Megha Gongireddy

College of Engineering

Works (1)

Updated: April 23rd, 2025 23:25

2023 article

Unidirectional trans-cleaving behavior of CRISPR-Cas12a unlocks for an ultrasensitive assay using hybrid DNA reporters containing a 3′ toehold

Mohammad, N., Talton, L., Hetzler, Z., Gongireddy, M., & Wei, Q. (2023, August 31). Nucleic Acids Research, Vol. 8.

By: N. Mohammad n , L. Talton n, Z. Hetzler n, M. Gongireddy n & Q. Wei n 

topics (OpenAlex): CRISPR and Genetic Engineering; Advanced biosensing and bioanalysis techniques; RNA Interference and Gene Delivery
TL;DR: This study not only unfolded new insight into the trans-cleavage behavior of Cas12a but also demonstrated a sensitive CRISPR-Cas12a assay by using a hybrid dsDNA reporter molecule. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 18, 2023

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