Philip Awadalla

Works (12)

Updated: July 25th, 2023 21:15
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2011 journal article

A population genetic approach to mapping neurological disorder genes using deep resequencing

PLoS Genetics, 7(2).

By: R. Myers, F. Casals, J. Gauthier, F. Hamdan, J. Keebler, A. Boyko, C. Bustamante, A. Piton ...

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs

Nature Genetics, 42(3), 268–113.

By: J. Mu, R. Myers, H. Jiang, S. Liu, S. Ricklefs, M. Waisberg, K. Chotivanich, P. Wilairatana ...

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Selection shapes malaria genomes and drives divergence between pathogens infecting hominids versus rodents

BMC Evolutionary Biology, 8.

By: F. Prugnolle, K. Mcgee, J. Keebler & P. Awadalla

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome

NATURE GENETICS, 39(1), 126–130.

By: J. Mu *, P. Awadalla n, J. Duan*, K. McGee n, J. Keebler n, K. Seydel *, G. McVean *, X. Su *

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Animals; Antigens, Protozoan / genetics; Antigens, Protozoan / isolation & purification; Antigens, Protozoan / metabolism; Cell-Free System / metabolism; Chromosome Mapping; Drug Delivery Systems; Drug Design; Drug Resistance / genetics; Genetic Variation; Genome, Protozoan; Humans; Immune Sera / chemistry; Malaria Vaccines / immunology; Malaria, Falciparum / immunology; Malaria, Falciparum / parasitology; Plasmodium falciparum / genetics; Plasmodium falciparum / immunology
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 155(2), 103–112.

By: J. Bockhorst*, F. Lu *, J. Janes*, J. Keebler n, B. Gamain *, P. Awadalla n, X. Su *, R. Samudrala *, N. Jojica, J. Smith *

co-author countries: France 🇫🇷 United States of America 🇺🇸
author keywords: antigenic variation; malaria; Plasmodium falciparum; var genes
MeSH headings : Animals; Antigens, Protozoan / chemistry; Antigens, Protozoan / genetics; Antigens, Protozoan / immunology; Computational Biology / methods; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; Female; Geography; Humans; Malaria / immunology; Malaria / parasitology; Malaria Vaccines / immunology; Models, Molecular; Molecular Sequence Data; Phylogeny; Plasmodium falciparum / genetics; Plasmodium falciparum / isolation & purification; Polymorphism, Genetic; Pregnancy; Pregnancy Complications, Parasitic / immunology; Pregnancy Complications, Parasitic / prevention & control; Protein Structure, Tertiary; Selection, Genetic; Sequence Analysis, DNA; Sequence Homology, Amino Acid
Source: Web Of Science
Added: August 6, 2018

2006 journal article

A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection

BMC Genomics, 7.

By: M. Jackson, A. Watt, P. Gautier, D. Gilchrist, J. Driehaus, G. Graham, J. Keebler, F. Prugnolle, P. Awadalla, L. Forrester

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Global genetic diversity and evolution of var genes associated with placental and severe childhood malaria

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 148(2), 169–180.

By: A. Trimnell*, S. Kraemer*, S. Mukherjee*, D. Phippard*, J. Janes*, E. Flamoe*, X. Su*, P. Awadalla n, J. Smith *

co-author countries: United States of America 🇺🇸
author keywords: malaria; Plasmodium falciparum; antigenic variation; var genes
MeSH headings : Amino Acid Sequence; Animals; Antigenic Variation / genetics; Child; Evolution, Molecular; Female; Genes, Protozoan; Genetic Variation; Humans; Malaria, Falciparum / parasitology; Malaria, Falciparum / physiopathology; Molecular Sequence Data; Placenta / parasitology; Placenta Diseases / parasitology; Plasmodium falciparum / genetics; Plasmodium falciparum / immunology; Pregnancy; Pregnancy Complications, Parasitic / parasitology; Sequence Analysis, DNA; Severity of Illness Index
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Phenotypic variation and natural selection at Catsup, a pleiotropic quantitative trait gene in Drosphila

CURRENT BIOLOGY, 16(9), 912–919.

By: M. Carbone n, K. Jordan n, R. Lyman n, S. Harbison  n, J. Leips*, T. Morgan n, M. DeLuca n, P. Awadalla n, T. Mackay n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Catecholamines / metabolism; Drosophila / anatomy & histology; Drosophila / genetics; Drosophila Proteins / chemistry; Drosophila Proteins / genetics; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Female; Genetic Variation; Genotype; Longevity / genetics; Male; Molecular Sequence Data; Motor Activity / genetics; Phenotype; Quantitative Trait Loci; Quantitative Trait, Heritable; Selection, Genetic
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Recombination hotspots and population structure in Plasmodium falciparum

PLOS BIOLOGY, 3(10), 1734–1741.

By: J. Mu *, P. Awadalla n, J. Duan*, K. McGee n, D. Joy*, G. McVean *, X. Su *

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Africa; Animals; Asia, Southeastern; Central America; Drug Resistance; Genetics, Population; Linkage Disequilibrium / genetics; Papua New Guinea; Plasmodium falciparum / genetics; Polymorphism, Single Nucleotide; Recombination, Genetic / physiology; South America
Source: Web Of Science
Added: August 6, 2018

2004 article

Darwinian selection on a selfing locus (Retracted Article. See vol 320, pg 176, 2008)

Shimizu, K. K., Cork, J. M., Caicedo, A. L., Mays, C. A., Moore, R. C., Olsen, K. M., … Purugganan, M. D. (2004, December 17). SCIENCE, Vol. 306, pp. 2081–2084.

By: K. Shimizu n, J. Cork n, A. Caicedo n, C. Mays n, R. Moore n, K. Olsen n, S. Ruzsa n, G. Coop  n ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Alleles; Arabidopsis / genetics; Arabidopsis / physiology; Biological Evolution; Chromosome Mapping; Climate; DNA, Intergenic; Genes, Plant; Genetic Variation; Genome, Plant; Geography; Haplotypes; Likelihood Functions; Molecular Sequence Data; Open Reading Frames; Phylogeny; Plant Proteins; Pollen; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protein Kinases / genetics; Protein Kinases / physiology; Pseudogenes; Recombination, Genetic; Selection, Genetic; Time
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus

PLoS Biology, 2(6), 839–848.

By: D. Barbash *, P. Awadalla n & A. Tarone*

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; DNA Primers; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Genetics, Population; Hybridization, Genetic / genetics; Male; Models, Genetic; Molecular Sequence Data; Phylogeny; Reproduction / physiology; Reverse Transcriptase Polymerase Chain Reaction; Selection, Genetic; Sequence Alignment; Sequence Analysis, DNA; Species Specificity; Transgenes / genetics
Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Low linkage disequilibrium indicative of recombination in foot-and-mouth disease virus gene sequence alignments

JOURNAL OF GENERAL VIROLOGY, 85, 1095–1100.

By: D. Haydon *, A. Bastos * & P. Awadalla n

co-author countries: Canada 🇨🇦 United States of America 🇺🇸 South Africa 🇿🇦
MeSH headings : Capsid Proteins / genetics; Foot-and-Mouth Disease Virus / genetics; Genes, Viral; Linkage Disequilibrium; Recombination, Genetic; Sequence Analysis, RNA / methods
Source: Web Of Science
Added: August 6, 2018