Works (5)

2017 journal article

Targeting of Streptococcus mutans Biofilms by a Novel Small Molecule Prevents Dental Caries and Preserves the Oral Microbiome

JOURNAL OF DENTAL RESEARCH, 96(7), 807–814.

By: S. Garcia*, M. Blackledge, S. Michalek*, L. Su*, T. Ptacek*, P. Eipers*, C. Morrow*, E. Lefkowitz*, C. Melander, H. Wu*

author keywords: microbiota; rats; dental enamel; microscopy; bacteria; microbial ecology
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Membrane-Permeabilizing Activity of Reverse-Amide 2-Aminoimidazole Antibiofilm Agents Against Acinetobacter baumannii

CURRENT DRUG DELIVERY, 12(2), 223–230.

By: S. Stowe, R. Thompson, L. Peng, Z. Su, M. Blackledge, G. Draughn, W. Coe, E. Johannes ...

author keywords: 2-aminoimidazole; Acinetobacter baumannii; biofilm; membrane permeabilization; reverse amide; SEM
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Biologically inspired strategies for combating bacterial biofilms

CURRENT OPINION IN PHARMACOLOGY, 13(5), 699–706.

By: M. Blackledge, R. Worthington n & C. Melander

Source: Web Of Science
Added: August 6, 2018

2013 journal article

Programmable DNA-binding small molecules

BIOORGANIC & MEDICINAL CHEMISTRY, 21(20), 6101–6114.

By: M. Blackledge & C. Melander

author keywords: Polyamide; Transcription; Minor groove; DNA binding
Source: Web Of Science
Added: August 6, 2018

2013 review

Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence

[Review of ]. FUTURE MEDICINAL CHEMISTRY, 5(11), 1265–1284.

By: R. Worthington n, M. Blackledge & C. Melander

Source: Web Of Science
Added: August 6, 2018