Nicholas David Manzo

Works (4)

Updated: July 8th, 2023 11:15

2013 journal article

Diesel exhaust particles induce aberrant alveolar epithelial directed cell movement by disruption of polarity mechanisms

Journal of Toxicology and Environmental Health. Part A, 76(2), 71–85.

By: A. LaGier, N. Manzo & J. Dye

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Nitric oxide and superoxide mediate diesel particle effects in cytokine-treated mice and murine lung epithelial cells - implications for susceptibility to traffic-related air pollution

Particle and Fibre Toxicology, 9.

By: N. Manzo, A. LaGier, R. Slade, A. Ledbetter, J. Richards & J. Dye

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Susceptibility of Inflamed Alveolar and Airway Epithelial Cells to Injury Induced by Diesel Exhaust Particles of Varying Organic Carbon Content

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 73(8), 565–580.

By: N. Manzo n, R. Slade*, J. Richards*, J. McGee*, L. Martin n & J. Dye *

MeSH headings : Actins / metabolism; Air Pollutants / chemistry; Air Pollutants / toxicity; Animals; Carbon / toxicity; Cells, Cultured; Glutathione / metabolism; Heme Oxygenase-1 / metabolism; L-Lactate Dehydrogenase / metabolism; Mice; Particulate Matter / chemistry; Particulate Matter / toxicity; Pulmonary Alveoli / drug effects; Respiratory Mucosa / cytology; Respiratory Mucosa / drug effects; Vehicle Emissions / toxicity
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Source: Web Of Science
Added: August 6, 2018

2008 journal article

A Hyperlipidemic Rabbit Model Provides New Insights into Pulmonary Zinc Exposure Effects on Cardiovascular Health

CARDIOVASCULAR TOXICOLOGY, 8(4), 195–206.

By: A. LaGier *, N. Manzo n, A. Carll *, R. Jaskot*, R. Slade*, J. Richards*, D. Winsett*, A. Farraj *, J. Dye*

author keywords: Zinc; Rabbit; Cardiovascular; Particulate matter; Hyperlipidemia
MeSH headings : Acetylglucosaminidase / analysis; Animals; Atherosclerosis / chemically induced; Atherosclerosis / metabolism; Bronchoalveolar Lavage Fluid / chemistry; Bronchoalveolar Lavage Fluid / cytology; Cholesterol / blood; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione Disulfide / analysis; Heart Rate / drug effects; Heart Rate / physiology; Hyperlipidemias / chemically induced; Hyperlipidemias / metabolism; Inhalation Exposure; Intubation, Intratracheal; Leukocyte Count; Lung / drug effects; Lung / metabolism; Male; Nitrites / blood; Particulate Matter / toxicity; Rabbits; Zinc Oxide / toxicity; Zinc Sulfate / toxicity
TL;DR: The study elucidates mechanisms by which the zinc metal component of PM drives cardiovascular health effects, as well as the possible susceptibility induced by hyperlipidemia, and exemplifies the benefits of monitoring circulatory physiology during exposure as to after exposure. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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