Works (26)

Updated: August 16th, 2023 21:17

2020 journal article

Cherenkov emissions for studying tumor changes during radiation therapy: An exploratory study in domesticated dogs with naturally-occurring cancer

PLOS ONE, 15(8).

By: A. Rickardโ€‰*, H. Yoshikawa n, G. Palmer n, H. Liu*, M. Dewhirst n, M. Nolan n, X. Zhang

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Dogs; Image Processing, Computer-Assisted; Neoplasms / diagnostic imaging; Neoplasms / radiotherapy; Particle Accelerators; Pilot Projects; Prospective Studies; Radiotherapy Dosage; Tomography, X-Ray Computed; X-Rays
Source: Web Of Science
Added: September 21, 2020

2011 journal article

Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics

CLINICAL CANCER RESEARCH, 17(8), 2549โ€“2560.

By: J. Chiโ€‰ n, D. Thrall n, C. Jiangโ€‰ n, S. Snyder n, D. Fels n, C. Landon n, L. McCall n, L. Lanโ€‰ n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Cluster Analysis; Combined Modality Therapy; Dogs; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomics / methods; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging / methods; Oligonucleotide Array Sequence Analysis; Radiotherapy / methods; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma / genetics; Sarcoma / therapy
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Dynamic Contrast-enhanced Magnetic Resonance Imaging as a Predictor of Clinical Outcome in Canine Spontaneous Soft Tissue Sarcomas Treated with Thermoradiotherapy

CLINICAL CANCER RESEARCH, 15(15), 4993โ€“5001.

By: B. Viglianti n, M. Lora-Michiels n, J. Poulson n, L. Lanโ€‰ n, D. Yu n, L. Sanders n, O. Craciunescu n, Z. Vujaskovic n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Combined Modality Therapy / veterinary; Dog Diseases / diagnosis; Dogs; Hyperthermia, Induced / veterinary; Image Enhancement; Kaplan-Meier Estimate; Magnetic Resonance Imaging / methods; Magnetic Resonance Imaging / veterinary; Prognosis; Radiotherapy / veterinary; Radiotherapy Dosage / veterinary; Sarcoma / diagnosis; Sarcoma / pathology; Sarcoma / veterinary; Soft Tissue Neoplasms / diagnosis; Soft Tissue Neoplasms / pathology; Soft Tissue Neoplasms / veterinary; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018

2007 journal article

A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas

MOLECULAR CANCER THERAPEUTICS, 6(1), 380โ€“389.

By: F. Siddiqui, C. Li*, S. LaRue, J. Poulson*, P. Averyโ€‰*, A. Pruitt n, X. Zhangโ€‰*, R. Ullrich ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Adenoviridae; Animals; Cats; Cytomegalovirus / genetics; Feasibility Studies; Genetic Therapy / adverse effects; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Hyperthermia, Induced; Interleukin-12 / blood; Interleukin-12 / genetics; Interleukin-12 / therapeutic use; Liver / pathology; Mice; Promoter Regions, Genetic / genetics; Recombinant Proteins / adverse effects; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Recombinant Proteins / therapeutic use; Sarcoma / drug therapy; Sarcoma / genetics; Sarcoma / radiotherapy; Sarcoma / veterinary
Source: Web Of Science
Added: August 6, 2018

2006 journal article

A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral Doxil extravasation

CLINICAL CANCER RESEARCH, 12(22), 6800โ€“6807.

By: M. Kleiter*, D. Yu, L. Mohammadian*, N. Niehaus*, I. Spasojevicโ€‰*, L. Sanders*, B. Viglianti*, P. Yarmolenko* ...

co-author countries: Canada ๐Ÿ‡จ๐Ÿ‡ฆ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Antibiotics, Antineoplastic / pharmacokinetics; Antibiotics, Antineoplastic / therapeutic use; Combined Modality Therapy / methods; Diagnostic Imaging / methods; Dose-Response Relationship, Drug; Doxorubicin / pharmacokinetics; Doxorubicin / therapeutic use; Drug Carriers / administration & dosage; Feasibility Studies; Female; Fibrosarcoma / therapy; Hyperthermia, Induced / methods; Liposomes / administration & dosage; Liposomes / pharmacokinetics; Radioactive Tracers; Rats; Technetium Tc 99m Exametazime / administration & dosage; Thigh / radiation effects; Tumor Cells, Cultured; Xenograft Model Antitumor Assays
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 22(5), 365โ€“373.

By: D. Thrall n, S. Larueโ€‰*, A. Pruitt n, B. Case n & M. DeWhirst*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: hyperthermia; radiation therapy; dog; oxygen measurements
MeSH headings : Animals; Cell Hypoxia / physiology; Cell Hypoxia / radiation effects; Combined Modality Therapy / methods; Combined Modality Therapy / veterinary; Dog Diseases / metabolism; Dog Diseases / therapy; Dogs; Hyperthermia, Induced / methods; Hyperthermia, Induced / veterinary; Oxygen / analysis; Oxygen / metabolism; Sarcoma / metabolism; Sarcoma / therapy; Sarcoma / veterinary
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Anesthetic considerations for the study of murine tumor models

Tumor Models in Cancer Research, 407โ€“431.

By: R. Meyer, R. Braun & M. Dewhirst

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Acute pancreatitis associated with administration of a nitric oxide synthase inhibitor in tumor-bearing dogs

In Vivo (Athens, Greece), 14(6), 709โ€“714.

By: J. Poulson, M. Dewhirst, A. Gaskin, Z. Vujaskovic, T. Samulski, D. Prescott, R. Meyer, R. Page, D. Thrall

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas

Clinical Cancer Research, 6(9), 3748โ€“3755.

By: M. Matteucci, G. Anyarambhatla, G. Rosner, C. Azuma, P. Fisher, M. Dewhirst, D. Needham, D. Thrall

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Local 42 degrees C hyperthermia improves vascular conductance of the R3230Ac rat mammary adenocarcinoma during sodium nitroprusside infusion

RADIATION RESEARCH, 154(2), 196โ€“201.

By: R. Meyer n, R. Braun*, G. Rosner* & M. Dewhirst*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 46(1), 179โ€“185.

By: Z. Vujaskovic*, J. Poulson*, A. Gaskin*, D. Thrall n, R. Page n, H. Charlesโ€‰*, . MacFall*, D. Brizelโ€‰* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: tumors; hyperthermia blood how; pO(2); pH; thermal dose
MeSH headings : Animals; Combined Modality Therapy; Dogs; Female; Hydrogen-Ion Concentration; Hyperthermia, Induced / methods; Male; Oxygen / metabolism; Partial Pressure; Sarcoma, Experimental / blood supply; Sarcoma, Experimental / metabolism; Sarcoma, Experimental / radiotherapy; Sarcoma, Experimental / therapy; Soft Tissue Neoplasms / blood supply; Soft Tissue Neoplasms / metabolism; Soft Tissue Neoplasms / radiotherapy; Soft Tissue Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Using units of CEM 43 degrees C T-90, local hyperthermia thermal dose can be delivered as prescribed

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 16(5), 415โ€“428.

By: D. Thrall n, G. Rosnerโ€‰*, C. Azuma n, S. Larueโ€‰*, B. Case n, T. Samulski*, M. Dewhirst*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: dog; hyperthermia; thermal dose
MeSH headings : Animals; Catheterization; Combined Modality Therapy; Dogs; Dose-Response Relationship, Radiation; Hyperthermia, Induced / methods; Radiotherapy / methods; Sarcoma / pathology; Sarcoma / therapy; Sarcoma / veterinary; Temperature; Time Factors
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Tumour cell kinetics as predictors of response in canine lymphoma treated with chemotherapy alone or combined with whole body hyperthermia

International Journal of Hyperthermia, 15(6), 475โ€“486.

By: S. Larueโ€‰*, M. Fox, G. Ogilvie, R. Page*, D. Getzy, D. Thrall*, J. Johnson, M. Dewhirst*, E. Gillette

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Cell Cycle; Combined Modality Therapy; Dog Diseases / drug therapy; Dog Diseases / therapy; Dogs; Doxorubicin / administration & dosage; Hyperthermia, Induced; Indazoles / administration & dosage; Lymphoma / drug therapy; Lymphoma / therapy; Lymphoma / veterinary; Prognosis
Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses

International Journal of Hyperthermia, 15(5), 383โ€“398.

By: D. Thrall, S. Larue, B. Powers, R. Page, J. Johnson, S. George, J. Kornegay, M. McEntee ...

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 13(3), 307โ€“316.

By: M. Hauck*, D. Coffin*, R. Dodge*, M. Dewhirst*, J. Mitchellโ€‰* & M. Zalutsky*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: interstitial fluid pressure; xenograft; hyperthermia
MeSH headings : Animals; Antibodies, Monoclonal / pharmacokinetics; Antibodies, Monoclonal / therapeutic use; Biological Transport, Active; Combined Modality Therapy; Extracellular Space / physiology; Glioma / immunology; Glioma / physiopathology; Glioma / therapy; Humans; Hyperthermia, Induced / methods; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pressure; Time Factors; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model

Clinical Cancer Research, 3, 63โ€“70.

By: M. Hauck, M. Dewhirst, D. Bigner & M. Zaultsky

Source: NC State University Libraries
Added: August 6, 2018

1997 patent

Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders

Washington, DC: U.S. Patent and Trademark Office.

By: M. Dewhirst, R. Meyer, J. Bonaventura & J. DeAngelo

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Stroma-free human hemoglobin a decreases R3230Ac rat mammary adenocarcinoma blood flow and oxygen partial pressure

RADIATION RESEARCH, 147(2), 185โ€“194.

By: J. Hahn*, R. Braunโ€‰*, M. Dewhirst*, S. Shanโ€‰*, S. Snyder*, J. Taubeโ€‰*, E. Ong*, G. Rosnerโ€‰* ...

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: August 6, 2018

1997 chapter

The use of blood substitutes in tumor therapy

In R. R. A. S. Rudolph & G. Z. Feuerstein (Eds.), Red blood cell substitutes: Basic principles and clinical application. New York: Marcel Dekker.

By: R. Meyer & M. Dewhirst

Ed(s): R. A. S. Rudolph & G. Feuerstein

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Phase I evaluation of mitoxantrone alone and combined with whole body hyperthermia in dogs with lymphoma

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 12(3), 309โ€“320.

By: M. Hauck*, G. Price n, G. Ogilvie*, J. Johnson*, E. Gillette*, D. Thrall n, M. Dewhirst*, R. Page*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: hyperthermia; mitoxanthrone; lymphoma; canine
MeSH headings : Animals; Antineoplastic Agents / therapeutic use; Antineoplastic Agents / toxicity; Blood Cell Count / veterinary; Dogs; Female; Fever / veterinary; Lymphoma / metabolism; Lymphoma / therapy; Lymphoma / veterinary; Male; Mitoxantrone / therapeutic use; Mitoxantrone / toxicity; Neutropenia / complications; Neutropenia / veterinary; Neutrophils / metabolism; Regression Analysis; Thrombocytopenia / complications; Thrombocytopenia / veterinary
Source: Web Of Science
Added: August 6, 2018

1996 journal article

The effects of clinically relevant hyperthermic temperatures on the kinetic binding parameters of a monoclonal antibody

NUCLEAR MEDICINE AND BIOLOGY, 23(4), 551โ€“557.

By: M. Hauck*, M. Dewhirst* & M. Zalutsky*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: monoclonal antibodies; hyperthermia; antibody binding kinetics; radiotherapy
MeSH headings : Animals; Antibodies, Monoclonal / metabolism; Antibodies, Monoclonal / pharmacokinetics; Dogs; Glioma / metabolism; Humans; Hyperthermia, Induced; Kinetics; Mice; Mice, Nude; Osteosarcoma / metabolism; Tumor Cells, Cultured
Source: Web Of Science
Added: August 6, 2018

1995 chapter

Enhancement of radiolabeled monoclonal antibody uptake in tumors with local hyperthermia

In Handbook of targeted delivery of imaging agents (pp. 333โ€“359).

By: M. Hauck, M. Dewhirst & M. Zalutsky

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

EFFECT OF WHOLE-BODY HYPERTHERMIA ON CARBOPLATIN DISPOSITION AND TOXICITY IN DOGS

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 10(6), 807โ€“816.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Carboplatin / administration & dosage; Carboplatin / pharmacokinetics; Carboplatin / toxicity; Combined Modality Therapy; Dog Diseases / drug therapy; Dog Diseases / metabolism; Dog Diseases / therapy; Dogs; Dose-Response Relationship, Drug; Female; Hematopoietic System / drug effects; Hyperthermia, Induced / methods; Hyperthermia, Induced / veterinary; Male; Neoplasms / drug therapy; Neoplasms / therapy; Neoplasms / veterinary
Source: Web Of Science
Added: August 6, 2018

1992 journal article

QUANTITATIVE ESTIMATION OF THE THERMAL DOSE-MODIFYING FACTOR FOR CIS-DIAMMINEDICHLOROPLATINUM (CDDP) IN TUMOR-BEARING DOGS

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 8(6), 761โ€“769.

By: R. Page n, D. Thrall n, S. Georgeโ€‰*, G. Price n, G. Heidner n, M. Mcentee n, C. Novotney n, M. Hauck n, M. Dewhirst n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Bone Marrow / drug effects; Combined Modality Therapy; Dog Diseases / drug therapy; Dog Diseases / therapy; Dogs; Drug Tolerance; Female; Hyperthermia, Induced / methods; Hyperthermia, Induced / veterinary; Kidney / drug effects; Male; Neoplasms / drug therapy; Neoplasms / therapy; Neoplasms / veterinary; Organoplatinum Compounds / administration & dosage; Organoplatinum Compounds / adverse effects
Source: Web Of Science
Added: August 6, 2018

1987 journal article

PHARMACOKINETICS AND TOXICITY OF INTRAPERITONEAL CISPLATIN COMBINED WITH REGIONAL HYPERTHERMIA

JOURNAL OF CLINICAL ONCOLOGY, 5(10), 1613โ€“1620.

By: E. Zakris, M. Dewhirst*, J. Riviere*, P. Hoopes, R. Page & . Oleson

MeSH headings : Animals; Cisplatin / blood; Cisplatin / pharmacokinetics; Cisplatin / toxicity; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Hepatitis, Animal / etiology; Hyperthermia, Induced / adverse effects; Injections, Intraperitoneal; Lymph Nodes / pathology; Male; Ovarian Neoplasms; Peritonitis / etiology; Pulmonary Fibrosis / etiology; Temperature; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018

1986 journal article

Effect of hyperthermia on cisplatin pharmacokinetics in normal dogs

International Journal of Hyperthermia, 2, 351โ€“358.

By: J. Riviere n, R. Page n, M. Dewhirst*, K. Tyczkowska n & D. Thrall n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Biotransformation; Cisplatin / blood; Cisplatin / metabolism; Dogs; Half-Life; Hyperthermia, Induced / methods; Kinetics; Platinum / blood; Spectrophotometry, Atomic; Ultrafiltration
Source: NC State University Libraries
Added: August 6, 2018

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