Works (20)

2019 journal article

Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1

Scientific Reports, 9(1).

By: A. Foo, P. Thompson, L. Perera, S. Arora, E. DeRose, J. Williams, G. Mueller

Source: ORCID
Added: December 10, 2019

2019 conference paper

Influence of Hydrophobic Cargo Binding on the Structure, Stability, and Allergenicity of the Cockroach Allergen Bla g 1

Journal of Allergy and Clinical Immunology.

Source: ORCID
Added: December 10, 2019

2019 journal article

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity

Allergy.

Source: ORCID
Added: December 10, 2019

2017 journal article

A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization

Structure.

Source: ORCID
Added: December 10, 2019

2017 conference paper

Role of PIP2-Dependent Membrane Interactions in Vinculin Activation, Motility and Force Transmission

Biophysical Journal.

Source: ORCID
Added: December 10, 2019

2016 journal article

A metabolomic, geographic, and seasonal analysis of the contribution of pollen-derived adenosine to allergic sensitization

Metabolomics.

Source: ORCID
Added: December 10, 2019

2016 journal article

Role of PIP2-Dependent Membrane Interactions in Vinculin Activation, Motility and Force Transmission

Biophysical Journal, 110(3), 575a.

By: S. Campbell, P. Thompson, C. Tolbert, L. Case, S. Ramachandran, M. Pershad, N. Dokholyan, K. Burridge, C. Waterman

Source: ORCID
Added: December 10, 2019

2016 journal article

The Structural Basis of Actin Organization by Vinculin and Metavinculin

Journal of Molecular Biology, 428(1), 10–25.

By: L. Kim, P. Thompson, H. Lee, M. Pershad, S. Campbell & G. Alushin

Source: ORCID
Added: December 10, 2019

2015 article

MDFF model of the vinculin tail domain bound to F-actin

Kim, L. Y., Thompson, P. M., Lee, H. T., Pershad, M., Campbell, S. L., & Alushin, G. M. (2015, November 4).

By: L. Kim, P. Thompson, H. Lee, M. Pershad, S. Campbell & G. Alushin

Source: ORCID
Added: December 10, 2019

2015 journal article

New Models for Regulation of Vinculin by Actin and Phospholipids

Biophysical Journal, 108(2), 508a–509a.

By: P. Thompson, H. Lee, L. Kim, S. Ramachandran, A. Tandon, R. Mendez-Giraldez, G. Alushin, N. Dokholyan, S. Campbell

Source: ORCID
Added: December 10, 2019

2015 article

Protein-Protein Interaction Analysis by Nuclear Magnetic Resonance Spectroscopy

Protein-Protein Interactions, pp. 267–279.

By: P. Thompson, M. Beck & S. Campbell

Source: ORCID
Added: December 10, 2019

2014 journal article

Correction to Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force

Biochemistry, 53(39), 6286–6286.

By: C. Tolbert, P. Thompson, R. Superfine, K. Burridge & S. Campbell

Source: ORCID
Added: December 10, 2019

2014 journal article

Identification of an Actin Binding Surface on Vinculin that Mediates Mechanical Cell and Focal Adhesion Properties

Structure, 22(5), 697–706.

By: P. Thompson, C. Tolbert, K. Shen, P. Kota, S. Palmer, K. Plevock, A. Orlova, V. Galkin ...

Source: ORCID
Added: December 10, 2019

2014 journal article

Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force

Biochemistry, 53(34), 5526–5536.

By: C. Tolbert, P. Thompson, R. Superfine, K. Burridge & S. Campbell

Source: ORCID
Added: December 10, 2019

2014 journal article

SketchBio: a scientist’s 3D interface for molecular modeling and animation

BMC Bioinformatics, 15(1).

By: S. Waldon, P. Thompson, P. Hahn & R. Taylor

Sources: Crossref, ORCID
Added: January 4, 2020

2013 journal article

Combined computational design of a zinc-binding site and a protein-protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding

Proteins, 81(9), 1678–1679.

By: B. Der, R. Jha, S. Lewis, P. Thompson, G. Guntas & B. Kuhlman

Source: ORCID
Added: December 10, 2019

2013 journal article

Combined computational design of a zinc-binding site and a protein-protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding

Proteins: Structure, Function, and Bioinformatics, 81(7), 1245–1255.

By: B. Der, R. Jha, S. Lewis, P. Thompson, G. Guntas & B. Kuhlman

Sources: ORCID, Crossref
Added: December 10, 2019

2013 journal article

Vinculin and metavinculin: Oligomerization and interactions with F-actin

FEBS Letters, 587(8), 1220–1229.

By: P. Thompson, C. Tolbert & S. Campbell

Source: ORCID
Added: December 10, 2019

2013 journal article

Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

J Cell Biol, 202(1), 163–177.

By: I. Thievessen, P. Thompson, S. Berlemont, K. Plevock, S. Plotnikov, A. Zemljic-Harpf, R. Ross, M. Davidson ...

Source: ORCID
Added: December 10, 2019

2008 journal article

Phthalate Induction of CYP3A4 is Dependent on Glucocorticoid Regulation of PXR Expression

Toxicological Sciences, 103(2), 268–277.

By: B. Cooper, T. Cho, P. Thompson & A. Wallace

Source: ORCID
Added: December 10, 2019

Employment

2017 - present

North Carolina State University Raleigh, NC, US
Lead Research Scientist Molecular Education, Technology, Research and Innovation Center (METRIC)

2015 - 2017

National Institute of Environmental Health Sciences NC, NC, US
Postdoctoral Fellow Genome Integrity and Structural Biology

Education

2008 - present

University of North Carolina at Chapel Hill Chapel Hill, NC, US
PhD Candidate Biochemistry and Biophysics

2004 - 2008

North Carolina State University Raleigh, NC, US
B.S. Biochemistry

Funding History

Funding history based on the linked ORCID record.

grant July 1, 2012 - June 30, 2014
Vinculin Tail Allostery in F-actin Interactions and Implications for Response to Mechanical Force
American Heart Association