Mike Sano
Biophysics, Cancer Therapy, Early Cancer Detection, Electroporation, Dielectrophoresis, Microfluidics
Works (55)
2025 journal article
Dose is a Critical Factor Affecting Treatment Volumes for Integrated Nanosecond Pulse Irreversible Electroporation (INSPIRE)
IEEE Transactions on Biomedical Engineering, 1–11.
2025 journal article
High-Throughput Capable Three-Dimensional Tissue Model for Quantification of Electroporation Thresholds
Journal of Visualized Experiments, 8(222).
2025 article
Impact of Voltage on the Production on Spherical Ablations for Integrated Time Nanosecond Pulse Irreversible Electroporation
Williamson, R. H., Fong, J. A., Darrow, J., Reeg, L., Nelson, N., Iuga, A., … Sano, M. B. (2025, September 22). Bioelectricity, Vol. 9.
2025 journal article
Integrated Nanosecond Pulse Irreversible Electroporation (INSPIRE): Impact of Exposed Electrode Length on Ablation Geometry in an In Vivo Liver Model
Cancers, 17(17), 2891.
2025 journal article
Optimization of Bipolar Microsecond Electric Pulses for DNA Vaccine Delivery
IEEE Transactions on Biomedical Engineering, 1–12.
2024 journal article
A novel in vitro model of clinical cryoablation to investigate the transition zone for focal tumor ablation
Cryobiology, 114, 104844.
2024 journal article
Investigation of integrated time nanosecond pulse irreversible electroporation against spontaneous equine melanoma
Frontiers in Veterinary Science, 11.
2024 journal article
Treatment of Spontaneous Tumors With Algorithmically Controlled Electroporation
IEEE Transactions on Biomedical Engineering, 71(10), 2814–2822.
2023 journal article
Integrated Time Nanosecond Pulse Irreversible Electroporation (INSPIRE): Assessment of Dose, Temperature, and Voltage on Experimental and Clinical Treatment Outcomes
IEEE Transactions on Biomedical Engineering, 71(5), 1511–1520.
2022 journal article
Polymer Nanoparticles Enhance Irreversible Electroporation In Vitro
IEEE Transactions on Biomedical Engineering, 69(7), 2353–2362.
2020 journal article
Algorithmically Controlled Electroporation: A Technique for Closed Loop Temperature Regulated Pulsed Electric Field Cancer Ablation
IEEE Transactions on Biomedical Engineering, 67(8), 2176–2186.
2020 journal article
Electro-Thermal Therapy Algorithms and Active Internal Electrode Cooling Reduce Thermal Injury in High Frequency Pulsed Electric Field Cancer Therapies
Annals of Biomedical Engineering, 49(1), 191–202.
2020 journal article
Electro-thermal therapy: Microsecond duration pulsed electric field tissue ablation with dynamic temperature control algorithms
Computers in Biology and Medicine, 121, 103807.
2020 journal article
Irreversible electroporation is a thermally mediated ablation modality for pulses on the order of one microsecond
Bioelectrochemistry, 135, 107544.
2020 journal article
Temperature Dependence of High Frequency Irreversible Electroporation Evaluated in a 3D Tumor Model
Annals of Biomedical Engineering, 48(8), 2233–2246.
2020 journal article
Thermochromic Tissue Phantoms for Evaluating Temperature Distribution in Simulated Clinical Applications of Pulsed Electric Field Therapies
Bioelectricity, 2(4), 362–371.
2019 journal article
High-Frequency Irreversible Electroporation Using 5,000-V Waveforms to Create Reproducible 2- and 4-cm Ablation Zones—A Laboratory Investigation Using Mechanically Perfused Liver
Journal of Vascular and Interventional Radiology, 31(1), 162–168.e7.
2019 journal article
Simplified Non-Thermal Tissue Ablation With A Single Insertion Device Enabled By Bipolar High-Frequency Pulses
IEEE Transactions on Biomedical Engineering, 1–1.
2018 journal article
Burst and continuous high frequency irreversible electroporation protocols evaluated in a 3D tumor model
Physics in Medicine & Biology, 63(13), 135022.
2018 journal article
Optimization of a single insertion electrode array for the creation of clinically relevant ablations using high-frequency irreversible electroporation
Computers in Biology and Medicine, 95, 107–117.
2018 journal article
Reduction of Muscle Contractions during Irreversible Electroporation Therapy Using High-Frequency Bursts of Alternating Polarity Pulses: A Laboratory Investigation in an Ex Vivo Swine Model
Journal of Vascular and Interventional Radiology, 29(6), 893–898.e4.
2018 journal article
Synergistically Enhancing the Therapeutic Effect of Radiation Therapy with Radiation Activatable and Reactive Oxygen Species-Releasing Nanostructures
ACS Nano, 12(5), 4946–4958.
2017 journal article
A Comprehensive Characterization of Parameters Affecting High-Frequency Irreversible Electroporation Lesions
Annals of Biomedical Engineering, 45(11), 2524–2534.
2017 journal article
Asymmetric Waveforms Decrease Lethal Thresholds in High Frequency Irreversible Electroporation Therapies
Scientific Reports, 7(1).
2017 journal article
Irreversible electroporation for the ablation of pancreatic malignancies: A patient‐specific methodology
Journal of Surgical Oncology, 115(6), 711–717.
2017 journal article
Treatment of Cancer In Vitro Using Radiation and High-Frequency Bursts of Submicrosecond Electrical Pulses
IEEE Transactions on Biomedical Engineering, 65(4), 928–935.
2016 journal article
Production of Spherical Ablations Using Nonthermal Irreversible Electroporation: A Laboratory Investigation Using a Single Electrode and Grounding Pad
Journal of Vascular and Interventional Radiology, 27(9), 1432–1440.e3.
2015 journal article
Bursts of Bipolar Microsecond Pulses Inhibit Tumor Growth
Scientific Reports, 5(1), 14999.
2015 journal article
Targeted cellular ablation based on the morphology of malignant cells
Scientific Reports, 5(1), 17157.
2014 journal article
Focal blood-brain-barrier disruption with high-frequency pulsed electric fields
TECHNOLOGY, 02(03), 206–213.
2014 journal article
Focal blood-brain-barrier disruption with high-frequency pulsed electric fields
TECHNOLOGY, 2(03), 206–213.
2014 journal article
In-vitro bipolar nano- and microsecond electro-pulse bursts for irreversible electroporation therapies
Bioelectrochemistry, 100, 69–79.
2014 journal article
Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices
Electrophoresis, 35(2-3), 352–361.
2013 journal article
Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells
Biomicrofluidics, 7(1), 011809.
2013 journal article
Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices
ELECTROPHORESIS, 35(2-3), 352–361.
2013 journal article
Simultaneous electrokinetic flow and dielectrophoretic trapping using perpendicular static and dynamic electric fields
Microfluidics and Nanofluidics, 15(5), 599–609.
2012 journal article
Dielectrophoretic differentiation of mouse ovarian surface epithelial cells, macrophages, and fibroblasts using contactless dielectrophoresis
Biomicrofluidics, 6(2), 024104.
2012 conference paper
Investigating Dielectrophoretic Signature of Mouse Ovarian Surface Epithelial Cells, Macrophages and Fibroblasts
ASME 2012 Summer Bioengineering Conference, 35–36.
Event: American Society of Mechanical Engineers
2012 conference paper
Irreversible Electroporation Using the Vasculature of an Organ as Fluid Electrodes
ASME 2012 Summer Bioengineering Conference, 475–476.
Event: American Society of Mechanical Engineers
2012 conference paper
Isolation of rare cancer cells from blood cells using dielectrophoresis
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE, 590–593.
Event: IEEE
2012 chapter
Microfluidic techniques for the detection, manipulation and isolation of rare cells
In Mems for Biomedical Applications (p. 337). Elsevier.
2012 journal article
Multilayer contactless dielectrophoresis: Theoretical considerations
ELECTROPHORESIS, 33(13), 1938–1946.
2011 conference paper
An experimental investigation of temperature changes during electroporation
General Assembly and Scientific Symposium, 2011 XXXth URSI, 1–4.
Event: IEEE
2011 journal article
Contactless dielectrophoretic spectroscopy: Examination of the dielectric properties of cells found in blood
ELECTROPHORESIS, 32(22), 3164–3171.
2011 conference paper
High Frequency Electroporation for Cancer Therapy
ASME 2011 Summer Bioengineering Conference, 481–482.
Event: American Society of Mechanical Engineers
2011 journal article
High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction
BioMedical Engineering OnLine, 10(1), 102.
2011 journal article
Modeling and development of a low frequency contactless dielectrophoresis (cDEP) platform to sort cancer cells from dilute whole blood samples
Biosensors and Bioelectronics, 30(1), 13–20.
2011 journal article
Selective concentration of human cancer cells using contactless dielectrophoresis
ELECTROPHORESIS, 32(18), 2523–2529.
2010 conference paper
Continuous Separation of Particles Using Contactless Dielectrophoresis
ASME 2010 Summer Bioengineering Conference, 611–612.
Event: American Society of Mechanical Engineers
2010 journal article
Electromagnetically Controlled Biological Assembly of Aligned Bacterial Cellulose Nanofibers
Annals of Biomedical Engineering, 38(8), 2475–2484.
2010 journal article
Selective isolation of live/dead cells using contactless dielectrophoresis (cDEP)
Lab on a Chip, 10(4), 438.
2010 journal article
Theoretical Considerations of Tissue Electroporation With High-Frequency Bipolar Pulses
IEEE Transactions on Biomedical Engineering, 58(5), 1474–1482.
2010 journal article
Towards the creation of decellularized organ constructs using irreversible electroporation and active mechanical perfusion
BioMedical Engineering OnLine, 9(1), 83.
2009 journal article
Contactless dielectrophoresis: a new technique for cell manipulation
Biomedical Microdevices, 11(5), 997–1006.
2009 conference paper
Direct control of biological assembly using electrokinetic forces
AIChE Annual Meeting, Nashville, TN, Nov 8-13, 2009.
Employment
Updated: December 29th, 2023 09:33
2023 - present
2017 - 2023
2014 - 2017
Education
Updated: December 29th, 2023 09:36
2014 - 2017
2007 - 2012
2007 - 2010
2002 - 2007
2002 - 2007