Paul Schlosser

Works (12)

Updated: July 5th, 2023 16:04
Download BibTeX Download Plain Text View JSON

2010 journal article

A Multicompartment Liver-based Pharmacokinetic Model for Benzene and its Metabolites in Mice

BULLETIN OF MATHEMATICAL BIOLOGY, 72(3), 507–540.

By: C. Manning n, P. Schlosser* & H. Tran n 

co-author countries: United States of America 🇺🇸
author keywords: Benzene metabolism model; Ordinary differential equations; Existence and uniqueness; Inverse problems
MeSH headings : Animals; Benzene / pharmacokinetics; Cytochrome P-450 CYP2E1 / metabolism; Glutathione / metabolism; Liver / enzymology; Liver / metabolism; Mice; Models, Biological
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Sensory irritation response in rats: Modeling, analysis and validation

BULLETIN OF MATHEMATICAL BIOLOGY, 70(2), 555–588.

By: K. Yokley n, H. Tran n  & P. Schlosser*

co-author countries: United States of America 🇺🇸
author keywords: sensory response; PBPK; formaldehyde
MeSH headings : Animals; Computer Simulation; Dose-Response Relationship, Drug; Feedback, Physiological; Formaldehyde / toxicity; Gases / toxicity; Hypoventilation / etiology; Hypoventilation / physiopathology; Hypoventilation / veterinary; Inhalation Exposure; Irritants / toxicity; Models, Biological; Neuroepithelial Cells / drug effects; Neuroepithelial Cells / physiology; Pulmonary Ventilation / drug effects; Rats; Respiration / drug effects; Respiratory System / drug effects; Respiratory System / innervation; Respiratory System / physiopathology; Sensation / drug effects; Sensation / physiology; Trigeminal Nerve / drug effects; Trigeminal Nerve / physiopathology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

A delayed nonlinear PBPK model for genistein dosimetry in rats

BULLETIN OF MATHEMATICAL BIOLOGY, 69(1), 93–117.

By: M. Zagera, P. Schlosser* & H. Tran n 

co-author countries: United States of America 🇺🇸
author keywords: genistein; biliary excretion; pharmacokinetics; delay-differential equations
MeSH headings : Animals; Bile / metabolism; Biliary Tract / drug effects; Biliary Tract / metabolism; Genistein / pharmacokinetics; Genistein / pharmacology; Models, Biological; Nonlinear Dynamics; Rats
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Physiologically-based pharmacokinetic modeling of genistein in rats, part I: Model development

RISK ANALYSIS, 26(2), 483–500.

By: P. Schlosser*, S. Borghoff, N. Coldham, J. David & S. Ghosh* 

Contributors: P. Schlosser*, S. Borghoff, N. Coldham, J. David & S. Ghosh* 

author keywords: endocrine-active; genistein; PBPK; phytoestrogen; rat
MeSH headings : Animals; Blood Proteins / metabolism; Female; Genistein / administration & dosage; Genistein / blood; Genistein / pharmacokinetics; Humans; Male; Models, Biological; Phytoestrogens / administration & dosage; Phytoestrogens / blood; Phytoestrogens / pharmacokinetics; Protein Binding; Rats; Rats, Sprague-Dawley; Rats, Wistar; Risk; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

Multiple stable periodic solutions in a model for hormonal control of the menstrual cycle

BULLETIN OF MATHEMATICAL BIOLOGY, 65(1), 157–173.

By: L. Clark, P. Schlosser & J. Selgrade

Source: Web Of Science
Added: August 6, 2018

2001 review

A review of quantitative studies of benzene metabolism

[Review of ]. CRITICAL REVIEWS IN TOXICOLOGY, 31(3), 285–311.

By: M. Lovern*, C. Cole n & P. Schlosser*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Benzene / administration & dosage; Benzene / metabolism; Benzene / pharmacokinetics; Enzyme Induction / drug effects; Female; Humans; In Vitro Techniques; Male; Microsomes / metabolism; Models, Theoretical
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Physiologically based pharmacokinetic modeling of benzene metabolism in mice through extrapolation from in vitro to in vivo

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A, 62(6), 439–465.

By: C. Cole n, H. Tran n  & P. Schlosser n

co-author countries: United States of America 🇺🇸
MeSH headings : Administration, Inhalation; Algorithms; Animals; Benzene / chemistry; Benzene / metabolism; Benzene / pharmacokinetics; Benzene Derivatives / chemistry; Benzene Derivatives / metabolism; Benzene Derivatives / pharmacokinetics; Chemical Phenomena; Chemistry, Physical; Mice; Models, Biological; Risk Assessment
Sources: Web Of Science, ORCID
Added: August 6, 2018

2000 journal article

A model of gonadotropin regulation during the menstrual cycle in women: Qualitative features

ENVIRONMENTAL HEALTH PERSPECTIVES, 108, 873–881.

By: P. Schlosser* & J. Selgrade*

author keywords: estradiol; follicle-stimulating hormone; luteinizing hormone; mathematical model; menstrual cycle; progesterone
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Renewal and circulation of intermediate waters in the Canadian Basin observed on the SCICEX 96 cruise

JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS, 105(C1), 1105–1121.

By: W. Smethie, P. Schlosser*, G. Bonisch & T. Hopkins*

Source: Web Of Science
Added: August 6, 2018

1999 journal article

Use of a mathematical model of rodent in vitro benzene metabolism to predict human in vitro metabolism data

CARCINOGENESIS, 20(8), 1511–1520.

By: M. Lovern n, M. Maris n & P. Schlosser*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Benzene / metabolism; Carcinogens / metabolism; Cytochrome P-450 CYP2E1 / metabolism; Cytochrome P-450 CYP2E1 Inhibitors; Enzyme Inhibitors / pharmacology; Humans; Male; Mice; Microsomes, Liver / drug effects; Microsomes, Liver / metabolism; Models, Biological; Quaternary Ammonium Compounds / pharmacology; Rats; Rats, Inbred F344; Trichloroepoxypropane / pharmacology
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Application of a photographic method for determining mass transfer to flow around a submerged parallelepiped

INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 41(19), 2991–3004.

By: P. Schlosser*, M. Godo*, T. Fornes n & E. Hubal n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Identification of benzene oxide as a product of benzene metabolism by mouse, rat, and human liver microsomes

CARCINOGENESIS, 18(9), 1695–1700.

By: M. Lovern n, M. Turner, M. Meyer, G. Kedderis, W. Bechtold & P. Schlosser*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Benzene / metabolism; Chromatography, High Pressure Liquid; Cyclohexanes / metabolism; Gas Chromatography-Mass Spectrometry; Humans; Male; Mice; Microsomes, Liver / metabolism; Rats; Rats, Inbred F344; Species Specificity
Source: Web Of Science
Added: August 6, 2018