Nicola V. L. Serao

Works (13)

Updated: April 15th, 2025 10:47

2020 article

Beef cattle that respond differently to fescue toxicosis have distinct gastrointestinal tract microbiota

Koester, L. R., Poole, D. H., Serão, N. V. L., & Schmitz-Esser, S. (2020, July 23). PLoS ONE, Vol. 15.

By: L. Koester *, D. Poole n , N. Serão* & S. Schmitz-Esser *

MeSH headings : Animals; Ascomycota / isolation & purification; Ascomycota / metabolism; Cattle; Discriminant Analysis; Epichloe / metabolism; Ergot Alkaloids / analysis; Ergot Alkaloids / toxicity; Feces / microbiology; Gastrointestinal Microbiome / drug effects; Lolium / microbiology; Neocallimastigales / isolation & purification; Neocallimastigales / metabolism; Symbiosis; Toxins, Biological / analysis; Toxins, Biological / toxicity
topics (OpenAlex): Plant and fungal interactions; Fungal Biology and Applications; Plant Toxicity and Pharmacological Properties
TL;DR: This study reveals significantly (P<0.05) different bacterial and fungal microbiota between HT and LT cattle, and indicates that fungal phylotypes may be important for an animal’s response to fescue toxicosis, and found that fungan phylotypes affiliating to the Neocallimastigaceae were consistently more abundant in the HT cattle. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020

2020 article

Evaluation of Resistance to Fescue Toxicosis in Purebred Angus Cattle Utilizing Animal Performance and Cytokine Response

Poole, D. H., Mayberry, K. J., Newsome, M. K., Poole, R. K., Galliou, J. M., Khanal, P., … Serão, N. V. L. (2020, December 14). Toxins, Vol. 12.

By: D. Poole n , K. Mayberry n, M. Newsome n, R. Poole  n, J. Galliou n, P. Khanal n, M. Poore n, N. Serão n

author keywords: fescue toxicosis; genetic tolerance; cytokines; cow productivity
MeSH headings : Animal Feed / analysis; Animal Feed / toxicity; Animals; Behavior, Animal / drug effects; Behavior, Animal / physiology; Cattle; Cattle Diseases / chemically induced; Cattle Diseases / metabolism; Cattle Diseases / microbiology; Cytokines / metabolism; Ergot Alkaloids / analysis; Ergot Alkaloids / toxicity; Herbivory / drug effects; Herbivory / physiology; Poaceae / microbiology; Poaceae / toxicity
topics (OpenAlex): Plant and fungal interactions; Turfgrass Adaptation and Management; Botanical Research and Chemistry
TL;DR: Findings from this study support the proposed fescue toxicosis selection method, could accurately distinguish between tolerant and susceptible animals based on the performance parameters in cattle chronically exposed to ergot alkaloids, and provides evidence to warrant additional analysis to examine the impact of ergotAlkaloids on immune responsiveness in cattle experiencing fescues toxicosis. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021

2020 article

Evaluation of a commercial genetic test for fescue toxicosis in pregnant Angus beef cattle1

Galliou, J. M., Khanal, P., Mayberry, K., Poore, M. H., Poole, D. H., & Serão, N. V. L. (2020, October 1). Translational Animal Science, Vol. 4.

By: J. Galliou n, P. Khanal n, K. Mayberry n, M. Poore n, D. Poole n  & N. Serão n

author keywords: Bos taurus; Epichloe coenophiala; fescue toxicity; host genetics; T-Snip test
topics (OpenAlex): Plant and fungal interactions; Turfgrass Adaptation and Management; Botanical Research and Chemistry
TL;DR: Results indicate that the T-Snip test may be predictive of cow performance (aBWd, aBCSd, and adjWW) in an endophyte-infected tall fescue environment. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021

2020 article

PSVII-8 miRNAs explain the variation in muscle and blood transcriptomes of beef calves born from dams with or without energy restriction during late gestation

Carvalho, E. B., Sanglard, L. P., Nascimento Moysés, Moriel, P., Sommer, J., Merrill, M., … Serão, N. (2020, November 2). Journal of Animal Science, Vol. 98, pp. 165–165.

By: E. Carvalho *, L. Sanglard *, M. Nascimento*, P. Moriel*, J. Sommer n, M. Merrill n , M. Poore n, M. Duarte* , N. Serão*

author keywords: Fetal-programming; maternal nutrition; post-transcriptional regulation
topics (OpenAlex): Cancer-related molecular mechanisms research; MicroRNA in disease regulation; Circular RNAs in diseases
TL;DR: Using RNA-seq data, a large amount of the variation of DEGs was identified, with the identification of important miRNAs related to muscle development and immune system and MiR-21 regulates immune system by different pathways. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 8, 2021

2019 article

155 Evaluation of cytokine response as an indicator of genetic resistance to fescue toxicosis in purebred Angus cattle

Mayberry, K., Poole, R. K., Newsome, M. K. A., Khanal, P., Poore, M. H., Serao, N. V. L., & Poole, D. H. (2019, July 1). Journal of Animal Science, Vol. 97, pp. 45–46.

By: K. Mayberry n, R. Poole  n, M. Newsome n, P. Khanal n, M. Poore n, N. Serao*, D. Poole n 

author keywords: fescue toxicosis; genetic tolerance; cytokines
topics (OpenAlex): Plant and fungal interactions
TL;DR: Evaluating the cytokine response of cows deemed either tolerant or susceptible to endophyte-infected fescue found greater concentrations of GASP-1, VEGF-A, and IL-4 in tolerant compared to susceptible cattle may mitigate the detrimental effects of fescUE toxicosis, including suppressed PRL and vasoconstriction, leading to improved animal performance in a fescues environment. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 article

Genetic analysis of reproductive performance in sows during porcine reproductive and respiratory syndrome (PRRS) and porcine epidemic diarrhea (PED) outbreaks

Scanlan, C. L., Putz, A. M., Gray, K. A., & Serão, N. V. L. (2019, February 28). Journal of Animal Science and Biotechnology/Journal of Animal Science and Biotechnology.

By: C. Scanlan n, A. Putz *, K. Gray* & N. Serão n

author keywords: Genetic evaluation; Porcine epidemic diarrhea; Porcine reproductive and respiratory syndrome; Reproductive performance; Swine
topics (OpenAlex): Animal Virus Infections Studies; Viral gastroenteritis research and epidemiology; Animal Disease Management and Epidemiology
TL;DR: Results indicate that selection for improved performance during PRRS and PED in commercial sows is possible and would not negatively impact performance in Clean environments. (via Semantic Scholar)
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Source: Web Of Science
Added: March 18, 2019

2019 article

PSIII-3 Genes and functions associated with tolerance to fescue toxicosis in Angus cows

Khanal, P., Sanglard, L. P., Mayberry, K., Sommer, J., Poore, M. H., Poole, D. H., & Serão, N. V. L. (2019, July 1). Journal of Animal Science, Vol. 97, pp. 167–167.

By: P. Khanal n, L. Sanglard*, K. Mayberry n, J. Sommer n, M. Poore n, D. Poole n , N. Serão*

author keywords: fescue toxicosis; differentially expressed genes; tolerance
topics (OpenAlex): Plant and fungal interactions; Mycotoxins in Agriculture and Food; Turfgrass Adaptation and Management
TL;DR: Enrichment analysis showed that DEG between genetic groups have general functions, such as metabolic, biosynthetic, and catabolic processes, as well as DNA and RNA-related functions,such as translation, transcription, and repair. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2018 article

110 Evaluation of Angus Calf Performance Based on Dams Tolerance or Susceptibility to Fescue Toxicosis.

Mayberry, K., Khanal, P., Poore, M. H., Serão, N. V. L., & Poole, D. H. (2018, March 1). Journal of Animal Science, Vol. 96, pp. 55–55.

By: K. Mayberry n, P. Khanal n, M. Poore n, N. Serão* & D. Poole n 

author keywords: calf performance; cow productivity; fescue toxicosis
topics (OpenAlex): Plant and fungal interactions; Plant Pathogens and Fungal Diseases
Sources: Web Of Science, NC State University Libraries
Added: November 26, 2018

2017 article

Effect of a major quantitative trait locus for porcine reproductive and respiratory syndrome (PRRS) resistance on response to coinfection with PRRS virus and porcine circovirus type 2b (PCV2b) in commercial pigs, with or without prior vaccination for PRRS1

Dunkelberger, J. R., Serão, N. V. L., Niederwerder, M. C., Kerrigan, M. A., Lunney, J. K., Rowland, R. R. R., & Dekkers, J. C. M. (2017, February 1). Journal of Animal Science.

By: J. Dunkelberger*, N. Serão n, M. Niederwerder *, M. Kerrigan*, J. Lunney *, R. Rowland*, J. Dekkers *

author keywords: pigs; porcine circovirus type 2; porcine reproductive and respiratory syndrome; swine; WUR10000125
MeSH headings : Animals; Circoviridae Infections / complications; Circoviridae Infections / immunology; Circoviridae Infections / veterinary; Circovirus / immunology; Coinfection / veterinary; Female; Genotype; Kansas; Male; Polymorphism, Single Nucleotide / genetics; Porcine Reproductive and Respiratory Syndrome / genetics; Porcine Reproductive and Respiratory Syndrome / immunology; Porcine respiratory and reproductive syndrome virus / immunology; Quantitative Trait Loci / genetics; Swine; Swine Diseases / genetics; Swine Diseases / immunology; Swine Diseases / virology; Vaccination / veterinary; Viral Load / veterinary; Viremia
topics (OpenAlex): Animal Virus Infections Studies; Viral gastroenteritis research and epidemiology; Plant Virus Research Studies
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 article

Genomewide association of piglet responses to infection with one of two porcine reproductive and respiratory syndrome virus isolates1

Waide, E. H., Tuggle, C. K., Serão, N. V. L., Schroyen, M., Hess, A., Rowland, R. R. R., … Dekkers, J. C. M. (2017, January 1). Journal of Animal Science.

By: E. Waide*, C. Tuggle *, N. Serão n, M. Schroyen *, A. Hess *, R. Rowland*, J. Lunney *, G. Plastow *, J. Dekkers *

author keywords: function analysis genomewide association study; genetics; genomewide association study; genomics; pig; porcine reproductive and respiratory syndrome virus
MeSH headings : Animals; Bayes Theorem; Genome; Genome-Wide Association Study; Genomics; Genotype; Phenotype; Porcine Reproductive and Respiratory Syndrome / genetics; Porcine Reproductive and Respiratory Syndrome / virology; Porcine respiratory and reproductive syndrome virus / classification; Swine; Viral Load
topics (OpenAlex): Animal Virus Infections Studies; Genetic and phenotypic traits in livestock; Genetic Mapping and Diversity in Plants and Animals
TL;DR: Genomic regions whose associations with VL or WG interacted with either PRRSV isolate or with genotype at the SSC4 QTL are identified, suggesting that host responses to these 2 isolates are affected by the actions of many genes that function together in similar biological processes. (via Semantic Scholar)
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Added: August 6, 2018

2017 article

Technical Note: A comparison among adipogenic induction protocols for dedifferentiated fat (DFAT) cells obtained from subcutaneous fat of pigs

Bueno, R., Campos, C. F., Veroneze, R., Silva, W., Sanglard, L. M. P., Alcantara, L., … Guimarães, S. E. F. (2017, March 15). Livestock Science.

By: R. Bueno *, C. Campos *, R. Veroneze *, W. Silva *, L. Sanglard *, L. Alcantara*, N. Serão n, G. Hausman * ...

author keywords: Adipogenesis; dipocyte; IBMX; Insulin
topics (OpenAlex): Adipose Tissue and Metabolism; Adipokines, Inflammation, and Metabolic Diseases; Fatty Acid Research and Health
TL;DR: The results suggest that neither insulin nor IBMX are required to accelerate redifferentiation process of pig-derived DFAT cells. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2016 article

Genetic and genomic basis of antibody response to porcine reproductive and respiratory syndrome (PRRS) in gilts and sows

Serão, N. V. L., Kemp, R. A., Mote, B. E., Willson, P., Harding, J. C. S., Bishop, S. C., … Dekkers, J. C. M. (2016, July 14). Genetics Selection Evolution.

By: N. Serão n, R. Kemp, B. Mote *, P. Willson*, J. Harding *, S. Bishop*, G. Plastow *, J. Dekkers *

author keywords: Disease resistance; Disease resilience; Genomic prediction; Genomic selection; PRRSV; Vaccination
MeSH headings : Animals; Antibodies, Viral / blood; Antibody Formation / genetics; Breeding; Female; Genome-Wide Association Study; Genomics / methods; Genotype; Phenotype; Polymorphism, Single Nucleotide; Porcine Reproductive and Respiratory Syndrome / genetics; Porcine Reproductive and Respiratory Syndrome / immunology; Quantitative Trait Loci; Sus scrofa / genetics; Sus scrofa / virology; Swine
topics (OpenAlex): Genetic and phenotypic traits in livestock; Genetic Mapping and Diversity in Plants and Animals; Animal Virus Infections Studies
TL;DR: Moderate genomic prediction accuracies can be obtained for PRRS antibody response using SNPs located within two major QTL on SSC7, while the rest of the genome showed limited predictive ability. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 article

Molecular Factors Underlying the Deposition of Intramuscular Fat and Collagen in Skeletal Muscle of Nellore and Angus Cattle

Martins, T. S., Sanglard, L. M. P., Silva, W., Chizzotti, M. L., Rennó, L. N., Serão, N. V. L., … Duarte, M. S. (2015, October 5). PLoS ONE.

By: T. Martins *, L. Sanglard *, W. Silva *, M. Chizzotti *, L. Rennó *, N. Serão n, F. Silva *, S. Guimarães * ...

MeSH headings : Acetyl-CoA Carboxylase / metabolism; Adipogenesis / physiology; Adipose Tissue / metabolism; Animals; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Cattle; Collagen / metabolism; Muscle, Skeletal / metabolism; PPAR gamma / metabolism; Species Specificity; fas Receptor / metabolism
topics (OpenAlex): Muscle Physiology and Disorders; Adipose Tissue and Metabolism; Meat and Animal Product Quality
TL;DR: Difference in intramuscular fat content is associated with a slightly enhanced adipogenesis in skeletal muscle of Angus compared to Nellore cattle, while no difference in fibrogenesis is demonstrated. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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