Maggie Cummings

College of Agriculture and Life Sciences

Works (4)

Updated: April 5th, 2024 14:40

2023 article

Adrenomedullin: A Novel Peptide Hormone for Uterine Receptivity and Conceptus Elongation in Pigs?

Paudel, S., Liu, B., Cummings, M. J., & Wang, X. (2023, May). JOURNAL OF ANIMAL SCIENCE, Vol. 101.

By: S. Paudel n, B. Liu n, M. Cummings n & X. Wang n

author keywords: conceptuses; implantation; pregnancy
TL;DR: A significant role for ADM is indicated in uterine receptivity for implantation and conceptus growth and development in pigs, and a framework for future studies of ADM signaling to affect proliferation and migration of Tr cells, spacing of blastocysts, implantations and placentation in pigs is provided. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: March 4, 2024

2022 journal article

Prioritize biologically relevant ions for data-independent acquisition (BRI-DIA) in LC-MS/MS-based lipidomics analysis

METABOLOMICS, 18(8).

By: L. Duan n, G. Scheidemantle n, M. Lodge n, M. Cummings n, E. Pham n, X. Wang n, A. Kennedy n, X. Liu n

MeSH headings : Animals; Cardiolipins; Chromatography, Liquid / methods; Ions; Lipidomics; Metabolomics; Mice; Reproducibility of Results; Tandem Mass Spectrometry / methods
TL;DR: A novel workflow using biologically relevant lipids to construct inclusion list for data-independent acquisition (DIA), named as BRI-DIA workflow, which is as efficient as traditional DDA method in profiling lipids, but offers better consistency of lipid identification, compared to D DA method. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: July 26, 2022

2022 journal article

Uterine-specific SIRT1 deficiency confers premature uterine aging and impairs invasion and spacing of blastocyst, and stromal cell decidualization, in mice

MOLECULAR HUMAN REPRODUCTION, 28(7).

By: M. Cummings n, H. Yu*, S. Paudel n, G. Hu*, X. Li*, M. Hemberger*, X. Wang n

author keywords: SIRT1; implantation; stromal cell decidualization; pregnancy; Sirtuin 1; progesterone receptor signaling
MeSH headings : Aging; Animals; Blastocyst; Decidua / metabolism; Embryo Implantation / physiology; Female; Hedgehog Proteins / metabolism; Mice; Pregnancy; Sirtuin 1 / genetics; Sirtuin 1 / metabolism; Stromal Cells / metabolism; Uterus / metabolism
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID
Added: July 11, 2022

2021 journal article

Temporal and spatial expression of adrenomedullin and its receptors in the porcine uterus and peri-implantation conceptuses

BIOLOGY OF REPRODUCTION, 105(4), 876–891.

By: S. Paudel n, B. Liu n, M. Cummings n, K. Quinn*, F. Bazer*, K. Caron*, X. Wang n

author keywords: adrenomedullin; conceptus; uterine fluid; uterus; pigs
MeSH headings : Adrenomedullin / genetics; Adrenomedullin / metabolism; Animals; Embryo, Mammalian / metabolism; Female; Receptors, Adrenomedullin / genetics; Receptors, Adrenomedullin / immunology; Spatio-Temporal Analysis; Sus scrofa / embryology; Sus scrofa / genetics; Uterus / metabolism
TL;DR: It is suggested that adrenomedullin plays a significant role in uterine receptivity and conceptus growth and development, via the stimulation of cell proliferation and activation of MTORC1 signaling pathway in the porcine conceptus trophectoderm. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: November 15, 2021

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