Megan Jolane Burke

Works (11)

Updated: February 6th, 2025 07:50

2024 journal article

Hemadsorption extracorporeal therapy removes cytokines ex vivo in horses

AMERICAN JOURNAL OF VETERINARY RESEARCH, 85(6).

By: K. Hobbs n , J. Davis*, B. Cooper n, Y. Ueda n , M. Burke n  & K. Sheats n 

author keywords: extracorporeal; equine; hemadsorption; cytokines; dialysis
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2024

2023 journal article

Retrospective analysis of postoperative complications following surgical treatment of ileal impaction in horses managed with manual decompression compared to jejunal enterotomy

FRONTIERS IN VETERINARY SCIENCE, 10.

By: J. Ruff n, S. Zetterstrom*, L. Boone *, E. Hofmeister *, C. Smith *, K. Epstein *, A. Blikslager n , C. Fogle n , M. Burke n 

author keywords: colic; ileum; impaction; enterotomy; manual decompression
TL;DR: It was showed that there were no significant differences in post-operative complications and survival to discharge in horses undergoing distal jejunal enterotomy versus manual decompression for correction of ileal impaction, and pre-operative PCV and duration of surgery were found to be the only predictive factors of survival to discharged. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 22, 2023

2023 article

Severe unilateral nephrolithiasis and recurrent colic in a horse

Murillo, D. F. B., Ramaker, E., Burke, M., Walker, R., & Negrao Watanabe, T. T. (2023, January 12). VETERINARY RECORD CASE REPORTS, Vol. 1.

By: D. Murillo *, E. Ramaker n, M. Burke n , R. Walker n & T. Negrao Watanabe n

author keywords: horses; internal medicine; kidneys; pathology; urinary tract; urology
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 30, 2023

2021 journal article

Development and Formative Evaluation of a Low-Fidelity Equine Castration Model for Veterinary Education

FRONTIERS IN VETERINARY SCIENCE, 8.

By: M. Sheats  n, M. Burke n , J. Robertson n , K. Fiebrandt n & C. Fogle n 

author keywords: competency; veterinary education; veterinary simulators; surgical simulation and training; model development and evaluation; equine castration model; horse castration model
TL;DR: This work developed an inexpensive, low-fidelity model of equine field castration and evaluated it using a mixed-methods approach, suggesting that both students and veterinary educators feel that this low- fidelity model has educational value. (via Semantic Scholar)
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4. Quality Education (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 12, 2021

2019 journal article

Letter to the Editor: Bias in statistics or bias in equine veterinary medicine?

Equine Veterinary Journal, 51(3), 423–423.

By: A. Ziegler n , C. Fogle n , M. Burke n  & A. Blikslager n 

MeSH headings : 4-Butyrolactone / analogs & derivatives; Animals; Clonixin / analogs & derivatives; Horses; Sulfones
TL;DR: It is proposed that validating a trend towards improved survival in horses treated with firocoxib would require additional studies with greater numbers of horses and likely modification of the study design to include preoperative drug randomisation. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: May 6, 2019

2018 journal article

Advances in Diagnostics and Treatments in Horses with Acute Colic and Postoperative Ileus

Veterinary Clinics of North America: Equine Practice, 34(1), 81–96.

By: M. Burke n  & A. Blikslager n 

author keywords: Acute colic; Novel diagnostic biomarkers; Systemic inflammatory response syndrome (SIRS); Pain and motility management
MeSH headings : Acute Disease; Animals; Colic / diagnosis; Colic / surgery; Colic / therapy; Colic / veterinary; Horse Diseases / diagnosis; Horse Diseases / surgery; Horse Diseases / therapy; Horses; Ileus; Postoperative Complications / etiology; Postoperative Complications / veterinary
TL;DR: Investigation of novel biomarkers, which may help to differentiate surgical lesions from those that can be managed medically, continues to be an active area of research. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Evaluation of digital cryotherapy using a commercially available sleeve style ice boot in healthy horses and horses receiving i.v. endotoxin

EQUINE VETERINARY JOURNAL, 50(6), 848–853.

By: M. Burke n , J. Tomlinson *, A. Blikslager n , A. Johnson * & B. Dallap-Schaer*

author keywords: horse; digital cryotherapy; sepsis-associated laminitis; sleeve-style ice boot; lamellar temperatures
MeSH headings : Animals; Cross-Over Studies; Cryotherapy / instrumentation; Cryotherapy / standards; Cryotherapy / veterinary; Endotoxins / administration & dosage; Endotoxins / blood; Female; Foot Diseases / therapy; Foot Diseases / veterinary; Forelimb; Hoof and Claw / pathology; Horse Diseases / therapy; Horses; Male; Prospective Studies; Random Allocation; Skin Temperature
TL;DR: This study is the first to show that a sleeve style boot, where ice does not cover the hoof, can cause significant decreases in lamellar temperatures through cooling of blood as it travels to the foot. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018

2018 journal article

Multicentre, blinded, randomised clinical trial comparing the use of flunixin meglumine with firocoxib in horses with small intestinal strangulating obstruction

Equine Veterinary Journal, 51(3), 329–335.

By: A. Ziegler n , C. Freeman n, C. Fogle n , M. Burke n , J. Davis *, V. Cook*, L. Southwood *, A. Blikslager n 

author keywords: horse; colic; endotoxaemia; flunixin meglumine; firocoxib; clinical study
MeSH headings : 4-Butyrolactone / administration & dosage; 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / therapeutic use; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / therapeutic use; Female; Horse Diseases / drug therapy; Horses; Intestinal Obstruction / complications; Intestinal Obstruction / veterinary; Male; Pain, Postoperative / drug therapy; Pain, Postoperative / veterinary; Random Allocation; Sulfones / administration & dosage; Sulfones / therapeutic use
TL;DR: Treatment of post-surgical SISO horses with firocoxib (COX-2 selective) would reduce the signs of endotoxaemia to a greater extent than flunixin meglumine (nonselective COX inhibitor) while continuing to provide similar levels of pain control. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: May 6, 2019

2017 journal article

Evaluation of the analgesic and pharmacokinetic properties of transdermally administered fentanyl in goats.

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001).

By: M. Burke* , L. Soma *, R. Boston*, J. Rudy* & T. Schaer *

MeSH headings : Administration, Cutaneous; Analgesics, Opioid / administration & dosage; Analgesics, Opioid / pharmacokinetics; Analgesics, Opioid / pharmacology; Animals; Female; Fentanyl / administration & dosage; Fentanyl / pharmacokinetics; Fentanyl / pharmacology; Goat Diseases / drug therapy; Goats; Pain, Postoperative / drug therapy; Pain, Postoperative / veterinary; Prospective Studies
TL;DR: Ease of administration, duration of analgesia, and decreased dosing frequency make TFPs an attractive option for pain management in goats and resulted in consistent FEN absorption and plasma concentrations within the human and ovine therapeutic ranges. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: March 16, 2023

2016 journal article

Prosthetic Mesh for Obliteration of the Nephrosplenic Space in Horses: 26 Clinical Cases

VETERINARY SURGERY, 45(2), 201–207.

By: M. Burke*  & E. Parente *

MeSH headings : Animals; Colic / surgery; Colic / veterinary; Colonic Pseudo-Obstruction / surgery; Colonic Pseudo-Obstruction / veterinary; Female; Horse Diseases / surgery; Horses; Laparoscopy / veterinary; Laparotomy / veterinary; Male; Posture; Recurrence; Retrospective Studies; Surgical Mesh / veterinary; Treatment Outcome
TL;DR: Mesh obliteration of the nephrosplenic space is an effective alternative to suture closure for preventing nephosplenic entrapment of the large colon in horses. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Colic in equine neonates: 137 cases (2000-2010).

Journal of the American Veterinary Medical Association.

By: M. Mackinnon*, L. Southwood, M. Burke*  & J. Palmer

MeSH headings : Animals; Animals, Newborn; Colic / mortality; Colic / pathology; Colic / therapy; Colic / veterinary; Enterocolitis / complications; Enterocolitis / therapy; Enterocolitis / veterinary; Female; Horse Diseases / etiology; Horse Diseases / mortality; Horse Diseases / pathology; Horse Diseases / therapy; Horses; Intestinal Obstruction; Male; Meconium; Retrospective Studies
TL;DR: Most neonates examined for signs of colic can be managed medically, and short-term survival rate in medically and surgically treated neonates was good, and long- term survival rate of foals discharged from the hospital was excellent, with most achieving intended use. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: March 16, 2023

Employment

Updated: February 6th, 2025 07:47

2018 - present

North Carolina State University Raleigh, NC, US
Associate Clinical Professor of Equine Emergency Department of Clinical Sciences

Education

Updated: March 15th, 2023 14:04

2006 - 2010

University of California, Davis CA, CA, US
DVM School of Veterinary Medicine

1998 - 2002

Brown University RI, RI, US
BA

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