@misc{zimmer_barycki_simpson_2022, title={Mechanisms of coordinating hyaluronan and glycosaminoglycan production by nucleotide sugars}, volume={322}, ISSN={["1522-1563"]}, DOI={10.1152/ajpcell.00130.2022}, number={6}, journal={AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY}, author={Zimmer, Brenna M. and Barycki, Joseph J. and Simpson, Melanie A.}, year={2022}, month={Jun}, pages={C1201–C1213} }
 @misc{zimmer_barycki_simpson_2021, title={Integration of Sugar Metabolism and Proteoglycan Synthesis by UDP-glucose Dehydrogenase}, volume={69}, ISSN={["1551-5044"]}, DOI={10.1369/0022155420947500}, number={1}, journal={JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY}, author={Zimmer, Brenna M. and Barycki, Joseph J. and Simpson, Melanie A.}, year={2021}, month={Jan}, pages={13–23} }
 @article{hengel_bosso-lefevre_grady_szenker-ravi_li_pierce_lebigot_tan_eio_narayanan_et al._2020, title={Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy}, volume={11}, ISSN={["2041-1723"]}, DOI={10.1038/s41467-020-14360-7}, number={1}, journal={NATURE COMMUNICATIONS}, author={Hengel, Holger and Bosso-Lefevre, Celia and Grady, George and Szenker-Ravi, Emmanuelle and Li, Hankun and Pierce, Sarah and Lebigot, Elise and Tan, Thong-Teck and Eio, Michelle Y. and Narayanan, Gunaseelan and et al.}, year={2020}, month={Jan} }
 @article{nowialis_lopusna_opayska_haney_abraham_sheng_riva_natarajan_guryanova_simpson_et al._2019, title={Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions}, volume={10}, ISSN={["2041-1723"]}, DOI={10.1038/s41467-019-12355-7}, journal={NATURE COMMUNICATIONS}, author={Nowialis, Pawel and Lopusna, Katarina and Opayska, Jana and Haney, Staci L. and Abraham, Ajay and Sheng, Peike and Riva, Alberto and Natarajan, Amarnath and Guryanova, Olga and Simpson, Melanie and et al.}, year={2019}, month={Sep} }
 @article{mcatee_booth_elowsky_zhao_payne_fangman_caplan_henry_simpson_2019, title={Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling}, volume={78-79}, ISSN={["1569-1802"]}, DOI={10.1016/j.matbio.2018.05.002}, journal={MATRIX BIOLOGY}, author={McAtee, Caitlin O. and Booth, Christine and Elowsky, Christian and Zhao, Lei and Payne, Jeremy and Fangman, Teresa and Caplan, Steve and Henry, Michael D. and Simpson, Melanie A.}, year={2019}, month={May}, pages={165–179} }
 @article{grady_thelen_albers_ju_guo_barycki_simpson_2016, title={Inhibiting Hexamer Disassembly of Human UDP-Glucose Dehydrogenase by Photoactivated Amino Acid Cross-Linking}, volume={55}, ISSN={0006-2960 1520-4995}, url={http://dx.doi.org/10.1021/ACS.BIOCHEM.6B00259}, DOI={10.1021/ACS.BIOCHEM.6B00259}, number={22}, journal={Biochemistry}, publisher={American Chemical Society (ACS)}, author={Grady, George and Thelen, Ashley and Albers, Jaleen and Ju, Tong and Guo, Jiantao and Barycki, Joseph J. and Simpson, Melanie A.}, year={2016}, month={May}, pages={3157–3164} }
 @article{zimmer_howell_wei_ma_romsdahl_loughman_markham_seravalli_barycki_simpson_2016, title={Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential}, volume={7}, ISSN={1868-8497 1868-8500}, url={http://dx.doi.org/10.1007/S12672-016-0268-Z}, DOI={10.1007/S12672-016-0268-Z}, number={4}, journal={Hormones and Cancer}, publisher={Springer Nature}, author={Zimmer, Brenna M . and Howell, Michelle E. and Wei, Qin and Ma, Linlin and Romsdahl, Trevor and Loughman, Eileen G. and Markham, Jonathan E. and Seravalli, Javier and Barycki, Joseph J. and Simpson, Melanie A.}, year={2016}, month={Jun}, pages={260–271} }
 @article{mcatee_berkebile_elowsky_fangman_barycki_wahl_khalimonchuk_naslavsky_caplan_simpson_2015, title={Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking}, volume={290}, ISSN={0021-9258 1083-351X}, url={http://dx.doi.org/10.1074/JBC.M115.647446}, DOI={10.1074/JBC.M115.647446}, number={21}, journal={Journal of Biological Chemistry}, publisher={American Society for Biochemistry & Molecular Biology (ASBMB)}, author={McAtee, Caitlin O. and Berkebile, Abigail R. and Elowsky, Christian G. and Fangman, Teresa and Barycki, Joseph J. and Wahl, James K., III and Khalimonchuk, Oleh and Naslavsky, Naava and Caplan, Steve and Simpson, Melanie A.}, year={2015}, month={Apr}, pages={13144–13156} }
 @article{haney_hlady_opavska_klinkebiel_pirruccello_dutta_datta_simpson_wu_opavsky_2015, title={Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis}, volume={34}, ISSN={0950-9232 1476-5594}, url={http://dx.doi.org/10.1038/ONC.2014.472}, DOI={10.1038/ONC.2014.472}, number={43}, journal={Oncogene}, publisher={Springer Nature}, author={Haney, S L and Hlady, R A and Opavska, J and Klinkebiel, D and Pirruccello, S J and Dutta, S and Datta, K and Simpson, M A and Wu, L and Opavsky, R}, year={2015}, month={Feb}, pages={5436–5446} }
 @article{peters_hlady_opavska_klinkebiel_pirruccello_talmon_sharp_wu_jaenisch_simpson_et al._2014, title={Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis}, volume={28}, ISSN={0887-6924 1476-5551}, url={http://dx.doi.org/10.1038/LEU.2013.364}, DOI={10.1038/LEU.2013.364}, number={5}, journal={Leukemia}, publisher={Springer Science and Business Media LLC}, author={Peters, S L and Hlady, R A and Opavska, J and Klinkebiel, D and Pirruccello, S J and Talmon, G A and Sharp, J G and Wu, L and Jaenisch, R and Simpson, M A and et al.}, year={2014}, month={May}, pages={1138–1142} }
 @article{kovar_curtis_othman_simpson_michael olive_2013, title={Characterization of IRDye 800CW chlorotoxin as a targeting agent for brain tumors}, volume={440}, ISSN={0003-2697}, url={http://dx.doi.org/10.1016/J.AB.2013.05.013}, DOI={10.1016/J.AB.2013.05.013}, number={2}, journal={Analytical Biochemistry}, publisher={Elsevier BV}, author={Kovar, Joy L. and Curtis, Evan and Othman, Shadi F. and Simpson, Melanie A. and Michael Olive, D.}, year={2013}, month={Sep}, pages={212–219} }
 @article{hyde_thelen_barycki_simpson_2013, title={UDP-glucose Dehydrogenase Activity and Optimal Downstream Cellular Function Require Dynamic Reorganization at the Dimer-Dimer Subunit Interfaces}, volume={288}, ISSN={0021-9258 1083-351X}, url={http://dx.doi.org/10.1074/JBC.M113.519090}, DOI={10.1074/JBC.M113.519090}, number={49}, journal={Journal of Biological Chemistry}, publisher={American Society for Biochemistry & Molecular Biology (ASBMB)}, author={Hyde, Annastasia S. and Thelen, Ashley M. and Barycki, Joseph J. and Simpson, Melanie A.}, year={2013}, month={Oct}, pages={35049–35057} }
 @article{stephens_saltarrelli jr_balaoing_baggett_nandi_anderson_morrisett_reardon_simpson_weigel_et al._2012, title={Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves}, volume={208}, ISSN={0344-0338}, url={http://dx.doi.org/10.1016/j.prp.2012.08.001}, DOI={10.1016/j.prp.2012.08.001}, number={11}, journal={Pathology - Research and Practice}, publisher={Elsevier BV}, author={Stephens, Elizabeth H. and Saltarrelli Jr, Jerome G. and Balaoing, Liezl R. and Baggett, L. Scott and Nandi, Indrajit and Anderson, Kristin M. and Morrisett, Joel D. and Reardon, Michael J. and Simpson, Melanie A. and Weigel, Paul H. and et al.}, year={2012}, month={Nov}, pages={642–650} }
 @article{simpson_weigel_weigel_2012, title={Systemic blockade of the hyaluronan receptor for endocytosis prevents lymph node metastasis of prostate cancer}, volume={131}, ISSN={0020-7136}, url={http://dx.doi.org/10.1002/ijc.27427}, DOI={10.1002/ijc.27427}, number={5}, journal={International Journal of Cancer}, publisher={Wiley}, author={Simpson, Melanie A. and Weigel, Janet A. and Weigel, Paul H.}, year={2012}, month={Feb}, pages={E836–E840} }
 @article{hyde_farmer_easley_van lammeren_christoffels_barycki_bakkers_simpson_2012, title={UDP-glucose Dehydrogenase Polymorphisms from Patients with Congenital Heart Valve Defects Disrupt Enzyme Stability and Quaternary Assembly}, volume={287}, ISSN={0021-9258 1083-351X}, url={http://dx.doi.org/10.1074/jbc.M112.395202}, DOI={10.1074/jbc.M112.395202}, number={39}, journal={Journal of Biological Chemistry}, publisher={American Society for Biochemistry & Molecular Biology (ASBMB)}, author={Hyde, Annastasia S. and Farmer, Erin L. and Easley, Katherine E. and van Lammeren, Kristy and Christoffels, Vincent M. and Barycki, Joseph J. and Bakkers, Jeroen and Simpson, Melanie A.}, year={2012}, month={Jul}, pages={32708–32716} }
 @article{willis_liu_biterova_simpson_kim_lee_barycki_2011, title={Enzymatic Defects Underlying Hereditary Glutamate Cysteine Ligase Deficiency Are Mitigated by Association of the Catalytic and Regulatory Subunits}, volume={50}, ISSN={0006-2960 1520-4995}, url={http://dx.doi.org/10.1021/bi200708w}, DOI={10.1021/bi200708w}, number={29}, journal={Biochemistry}, publisher={American Chemical Society (ACS)}, author={Willis, Melanie Neely and Liu, Yilin and Biterova, Ekaterina I. and Simpson, Melanie A. and Kim, Heejeong and Lee, Jaekwon and Barycki, Joseph J.}, year={2011}, month={Jul}, pages={6508–6517} }
 @article{bharadwaj_goodrich_mcatee_haferbier_oakley_wahl_simpson_2011, title={Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling}, volume={317}, ISSN={0014-4827}, url={http://dx.doi.org/10.1016/j.yexcr.2011.01.026}, DOI={10.1016/j.yexcr.2011.01.026}, number={8}, journal={Experimental Cell Research}, publisher={Elsevier BV}, author={Bharadwaj, Alamelu G. and Goodrich, Nathaniel P. and McAtee, Caitlin O. and Haferbier, Katie and Oakley, Gregory G. and Wahl, James K., III and Simpson, Melanie A.}, year={2011}, month={May}, pages={1214–1225} }
 @article{kovar_xu_draney_cupp_simpson_olive_2011, title={Near-infrared-labeled tetracycline derivative is an effective marker of bone deposition in mice}, volume={416}, ISSN={0003-2697}, url={http://dx.doi.org/10.1016/j.ab.2011.05.011}, DOI={10.1016/j.ab.2011.05.011}, number={2}, journal={Analytical Biochemistry}, publisher={Elsevier BV}, author={Kovar, Joy L. and Xu, Xinshe and Draney, Dan and Cupp, Andrea and Simpson, Melanie A. and Olive, D. Michael}, year={2011}, month={Sep}, pages={167–173} }
 @article{huang_casale_tian_lele_pisarev_simpson_hemstreet_2010, title={Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer}, volume={126}, ISSN={0020-7136 1097-0215}, url={http://dx.doi.org/10.1002/ijc.24820}, DOI={10.1002/ijc.24820}, number={2}, journal={International Journal of Cancer}, publisher={Wiley}, author={Huang, Dali and Casale, George P. and Tian, Jun and Lele, Subodh M. and Pisarev, Vladimir M. and Simpson, Melanie A. and Hemstreet, George P., III}, year={2010}, month={Jan}, pages={315–327} }
 @article{kovar_volcheck_sevick-muraca_simpson_olive_2009, title={Characterization and performance of a near-infrared 2-deoxyglucose optical imaging agent for mouse cancer models}, volume={384}, ISSN={0003-2697}, url={http://dx.doi.org/10.1016/j.ab.2008.09.050}, DOI={10.1016/j.ab.2008.09.050}, number={2}, journal={Analytical Biochemistry}, publisher={Elsevier BV}, author={Kovar, Joy L. and Volcheck, William and Sevick-Muraca, Eva and Simpson, Melanie A. and Olive, D. Michael}, year={2009}, month={Jan}, pages={254–262} }
 @article{zhang_bharadwaj_casper_barkley_barycki_simpson_2009, title={Hyaluronidase Activity of Human Hyal1 Requires Active Site Acidic and Tyrosine Residues}, volume={284}, ISSN={0021-9258 1083-351X}, url={http://dx.doi.org/10.1074/jbc.M900210200}, DOI={10.1074/jbc.M900210200}, number={14}, journal={Journal of Biological Chemistry}, publisher={American Society for Biochemistry & Molecular Biology (ASBMB)}, author={Zhang, Ling and Bharadwaj, Alamelu G. and Casper, Andrew and Barkley, Joel and Barycki, Joseph J. and Simpson, Melanie A.}, year={2009}, month={Feb}, pages={9433–9442} }
 @article{kovar_simpson_schutz-geschwender_olive_2007, title={A systematic approach to the development of fluorescent contrast agents for optical imaging of mouse cancer models}, volume={367}, ISSN={0003-2697}, url={http://dx.doi.org/10.1016/j.ab.2007.04.011}, DOI={10.1016/j.ab.2007.04.011}, number={1}, journal={Analytical Biochemistry}, publisher={Elsevier BV}, author={Kovar, Joy L. and Simpson, Melanie A. and Schutz-Geschwender, Amy and Olive, D. Michael}, year={2007}, month={Aug}, pages={1–12} }
 @article{easley_sommer_boanca_barycki_simpson_2007, title={Characterization of Human UDP-Glucose Dehydrogenase Reveals Critical Catalytic Roles for Lysine 220 and Aspartate 280}, volume={46}, ISSN={0006-2960 1520-4995}, url={http://dx.doi.org/10.1021/bi061537d}, DOI={10.1021/bi061537d}, number={2}, journal={Biochemistry}, publisher={American Chemical Society (ACS)}, author={Easley, Katherine E. and Sommer, Brandi J. and Boanca, Gina and Barycki, Joseph J. and Simpson, Melanie A.}, year={2007}, month={Jan}, pages={369–378} }
 @article{bharadwaj_rector_simpson_2007, title={Inducible Hyaluronan Production Reveals Differential Effects on Prostate Tumor Cell Growth and Tumor Angiogenesis}, volume={282}, ISSN={0021-9258 1083-351X}, url={http://dx.doi.org/10.1074/jbc.M702964200}, DOI={10.1074/jbc.M702964200}, number={28}, journal={Journal of Biological Chemistry}, publisher={American Society for Biochemistry & Molecular Biology (ASBMB)}, author={Bharadwaj, Alamelu G. and Rector, Katherine and Simpson, Melanie A.}, year={2007}, month={May}, pages={20561–20572} }
 @article{kovar_volcheck_chen_simpson_2007, title={Purification method directly influences effectiveness of an epidermal growth factor-coupled targeting agent for noninvasive tumor detection in mice}, volume={361}, ISSN={0003-2697}, url={http://dx.doi.org/10.1016/j.ab.2006.11.021}, DOI={10.1016/j.ab.2006.11.021}, number={1}, journal={Analytical Biochemistry}, publisher={Elsevier BV}, author={Kovar, Joy L. and Volcheck, William M. and Chen, Jiyan and Simpson, Melanie A.}, year={2007}, month={Feb}, pages={47–54} }
 @article{bharadwaj_kovar_simpson_2006, title={Hyaluronan synthesis and turnover induces metastatic growth}, volume={25}, ISSN={0945-053X}, url={http://dx.doi.org/10.1016/j.matbio.2006.08.110}, DOI={10.1016/j.matbio.2006.08.110}, journal={Matrix Biology}, publisher={Elsevier BV}, author={Bharadwaj, A and Kovar, J and Simpson, M}, year={2006}, month={Nov}, pages={S40–S40} }
 @article{sommer_barycki_simpson_2004, title={Characterization of Human UDP-glucose Dehydrogenase: CYS-276 is required for the second of two successive oxidations}, volume={279}, ISSN={0021-9258 1083-351X}, url={http://dx.doi.org/10.1074/jbc.M401928200}, DOI={10.1074/jbc.M401928200}, number={22}, journal={Journal of Biological Chemistry}, publisher={American Society for Biochemistry & Molecular Biology (ASBMB)}, author={Sommer, Brandi J. and Barycki, Joseph J. and Simpson, Melanie A.}, year={2004}, month={Mar}, pages={23590–23596} }
 @article{yang_price_neudauer_wilson_ferrone_xia_iida_simpson_mccarthy_2004, title={Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms}, volume={165}, ISSN={1540-8140 0021-9525}, url={http://dx.doi.org/10.1083/jcb.200403174}, DOI={10.1083/jcb.200403174}, abstractNote={Melanoma chondroitin sulfate proteoglycan (MCSP) is an early cell surface melanoma progression marker implicated in stimulating tumor cell proliferation, migration, and invasion. Focal adhesion kinase (FAK) plays a pivotal role in integrating growth factor and adhesion-related signaling pathways, facilitating cell spreading and migration. Extracellular signal–regulated kinase (ERK) 1 and 2, implicated in tumor growth and survival, has also been linked to clinical melanoma progression. We have cloned the MCSP core protein and expressed it in the MCSP-negative melanoma cell line WM1552C. Expression of MCSP enhances integrin-mediated cell spreading, FAK phosphorylation, and activation of ERK1/2. MCSP transfectants exhibit extensive MCSP-rich microspikes on adherent cells, where it also colocalizes with α4 integrin. Enhanced activation of FAK and ERK1/2 by MCSP appears to involve independent mechanisms because inhibition of FAK activation had no effect on ERK1/2 phosphorylation. These results indicate that MCSP may facilitate primary melanoma progression by enhancing the activation of key signaling pathways important for tumor invasion and growth.}, number={6}, journal={The Journal of Cell Biology}, publisher={Rockefeller University Press}, author={Yang, Jianbo and Price, Matthew A. and Neudauer, Cheryl L. and Wilson, Christopher and Ferrone, Soldano and Xia, Hong and Iida, Joji and Simpson, Melanie A. and McCarthy, James B.}, year={2004}, month={Jun}, pages={881–891} }