Works (6)

Updated: March 9th, 2024 05:00

2023 journal article

3-Component Approach to 1,5-Dihydro-2H-pyrrol-2-one Heterocycles

ORGANIC SYNTHESES, 100, 418-+.

By: N. Massaro* & J. Pierce

Sources: Web Of Science, ORCID
Added: March 4, 2024

2022 journal article

Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture

ACTA BIOMATERIALIA, 138, 208–217.

By: C. Moody n, A. Brown n, N. Massaro n, A. Patel n, P. Agarwalla n, A. Simpson n, A. Brown n, H. Zheng n, J. Pierce n, Y. Brudno n

author keywords: Alginate; Click chemistry; Bioconjugation; Ionic cross-linking; Drug capture
Sources: Web Of Science, ORCID
Added: October 31, 2021

2022 journal article

Tissue-reactive drugs enable materials-free local depots

JOURNAL OF CONTROLLED RELEASE, 343, 142–151.

By: S. Pandit n, S. Palvai n, N. Massaro n, J. Pierce n & Y. Brudno n

author keywords: Sustained release; Materials-free delivery; Paclitaxel; Pancreatic cancer; Extracellular matrix; N-hydroxysuccinimide ester
MeSH headings : Animals; Cell Line, Tumor; Drug Delivery Systems; Drug Liberation; Hydrogels; Mice; Paclitaxel; Pancreatic Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: May 2, 2022

2021 review

Leveraging Marine Natural Products as a Platform to Tackle Bacterial Resistance and Persistence

[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 54(8), 1866–1877.

By: M. Valdes-Pena n, N. Massaro n, Y. Lin n & J. Pierce n

MeSH headings : Alkaloids / chemical synthesis; Alkaloids / pharmacology; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biological Products / chemical synthesis; Biological Products / chemistry; Biological Products / pharmacology; Drug Resistance, Multiple, Bacterial / drug effects; Guanidine / analogs & derivatives; Guanidine / chemical synthesis; Guanidine / pharmacology; Guanidines / chemical synthesis; Guanidines / pharmacology; Microbial Sensitivity Tests; Oxazolidinones / chemical synthesis; Oxazolidinones / pharmacology; Staphylococcus aureus / drug effects; Staphylococcus aureus / physiology; Stereoisomerism; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: March 19, 2021

2021 journal article

Rapid synthesis of the core scaffold of crinane and haemanthamine through a multi-component approach

TETRAHEDRON LETTERS, 75.

By: N. Massaro n & J. Pierce n

author keywords: Amaryllidaceae alkaloids; Heterocycles; Multicomponent; Natural products; Total synthesis
Sources: Web Of Science, ORCID
Added: May 25, 2021

2020 journal article

Stereoselective, Multicomponent Approach to Quaternary Substituted Hydroindole Scaffolds

ORGANIC LETTERS, 22(13), 5079–5084.

By: N. Massaro n & J. Pierce n

MeSH headings : Amaryllidaceae Alkaloids / chemistry; Indoles / chemical synthesis; Indoles / chemistry; Stereoisomerism
Sources: Web Of Science, ORCID
Added: August 3, 2020

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