Paul B. Warren

Works (6)

Updated: July 5th, 2023 15:36

2020 journal article

High-Throughput Manufacture of 3D Fiber Scaffolds for Regenerative Medicine

TISSUE ENGINEERING PART C-METHODS, 26(7), 364–374.

By: R. Shirwaiker n , M. Fisher n, B. Anderson n, K. Schuchard n, P. Warren n, B. Maze n, P. Grondin n, F. Ligler n, B. Pourdeyhimi n 

author keywords: 3D printing; melt blowing; fibers; scaffolds
MeSH headings : Animals; Biocompatible Materials / chemistry; Dogs; Hernia / therapy; Herniorrhaphy / methods; Polymers / chemistry; Printing, Three-Dimensional / instrumentation; Regenerative Medicine; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR: The 3DMB system described in this study is modified from larger nonwovens manufacturing machinery to accommodate the lower volume, high-cost polymers used for tissue engineering and implantable biomedical devices and has a fiber collection component that uses adaptable robotics to create scaffolds with predetermined geometries. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 10, 2020

2019 journal article

Mechanical properties of tissue formed in vivo are affected by 3D-bioplotted scaffold microarchitecture and correlate with ECM collagen fiber alignment

Connective Tissue Research, 61(2), 190–204.

By: P. Huebner  n, P. Warren n, D. Chester n, J. Spang *, A. Brown n , M. Fisher n, R. Shirwaiker n 

author keywords: 3D printing; atomic force microscopy; elastic modulus; tissue engineering; tissue scaffolds
MeSH headings : Animals; Bioprinting; Collagen / chemistry; Extracellular Matrix / chemistry; Male; Polyesters / chemistry; Printing, Three-Dimensional; Rats; Rats, Sprague-Dawley; Tissue Engineering; Tissue Scaffolds / chemistry
TL;DR: The findings demonstrate the significant effects of 3D-bioplotted scaffold microarchitectures in the organization and sub-tissue-level mechanical properties of ECM in vivo. (via Semantic Scholar)
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5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 26, 2019

2019 journal article

Parametric control of fiber morphology and tensile mechanics in scaffolds with high aspect ratio geometry produced via melt electrowriting for musculoskeletal soft tissue engineering

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 99, 153–160.

By: P. Warren n, Z. Davis n  & M. Fisher n

author keywords: Musculoskeletal soft tissue; Additive manufacturing; Scaffold geometry; Tissue engineering
MeSH headings : Anisotropy; Biomimetics; Collagen / chemistry; Electrochemistry; Extracellular Matrix / metabolism; Materials Testing; Temperature; Tensile Strength; Tissue Engineering / instrumentation; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR: The need to tailor MEW process parameters in scaffolds with high aspect ratio geometry in order to consistently generate specific structural and mechanical properties is highlighted. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: September 30, 2019

2017 journal article

Macrophages' role in tissue disease and regeneration

Macrophages: Origin, Functions and Biointervention, 62, 245–271.

By: L. Gaffney, P. Warren, E. Wrona, M. Fisher & D. Freytes

Source: NC State University Libraries
Added: August 6, 2018

2017 review

Rise of the Pigs: Utilization of the Porcine Model to Study Musculoskeletal Biomechanics and Tissue Engineering During Skeletal Growth

[Review of ]. TISSUE ENGINEERING PART C-METHODS, 23(11), 763–780.

By: S. Cone  n, P. Warren n & M. Fisher n

author keywords: animal models; ligament and tendon; cartilage; bone; skeletal muscle
MeSH headings : Animals; Biomechanical Phenomena; Bone Development; Models, Animal; Musculoskeletal Physiological Phenomena; Regenerative Medicine; Sus scrofa; Tissue Engineering
TL;DR: This review explores the publication history of the use of pig models in biomechanics and TERM discuss interspecies comparative studies, highlight studies on the effect of skeletal growth and other biological considerations in the porcine model, and present challenges and emerging opportunities for using this model to study functional TERM. (via Semantic Scholar)
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5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Engineering 3D-Bioplotted scaffolds to induce aligned extracellular matrix deposition for musculoskeletal soft tissue replacement

CONNECTIVE TISSUE RESEARCH, 58(3-4), 342–354.

By: P. Warren n, P. Huebner  n, J. Spang *, R. Shirwaiker n  & M. Fisher n

Contributors: P. Warren n, P. Huebner  n, J. Spang *, R. Shirwaiker n  & M. Fisher n

author keywords: Biofabrication; meniscus; tissue engineering; scaffold; 3D printing
MeSH headings : Animals; Cell Count; Cell Shape; Collagen / metabolism; Extracellular Matrix / metabolism; Imaging, Three-Dimensional; Male; Musculoskeletal Physiological Phenomena; Rats, Sprague-Dawley; Regeneration / physiology; Sus scrofa; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR: The ability to use interstrand spacing as a means of controlling the formation of aligned collagen in vivo was demonstrated, which helps establish a design space for scaffold-based meniscus tissue engineering. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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