@article{bang_bergman_li_mukherjee_alshehri_abbott_crook_velev_hall_you_2023, title={An integrated chemical engineering approach to understanding microplastics}, volume={1}, ISSN={["1547-5905"]}, DOI={10.1002/aic.18020}, journal={AICHE JOURNAL}, author={Bang, Rachel S. and Bergman, Michael and Li, Tianyu and Mukherjee, Fiona and Alshehri, Abdulelah S. and Abbott, Nicholas L. and Crook, Nathan C. and Velev, Orlin D. and Hall, Carol K. and You, Fengqi}, year={2023}, month={Jan} } @article{sarma_catella_pedro_xiao_durmusoglu_menegatti_crook_magness_hall_2023, title={Design of 8-mer Peptides that BlockClostridioides difficileToxin A in Intestinal Cells}, url={https://doi.org/10.1101/2023.01.10.523493}, DOI={10.1101/2023.01.10.523493}, author={Sarma, Sudeep and Catella, Carly M. and Pedro, Ellyce T. San and Xiao, Xingqing and Durmusoglu, Deniz and Menegatti, Stefano and Crook, Nathan and Magness, Scott T. and Hall, Carol K.}, year={2023}, month={Jan} } @misc{heavey_durmusoglu_crook_anselmo_2022, title={Discovery and delivery strategies for engineered live biotherapeutic products}, volume={40}, ISSN={["1879-3096"]}, DOI={10.1016/j.tibtech.2021.08.002}, number={3}, journal={TRENDS IN BIOTECHNOLOGY}, author={Heavey, Mairead K. and Durmusoglu, Deniz and Crook, Nathan and Anselmo, Aaron C.}, year={2022}, month={Mar}, pages={354–369} } @article{jensen_deichmann_ma_vilandt_schiesaro_rojek_lengger_eliasson_vento_durmusoglu_et al._2022, title={Engineered cell differentiation and sexual reproduction in probiotic and mating yeasts}, volume={13}, ISSN={["2041-1723"]}, DOI={10.1038/s41467-022-33961-y}, number={1}, journal={NATURE COMMUNICATIONS}, author={Jensen, Emil D. and Deichmann, Marcus and Ma, Xin and Vilandt, Rikke U. and Schiesaro, Giovanni and Rojek, Marie B. and Lengger, Bettina and Eliasson, Line and Vento, Justin M. and Durmusoglu, Deniz and et al.}, year={2022}, month={Oct} } @article{kwak_crook_yoneda_ahn_ning_cheng_dantas_2022, title={Functional mining of novel terpene synthases from metagenomes}, volume={15}, ISSN={["2731-3654"]}, DOI={10.1186/s13068-022-02189-9}, number={1}, journal={BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS}, author={Kwak, Suryang and Crook, Nathan and Yoneda, Aki and Ahn, Naomi and Ning, Jie and Cheng, Jiye and Dantas, Gautam}, year={2022}, month={Oct} } @article{durmusoglu_al’abri_williams_collins_martínez_crook_2022, title={Improving Therapeutic Protein Secretion in the Probiotic YeastSaccharomyces boulardiiusing a Multifactorial Engineering Approach}, url={https://doi.org/10.1101/2022.12.30.522352}, DOI={10.1101/2022.12.30.522352}, author={Durmusoglu, Deniz and Al’Abri, Ibrahim and Williams, Taufika Islam and Collins, Leonard B. and Martínez, José L. and Crook, Nathan}, year={2022}, month={Dec} } @article{al'abri_haller_li_crook_2022, title={Inducible directed evolution of complex phenotypes in bacteria}, volume={2}, ISSN={["1362-4962"]}, url={https://doi.org/10.1093/nar/gkac094}, DOI={10.1093/nar/gkac094}, journal={NUCLEIC ACIDS RESEARCH}, publisher={Oxford University Press (OUP)}, author={Al'Abri, Ibrahim S. and Haller, Daniel J. and Li, Zidan and Crook, Nathan}, year={2022}, month={Feb} } @article{kwon_cheeseman_frias-de-diego_hong_yang_jung_yin_murdoch_scholle_crook_et al._2021, title={A Liquid Metal Mediated Metallic Coating for Antimicrobial and Antiviral Fabrics}, volume={9}, ISSN={["1521-4095"]}, url={http://europepmc.org/abstract/med/34550628}, DOI={10.1002/adma.202104298}, journal={ADVANCED MATERIALS}, author={Kwon, Ki Yoon and Cheeseman, Samuel and Frias-De-Diego, Alba and Hong, Haeleen and Yang, Jiayi and Jung, Woojin and Yin, Hong and Murdoch, Billy J. and Scholle, Frank and Crook, Nathan and et al.}, year={2021}, month={Sep} } @article{durmusoglu_catella_purnell_menegatti_crook_2021, title={Design and in situ biosynthesis of precision therapies against gastrointestinal pathogens}, volume={23}, ISSN={["2468-8673"]}, DOI={10.1016/j.cophys.2021.06.007}, journal={CURRENT OPINION IN PHYSIOLOGY}, author={Durmusoglu, Deniz and Catella, Carly M. and Purnell, Ethan F. and Menegatti, Stefano and Crook, Nathan C.}, year={2021}, month={Oct} } @article{xiao_sarma_menegatti_crook_magness_hall_2021, title={In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A}, volume={17}, ISSN={["1554-8937"]}, url={https://doi.org/10.1021/acschembio.1c00743}, DOI={10.1021/acschembio.1c00743}, number={1}, journal={ACS CHEMICAL BIOLOGY}, publisher={American Chemical Society (ACS)}, author={Xiao, Xingqing and Sarma, Sudeep and Menegatti, Stefano and Crook, Nathan and Magness, Scott T. and Hall, Carol K.}, year={2021}, month={Dec} } @article{durmusoglu_al'abri_collins_cheng_eroglu_beisel_crook_2021, title={In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii}, volume={10}, ISSN={["2161-5063"]}, url={https://doi.org/10.1021/acssynbio.0c00562}, DOI={10.1021/acssynbio.0c00562}, number={5}, journal={ACS SYNTHETIC BIOLOGY}, publisher={American Chemical Society (ACS)}, author={Durmusoglu, Deniz and Al'Abri, Ibrahim S. and Collins, Scott P. and Cheng, Junrui and Eroglu, Abdulkerim and Beisel, Chase L. and Crook, Nathan}, year={2021}, month={May}, pages={1039–1052} } @article{al'abri_durmusoglu_crook_2021, title={What E. coli knows about your 1-year-old infant: Antibiotic use, lifestyle, birth mode, and siblings}, volume={29}, ISSN={["1934-6069"]}, DOI={10.1016/j.chom.2021.05.006}, number={6}, journal={CELL HOST & MICROBE}, author={Al'Abri, Ibrahim S. and Durmusoglu, Deniz and Crook, Nathan}, year={2021}, month={Jun}, pages={854–855} } @article{durmusoglu_al’abri_collins_beisel_crook_2020, title={Establishing Probiotic Saccharomyces boulardii as a Model Organism for Synthesis and Delivery of Biomolecules}, volume={1}, url={https://doi.org/10.1101/2020.01.22.915389}, DOI={10.1101/2020.01.22.915389}, publisher={Cold Spring Harbor Laboratory}, author={Durmusoglu, Deniz and Al’Abri, Ibrahim and Collins, Scott P. and Beisel, Chase and Crook, Nathan}, year={2020}, month={Jan} } @article{al’abri_haller_crook_2020, title={Inducible Directed Evolution of Complex Phenotypes in Bacteria}, volume={10}, url={https://doi.org/10.1101/2020.10.30.362871}, DOI={10.1101/2020.10.30.362871}, publisher={Cold Spring Harbor Laboratory}, author={Al’Abri, Ibrahim S. and Haller, Daniel J. and Crook, Nathan}, year={2020}, month={Oct} } @article{crook_ferreiro_condiotte_dantas_2020, title={Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in E. coli Nissle Residing in the Mammalian Gut}, volume={9}, ISSN={["2161-5063"]}, url={https://doi.org/10.1021/acssynbio.0c00040}, DOI={10.1021/acssynbio.0c00040}, number={5}, journal={ACS SYNTHETIC BIOLOGY}, publisher={American Chemical Society (ACS)}, author={Crook, Nathan and Ferreiro, Aura and Condiotte, Zevin and Dantas, Gautam}, year={2020}, month={May}, pages={1010–1021} } @article{crook_ferreiro_gasparrini_pesesky_gibson_wang_sun_condiotte_dobrowolski_peterson_et al._2019, title={Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut}, volume={25}, ISSN={["1934-6069"]}, url={https://doi.org/10.1016/j.chom.2019.02.005}, DOI={10.1016/j.chom.2019.02.005}, number={4}, journal={CELL HOST & MICROBE}, publisher={Elsevier BV}, author={Crook, Nathan and Ferreiro, Aura and Gasparrini, Andrew J. and Pesesky, Mitchell W. and Gibson, Molly K. and Wang, Bin and Sun, Xiaoqing and Condiotte, Zevin and Dobrowolski, Stephen and Peterson, Daniel and et al.}, year={2019}, month={Apr}, pages={499-+} } @misc{vento_crook_beisel_2019, title={Barriers to genome editing with CRISPR in bacteria}, volume={46}, ISSN={["1476-5535"]}, url={https://doi.org/10.1007/s10295-019-02195-1}, DOI={10.1007/s10295-019-02195-1}, number={9-10}, journal={JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY}, publisher={Springer Science and Business Media LLC}, author={Vento, Justin M. and Crook, Nathan and Beisel, Chase L.}, year={2019}, month={Oct}, pages={1327–1341} } @article{crook_ferreiro_gasparrini_pesesky_gibson_wang_sun_condiotte_dobrowolski_peterson_et al._2018, title={Adaptive strategies of the candidate probiotic E. coli Nissle in the mammalian gut}, volume={7}, url={https://doi.org/10.1101/364505}, DOI={10.1101/364505}, publisher={Cold Spring Harbor Laboratory}, author={Crook, Nathan and Ferreiro, Aura and Gasparrini, Andrew J. and Pesesky, Mitchell and Gibson, Molly K. and Wang, Bin and Sun, Xiaoqing and Condiotte, Zevin and Dobrowolski, Stephen and Peterson, Daniel and et al.}, year={2018}, month={Jul} } @article{crook_abatemarco_sun_wagner_schmitz_alper_2016, title={In vivo continuous evolution of genes and pathways in yeast}, url={https://doi.org/10.1038/ncomms13051}, DOI={10.1038/ncomms13051}, journal={Nature Communications}, author={Crook, Nathan and Abatemarco, Joseph and Sun, Jie and Wagner, James M. and Schmitz, Alexander and Alper, Hal S.}, year={2016}, month={Oct} } @article{curran_crook_karim_gupta_wagman_alper_2014, title={Design of synthetic yeast promoters via tuning of nucleosome architecture}, volume={5}, DOI={10.1038/ncomms5002}, journal={Nat Comms}, publisher={Nature Publishing Group}, author={Curran, Kathleen A. and Crook, Nathan C. and Karim, Ashty S. and Gupta, Akash and Wagman, Allison M. and Alper, Hal S.}, year={2014}, month={May} } @article{crook_schmitz_alper_2014, title={Optimization of a Yeast RNA Interference System for Controlling Gene Expression and Enabling Rapid Metabolic Engineering}, volume={3}, DOI={10.1021/sb4001432}, number={5}, journal={ACS Synth. Biol.}, publisher={American Chemical Society (\lbraceACS\rbrace)}, author={Crook, Nathan C. and Schmitz, Alexander C. and Alper, Hal S.}, year={2014}, month={May}, pages={307–313} } @article{crook_alper_2013, title={Model-based design of synthetic, biological systems}, volume={103}, DOI={10.1016/j.ces.2012.12.022}, journal={Chemical Engineering Science}, publisher={Elsevier \lbraceBV\rbrace}, author={Crook, Nathan and Alper, Hal S.}, year={2013}, month={Nov}, pages={2–11} } @article{crook_alper_2012, title={Classical Strain Improvement}, DOI={10.1002/9781118433034.ch1}, journal={Engineering Complex Phenotypes in Industrial Strains}, publisher={John Wiley & Sons, Inc.}, author={Crook, Nathan and Alper, Hal S.}, year={2012}, month={Oct}, pages={1–33} } @article{lanza_crook_alper_2012, title={Innovation at the intersection of synthetic and systems biology}, volume={23}, DOI={10.1016/j.copbio.2011.12.026}, number={5}, journal={Current Opinion in Biotechnology}, publisher={Elsevier \lbraceBV\rbrace}, author={Lanza, Amanda M and Crook, Nathan C and Alper, Hal S}, year={2012}, month={Oct}, pages={712–717} } @article{lanza_blazeck_crook_alper_2012, title={Linking Yeast Gcn5p Catalytic Function and Gene Regulation Using a Quantitative, Graded Dominant Mutant Approach}, volume={7}, DOI={10.1371/journal.pone.0036193}, number={4}, journal={PLoS ONE}, publisher={Public Library of Science (\lbracePLoS\rbrace)}, author={Lanza, Amanda M. and Blazeck, John J. and Crook, Nathan C. and Alper, Hal S.}, editor={Chan, ChristinaEditor}, year={2012}, month={Apr}, pages={e36193} } @article{brustad_lelyveld_snow_crook_jung_martinez_scholl_jasanoff_arnold_2012, title={Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin}, volume={422}, DOI={10.1016/j.jmb.2012.05.029}, number={2}, journal={Journal of Molecular Biology}, publisher={Elsevier \lbraceBV\rbrace}, author={Brustad, Eric M. and Lelyveld, Victor S. and Snow, Christopher D. and Crook, Nathan and Jung, Sang Taek and Martinez, Francisco M. and Scholl, Timothy J. and Jasanoff, Alan and Arnold, Frances H.}, year={2012}, month={Sep}, pages={245–262} } @article{crook_freeman_alper_2011, title={Re-engineering multicloning sites for function and convenience}, volume={39}, DOI={10.1093/nar/gkr346}, number={14}, journal={Nucleic Acids Research}, publisher={Oxford University Press (\lbraceOUP\rbrace)}, author={Crook, N. C. and Freeman, E. S. and Alper, H. S.}, year={2011}, month={May}, pages={e92–e92} } @article{curran_crook_alper_2011, title={Using Flux Balance Analysis to Guide Microbial Metabolic Engineering}, DOI={10.1007/978-1-61779-483-4_13}, journal={Microbial Metabolic Engineering}, publisher={Springer Science \mathplus Business Media}, author={Curran, Kathleen A. and Crook, Nathan C. and Alper, Hal S.}, year={2011}, month={Nov}, pages={197–216} } @article{fasan_crook_peters_meinhold_buelter_landwehr_cirino_arnold_2010, title={Improved product-per-glucose yields in P450-dependent propane biotransformations using engineered Escherichia coli}, volume={108}, DOI={10.1002/bit.22984}, number={3}, journal={Biotechnol. Bioeng.}, publisher={Wiley-Blackwell}, author={Fasan, Rudi and Crook, Nathan C. and Peters, Matthew W. and Meinhold, Peter and Buelter, Thomas and Landwehr, Marco and Cirino, Patrick C. and Arnold, Frances H.}, year={2010}, month={Nov}, pages={500–510} } @article{fasan_chen_crook_arnold_2007, title={Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties}, volume={119}, DOI={10.1002/ange.200702616}, number={44}, journal={Angew. Chem.}, publisher={Wiley-Blackwell}, author={Fasan, Rudi and Chen, Mike M. and Crook, Nathan C. and Arnold, Frances H.}, year={2007}, month={Nov}, pages={8566–8570} } @article{fasan_chen_crook_arnold_2007, title={Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties}, volume={46}, DOI={10.1002/anie.200702616}, number={44}, journal={Angew. Chem. Int. Ed.}, publisher={Wiley-Blackwell}, author={Fasan, Rudi and Chen, Mike M. and Crook, Nathan C. and Arnold, Frances H.}, year={2007}, month={Nov}, pages={8414–8418} }