Melissa So Yun Touvron

Works (5)

Updated: November 23rd, 2024 05:02

2024 journal article

Protocol Protocol to culture enteric glial cells from the submucosal and myenteric plexi of neonatal and juvenile pig colons

STAR PROTOCOLS, 5(2).

By: M. Caldwell, C. Cook, C. Mariant, M. Touvron, J. Odle , A. Blikslager , A. Ziegler , L. Van Landeghem

Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024

2023 journal article

Enteric glial cell network function is required for epithelial barrier restitution following intestinal ischemic injury in the early postnatal period

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 326(3), G228–G246.

By: A. Ziegler n , M. Caldwell n, S. Craig, E. Hellstrom n, A. Sheridan n, M. Touvron n, T. Pridgen n, S. Magness* ...

author keywords: enteric glia; epithelial restitution; intestinal barrier; intestinal ischemia; restitution
TL;DR: A neonatal phenotype characterized by a complete lack of coordinated reparative signaling in the mucosal microenvironment is confirmed and important evidence is reported that the subepithelial EGC network changes significantly over the early postnatal period and that proximity of a specific functional population of EGC to wounded intestinal epithelium contributes to intestinal barrier restitution following ischemic injury. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 12, 2024

2021 journal article

PCSK9 is not secreted from mature differentiated intestinal cells

JOURNAL OF LIPID RESEARCH, 62.

By: M. Francois, A. Thedrez *, D. Garcon *, A. Ayer*, T. Sotin *, W. Dijk *, C. Blanchard *, G. Chadeuf * ...

author keywords: intestine; cholesterol metabolism; lipoprotein metabolism; Caco-2 cell; liver-specific knockout; portal blood; systemic blood; Ussing chambers; PCSK9
MeSH headings : Animals; Caco-2 Cells; Cell Differentiation; Cells, Cultured; Humans; Intestine, Small / cytology; Intestine, Small / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Proprotein Convertase 9 / blood; Proprotein Convertase 9 / deficiency; Proprotein Convertase 9 / metabolism
TL;DR: The data demonstrate that mature enterocytes do not secrete PCSK9 and reinforce the central role of the liver in the regulation the concentration of circulating PCSK 9 and consequently of cellular LDL receptors and direct comparison of systemic versus portal blood PC SK9 concentrations confirmed the inability of the small intestine to secretePCSK9 into the portal compartment. (via Semantic Scholar)
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Source: Web Of Science
Added: October 4, 2021

2020 article

iDISCO Allows Complete Visualization and Analysis of Postnatal Enteric Nervous System Development in a Comparative Pig Model

Erwin, S., Touvron, M., Odle, J., Van Landeghem, L., Blikslager, A., & Ziegler, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: S. Erwin  n, M. Touvron*, J. Odle n , L. Van Landeghem n, A. Blikslager n  & A. Ziegler n 

Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 12, 2020

2018 journal article

Enteric glia: Diversity or plasticity?

BRAIN RESEARCH, 1693, 140–145.

By: S. Vales*, M. Touvron* & L. Van Landeghem*

author keywords: Enteric glial cells; Enteric nervous system
MeSH headings : Animals; Enteric Nervous System / cytology; Humans; Nerve Net / cytology; Neuroglia / classification; Neuroglia / physiology
TL;DR: The development of tools and techniques to better appraise enteric glial cells heterogeneity and plasticity will undoubtedly unveil critical regulatory mechanisms implicated in gut health and disease, as well as disorders of the gut-brain axis. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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