Works (12)
Updated: July 5th, 2023 15:58
2018 journal article
Articular cartilage gene expression patterns in the tissue surrounding the impact site following applications of shear and axial loads
BMC Musculoskeletal Disorders, 19(1).
author keywords: Osteoarthritis; Porcine; Articular injury
MeSH headings : Animals; Cartilage, Articular / metabolism; Cartilage, Articular / pathology; Collagen Type II / genetics; Collagen Type II / metabolism; Gene Expression Profiling / methods; Gene Expression Regulation, Enzymologic; Osteoarthritis, Knee / genetics; Osteoarthritis, Knee / metabolism; Osteoarthritis, Knee / pathology; Patella / metabolism; Patella / pathology; Stress, Mechanical; Sus scrofa; Time Factors; Tissue Culture Techniques; Transcriptome; fas Receptor / genetics; fas Receptor / metabolism
TL;DR:
The results suggest that a more physiologically valid shear load may induce more damage to surrounding articular cartilage than a normal load alone.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: January 14, 2019
2015 journal article
In vitro biomechanical evaluation of internal fixation techniques on the canine lumbosacral junction
PeerJ, 3.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Study on the damage mechanism of articular cartilage based on the fluid-solid coupled particle model
Advances in Mechanical Engineering, 7(4).
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
Changes in chondrocyte gene expression following in vitro impaction of porcine articular cartilage in an impact injury model
JOURNAL OF ORTHOPAEDIC RESEARCH, 31(3), 385–391.
Contributors: M. Ashwell n, M. Gonda n, K. Gray n, C. Maltecca n , . A.T. O'Nan n, J. Cassady n, n
author keywords: articular cartilage; chondrocyte; gene expression; joint injury; osteoarthritis
MeSH headings : Animals; Cartilage, Articular / cytology; Cartilage, Articular / physiology; Chondrocytes / physiology; Female; Knee Injuries / genetics; Knee Injuries / physiopathology; Knee Joint / cytology; Knee Joint / physiology; Models, Genetic; Organ Culture Techniques; Osteoarthritis, Knee / genetics; Osteoarthritis, Knee / physiopathology; Patella / cytology; Patella / physiology; Real-Time Polymerase Chain Reaction; Sus scrofa; Transcriptome / physiology
TL;DR:
Ten of the 17 genes were differentially expressed with col1a1 most significantly up‐regulated in the impacted samples, suggesting impacted chondrocytes may have reverted to a fibroblast‐like phenotype.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2009 journal article
Biomechanical Comparison of Four Soft Tissue Replacement Materials: An In Vitro Evaluation of Single and Multilaminate Porcine Small Intestinal Submucosa, Canine Fascia Lata, and Polypropylene Mesh
VETERINARY SURGERY, 38(7), 834–844.
MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dogs; Fascia Lata; Intestinal Mucosa / physiology; Intestine, Small / physiology; Materials Testing / veterinary; Mollusk Venoms; Polypropylenes; Surgical Mesh / veterinary; Swine; Tensile Strength
TL;DR:
Compared with previous studies, PM accommodated a significantly higher load and energy to yield when its longitudinal cords were oriented parallel with the tension axis, and MLSIS had biomechanical characteristics that were inferior to FL and PM but superior to SIS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 journal article
Gene expression profiling of chondrocytes from a porcine impact injury model
OSTEOARTHRITIS AND CARTILAGE, 16(8), 936–946.
author keywords: gene expression; chondrocyte; impact injury model; osteoarthritis
MeSH headings : Animals; Cells, Cultured / metabolism; Chondrocytes / metabolism; Disease Models, Animal; Gene Expression; Gene Expression Profiling / methods; Knee Joint / metabolism; Osteoarthritis / genetics; Osteoarthritis / metabolism; Phenotype; Polymerase Chain Reaction; Swine; Wounds, Nonpenetrating / genetics; Wounds, Nonpenetrating / metabolism
TL;DR:
Results using this porcine impact injury model have contributed further evidence that damaged chondrocytes may de-differentiate into fibroblast-like cells and proliferate in an attempt to repair themselves and provide a more complete story about the fate of chondROcytes in articular cartilage following an injury.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 journal article
Organic trace minerals and 25-hydroxycholecalciferol affect performance characteristics, leg abnormalities, and biomechanical properties of leg bones of turkeys
POULTRY SCIENCE, 88(1), 118–131.
author keywords: turkey; organic trace mineral; 25-hydroxycholecalciferol; leg problem; bone
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Biomechanical Phenomena; Bone Development / drug effects; Bone and Bones / drug effects; Calcifediol / pharmacology; Diet; Dietary Supplements; Hindlimb / pathology; Lameness, Animal / drug therapy; Male; Trace Elements / pharmacology; Turkeys / growth & development; Walking / physiology
TL;DR:
Dietary MIN supplementation may improve feed conversion of turkeys, likely by decreasing leg problems and maximum shear stress at failure of femoral bones in a torsion assay was increased by supplementation with both MIN and HyD together.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Two photon polymerization of polymer-ceramic hybrid materials for transdermal drug delivery
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY, 4(1), 22–29.
Contributors: A. Ovsianikov *, B. Chichkov *, n, N. Monteiro-Riviere n , A. Doraiswamy * & R. Narayan n
TL;DR:
2PP is able to create microneedle structures for transdermal drug delivery with a larger range of geometries than conventional microfabrication techniques, and human epidermal keratinocyte viability on the Ormocer® surfaces polymerized using 2PP was similar to that on control surfaces.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 article
Median sternotomy closure in dogs: A mechanical comparison of technique stability
Davis, K. M., Roe, S. C., Mathews, K. G., & Mente, P. L. (2006, April). VETERINARY SURGERY, Vol. 35, pp. 271–277.
MeSH headings : Animals; Bone Wires / veterinary; Dogs / surgery; Radiography; Sternum / diagnostic imaging; Sternum / surgery; Suture Techniques / veterinary; Thoracic Surgical Procedures / methods; Thoracic Surgical Procedures / veterinary
TL;DR:
Sternal wiring techniques stabilizing sternal synchondroses had the least displacement and figure of 8 cerclage appeared most suitable because they minimized displacement at high loads and facilitated accurate reduction during tensioning.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Two photon induced polymerization of organic-inorganic hybrid biomaterials for microstructured medical devices
ACTA BIOMATERIALIA, 2(3), 267–275.
author keywords: two photon induced polymerization; Ormocer (R); tissue engineering; microneedles
MeSH headings : Animals; Drug Carriers; Equipment Design / methods; Equipment and Supplies; Inorganic Chemicals / chemistry; Materials Testing / methods; Microchemistry / methods; Microscopy, Electron, Scanning; Neurons / cytology; Neurons / ultrastructure; Organic Chemicals / chemistry; Photons; X-Ray Diffraction
TL;DR:
Three-dimensional microstructured medical devices, including microneedles and tissue engineering scaffolds, were fabricated by two photon induced polymerization of Ormocer organic-inorganic hybrid materials to suggest that two photon inducing polymerization is able to create medical microdevices with a larger range of sizes, shapes, and materials than conventional microfabrication techniques.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Biomechanical evaluation of suture pullout from canine arytenoid cartilages: Effects of hole diameter, suture configuration, suture size, and distraction rate
VETERINARY SURGERY, 33(3), 191–199.
MeSH headings : Animals; Arytenoid Cartilage / surgery; Biomechanical Phenomena; Dogs / surgery; Equipment Failure; Needles / veterinary; Suture Techniques / instrumentation; Suture Techniques / veterinary; Sutures / veterinary
TL;DR:
Suture and hole sizes appear to have few effects on the biomechanical performance of arytenoid-suture constructs, and double suture and horizontal mattress suture patterns had the best overall mechanical properties for aryTenoid lateralization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 conference paper
Outcomes based curriculum development in a new and emerging biomedical engineering program
American Society for Engineering Education.
Source: NC State University Libraries
Added: August 6, 2018
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