Works (26)

Updated: April 4th, 2024 02:54

2024 journal article

Characterization of an Injectable Chitosan Hydrogel for the Tunable, Localized Delivery of Immunotherapeutics

ACS BIOMATERIALS SCIENCE & ENGINEERING, 10(2), 905–920.

By: S. Mantooth n, A. Hancock n, P. Thompson n, P. Varghese n, D. Meritet n, M. Vrabel n, J. Hu n, D. Zaharoff n

author keywords: hydrogel; chitosan; immunotherapy; intratumoral
Sources: Web Of Science, ORCID
Added: March 4, 2024

2024 journal article

Fructose regulates the pentose phosphate pathway and induces an inflammatory and resolution phenotype in Kupffer cells

SCIENTIFIC REPORTS, 14(1).

By: M. Lodge, G. Scheidemantle, V. Adams*, M. Cottam, D. Richard, D. Breuer, P. Thompson*, K. Shrestha*, X. Liu*, A. Kennedy*

Sources: Web Of Science, ORCID
Added: March 25, 2024

2023 journal article

Excision of a Protein-Derived Amine for p-Aminobenzoate Assembly by the Self-Sacrificial Heterobimetallic Protein CADD

BIOCHEMISTRY, 62(22), 3276–3282.

By: H. Phan n, O. Manley n, S. Skirboll n, L. Cha n, D. Hilovsky n, W. Chang n, P. Thompson n, X. Liu n, T. Makris n

Sources: Web Of Science, ORCID
Added: December 12, 2023

2022 journal article

An adaptive teosinte mexicana introgression modulates phosphatidylcholine levels and is associated with maize flowering time

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(27).

By: A. Barnes n, F. Rodriguez-Zapata n, K. Juarez-Nunez, D. Gates*, G. Janzen*, A. Kur n, L. Wang*, S. Jensen* ...

co-author countries: Mexico 🇲🇽

Contributors: P. Thompson n

author keywords: phospholipid metabolism; maize genetics; highland adaptation; flowering time; selection
Sources: ORCID, Web Of Science
Added: August 3, 2022

2021 journal article

The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism.

Proceedings of the National Academy of Sciences of the United States of America, 118(11).

By: A. Foo*, P. Thompson*, S. Chen*, R. Jadi*, B. Lupo*, E. DeRose*, S. Arora*, V. Placentra* ...

author keywords: antiviral; membrane disruption; cytolysis; insect digestion; insect immune response
MeSH headings : Animals; Antiviral Agents / chemistry; Antiviral Agents / metabolism; Antiviral Agents / pharmacology; Cell Line; Cell Membrane / metabolism; Culicidae; Erythrocytes / drug effects; Fatty Acids, Unsaturated / metabolism; Hemolytic Agents / chemistry; Hemolytic Agents / metabolism; Hemolytic Agents / pharmacology; Humans; Hydrophobic and Hydrophilic Interactions; Insect Proteins / chemistry; Insect Proteins / metabolism; Insect Proteins / pharmacology; Ligands; Lipids / chemistry; Protein Binding; Protein Structure, Tertiary; Viral Envelope / metabolism; Viruses / drug effects; Viruses / metabolism
Source: ORCID
Added: March 14, 2021

2020 journal article

Mixture analyses of air-sampled pollen extracts can accurately differentiate pollen taxa

ATMOSPHERIC ENVIRONMENT, 243.

By: L. Klimczak*, C. Eschenbach*, P. Thompson n, J. Buters* & G. Mueller*

co-author countries: Germany 🇩🇪
author keywords: Pollen; NMR; Metabolomics; Mixtures; Exposure; Aerobiology
Sources: Web Of Science, ORCID
Added: November 24, 2020

2019 journal article

Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1

Scientific Reports, 9(1).

MeSH headings : Allergens / chemistry; Allergens / immunology; Animals; Antigen Presentation; Blattellidae / immunology; Fatty Acids / immunology; Fatty Acids / metabolism; Insect Proteins / chemistry; Insect Proteins / immunology; Ligands; Phospholipids / immunology; Phospholipids / metabolism; Protein Binding / immunology; Protein Stability; Protein Structure, Tertiary
Source: ORCID
Added: December 10, 2019

2019 conference paper

Influence of Hydrophobic Cargo Binding on the Structure, Stability, and Allergenicity of the Cockroach Allergen Bla g 1

Journal of Allergy and Clinical Immunology.

Peter Thompson

Source: ORCID
Added: December 10, 2019

2019 journal article

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity.

Allergy.

Peter Thompson

author keywords: allergenicity; birch pollen extract; E-1 phytoprostanes; ligand interaction; lysosomal protease inhibition
MeSH headings : Allergens / immunology; Antigens, Plant / immunology; Basophils / immunology; Basophils / metabolism; Betula / immunology; Cell Degranulation / immunology; Endosomes / enzymology; Enzyme Activation; Humans; Immunoglobulin E / immunology; Ligands; Peptide Hydrolases / metabolism; Pollen / immunology; Protein Binding; Recombinant Proteins
Source: ORCID
Added: May 12, 2021

2017 journal article

A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization.

Structure (London, England : 1993).

Peter Thompson

MeSH headings : Actin Cytoskeleton / genetics; Actin Cytoskeleton / metabolism; Actins / genetics; Actins / metabolism; Amino Acid Motifs; Animals; Binding Sites; Embryo, Mammalian; Fibroblasts / metabolism; Fibroblasts / ultrastructure; Focal Adhesions / metabolism; Focal Adhesions / ultrastructure; Gene Expression; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers / chemistry; Lipid Bilayers / metabolism; Mechanotransduction, Cellular; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylinositol 4,5-Diphosphate / chemistry; Phosphatidylinositol 4,5-Diphosphate / metabolism; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Thermodynamics; Vinculin / chemistry; Vinculin / genetics; Vinculin / metabolism
Source: ORCID
Added: May 12, 2021

2017 conference paper

Role of PIP2-Dependent Membrane Interactions in Vinculin Activation, Motility and Force Transmission

Biophysical Journal.

Peter Thompson

Source: ORCID
Added: December 10, 2019

2016 journal article

A metabolomic, geographic, and seasonal analysis of the contribution of pollen-derived adenosine to allergic sensitization

Metabolomics.

Peter Thompson

author keywords: NMR; Metabolomics; Pollen; Adenosine; Allergy
Source: ORCID
Added: December 10, 2019

2016 journal article

Role of PIP2-Dependent Membrane Interactions in Vinculin Activation, Motility and Force Transmission

Biophysical Journal, 110(3), 575a.

By: S. Campbell*, P. Thompson*, C. Tolbert*, L. Case*, S. Ramachandran*, M. Pershad*, N. Dokholyan*, K. Burridge*, C. Waterman*

Source: ORCID
Added: December 10, 2019

2016 journal article

The Structural Basis of Actin Organization by Vinculin and Metavinculin

Journal of Molecular Biology, 428(1), 10–25.

By: L. Kim*, P. Thompson*, H. Lee*, M. Pershad*, S. Campbell* & G. Alushin*

author keywords: cryo-EM; cytoskeleton; mechanobiology; adhesion; cell motility
MeSH headings : Actins / chemistry; Actins / metabolism; Cryoelectron Microscopy; Humans; Models, Molecular; Protein Binding; Protein Conformation; Protein Multimerization; Vinculin / chemistry; Vinculin / metabolism
Source: ORCID
Added: December 10, 2019

2015 article

MDFF model of the vinculin tail domain bound to F-actin

Kim, L. Y., Thompson, P. M., Lee, H. T., Pershad, M., Campbell, S. L., & Alushin, G. M. (2015, November 4).

By: L. Kim, P. Thompson*, H. Lee, M. Pershad, S. Campbell & G. Alushin

Source: ORCID
Added: December 10, 2019

2015 journal article

New Models for Regulation of Vinculin by Actin and Phospholipids

Biophysical Journal, 108(2), 508a–509a.

By: P. Thompson*, H. Lee*, L. Kim*, S. Ramachandran*, A. Tandon*, R. Mendez-Giraldez*, G. Alushin*, N. Dokholyan*, S. Campbell*

Source: ORCID
Added: December 10, 2019

2015 article

Protein-Protein Interaction Analysis by Nuclear Magnetic Resonance Spectroscopy

Protein-Protein Interactions, pp. 267–279.

By: P. Thompson*, M. Beck & S. Campbell

author keywords: Pulsed-field gel electrophoresis (PFGE); Salmonella enterica; Molecular typing; PulseNet; Agarose gel; Enteric pathogens
MeSH headings : Magnetic Resonance Spectroscopy / methods; Molecular Docking Simulation; Protein Binding; Protein Interaction Mapping / methods; Proteins / chemistry; Thermodynamics
Source: ORCID
Added: December 10, 2019

2014 journal article

Correction to Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force

Biochemistry, 53(39), 6286–6286.

By: C. Tolbert, P. Thompson*, R. Superfine, K. Burridge* & S. Campbell*

co-author countries: Italy 🇮🇹 Russian Federation 🇷🇺
Source: ORCID
Added: December 10, 2019

2014 journal article

Identification of an Actin Binding Surface on Vinculin that Mediates Mechanical Cell and Focal Adhesion Properties

Structure, 22(5), 697–706.

By: P. Thompson*, C. Tolbert*, K. Shen*, P. Kota*, S. Palmer*, K. Plevock*, A. Orlova*, V. Galkin* ...

MeSH headings : Actins / metabolism; Animals; Avian Proteins / chemistry; Avian Proteins / genetics; Avian Proteins / metabolism; Binding Sites; Cells, Cultured; Fibroblasts / cytology; Focal Adhesions; Hydrophobic and Hydrophilic Interactions; Mice; Microscopy, Electron / methods; Models, Molecular; Point Mutation; Rabbits; Vinculin / chemistry; Vinculin / genetics; Vinculin / metabolism
Source: ORCID
Added: December 10, 2019

2014 journal article

Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force

Biochemistry, 53(34), 5526–5536.

By: C. Tolbert*, P. Thompson*, R. Superfine*, K. Burridge* & S. Campbell*

MeSH headings : Actins / chemistry; Animals; Cells, Cultured; Circular Dichroism; Magnetic Resonance Spectroscopy; Mice; Microscopy, Fluorescence; Mutation; Phosphorylation; Protein Binding; Vinculin / chemistry; Vinculin / genetics; Vinculin / physiology
Source: ORCID
Added: December 10, 2019

2014 journal article

SketchBio: a scientist’s 3D interface for molecular modeling and animation

BMC Bioinformatics, 15(1).

By: S. Waldon*, P. Thompson*, P. Hahn* & R. Taylor*

author keywords: Molecular modelling; Animation; Collision detection
MeSH headings : Computer Simulation; Humans; Models, Molecular; Molecular Conformation; Software
Sources: Crossref, ORCID
Added: January 4, 2020

2013 journal article

Combined computational design of a zinc-binding site and a protein-protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding

Proteins, 81(9), 1678–1679.

By: B. Der*, R. Jha*, S. Lewis*, P. Thompson*, G. Guntas* & B. Kuhlman*

Source: ORCID
Added: December 10, 2019

2013 journal article

Combined computational design of a zinc-binding site and a protein-protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding

Proteins: Structure, Function, and Bioinformatics, 81(7), 1245–1255.

By: B. Der*, R. Jha*, S. Lewis*, P. Thompson*, G. Guntas* & B. Kuhlman*

author keywords: computational interface design; de novo; heterodimer; metal coordination; zinc binding; protein-protein interaction
MeSH headings : Alanine / chemistry; Binding Sites; Magnetic Resonance Spectroscopy; Mutagenesis; Protein Binding; Protein Interaction Maps; Ubiquitin / chemistry; Zinc / chemistry
Sources: ORCID, Crossref
Added: December 10, 2019

2013 journal article

Vinculin and metavinculin: Oligomerization and interactions with F-actin

FEBS Letters, 587(8), 1220–1229.

By: P. Thompson*, C. Tolbert* & S. Campbell*

author keywords: Vinculin; Metavinculin; Actin; PIP2; Oligomerization
MeSH headings : Actin Cytoskeleton / chemistry; Actin Cytoskeleton / metabolism; Actins / chemistry; Actins / metabolism; Humans; Models, Molecular; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Vinculin / chemistry; Vinculin / genetics; Vinculin / metabolism
Source: ORCID
Added: December 10, 2019

2013 journal article

Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

J Cell Biol, 202(1), 163–177.

By: I. Thievessen*, P. Thompson*, S. Berlemont*, K. Plevock*, S. Plotnikov*, A. Zemljic-Harpf*, R. Ross*, M. Davidson* ...

MeSH headings : Actins / metabolism; Amino Acid Substitution; Animals; Cell Movement; Cloning, Molecular; Extracellular Matrix / metabolism; Fibroblasts / metabolism; Focal Adhesions / genetics; Focal Adhesions / metabolism; Green Fluorescent Proteins / metabolism; Mice; Mice, Inbred C57BL; Point Mutation; Protein Binding; Protein Interaction Mapping / methods; Protein Transport; Proteolysis; Pseudopodia / metabolism; Vinculin / genetics; Vinculin / metabolism
Source: ORCID
Added: December 10, 2019

2008 journal article

Phthalate induction of CYP3A4 is dependent on glucocorticoid regulation of PXR expression

TOXICOLOGICAL SCIENCES, 103(2), 268–277.

By: B. Cooper n, T. Cho n, P. Thompson n & A. Wallace n

author keywords: pregnane X receptor; CYP3A4; DEHP; MEHP; glucocorticoid
MeSH headings : Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 CYP3A / biosynthesis; Dexamethasone / pharmacology; Diethylhexyl Phthalate / analogs & derivatives; Diethylhexyl Phthalate / toxicity; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction / drug effects; Glucocorticoids / pharmacology; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Plasticizers / toxicity; Pregnane X Receptor; Rats; Receptors, Steroid / drug effects; Receptors, Steroid / metabolism; Transcription, Genetic / drug effects; Transfection
Sources: ORCID, Web Of Science
Added: August 6, 2018

Employment

Updated: June 21st, 2023 11:48

2019 - present

North Carolina State University Raleigh, North Carolina, US
Adjunct Research Assistant Professor Molecular and Structural Biochemistry

2018 - present

North Carolina State University Raleigh, NC, US
Lead Research Scientist Molecular Education, Technology, Research and Innovation Center (METRIC)

2017 - 2019

North Carolina State University Raleigh, North Carolina, US
Principal Research Scholar Biochemistry

2015 - 2017

National Institute of Environmental Health Sciences NC, NC, US
Postdoctoral Fellow Genome Integrity and Structural Biology

Education

Updated: April 30th, 2021 12:16

2008 - 2015

University of North Carolina at Chapel Hill Chapel Hill, NC, US
PhD Candidate Biochemistry and Biophysics

2004 - 2008

North Carolina State University Raleigh, NC, US
B.S. Biochemistry

Funding History

Funding history based on the linked ORCID record. Updated: December 10th, 2019 14:26

grant July 1, 2012 - June 30, 2014
Vinculin Tail Allostery in F-actin Interactions and Implications for Response to Mechanical Force
American Heart Association

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.