Works (1)
Updated: April 11th, 2023 10:13
2022 article
Phosphorylation-dependent proteome of Marcks in ependyma during aging and behavioral homeostasis in the mouse forebrain
Muthusamy, N., Williams, T. I., O'Toole, R., Brudvig, J. J., Adler, K. B., Weimer, J. M., … Ghashghaei, H. T. (2022, January 24). GEROSCIENCE, Vol. 1.
Contributors: n, T. Williams n , R. O’Toole *, J. Brudvig *, K. Adler n, J. Weimer *, D. Muddiman n , H. Ghashghaei n
author keywords: Aging; Behavior; Clca3; Ependymal cells; Forebrain; Marcks; Mass spectrometry; Neuroinflammation
MeSH headings : Mice; Animals; Phosphorylation; Ependyma / metabolism; Intracellular Signaling Peptides and Proteins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate / metabolism; Proteome / metabolism; Membrane Proteins / metabolism; Protein Kinase C / metabolism; Homeostasis; Prosencephalon / metabolism; Mammals / metabolism
TL;DR:
This study provides first line of evidence for potential mechanisms that may mediate differential Marcks functions in young and old ECs, and their effect on forebrain homeostasis during aging.
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Added: January 31, 2022
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