Patricia D. McClellan-Green

Works (16)

Updated: July 7th, 2023 21:15

2023 article

Using Plasma Vitellogenin in Loggerhead Sea Turtles to Assess Reproductive Maturation and Estrogen-Like Contaminant Exposure

Corniuk, R. N., Lynch, J. M., Arendt, M. D., Braun-McNeill, J., Owens, D. W., Valverde, R. A., … McClellan-Green, P. D. (2023, May 8). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY.

By: R. Corniuk*, J. Lynch *, M. Arendt *, J. Braun-McNeill*, D. Owens *, R. Valverde *, J. Kucklick *, P. McClellan-Green n

author keywords: Endocrine disruptors; Endocrine-disrupting compounds; Persistent organic pollutants; Organic contaminants
MeSH headings : Animals; Female; Male; Vitellogenins / metabolism; Turtles / metabolism; Polychlorinated Biphenyls / metabolism; Antibodies / metabolism; Estrogens / metabolism
TL;DR: Plasma VTG expression cannot conclusively be linked to endocrine disruption caused by these OC concentrations, which motivated the creation of a conceptual model of OC, VTG, and hormone concentrations across a reproductive cycle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: May 22, 2023

2019 journal article

Crude Oil and Dispersant Cause Acute Clinicopathological Abnormalities in Hatchling Loggerhead Sea Turtles (Caretta caretta)

FRONTIERS IN VETERINARY SCIENCE, 6.

By: C. Harms n , P. McClellan-Green n, M. Godfrey n, E. Christiansen n, H. Broadhurst n & C. Godard-Codding *

author keywords: Caretta caretta; corexit; crude oil; dispersant; hematology; loggerhead sea turtle; plasma biochemistry
TL;DR: Clinopathological findings were supported by a failure to gain weight (associated with normal hatchling hydration in seawater) in dispersant and combination exposed hatchlings, and indicate potential impacts on wildlife to consider when deploying dispersants in an oil spill response. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: December 9, 2019

2019 journal article

NMR Metabolomic Analysis of Skeletal Muscle, Heart, and Liver of Hatchling Loggerhead Sea Turtles (Caretta caretta) Experimentally Exposed to Crude Oil and/or Corexit

Metabolites, 9(2), 21.

By: S. Bembenek-Bailey  n, J. Niemuth n , P. McClellan-Green n, M. Godfrey n, C. Harms n , H. Gracz n, M. Stoskopf n

author keywords: Caretta caretta; Corexit 9500A; crude oil; heart; liver; metabolomics; NMR; sea turtle; skeletal muscle
TL;DR: Observed decreases in concentrations of lactate and creatines may reflect energy depletion in skeletal muscle of oil-exposed animals, while decreased taurine concentrations in these animals may reflect higher oxidative stress. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: February 11, 2019

2015 journal article

Control of Histamine-Producing Bacteria and Histamine Formation in Fish Muscle by Trisodium Phosphate

JOURNAL OF FOOD SCIENCE, 80(6), M1253–M1258.

By: K. Bjornsdottir-Butler  n, D. Green n, G. Bolton n & P. McClellan-Green n

author keywords: bacteria; barrier; fish; histamine; histidine decarboxylase; pH
MeSH headings : Animals; Bacteria / drug effects; Bacteria / growth & development; Bacteria / metabolism; Food Contamination / analysis; Food Handling / methods; Foodborne Diseases / microbiology; Histamine / metabolism; Marine Toxins / metabolism; Marine Toxins / poisoning; Muscles / metabolism; Perciformes / microbiology; Phosphates / pharmacology; Seafood / analysis; Seafood / microbiology; Tuna / microbiology
TL;DR: It is revealed that phosphate treatment of mahi-mahi and tuna fish muscle resulted in significantly lower histamine production over 4 d of storage at 10 °C, which may serve as a secondary barrier in addition to FDA recommended time and temperature controls for reducing public health concerns of scombrotoxin fish poisoning. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Dietary CdSe/ZnS quantum dot exposure in estuarine fish: Bioavailability, oxidative stress responses, reproduction, and maternal transfer

Aquatic Toxicology (Amsterdam, Netherlands), 148, 27–39.

By: T. Blickley, C. Matson, W. Vreeland, D. Rittschof, R. Di Giulio & P. McClellan-Green

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Variation in toxicity of copper pyrithione among populations and families of the barnacle, Balanus amphitrite

Biofouling, 26(3), 341–347.

By: J. Romano, D. Rittschof, P. McClellan-Green & E. Holm

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Toxicity of aqueous fullerene in adult and larval Fundulus heteroclitus

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 27(9), 1964–1971.

By: T. Blickley* & P. McClellan-Green n

author keywords: fullerene; glutathione; chorion; nanoparticle; toxicity
MeSH headings : Animals; Chorion / drug effects; Chorion / metabolism; Chorion / pathology; Embryo, Nonmammalian / drug effects; Female; Fullerenes / chemistry; Fullerenes / toxicity; Fundulidae / growth & development; Fundulidae / physiology; Gills / drug effects; Gills / metabolism; Gills / pathology; Glutathione / metabolism; Larva; Lipid Peroxidation / drug effects; Liver / drug effects; Liver / metabolism; Liver / pathology; Malondialdehyde / metabolism; Nanoparticles / chemistry; Nanoparticles / toxicity; Oxidative Stress / drug effects; Solubility; Suspensions
TL;DR: It is concluded that aqua‐nC60 affects the oxidative stress response of F. heteroclitus and that increased antioxidant defenses provide some physiological tolerance for these materials. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Ecotoxicology of carbon-based engineered nanoparticles: Effects of fullerene (C-60) on aquatic organisms

CARBON, 44(6), 1112–1120.

By: E. Oberdorster*, S. Zhu*, T. Blickley*, P. McClellan-Green n & M. Haasch*

author keywords: fullerene; carbon nanotubes; bioactivity
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Effects of organochlorine contaminants on loggerhead sea turtle immunity: Comparison of a correlative field study and in vitro exposure experiments

ENVIRONMENTAL HEALTH PERSPECTIVES, 114(1), 70–76.

By: J. Keller*, P. McClellan-Green n, . Kucklick *, D. Keil & M. Peden-Adams*

author keywords: DDT; immunotoxicity; organochlorine contaminants; organochlorine pesticides; PCBs; persistent organic pollutants; polychlorinated biphenyls; reptile
MeSH headings : Animals; Cell Proliferation / drug effects; Cells, Cultured; Chickens; Environmental Monitoring; Hydrocarbons, Chlorinated / blood; Hydrocarbons, Chlorinated / toxicity; Lymphocytes / cytology; Lymphocytes / drug effects; Lymphocytes / immunology; Mitogens / pharmacology; Muramidase / immunology; Turtles / immunology; Water Pollutants, Chemical / blood; Water Pollutants, Chemical / toxicity
TL;DR: Current, chronic exposure to OCs may suppress innate immunity and enhance certain lymphocyte functions of loggerhead sea turtles, and correlative observations in free-ranging turtles suggest that OC exposure modulates immunity in loggerhead turtles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Molluscs as multidisciplinary models in environment toxicology

MARINE POLLUTION BULLETIN, 50(4), 369–373.

By: D. Rittschof* & P. McClellan-Green n

author keywords: multidisciplinary toxicology models; molluscs; imposex; environmental toxicology; endocrine disruptors; molecular biology; behavior
MeSH headings : Animals; Environment; Models, Animal; Mollusca; Toxicology / methods
TL;DR: This paper has attempted to provide initial references as an avenue into the literature and as a means for researchers to expand their thoughts to regions outside of their own area of expertise. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 article

The neuropeptide APGWamide as a penis morphogenic factor (PMF) in gastropod mollusks

Oberdorster, E., Romano, J., & McClellan-Green, P. (2005, February). INTEGRATIVE AND COMPARATIVE BIOLOGY, Vol. 45, pp. 28–32.

By: E. Oberdorster*, J. Romano & P. McClellan-Green

TL;DR: The pattern of APGWamide in imposex snails was similar to male snails, showing large patches of immuno-reactive areas in the top portion of the visceral mass, and in femaleSnails, no areas of cross-reactivity were found. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Associations between organochlorine contaminant concentrations and clinical health parameters in loggerhead sea turtles from North Carolina, USA

ENVIRONMENTAL HEALTH PERSPECTIVES, 112(10), 1074–1079.

By: J. Keller*, . Kucklick *, M. Stamper*, C. Harms n  & P. McClellan-Green n

MeSH headings : Anemia / etiology; Anemia / veterinary; Animals; Animals, Wild; Biopsy; Environmental Pollutants / pharmacokinetics; Environmental Pollutants / poisoning; Erythrocyte Count; Female; Hematocrit; Insecticides / pharmacokinetics; Insecticides / poisoning; Liver / pathology; Male; North Carolina; Polychlorinated Biphenyls / pharmacokinetics; Polychlorinated Biphenyls / poisoning; Proteins / metabolism; Tissue Distribution; Turtles / physiology; Water Pollutants, Chemical / pharmacokinetics; Water Pollutants, Chemical / poisoning; Water-Electrolyte Balance
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 article

Effects of organochlorine compounds on cytochrome P450 aromatase activity in an immortal sea turtle cell line

MARINE ENVIRONMENTAL RESEARCH, Vol. 58, pp. 347–351.

By: J. Keller* & P. McClellan-Green n

author keywords: sea turtle; endocrine; aromatase; cell line; testis; atrazine; DDE
MeSH headings : 8-Bromo Cyclic Adenosine Monophosphate / pharmacology; Androstenedione / analogs & derivatives; Androstenedione / pharmacology; Animals; Aromatase / biosynthesis; Aromatase Inhibitors; Atrazine / pharmacology; Cell Line; Chorionic Gonadotropin / pharmacology; Dexamethasone / pharmacology; Dichlorodiphenyl Dichloroethylene / pharmacology; Enzyme Induction / drug effects; Time Factors; Tritium; Turtles / metabolism
TL;DR: This in vitro model can be useful in examining the endocrine effects of EACs in sea turtles by examining their ability to alter cytochrome P450 aromatase (CYP19) activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Organochlorine contaminants in loggerhead sea turtle blood: Extraction techniques and distribution among plasma and red blood cells

Archives of Environmental Contamination and Toxicology (Online), 46(2), 254–264.

By: J. Keller, J. Kucklick & P. McClellan-Green

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Organochlorine contaminants in sea turtles: Correlations between whole blood and fat

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 23(3), 726–738.

By: J. Keller*, . Kucklick *, C. Harms n  & P. McClellan-Green n

author keywords: loggerhead; Kemp's ridley; organochlorine; blood; fat
MeSH headings : Adipose Tissue / chemistry; Animals; Atlantic Ocean; Chromatography, Gas; Environmental Monitoring / methods; Environmental Monitoring / statistics & numerical data; Insecticides / analysis; Insecticides / blood; Mass Spectrometry; North Carolina; Polychlorinated Biphenyls / analysis; Polychlorinated Biphenyls / blood; Turtles / metabolism
TL;DR: Blood OC concentrations calculated on a wet-mass basis were significantly and inversely correlated to lipid content in the fat samples of sea turtles, suggesting that sea turtle blood is a suitable alternative to fatty tissues for measuring OCs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Mechanisms of imposex induction in the mud snail, Ilyanassa obsoleta: TBT as a neurotoxin and aromatase inhibitor

Marine Environmental Research, 54(3-5), 715–718.

By: E. Oberdorster* & P. McClellan-Green n

MeSH headings : Animals; Aromatase Inhibitors; Disorders of Sex Development / etiology; Disorders of Sex Development / veterinary; Dose-Response Relationship, Drug; Female; Gonadal Steroid Hormones / pharmacology; Neuropeptides / pharmacology; Snails / anatomy & histology; Snails / physiology; Trialkyltin Compounds / adverse effects; Water Pollutants, Chemical / adverse effects
TL;DR: The occurrence of imposex, imposition of male sex characteristics on female snails, has been extensively documented throughout the world and it is possible that the combination of changes in peptide and steroid hormones may lead to imposex induction at extremely low doses of TBT. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

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