Nafisa Islam

Works (5)

Updated: July 5th, 2023 15:44

2019 journal article

Use of a Branched Linker for Enhanced Biosensing Properties in IgG Detection from Mixed Chinese Hamster Ovary Cell Cultures

BIOCONJUGATE CHEMISTRY, 30(3), 815–825.

By: N. Islam n, P. Gurgel n, O. Rojas n & R. Carbonell n

MeSH headings : Adsorption; Amino Acid Sequence; Animals; Biosensing Techniques; CHO Cells; Complex Mixtures; Cricetinae; Cricetulus; Immunoglobulin G / analysis; Kinetics; Peptides / chemistry
TL;DR: The branched amines increased the overall sensitivity and selectivity for IgG adsorption from complex mixtures of Chinese hamster ovary supernatant (CHO) and regeneration studies were carried out. (via Semantic Scholar)
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Source: Web Of Science
Added: April 9, 2019

2014 journal article

Dynamic and equilibrium performance of sensors based on short peptide ligands for affinity adsorption of human IgG using surface plasmon resonance

BIOSENSORS & BIOELECTRONICS, 58, 380–387.

By: N. Islam n, F. Shen  n, P. Gurgel n, O. Rojas n & R. Carbonell n

author keywords: Hexamer; Protein A; Human immunoglobulin G; Self-assembled monolayers; Adsorption rate constant; Desorption rate constant
MeSH headings : Adsorption; Antibody Affinity / immunology; Binding Sites; Biosensing Techniques / instrumentation; Equipment Design; Equipment Failure Analysis; Immunoglobulin G / chemistry; Immunoglobulin G / immunology; Peptides / chemistry; Peptides / immunology; Protein Binding; Protein Interaction Mapping / instrumentation; Surface Plasmon Resonance / instrumentation
TL;DR: This paper characterizes the potential of novel hexameric peptide ligands for on-line IgG detection in bioprocesses and finds that the peptide-IgG binding was reaction controlled, however the protein A-IGG binding mechanism was partially mass transfer (diffusion) controlled. (via Semantic Scholar)
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Added: August 6, 2018

2014 journal article

Effects of Composition of Oligo(ethylene glycol)-Based Mixed Monolayers on Peptide Grafting and Human Immunoglobulin Detection

JOURNAL OF PHYSICAL CHEMISTRY C, 118(10), 5361–5373.

By: N. Islam n, P. Gurgel n, O. Rojas n & R. Carbonell n

TL;DR: The specificity toward IgG was optimal for peptides grafted on SAMs prepared from 10% EG6NH2 precursor solution, even though this surface did not have the highest number of peptides per unit area. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Specificity and Regenerability of Short Peptide Ligands Supported on Polymer Layers for Immunoglobulin G Binding and Detection

ACS APPLIED MATERIALS & INTERFACES, 5(16), 8030–8037.

By: Y. Zhang n, N. Islam n, R. Carbonell n & O. Rojas n

author keywords: short peptide ligands; immunoglobulin G detection; surface plasmon resonance; quartz crystal microgravimetry; regenerability; storage stability
MeSH headings : Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Ligands; Methacrylates / chemistry; Peptides / chemistry; Polyhydroxyethyl Methacrylate / chemistry; Polymers / chemistry; Protein Binding; Surface Plasmon Resonance
TL;DR: Results from sodium dodecyl sulfate polyacrylamide gel electrophoresis and fluorescence microscopy indicate that the bioactive system is highly specific to IgG and resistant to nonspecific interactions when tested in mixed protein solutions. (via Semantic Scholar)
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Added: August 6, 2018

2012 journal article

Specific Binding of Immunoglobulin G with Bioactive Short Peptides Supported on Antifouling Copolymer Layers for Detection in Quartz Crystal Microgravimetry and Surface Plasmon Resonance

ANALYTICAL CHEMISTRY, 85(2), 1106–1113.

By: Y. Zhang n, N. Islam n, R. Carbonell n & O. Rojas n

MeSH headings : Binding Sites; Biofouling / prevention & control; Humans; Immunoglobulin G / chemistry; Particle Size; Peptides / chemical synthesis; Peptides / chemistry; Polymers / chemistry; Quartz Crystal Microbalance Techniques; Surface Plasmon Resonance; Surface Properties
TL;DR: The effect of copolymer molecular composition and analyte concentration was elucidated in order to design systems based on immobilized peptides for high signal-to-noise response and detection limits that meet the requirements for IgG biosensing in fluid matrixes. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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