Matthew William Coco

Works (2)

Updated: July 5th, 2023 15:43

2015 journal article

Interactions with the Bifunctional Interface of the Transcriptional Coactivator DCoH1 Are Kinetically Regulated

JOURNAL OF BIOLOGICAL CHEMISTRY, 290(7), 4319–4329.

By: D. Wang  n, M. Coco n & R. Rose n 

MeSH headings : Animals; Chromatography, Gel; Crystallography, X-Ray; Hydro-Lyases / chemistry; Hydro-Lyases / genetics; Hydro-Lyases / metabolism; Kinetics; Mice; Models, Molecular; Mutation / genetics; Protein Conformation; Protein Folding; Protein Multimerization; Serine / chemistry; Serine / genetics; Serine / metabolism; Threonine / chemistry; Threonine / genetics; Threonine / metabolism; Water / chemistry
TL;DR: It is shown that the DCoH1 homotetramer is kinetically trapped, meaning once it forms it will not dissociate to interact with HNF-1, and that the DCoH1·H NF-1 complex must co-fold to interact. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Environmental drivers of demographics, habitat use, and behavior during a post-Pleistocene radiation of Bahamas mosquitofish (Gambusia hubbsi)

Evolutionary Ecology, 27(5), 971–991.

By: J. Heinen n, M. Coco n, M. Marcuard n, D. White n, M. Peterson  n, R. Martin n, R. Langerhans  n

author keywords: Adaptive radiation; Blue holes; Competition; Ecological divergence; Habitat shift; Predation
TL;DR: Variation in predation risk appears to represent the primary driver of ecological differentiation in this system, but other previously underappreciated factors (interspecific competition, resource availability) are notable contributors as well. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018

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