Mark Dewhirst

Rickard, A. G., Yoshikawa, H., Palmer, G. M., Liu, H. Q., Dewhirst, M. W., Nolan, M. W., & Zhang, X. (2020). Cherenkov emissions for studying tumor changes during radiation therapy: An exploratory study in domesticated dogs with naturally-occurring cancer. PLOS ONE, 15(8). https://doi.org/10.1371/journal.pone.0238106

Chi, J.-T., Thrall, D. E., Jiang, C., Snyder, S., Fels, D., Landon, C., … Dewhirst, M. W. (2011). Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics. CLINICAL CANCER RESEARCH, 17(8), 2549–2560. https://doi.org/10.1158/1078-0432.ccr-10-2583

Viglianti, B. L., Lora-Michiels, M., Poulson, J. M., Lan, L., Yu, D., Sanders, L., … Dewhirst, M. W. (2009). Dynamic Contrast-enhanced Magnetic Resonance Imaging as a Predictor of Clinical Outcome in Canine Spontaneous Soft Tissue Sarcomas Treated with Thermoradiotherapy. CLINICAL CANCER RESEARCH, 15(15), 4993–5001. https://doi.org/10.1158/1078-0432.CCR-08-2222

Siddiqui, F., Li, C.-Y., LaRue, S. M., Poulson, J. M., Avery, P. R., Pruitt, A. F., … Hauck, M. L. (2007). A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas. MOLECULAR CANCER THERAPEUTICS, 6(1), 380–389. https://doi.org/10.1158/1535-7163.MCT-06-0342

Kleiter, M. M., Yu, D., Mohammadian, L. A., Niehaus, N., Spasojevic, I., Sanders, L., … Thrall, D. E. (2006). A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral Doxil extravasation. CLINICAL CANCER RESEARCH, 12(22), 6800–6807. https://doi.org/10.1158/1078-0432.CCR-06-0839

Thrall, D. E., Larue, S. M., Pruitt, A. F., Case, B., & DeWhirst, M. W. (2006). Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 22(5), 365–373. https://doi.org/10.1080/02656730600836386

Meyer, R. E., Braun, R. D., & Dewhirst, M. W. (2001). Anesthetic considerations for the study of murine tumor models. Tumor Models in Cancer Research, 407–431.

Poulson, J. M., Dewhirst, M. W., Gaskin, A. A., Vujaskovic, Z., Samulski, T. V., Prescott, D. M., … Thrall, D. E. (2000). Acute pancreatitis associated with administration of a nitric oxide synthase inhibitor in tumor-bearing dogs. In Vivo (Athens, Greece), 14(6), 709–714.

Matteucci, M. L., Anyarambhatla, G., Rosner, G., Azuma, C., Fisher, P. E., Dewhirst, M. W., … Thrall, D. E. (2000). Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas. Clinical Cancer Research, 6(9), 3748–3755.

Meyer, R. E., Braun, R. D., Rosner, G. L., & Dewhirst, M. W. (2000). Local 42 degrees C hyperthermia improves vascular conductance of the R3230Ac rat mammary adenocarcinoma during sodium nitroprusside infusion. RADIATION RESEARCH, 154(2), 196–201. https://doi.org/10.1667/0033-7587(2000)154[0196:LCHIVC]2.0.CO;2

Vujaskovic, Z., Poulson, J. M., Gaskin, A. A., Thrall, D. E., Page, R. L., Charles, H. C., … Dewhirst, M. W. (2000). Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 46(1), 179–185. https://doi.org/10.1016/s0360-3016(99)00362-4

Thrall, D. E., Rosner, G. L., Azuma, C., Larue, S. M., Case, B. C., Samulski, T., & Dewhirst, M. W. (2000). Using units of CEM 43 degrees C T-90, local hyperthermia thermal dose can be delivered as prescribed. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 16(5), 415–428. https://doi.org/10.1080/026567300416712

Larue, S. M., Fox, M. H., Ogilvie, G. K., Page, R. L., Getzy, D. M., Thrall, D. E., … Gillette, E. L. (1999). Tumour cell kinetics as predictors of response in canine lymphoma treated with chemotherapy alone or combined with whole body hyperthermia. International Journal of Hyperthermia, 15(6), 475–486. https://doi.org/10.1080/026567399285477

Thrall, D. E., Larue, S. M., Powers, B. E., Page, R. L., Johnson, J., George, S. L., … Gillette, E. L. (1999). Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses. International Journal of Hyperthermia, 15(5), 383–398.

Hauck, M. L., Coffin, D. O., Dodge, R. K., Dewhirst, M. W., Mitchell, J. B., & Zalutsky, M. R. (1997). A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 13(3), 307–316. https://doi.org/10.3109/02656739709023538

Hauck, M. L., Dewhirst, M. W., Bigner, D. D., & Zaultsky, M. R. (1997). Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model. Clinical Cancer Research, 3, 63–70.

Dewhirst, M. W., Meyer, R. E., Bonaventura, J., & DeAngelo, J. (1997). Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders. Washington, DC: U.S. Patent and Trademark Office.

Hahn, J. S., Braun, R. D., Dewhirst, M. W., Shan, S. Q., Snyder, S. A., Taube, J. M., … Meyer, R. E. (1997). Stroma-free human hemoglobin a decreases R3230Ac rat mammary adenocarcinoma blood flow and oxygen partial pressure. RADIATION RESEARCH, 147(2), 185–194. https://doi.org/10.2307/3579420

Meyer, R. E., & Dewhirst, M. W. (1997). The use of blood substitutes in tumor therapy. In R. R. A. S. Rudolph & G. Z. Feuerstein (Eds.), Red blood cell substitutes: Basic principles and clinical application. New York: Marcel Dekker.

Hauck, M. L., Price, G. S., Ogilvie, G. K., Johnson, J., Gillette, E. L., Thrall, D. E., … Page, R. L. (1996). Phase I evaluation of mitoxantrone alone and combined with whole body hyperthermia in dogs with lymphoma. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 12(3), 309–320. https://doi.org/10.3109/02656739609022520

Hauck, M. L., Dewhirst, M. W., & Zalutsky, M. R. (1996). The effects of clinically relevant hyperthermic temperatures on the kinetic binding parameters of a monoclonal antibody. NUCLEAR MEDICINE AND BIOLOGY, 23(4), 551–557. https://doi.org/10.1016/0969-8051(96)00039-x

Hauck, M. L., Dewhirst, M. W., & Zalutsky, M. R. (1995). Enhancement of radiolabeled monoclonal antibody uptake in tumors with local hyperthermia. In Handbook of targeted delivery of imaging agents (pp. 333–359).

PAGE, R. L., MCENTEE, M. C., WILLIAMS, P. L., GEORGE, S. L., PRICE, G. S., NOVOTNEY, C. A., … THRALL, D. E. (1994). EFFECT OF WHOLE-BODY HYPERTHERMIA ON CARBOPLATIN DISPOSITION AND TOXICITY IN DOGS. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 10(6), 807–816. https://doi.org/10.3109/02656739409012373

PAGE, R. L., THRALL, D. E., GEORGE, S. L., PRICE, G. S., HEIDNER, G. L., MCENTEE, M. C., … DEWHIRST, M. W. (1992). QUANTITATIVE ESTIMATION OF THE THERMAL DOSE-MODIFYING FACTOR FOR CIS-DIAMMINEDICHLOROPLATINUM (CDDP) IN TUMOR-BEARING DOGS. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 8(6), 761–769. https://doi.org/10.3109/02656739209005024

ZAKRIS, E. L., DEWHIRST, M. W., RIVIERE, J. E., HOOPES, P. J., PAGE, R. L., & OLESON, JR. (1987). PHARMACOKINETICS AND TOXICITY OF INTRAPERITONEAL CISPLATIN COMBINED WITH REGIONAL HYPERTHERMIA. JOURNAL OF CLINICAL ONCOLOGY, 5(10), 1613–1620. https://doi.org/10.1200/JCO.1987.5.10.1613

Riviere, J. E., Page, R. L., Dewhirst, M. W., Tyczkowska, K., & Thrall, D. E. (1986). Effect of hyperthermia on cisplatin pharmacokinetics in normal dogs. International Journal of Hyperthermia, 2, 351–358. https://doi.org/10.3109/02656738609004965