Mukund Khanwalker

College of Engineering

Works (3)

Updated: April 6th, 2024 05:02

2024 article

Development of an electrochemical impedance spectroscopy immunosensor for insulin monitoring employing pyrroloquinoline quinone as an ingestible redox probe

Khanwalker, M., Hatada, M., LaBelle, J. T., & Sode, K. (2024, January 18). Biosensors and Bioelectronics, Vol. 250.

By: M. Khanwalker n, M. Hatada n, J. LaBelle* & K. Sode n 

author keywords: Electrochemical impedance spectroscopy; Pyrroloquinoline quinone; Redox probe; Insulin; In -vivo
MeSH headings : PQQ Cofactor; Biosensing Techniques / methods; Insulin; Dielectric Spectroscopy; Immunoassay; Oxidation-Reduction; Electrodes
topics (OpenAlex): Electrochemical sensors and biosensors; Analytical Chemistry and Sensors; Electrochemical Analysis and Applications
TL;DR: This study adopted a unique approach, focusing on the use of ingestible materials, by exploring naturally occurring substances within the body, with a specific emphasis on pyrroloquinoline quinone (PQQ), offering a pathway for potential in vivo applications by combining PQQ as a redox probe with EIS measurements. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 28, 2024

2022 article

Development of an electrochemical impedance spectroscopy based biosensor for detection of ubiquitin C-Terminal hydrolase L1

Lee, J., Kane, B. J., Khanwalker, M., & Sode, K. (2022, March 29). Biosensors and Bioelectronics, Vol. 208, p. 114232.

By: J. Lee  n, B. Kane n, M. Khanwalker n & K. Sode n 

author keywords: Traumatic brain injury; Ubiquitin C-Terminal hydrolase L1 (UCH-L1); Electrochemical impedance spectroscopy; Point-of-care testing; Immunosensor
MeSH headings : Biomarkers; Biosensing Techniques; Brain Injuries, Traumatic / diagnosis; Dielectric Spectroscopy; Humans; Ubiquitin Thiolesterase
topics (OpenAlex): Neonatal Respiratory Health Research; Mass Spectrometry Techniques and Applications; Advanced biosensing and bioanalysis techniques
TL;DR: This system could detect UCH-L1 within 5 min, without a washing step nor bound/free separation, and had resolution across concentrations ranging from 1 pM to 1000 pM within an artificial serum sample, which makes this platform an attractive candidate for scale-up as a device for rapid, on-site detection of TBI. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 30, 2022

2021 article

Development of an Interdigitated Electrode-Based Disposable Enzyme Sensor Strip for Glycated Albumin Measurement

Hatada, M., Loew, N., Okuda-Shimazaki, J., Khanwalker, M., Tsugawa, W., Mulchandani, A., & Sode, K. (2021, January 31). Molecules, Vol. 26.

By: M. Hatada n, N. Loew  n, J. Okuda-Shimazaki  n, M. Khanwalker n, W. Tsugawa *, A. Mulchandani *, K. Sode n 

author keywords: interdigitated electrode; glycated albumin; fructosyl amino acid oxidase; point of care testing; disposable enzyme sensor; diabetes mellitus
MeSH headings : Biosensing Techniques / instrumentation; Disposable Equipment; Electrodes; Enzymes / metabolism; Glycation End Products, Advanced; Reproducibility of Results; Serum Albumin / analysis; Glycated Serum Albumin
topics (OpenAlex): Electrochemical sensors and biosensors; Analytical Chemistry and Sensors; Biosensors and Analytical Detection
TL;DR: It is demonstrated that the application of an IDE will realize the development of highly sensitive disposable-type amperometric enzyme sensors with high reproducibility. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: March 1, 2021

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