@misc{need_attix_mcevoy_cirulli_linney_hunt_ge_heinzen_maia_shianna_et al._2009, title={A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB}, volume={18}, number={23}, journal={Human Molecular Genetics}, author={Need, A. C. and Attix, D. K. and McEvoy, J. M. and Cirulli, E. T. and Linney, K. L. and Hunt, P. and Ge, D. L. and Heinzen, E. L. and Maia, J. M. and Shianna, K. V. and et al.}, year={2009}, pages={4650–4661} } @article{goering_hunt_heighington_busick_pennings_hermisson_kumar_gibson_2009, title={Association of orthodenticle with Natural Variation for Early Embryonic Patterning in Drosophila melanogaster}, volume={312B}, ISSN={["1552-5015"]}, DOI={10.1002/jez.b.21299}, abstractNote={Abstract}, number={8}, journal={JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION}, author={Goering, Lisa M. and Hunt, Priscilla K. and Heighington, Cassandra and Busick, Christopher and Pennings, Pleuni S. and Hermisson, Joachim and Kumar, Sudhir and Gibson, Greg}, year={2009}, month={Dec}, pages={841–854} } @article{passador-gurgel_hsieh_hunt_deighton_gibson_2007, title={Quantitative trait transcripts for nicotine resistance in Drosophila melanogaster}, volume={39}, ISSN={["1061-4036"]}, DOI={10.1038/ng1944}, abstractNote={Although most genetic association studies are performed with the intention of detecting nucleotide polymorphisms that are correlated with a complex trait, transcript abundance should also be expected to associate with diseases or phenotypes. We performed a scan for such quantitative trait transcripts in adult female heads of the fruit fly (Drosophila melanogaster) that might explain variation for nicotine resistance. The strongest association was seen for abundance of ornithine aminotransferase transcripts, implicating detoxification and neurotransmitter biosynthesis as mediators of the quantitative response to the drug. Subsequently, genetic analysis and metabolite profiling confirmed a complex role for ornithine and GABA levels in modification of survival time upon chronic nicotine exposure. Differences between populations from North Carolina and California suggest that the resistance mechanism may be an evolved response to environmental exposure.}, number={2}, journal={NATURE GENETICS}, author={Passador-Gurgel, Gisele and Hsieh, Wen-Ping and Hunt, Priscilla and Deighton, Nigel and Gibson, Greg}, year={2007}, month={Feb}, pages={264–268} }