiology; Biological Evolution; Drosophila / genetics; Genes, Plant; Inbreeding; Models, Genetic; Polymorphism, Genetic; Selection, Genetic
TL;DR: In a comparison of amino-acid replacements amongspecies of the mustard weed Arabidopsis with those among species of the fruitfly Drosophila, it is found that there is evidence for predominantly beneficial gene substitutions but predominantly detrimental substitutions inArabidopsis, corroborating a prediction of population genetics theory that species with a high frequency of inbreeding are less efficient in eliminating deleterious mutations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 review

The genetics of plant morphological evolution

[Review of ]. CURRENT OPINION IN PLANT BIOLOGY, 5(1), 49–55.

By: K. Shepard n & M. Purugganan n

MeSH headings : ATP-Binding Cassette Transporters / genetics; ATP-Binding Cassette Transporters / physiology; Adaptation, Physiological; Bacterial Proteins / genetics; Bacterial Proteins / physiology; Biological Evolution; Cycadopsida / genetics; Cycadopsida / growth & development; Gene Expression Regulation, Plant; MADS Domain Proteins / genetics; MADS Domain Proteins / physiology; Magnoliopsida / genetics; Magnoliopsida / growth & development; Plant Proteins / genetics; Plant Proteins / physiology; Plant Structures / genetics; Plant Structures / growth & development; Reproduction; Transcription Factors / genetics; Transcription Factors / physiology
TL;DR: Candidate gene and mapping analyses of floral symmetry, sex determination, inflorescence architecture, and compound leaves provide intriguing glimpses into the evolution of morphological adaptations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Accelerated regulatory gene evolution in an adaptive radiation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98(18), 10208–10213.

By: M. Barrier n, R. Robichaux n & M. Purugganan n

author keywords: floral regulatory loci; MADS-box; CAB9; Hawaiian silversword alliance
MeSH headings : Adaptation, Physiological / genetics; Arabidopsis / genetics; Asteraceae / genetics; Base Sequence; Chromosome Mapping; DNA Primers / genetics; Evolution, Molecular; Gene Expression Regulation, Plant; Genes, Plant; Genes, Regulator; Hawaii; Molecular Sequence Data; Mutation; North America; Plants / genetics
TL;DR: Comparisons of rates of regulatory and structural gene evolution in the Hawaiian species to those in related species of North American tarweeds suggest that accelerated rates of Regulatory gene evolution may accompany rapid morphological diversification within adaptive radiations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Map-based cloning of quantitative trait loci: progress and prospects

Genetical Research, 78(3), 213–218.

By: D. Remington, M. Ungerer & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Interspecific evolution in plant microsatellite structure

GENE, 241(1), 101–105.

By: M. Barrier n, E. Friar*, R. Robichaux* & M. Purugganan n

author keywords: adaptive radiation; floral regulatory genes; Hawaiian silversword alliance; imperfect microsatellites; simple sequence repeats
MeSH headings : Carrier Proteins / genetics; Evolution, Molecular; Genes, Plant; Microsatellite Repeats; Models, Genetic; Phylogeny
TL;DR: Several intragenically linked microsatellites have been identified in the floral regulatory genes A. sandwicense APETALA1 and ASAP1, suggesting that they are hotspots for microsatellite formation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2000 review

Molecular evolution of flower development

[Review of ]. TRENDS IN ECOLOGY & EVOLUTION, 15(4), 144–149.

By: A. Lawton-Rauh, E. Alvarez-Buylla & M. Purugganan*

TL;DR: The study of the evolution of genes that control floral morphogenesis permits us to draw inferences on the diversification of developmental systems, the origin of floral organs and the selective forces that drive evolutionary change among these plant reproductive structures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Quantitative trait loci for floral morphology in Arabidopsis thaliana

Genetics, 156(3), 1379–1392.

By: T. Juenger, M. Purugganan & T. MacKay

Source: NC State University Libraries
Added: August 6, 2018

2000 review

The molecular population genetics of regulatory genes

[Review of ]. MOLECULAR ECOLOGY, 9(10), 1451–1461.

By: M. Purugganan n

author keywords: evolution of development; phenotypic variation; polymorphism; promoters; QTL; transcriptional activators
MeSH headings : Adaptation, Physiological / genetics; Animals; Evolution, Molecular; Genes, Regulator; Genetic Variation; Genetics, Population; Plants / genetics; Promoter Regions, Genetic; Selection, Genetic
TL;DR: These recent analyses suggest that it may be possible to study the molecular evolutionary ecology of regulatory diversification by examining both the extent and patterning of regulatory gene diversity, the phenotypic effects of molecular variation at these loci and their ecological consequences. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Variation and selection at the CAULIFLOWER floral homeotic gene accompanying the evolution of domesticated Brassica oleracea

Genetics, 155(2), 855–862.

By: M. Purugganan, A. Boyles & J. Suddith

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Duplication of the Brassica oleracea APETALA1 floral homeotic gene and the evolution of domesticated cauliflower

Journal of Heredity, 90(5), 514–520.

By: A. Lowman & M. Purugganan

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Interspecific hybrid ancestry of a plant adaptive radiation: Allopolyploidy of the Hawaiian silversword alliance (Asteraceae) inferred from floral homeotic gene duplications

MOLECULAR BIOLOGY AND EVOLUTION, 16(8), 1105–1113.

By: M. Barrier n, B. Baldwin n, R. Robichaux n & M. Purugganan n

author keywords: MADS-box; inflorescence
MeSH headings : Adaptation, Physiological; Amino Acid Sequence; Arabidopsis Proteins; Asteraceae / genetics; Asteraceae / radiation effects; Chimera / genetics; Evolution, Molecular; Founder Effect; Gene Dosage; Gene Duplication; Hawaii; Homeodomain Proteins / genetics; MADS Domain Proteins; Molecular Sequence Data; North America; Phylogeny; Plant Proteins / genetics; Polymerase Chain Reaction; Polyploidy; Species Specificity
TL;DR: It is determined that two floral homeotic genes, ASAP3/TM6 and ASAP1, are found in duplicate copies within members of the Hawaiian silversword alliance and appear to have arisen as a result of interspecific hybridization between two North American tarweed species. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Molecular population genetics of floral homeotic loci: departures from the equilibrium-neutral model at the APETALA3 and PISTILLATA genes of Arabidopsis thaliana

Genetics, 151(2), 839–848.

By: M. Purugganan & J. Suddith

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Patterns of molecular evolution among paralogous floral homeotic genes

MOLECULAR BIOLOGY AND EVOLUTION, 16(8), 1037–1045.

By: A. Lawton-Rauh n, E. Buckler n & M. Purugganan n

author keywords: Arabidopsis thaliana; Arabidopsis lyrata; MADS-box; APETALA1; APETALA3; CAULIFLOWER; PISTILLATA
MeSH headings : Arabidopsis / genetics; Arabidopsis Proteins; DNA-Binding Proteins / genetics; Evolution, Molecular; Gene Expression Regulation, Plant; Genes, Homeobox / genetics; Genes, Plant; Genetic Variation; Homeodomain Proteins / genetics; MADS Domain Proteins; Molecular Sequence Data; Plant Proteins / genetics; Plant Structures / genetics; Transcription Factors / genetics
TL;DR: Analysis of orthologs to the Arabidopsis thaliana MADS-box floral meristem genes APETALA1 and CAULIFLOWER and the floral organ identity genes APetALA3 and PISTILLATA reveal contrasting dynamics of molecular evolution between these paralogous floral regulatory genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Molecular population genetics of the Arabidopsis CAULIFLOWER regulatory gene: Nonneutral evolution and naturally occurring variation in floral homeotic function

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 95(14), 8130–8134.

By: M. Purugganan n & J. Suddith n

author keywords: development; ecotype; flower; inflorescence; MADS-box
MeSH headings : Arabidopsis / genetics; Arabidopsis Proteins; Base Sequence; DNA-Binding Proteins / genetics; Evolution, Molecular; Genetic Variation; Genetics, Population; MADS Domain Proteins; Molecular Sequence Data; Plant Proteins / genetics
TL;DR: Molecular analyses of naturally occurring alleles of the Arabidopsis thaliana CAULIFLOWER locus reveal considerable intraspecific diversity at this floral homeotic gene, and the McDonald-Kreitman test suggests that this gene is evolving in a nonneutral fashion, with an excess of intrasPEcific replacement polymorphisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1998 review

The molecular evolution of development

[Review of ]. BIOESSAYS, 20(9), 700–711.

By: M. Purugganan n

TL;DR: Molecular evolutionary genetics provides one of several approaches to dissecting the evolution of developmental systems, by allowing us to reconstruct the history of developmental genetic pathways, infer the origin and diversification of developmental gene functions, and assess the relative contributions of various evolutionary forces in shaping regulatory gene evolution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

The MADS-box floral homeotic gene lineages predate the origin of seed plants: Phylogenetic and molecular clock estimates

JOURNAL OF MOLECULAR EVOLUTION, 45(4), 392–396.

By: M. Purugganan n

author keywords: floral homeotic genes; flowers; development; evolution; MADS-box
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Evolution, Molecular; Genes, Homeobox; Genes, Plant; Phylogeny; Plant Development; Plants / genetics; Species Specificity; Time Factors
TL;DR: The evolutionary history of these developmental genes was reconstructed using 74 loci from 15 dicot, three monocot, and one conifer species to suggest that the different floral homeotic gene lineages began to diverge from one another about 450–500 mya, around the time of the origin of land plants themselves. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

The evolution of the conserved ATPase domain (CAD): Reconstructing the history of an ancient protein module

JOURNAL OF MOLECULAR EVOLUTION, 45(5), 549–563.

By: J. Swaffield n & M. Purugganan n

author keywords: AAA proteins; ATPase; proteasome; NSF; Sec; Pas; metalloprotease
MeSH headings : Adenosine Triphosphatases / classification; Adenosine Triphosphatases / metabolism; Adenosine Triphosphatases / physiology; Archaea / genetics; Bacteria / genetics; Cysteine Endopeptidases / metabolism; Cytoskeletal Proteins / metabolism; Cytoskeletal Proteins / physiology; Eukaryotic Cells / physiology; Evolution, Molecular; Membrane Proteins / metabolism; Membrane Proteins / physiology; Metalloendopeptidases / metabolism; Metalloendopeptidases / physiology; Multienzyme Complexes / metabolism; Phylogeny; Proteasome Endopeptidase Complex
TL;DR: The phylogeny of the CADs provides the basis for establishing the patterns of evolutionary change that characterize the AAA proteins. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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