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Works (4)
Updated: April 26th, 2024 09:43
2024 journal article
Evaluation of commercial doses of a feed additive and silymarin on broiler performance with and without CCl4-induced liver damage
POULTRY SCIENCE, 103(5).
author keywords: phytogenic feed additive; toxin; poultry; productive performance
Source: Web Of Science
Added: April 22, 2024
2024 article
Expanded library of novel 2,3-pyrrolidinedione analogues exhibit anti-biofilm activity
Nie, M., Valdes-Pena, M. A., Frohock, B. H., Smits, E., Daiker, J. C., Gilbertie, J. M., … Pierce, J. G. (2024, February 1). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol. 99.
author keywords: Natural products; Antibiotics; Antimicrobial resistance; Biofilms; 2 3-pyrrolidinedione
TL;DR:
A new library of 2,3-pyrrolidinedione analogues is reported that expands on the previous report on the antimicrobial studies of this heterocyclic scaffold and displayed antibiofilm properties and represent intriguing scaffolds for further optimization and development.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 7, 2024
2024 article
Total Synthesis and Microbiological Evaluation of Leopolic Acid A and Analogues
Breunig, J. L., Valdes-Pena, M. A., Ratchford, A. W., & Pierce, J. G. (2024, January 12). ACS BIO & MED CHEM AU, Vol. 1.
author keywords: antibiotics; antibiofilm; naturalproducts; multicomponent reactions; heterocycles
pubs.acs.org (publisher PDF)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 13, 2024
2021 review
Leveraging Marine Natural Products as a Platform to Tackle Bacterial Resistance and Persistence
[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 54(8), 1866–1877.
MeSH headings : Alkaloids / chemical synthesis; Alkaloids / pharmacology; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biological Products / chemical synthesis; Biological Products / chemistry; Biological Products / pharmacology; Drug Resistance, Multiple, Bacterial / drug effects; Guanidine / analogs & derivatives; Guanidine / chemical synthesis; Guanidine / pharmacology; Guanidines / chemical synthesis; Guanidines / pharmacology; Microbial Sensitivity Tests; Oxazolidinones / chemical synthesis; Oxazolidinones / pharmacology; Staphylococcus aureus / drug effects; Staphylococcus aureus / physiology; Stereoisomerism; Structure-Activity Relationship
TL;DR:
These studies provide several distinct platforms for the development of novel therapeutics that can add to the arsenal of scaffolds for preclinical development and can provide insight into the biochemical processes and pathways that can be targeted by small molecules in the fight against antimicrobial-resistant and -tolerant infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 19, 2021
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