Petra Bizikova

Works (49)

Updated: April 5th, 2024 05:50

2023 journal article

Erosive and ulcerative stomatitis in dogs and cats: which immune-mediated diseases to consider?

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 261, S48–S57.

By: P. Bizikova n, K. Linder n & J. Anderson*

TL;DR: Some immune-mediated diseases such as severe adverse drug reactions, lupus diseases, canine uveodermatological syndrome, and vasculitis, may or may not involve the oral cavity, and often nonoral clinical manifestations are more diagnostic. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 11, 2023

2023 article

Histopathological characterisation of trunk-dominant canine pemphigus foliaceus, and comparison with classic facial and insecticide-triggered forms

Gedon, N. K. Y., Bizikova, P., Olivry, T., Mendoza-Kuznetsova, E., Oberkirchner, U., Robertson, J. B., & Linder, K. E. (2023, June 14). VETERINARY DERMATOLOGY, Vol. 6.

By: N. Gedon n, P. Bizikova n, T. Olivry n, E. Mendoza-Kuznetsova*, U. Oberkirchner*, J. Robertson n, K. Linder n

author keywords: acantholysis; autoimmune diseases; dog diseases; pathological findings; pemphigus; skin diseases
TL;DR: Trunk-dominant PF and other canine PF variants are histologically similar, which indicates shared pathomechanisms, and results indicate that diagnostic biopsies cannot differentiate between these PF variants in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: July 3, 2023

2023 review

Spontaneous autoimmune subepidermal blistering diseases in animals: a comprehensive review

[Review of ]. BMC VETERINARY RESEARCH, 19(1).

By: P. Bizikova n, T. Olivry n, K. Linder n & J. Rybnicek

author keywords: Autoimmune; Skin; Pemphigoid; Dog; Cat; Blister
MeSH headings : Humans; Animals; Dogs; Skin; Pemphigus / veterinary; Epidermis; Autoantibodies; Breeding; Dog Diseases / diagnosis
TL;DR: Canine AISBDs are the best characterised, particularly the more common variants such as mucous membrane pemphigoid (48%), epidermolysis bullosa acquisita (EBA) (26%), and bullous pem PHD (10%), and shorter descriptions of variants in other species are provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: February 27, 2023

2022 article

Long-term effects of ciclosporin and oclacitinib on mediators of tolerance, regulatory T-cells, IL-10 and TGF-beta, in dogs with atopic dermatitis

Herrmann, I., Mamo, L. B., Holmes, J., Mohammed, J. P., Murphy, K. M., & Bizikova, P. (2022, December 8). VETERINARY DERMATOLOGY.

By: I. Herrmann n, L. Mamo n, J. Holmes n, J. Mohammed n, K. Murphy n & P. Bizikova n

author keywords: canine atopic dermatitis; ciclosporin; oclacitinib; T regulatory cell
MeSH headings : Dogs; Animals; Cyclosporine / therapeutic use; T-Lymphocytes, Regulatory; Interleukin-10; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Transforming Growth Factor beta1 / therapeutic use; Transforming Growth Factor beta / therapeutic use; Immune Tolerance; Dog Diseases / drug therapy
TL;DR: Lower Treg cell percentages in the CSA-treated dogs suggest an impact of this drug on this cell population; however, it does not necessarily mean that it diminishes tolerance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: January 3, 2023

2022 article

Trunk-dominant and classic facial pemphigus foliaceus in dogs - comparison of anti-desmocollin-1 and anti-desmoglein-1 autoantibodies and clinical presentations

Bizikova, P., Linder, K. E., & Mamo, L. B. (2022, June 7). VETERINARY DERMATOLOGY.

By: P. Bizikova n, K. Linder n & L. Mamo n

MeSH headings : Animals; Autoantibodies; Desmoglein 1; Dog Diseases; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin G; Pemphigus / diagnosis; Pemphigus / veterinary
TL;DR: Footpad involvement and grouped/polycyclic lesion organisation were identified as features of both PF phenotypes, and not of SP, and the ability to detect anti-DSC1 IgG is lower in trunk-dominant PF, yet despite the lower sensitivity, the positive predictive value and accuracy of this particular anti- DSC1 igG test are high. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 20, 2022

2021 article

Bullous amyloidosis in a horse: first description in veterinary medicine

Fussell, D., Bizikova, P., Breuhaus, B., Harris, R. A., Moore, A. R., Chen, L., & Linder, K. E. (2021, June 13). VETERINARY DERMATOLOGY, Vol. 6.

MeSH headings : Amyloid; Amyloidosis / diagnosis; Amyloidosis / veterinary; Animals; Blister / veterinary; Female; Horse Diseases / diagnosis; Horses; Mucous Membrane; Skin
TL;DR: Bullous amyloidosis is a novel disease of the horse and a newly recognised differential for bullous disease, for which the haemorrhagic nature of bullae, scarring and deep secondary ulcers are considered clinical clues to the condition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: June 21, 2021

2021 journal article

Canine junctional epidermolysis bullosa due to a novel mutation in LAMA3 with severe upper respiratory involvement

VETERINARY DERMATOLOGY, 32(4), 379-+.

By: I. Herrmann n, K. Linder n, K. Meurs n, S. Friedenberg*, J. Cullen*, N. Olby n, P. Bizikova n

MeSH headings : Animals; Australia; Cattle; Dog Diseases / genetics; Dogs; Epidermolysis Bullosa, Junctional / genetics; Epidermolysis Bullosa, Junctional / veterinary; Laminin / genetics; Mutation, Missense; Nail Diseases / genetics; Nail Diseases / veterinary
TL;DR: A novel variant in LAMA3 caused a generalized and severe phenotype of JEB with an unique clinical presentation of upper airway obstruction in a litter of puppies with severe upper respiratory involvement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: July 19, 2021

2021 journal article

Feline allergic diseases: introduction and proposed nomenclature

VETERINARY DERMATOLOGY, 32(1), 8-+.

By: R. Halliwell*, C. Pucheu-Haston*, T. Olivry n, C. Prost*, H. Jackson, F. Banovic*, T. Nuttall*, D. Santoro*, P. Bizikova n, R. Mueller*

MeSH headings : Allergens; Animals; Cat Diseases / classification; Cat Diseases / immunology; Cat Diseases / pathology; Cats; Dermatitis, Atopic / classification; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dogs; Food Hypersensitivity / veterinary; Humans; Skin / pathology; Terminology as Topic
Sources: Web Of Science, ORCID
Added: January 20, 2021

2021 journal article

Pathology in Practice

Journal of the American Veterinary Medical Association, 258(9), 961–964.

By: A. DiDomenico n, A. Fowler n, C. Horne n, P. Bizikova n, L. Schnabel n & D. Stowe n

MeSH headings : Animals
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: June 10, 2021

2021 review

Treatment of the feline atopic syndrome - a systematic review

[Review of ]. VETERINARY DERMATOLOGY, 32(1), 43-+.

By: R. Mueller*, T. Nuttall*, C. Prost*, B. Schulz* & P. Bizikova n

MeSH headings : Allergens; Animals; Cat Diseases / therapy; Cats; Cyclosporine; Dermatitis, Atopic / therapy; Dermatitis, Atopic / veterinary; Desensitization, Immunologic / veterinary; Glucocorticoids / therapeutic use; Immunotherapy / veterinary; Retrospective Studies; Syndrome
TL;DR: Evidence supported low-to-moderate efficacy of mesenchymal stem cells, inhaled lidocaine and oclacitinib as treatments for feline asthma, and good evidence for the efficacy of systemic glucocorticoids and ciclosporin was found. (via Semantic Scholar)
Source: Web Of Science
Added: February 8, 2021

2020 journal article

Cutaneous polyautoimmunity in two unrelated dogs: pemphigus foliaceus and generalized discoid lupus erythematosus

VETERINARY DERMATOLOGY, 31(4), 325-+.

By: B. Levy n, K. Linder n, L. Mamo n, I. Herrmann n & P. Bizikova n

MeSH headings : Administration, Cutaneous; Animals; Comorbidity; Cyclosporine / therapeutic use; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Lupus Erythematosus, Discoid / diagnosis; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / veterinary; Pemphigus / diagnosis; Pemphigus / drug therapy; Pemphigus / veterinary; Skin / pathology
TL;DR: Cutaneous polyautoimmunity can occur in the dog and overlapping clinical features may present diagnostic and/or therapeutic challenges. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 18, 2020

2020 journal article

Detection of circulating anti-keratinocyte autoantibodies in feline pemphigus foliaceus

VETERINARY DERMATOLOGY, 31(5), 378-+.

By: B. Levy n, L. Mamo n & P. Bizikova n

MeSH headings : Animals; Autoantibodies / blood; Cat Diseases; Cats; Desmoglein 1; Dog Diseases; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Keratinocytes; Pemphigus / veterinary
TL;DR: The detection of positive immunostaining on buccal mucosal tissue, in addition to the footpad, suggests that the major target antigen of feline PF differs from that identified in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 27, 2020

2020 journal article

Detection of circulating anti-retinal antibodies in dogs with sudden acquired retinal degeneration syndrome using indirect immunofluorescence: A case control study

EXPERIMENTAL EYE RESEARCH, 193.

By: F. Mowat n, J. Avelino n, A. Bowyer n, V. Parslow n, H. Westermeyer n, M. Foster n, J. Fogle n, P. Bizikova n

author keywords: SARDS; Dog; Retina; Immune-mediated; IgG; IgM
MeSH headings : Animals; Autoantibodies / immunology; Blotting, Western; Case-Control Studies; Disease Models, Animal; Dogs; Fluorescent Antibody Technique, Indirect / methods; Retina / immunology; Retina / metabolism; Retina / pathology; Retinal Degeneration / diagnosis; Retinal Degeneration / immunology; Retinal Degeneration / metabolism; Syndrome
TL;DR: Despite having decreased serum IgG compared with healthy controls, circulating IgG in dogs with SARDS binds photoreceptor outer segments to a greater extent than matched healthy controls. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: April 20, 2020

2020 journal article

Efficacy of a Bruton's Tyrosine Kinase Inhibitor (PRN-473) in the treatment of canine pemphigus foliaceus

VETERINARY DERMATOLOGY, 31(4), 291-+.

By: E. Goodale*, K. Varjonen*, C. Outerbridge*, P. Bizikova*, D. Borjesson n, D. Murrell*, A. Bisconte*, M. Francesco* ...

MeSH headings : Animals; Autoantibodies / blood; Dog Diseases / drug therapy; Dog Diseases / immunology; Dogs; Female; Immunoglobulin G / blood; Male; Pemphigus / drug therapy; Pemphigus / veterinary; Pilot Projects; Protein Kinase Inhibitors / administration & dosage; Protein Kinase Inhibitors / therapeutic use
TL;DR: BTKi monotherapy may have beneficial effects in some cases of cPF and is evaluated with a modified version of a validated human Pemphigus Disease Activity Index (cPDAI). (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 3, 2020

2020 journal article

Immunopathogenesis of canine chronic ulcerative stomatitis

PLOS ONE, 15(1).

By: J. Anderson*, A. Kol*, P. Bizikova n, B. Stapelton*, K. Ford*, A. Villarreal*, R. Jimenez*, D. Vasilatis*, B. Murphy*

MeSH headings : Animals; Chronic Disease; Diagnosis, Differential; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Fluorescent Antibody Technique, Direct; Gingivitis, Necrotizing Ulcerative / diagnosis; Gingivitis, Necrotizing Ulcerative / immunology; Gingivitis, Necrotizing Ulcerative / pathology; Gingivitis, Necrotizing Ulcerative / veterinary; Inflammation / etiology; Leukocytes / pathology; Mouth Mucosa / pathology; Periodontal Diseases / diagnosis
TL;DR: The current study confirms the presence of moderate to large numbers of FoxP3+ T cells and IL17+ cells in all ulcerative stomatitis lesions using confocal immunofluorescence, and contributes to the body of literature regarding leukocyte involvement in canine idiopathic inflammatory disease pathogenesis. (via Semantic Scholar)
Source: Web Of Science
Added: June 29, 2020

2020 journal article

Open trial of Bruton's tyrosine kinase inhibitor (PRN1008) in the treatment of canine pemphigus foliaceus

VETERINARY DERMATOLOGY, 31(5), 410-+.

By: E. Goodale*, S. White*, P. Bizikova n, D. Borjesson*, D. Murrell*, A. Bisconte*, M. Francesco*, R. Hill* ...

MeSH headings : Animals; Autoantibodies; Autoimmune Diseases / veterinary; Desmoglein 1; Dog Diseases / drug therapy; Dogs; Leukocytes, Mononuclear; Pemphigus / drug therapy; Pemphigus / veterinary; Protein Kinase Inhibitors / therapeutic use
TL;DR: BTKi PRN1008 monotherapy may have some beneficial effects in some cases of Canine pemphigus foliaceus (cPF) and may be suitable for use in clinical practice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 31, 2020

2020 journal article

Rapid response of hyperkeratotic erythema multiforme to oclacitinib in two dogs

VETERINARY DERMATOLOGY, 31(4), 330-+.

By: E. High n, K. Linder n, L. Mamo n, B. Levy n, I. Herrmann n & P. Bizikova n

MeSH headings : Animals; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Dog Diseases / drug therapy; Dogs; Erythema Multiforme / diagnosis; Erythema Multiforme / drug therapy; Erythema Multiforme / veterinary; Female; Pyrimidines / therapeutic use; Skin Diseases / drug therapy; Skin Diseases / veterinary; Sulfonamides / therapeutic use; Treatment Outcome
TL;DR: Oclacitinib could be considered as a fast-acting and effective treatment option for HKEM in dogs with a complete remission of clinical signs observed in 12 and seven weeks in cases 1 and 2. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 8, 2020

2019 review

Feline pemphigus foliaceus: original case series and a comprehensive literature review

[Review of ]. BMC VETERINARY RESEARCH, 15.

By: P. Bizikova n & A. Burrows*

author keywords: Auto-immune skin diseases; Auto-immunity; Feline; Cat; Dermatology; Pemphigus; Skin
MeSH headings : Animals; Cat Diseases / pathology; Cat Diseases / therapy; Cats; Pemphigus / pathology; Pemphigus / therapy; Pemphigus / veterinary; Treatment Outcome
TL;DR: Despite the overall good prognosis cats with PF can be given, owners should be informed and prepared for these circumstances, which may reduce the risk of euthanasia in the case of disease relapse, and improve treatment compliance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: January 28, 2019

2018 journal article

Generalized papillomatosis in three horses associated with a novel equine papillomavirus (EcPV8)

Veterinary Dermatology, 29(1).

By: K. Linder, P. Bizikova, J. Luff, D. Zhou, H. Yuan, B. Breuhaus, E. Nelson, R. Mackay

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Bartonella henselae, Bartonella koehlerae and Rickettsia rickettsii seroconversion and seroreversion in a dog with acute-onset fever, lameness, and lymphadenopathy followed by a protracted disease course

Veterinary Parasitology: Regional Studies and Reports, 7, 19–24.

By: E. Golly n, E. Breitschwerdt n, N. Balakrishnan n, D. Moore* & P. Bizikova n

TL;DR: Following recent tick exposure in Arkansas, a 2-year-old, female spayed Labradoodle was examined because of a one-week history of lethargy and shifting-leg lameness, and therapeutic elimination of all three pathogens was seemingly achieved. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: September 11, 2019

2017 journal article

Endothelial alterations in a canine model of immune thrombocytopenia

Platelets, 30(1), 88–97.

By: D. LeVine n, R. Cianciolo*, K. Linder n, P. Bizikova n, A. Birkenheuer n, M. Brooks*, A. Salous*, S. Nordone n ...

author keywords: Dog; endothelium; ITP
MeSH headings : Animals; Biomarkers; Biopsy; Blood Coagulation; Blood Platelets / metabolism; Blood Platelets / ultrastructure; Disease Models, Animal; Dogs; Endothelium / metabolism; Endothelium / ultrastructure; Flow Cytometry; Lysophospholipids / blood; Male; Platelet Activation; Platelet Count; Purpura, Thrombocytopenic, Idiopathic / blood; Purpura, Thrombocytopenic, Idiopathic / drug therapy; Purpura, Thrombocytopenic, Idiopathic / etiology; Purpura, Thrombocytopenic, Idiopathic / metabolism; Sphingosine / analogs & derivatives; Sphingosine / blood; von Willebrand Factor / metabolism
TL;DR: The results indicate that endothelial damage occurs in the canine ITP model and variability in the degree of endothelialDamage may account for differences in the bleeding phenotype among patients with ITP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: March 18, 2019

2017 journal article

MYCOBACTERIUM INTRACELLULARE INFECTION CAUSING A RETROPERITONEAL MASS IN A BINTURONG (ARCTICTIS BINTURONG)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 48(2), 544–548.

Contributors: L. Adamovicz*, S. Kennedy-Stoskopf*, A. Talley*, J. Cullen*, E. Cohen*, P. Bizikova*, V. Grunkemeyer*

author keywords: Arctictis binturong; binturong; mycobacteriosis; Mycobacterium intracellulare; pyogranuloma
MeSH headings : Animals; Male; Mycobacterium avium Complex / isolation & purification; Mycobacterium avium-intracellulare Infection / pathology; Mycobacterium avium-intracellulare Infection / veterinary; Viverridae
TL;DR: This case represents an unusual presentation of M. intracellulare in a novel species of castrated male binturong with a history of recurrent pyogranulomatous panniculitis, lymphangitis, and dermatitis and acid-fast organisms identified in both the mass and the perineal skin. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

A randomized, double-blinded crossover trial testing the benefit of two hydrolysed poultry-based commercial diets for dogs with spontaneous pruritic chicken allergy

VETERINARY DERMATOLOGY, 27(4), 289–E70.

By: P. Bizikova n & T. Olivry n

Contributors: P. Bizikova n & T. Olivry n

MeSH headings : Animal Feed / analysis; Animals; Chickens; Dermatitis / veterinary; Diet Therapy / veterinary; Dog Diseases / diet therapy; Dogs; Double-Blind Method; Food Hypersensitivity / veterinary; Hydrolysis; Meat / adverse effects; Pruritus / diet therapy; Pruritus / veterinary
TL;DR: The hydrolysed poultry feather diet did not induce pruritus flares in dogs allergic to chicken in contrast to the hydrolysing chicken liver diet that led to pruritis flares in 40% of these dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Molecular confirmation of shampoo as the putative source of Pseudomonas aeruginosa-induced postgrooming furunculosis in a dog

VETERINARY DERMATOLOGY, 27(4), 320–E80.

By: H. Tham n, M. Jacob n & P. Bizikova n

TL;DR: A clinical investigation suggests a link between Pseudomonas-contaminated shampoo and development of postgrooming furunculosis, and underscores the need for hygienic management of shampoos to help limit this disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Mucous membrane pemphigoid in dogs: A retrospective study of 16 new cases

Veterinary Dermatology, 27(5), 376-.

By: H. Tham, T. Olivry, K. Linder & P. Bizikova

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Canine epidermolysis bullosa acquisita: A retrospective study of 20 cases

Veterinary Dermatology, 26(6), 441-.

By: P. Bizikova, K. Linder, J. Wofford, L. Mamo, S. Dunston & T. Olivry

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Dinotefuran/pyriproxyfen/permethrin pemphigus-like drug reaction in three dogs

Veterinary Dermatology, 26(3), 206-.

By: P. Bizikova, K. Moriello, K. Linder & L. Sauber

Source: NC State University Libraries
Added: August 6, 2018

2015 article

Introduction to the review articles by ICADA on the pathogenesis of atopic dermatitis in dogs

Pucheu-Haston, C. M., Eisenschenk, M. N. C., Bizikova, P., Marsella, R., Nuttall, T., & Santoro, D. (2015, April). VETERINARY DERMATOLOGY, Vol. 26, pp. 77–78.

By: C. Pucheu-Haston*, M. Eisenschenk, P. Bizikova n, R. Marsella*, T. Nuttall* & D. Santoro*

MeSH headings : Animals; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dog Diseases / pathology; Dogs
TL;DR: Introduction to the review articles by ICADA on the pathogenesis of atopic dermatitis in dogs' Veterinary Dermatology, vol 26, no. 2, pp. 77-78 is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Oral glucocorticoid pulse therapy for induction of treatment of canine pemphigus foliaceus - a comparative study

Veterinary Dermatology, 26(5), 354-.

By: P. Bizikova & T. Olivry

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Protozoal nodular dermatitis and panniculitis in a Rottweiler puppy caused by Caryospora bigenetica

Veterinary Dermatology, 27(1), 44–e12.

By: H. Tham n, K. Linder n, A. Tucker*, R. Maggi n & P. Bizikova n

MeSH headings : Animals; Anti-Infective Agents / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Eimeriidae / genetics; Eimeriidae / isolation & purification; Female; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / pathology; Skin Diseases, Parasitic / drug therapy; Skin Diseases, Parasitic / parasitology; Skin Diseases, Parasitic / pathology; Skin Diseases, Parasitic / veterinary
TL;DR: This is the first documentation of the treatment and outcome of C. bigenetica cutaneous infection in a dog and although remission of clinical signs can be achieved with combination therapy of clindamycin and TMS, long-term management is challenging and relapses should be anticipated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 review

Review: Clinical and histological manifestations of canine atopic dermatitis

[Review of ]. Veterinary Dermatology, 26(2).

By: P. Bizikova, D. Santoro, R. Marsella, T. Nuttall, M. Eisenschenk & C. Pucheu-Haston

Source: NC State University Libraries
Added: August 6, 2018

2015 review

Review: Innate immunity, lipid metabolism and nutrition in canine atopic dermatitis

[Review of ]. Veterinary Dermatology, 26(2).

By: C. Pucheu-Haston, D. Santoro, P. Bizikova, M. Eisenschenk, R. Marsella & T. Nuttall

Source: NC State University Libraries
Added: August 6, 2018

2015 review

Review: Lymphocytes, cytokines, chemokines and the T-helper 1-T-helper 2 balance in canine atopic dermatitis

[Review of ]. Veterinary Dermatology, 26(2).

By: C. Pucheu-Haston, P. Bizikova, R. Marsella, D. Santoro, T. Nuttall & M. Eisenschenk

Source: NC State University Libraries
Added: August 6, 2018

2015 review

Review: Pathogenesis of canine atopic dermatitis: skin barrier and host-micro-organism interaction

[Review of ]. Veterinary Dermatology, 26(2).

By: D. Santoro, R. Marsella, C. Pucheu-Haston, M. Eisenschenk, T. Nuttall & P. Bizikova

Source: NC State University Libraries
Added: August 6, 2018

2015 review

Review: Role of genetics and the environment in the pathogenesis of canine atopic dermatitis

[Review of ]. Veterinary Dermatology, 26(2).

By: P. Bizikova, C. Pucheu-Haston, M. Eisenschenk, R. Marsella, T. Nuttall & D. Santoro

Source: NC State University Libraries
Added: August 6, 2018

2015 review

Review: The role of antibodies, autoantigens and food allergens in canine atopic dermatitis

[Review of ]. Veterinary Dermatology, 26(2).

By: C. Pucheu-Haston, P. Bizikova, M. Eisenschenk, D. Santoro, T. Nuttall & R. Marsella

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Fipronil-amitraz-S-methoprene-triggered pemphigus foliaceus in 21 dogs: clinical, histological and immunological characteristics

Veterinary Dermatology, 25(2), 103-.

By: P. Bizikova, K. Linder & T. Olivry

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Localized demodicosis due to Demodex cati on the muzzle of two cats treated with inhalant glucocorticoids

Veterinary Dermatology, 25(3), 222-.

By: P. Bizikova

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Serum autoantibody profiles of IgA, IgE and IgM in canine pemphigus foliaceus

VETERINARY DERMATOLOGY, 25(5), 471–E75.

By: P. Bizikova n, T. Olivry n, L. Mamo n & S. Dunston n

Contributors: P. Bizikova n, T. Olivry n, L. Mamo n & S. Dunston n

MeSH headings : Animals; Autoantibodies / blood; Autoantibodies / immunology; Desmocollins / immunology; Desmoglein 1 / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin A / blood; Immunoglobulin A / immunology; Immunoglobulin E / blood; Immunoglobulin E / immunology; Immunoglobulin M / blood; Immunoglobulin M / immunology; Keratinocytes / immunology; Pemphigus / blood; Pemphigus / immunology; Pemphigus / veterinary
TL;DR: It appears that canine PF is aetiologically and immunologically similar to that of the classic human PF, in which the IgG autoantibody response is also the predominant type. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Cowhage can induce itch in the atopic dog

EXPERIMENTAL DERMATOLOGY, 22(6), 435–437.

By: T. Olivry n, P. Bizikova n, J. Paps n, S. Dunston n, E. Lerner* & G. Yosipovitch*

Contributors: T. Olivry n, P. Bizikova n, J. Paps n, S. Dunston n, E. Lerner* & G. Yosipovitch*

author keywords: canine; dog; itch; model; pruritus
MeSH headings : Animals; Dermatitis, Atopic / etiology; Dermatitis, Atopic / physiopathology; Dogs; Hot Temperature; Inflammation; Mucuna / metabolism; Peptide Hydrolases / chemistry; Protein Denaturation; Pruritus / etiology; Pruritus / physiopathology; Random Allocation; Recombinant Proteins / chemistry; Skin / drug effects; Skin Tests / methods
TL;DR: Cowhage spicules, protein‐rich extracts and mucunain can all inducePruritus and inflammation in dogs as in other species, but the inconsistency of provocation is currently a limitation of this challenge type for future studies of pruritus in dogs. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Cloning and establishment of canine desmocollin-1 as a major autoantigen in canine pemphigus foliaceus

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 149(3-4), 197–207.

By: P. Bizikova n, G. Dean*, T. Hashimoto* & T. Olivry n

Contributors: P. Bizikova n, G. Dean*, T. Hashimoto* & T. Olivry n

author keywords: Autoimmunity; Blistering disease; Desmosome; Desmoglein; DSG1
MeSH headings : Amino Acid Sequence; Animals; Autoantigens / immunology; Base Sequence; Blotting, Western / veterinary; Cloning, Molecular; Desmocollins / genetics; Desmocollins / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin G / blood; Immunoglobulin G / immunology; Molecular Sequence Data; Pemphigus / blood; Pemphigus / immunology; Pemphigus / veterinary; RNA, Messenger / chemistry; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction / veterinary; Sequence Alignment; Sequence Analysis, DNA
TL;DR: Findings suggest that DSC1 is a major autoantigen in canine PF (cPF), as proposed in a recent immunomapping study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Deficient plakophilin-1 expression due to a mutation in PKP1 causes ectodermal dysplasia-skin fragility syndrome in Chesapeake Bay Retriever dogs

PLoS One, 7(2).

By: T. Olivry, K. Linder, P. Wang, P. Bizikova, J. Bernstein, S. Dunston, J. Paps, M. Casal

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Validation of a novel epicutaneous delivery system for patch testing of house dust mite-hypersensitive dogs

Veterinary Dermatology, 23(6).

By: T. Olivry, K. Linder, J. Paps, P. Bizikova, S. Dunston, N. Donne, L. Mondoulet

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Immunomapping of desmosomal and nondesmosomal adhesion molecules in healthy canine footpad, haired skin and buccal mucosal epithelia: comparison with canine pemphigus foliaceus serum immunoglobulin G staining patterns

VETERINARY DERMATOLOGY, 22(2), 132–142.

By: P. Bizikova n, K. Linder n & T. Olivry n

Contributors: P. Bizikova n, K. Linder n & T. Olivry n

MeSH headings : Animals; Cell Adhesion Molecules / analysis; Desmosomal Cadherins / analysis; Dog Diseases / blood; Dog Diseases / immunology; Dog Diseases / metabolism; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Foot; Immunoglobulin G / blood; Mouth Mucosa / immunology; Mouth Mucosa / metabolism; Pemphigus / blood; Pemphigus / immunology; Pemphigus / metabolism; Pemphigus / veterinary; Skin / immunology; Skin / metabolism
TL;DR: The immunological heterogeneity of cPF immunoglobulin G autoantibodies is confirmed and the major indirect immunofluorescence staining pattern and the inability of most cPF sera to label the buccal mucosa closely matched that of desmocollin-1. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Metaflumizone-amitraz (Promeris)-associated pustular acantholytic dermatitis in 22 dogs: evidence suggests contact drug-triggered pemphigus foliaceus

VETERINARY DERMATOLOGY, 22(5), 436–448.

By: U. Oberkirchner, K. Linder n, S. Dunston*, P. Bizikova* & T. Olivry n

Contributors: U. Oberkirchner, K. Linder n, S. Dunston*, P. Bizikova* & T. Olivry n

MeSH headings : Administration, Topical; Animals; Apoptosis / drug effects; Apoptosis / physiology; Caspase 3 / metabolism; Dog Diseases / chemically induced; Dog Diseases / drug therapy; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / therapeutic use; Insecticides / administration & dosage; Insecticides / adverse effects; Keratinocytes / enzymology; Male; Pemphigus / chemically induced; Pemphigus / drug therapy; Pemphigus / veterinary; Semicarbazones / administration & dosage; Semicarbazones / adverse effects; Skin / pathology; Toluidines / administration & dosage; Toluidines / adverse effects
TL;DR: PD has the potential of triggering a variant of PF that resembles spontaneously occurring autoimmune PF at clinical, morphological, immunological and treatment outcome levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

A systematic review of the evidence of reduced allergenicity and clinical benefit of food hydrolysates in dogs with cutaneous adverse food reactions

Veterinary Dermatology, 21(1), 31–40.

By: T. Olivry & P. Bizikova

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Clinical and immunological heterogeneity of canine subepidermal blistering dermatoses with anti-laminin-332 (laminin-5) auto-antibodies

Veterinary Dermatology, 21(4), 345–357.

By: T. Olivry, P. Bizikova, S. Dunston, R. Bond, R. Halliwell, A. Loeffler, C. Pucheu-Haston, M. Chen, M. Marinkovich

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Canine cutaneous epitheliotropic T-cell lymphoma with vesiculobullous lesions resembling human bullous mycosis fungoides

Veterinary Dermatology, 20(4), 281–288.

By: P. Bizikova*, K. Linder*, S. Suter*, A. Van Wettere* & T. Olivry*

Contributors: P. Bizikova*, K. Linder*, S. Suter*, A. Van Wettere* & T. Olivry*

MeSH headings : Animals; Dog Diseases / pathology; Dogs; Lymphoma, T-Cell / pathology; Lymphoma, T-Cell / veterinary; Male; Skin Neoplasms / pathology; Skin Neoplasms / veterinary
TL;DR: Clonal rearrangement analysis of antigen receptor genes in samples from skin and lung lesions using primers specific for canine T- cell receptor gamma produced a single-sized amplicon of identical sequence, indicating that both lesions resulted from the expansion of the same neoplastic T-cell population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2008 journal article

Hydroxyzine and cetirizine pharmacokinetics and pharmacodynamics after oral and intravenous administration of hydroxyzine to healthy dogs

VETERINARY DERMATOLOGY, 19(6), 348–357.

By: P. Bizikova*, M. Papich n & T. Olivry*

Contributors: P. Bizikova*, M. Papich n & T. Olivry*

MeSH headings : Administration, Oral; Animals; Cetirizine / blood; Cetirizine / metabolism; Cetirizine / pharmacokinetics; Cross-Over Studies; Dogs; Histamine H1 Antagonists / administration & dosage; Histamine H1 Antagonists / pharmacokinetics; Hydroxyzine / administration & dosage; Hydroxyzine / blood; Hydroxyzine / pharmacokinetics; Immunoglobulin E; Injections, Intravenous
TL;DR: Pharmacokinetic and pharmacodynamic studies evaluated the suppressive effect on histamine and anticanine IgE-mediated cutaneous wheal formation and predicted that maximal antihistamine effect would occur with twice daily oral administration of hydroxyzine at 2 mg kg(-1). (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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