Philip Rocco Miller

Works (17)

Updated: July 8th, 2023 21:14

2019 journal article

Fabrication of Hollow Metal Microneedle Arrays Using a Molding and Electroplating Method

MRS ADVANCES, 4(24), 1417–1426.

By: P. Miller*, M. Moorman*, R. Boehm n, S. Wolfley *, V. Chavez*, J. Baca *, C. Ashley, I. Brener *, R. Narayan n, R. Polsku

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 4, 2019

2015 journal article

Electrodeposited Iron as a Biocompatible Material for Microneedle Fabrication

ELECTROANALYSIS, 27(9), 2239–2249.

By: P. Miller n, R. Boehm n, S. Skoog n, T. Edwards*, M. Rodriguez *, S. Brozik*, I. Brener *, T. Byrd* ...

author keywords: Microneedle; Electroplating; Coating; Iron
TL;DR: Iron coatings proved to significantly improve the strength of the hollow polymer microneedles and sustained structural integrity up to 7 insertions into porcine skin without bending. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Inkjet printing for pharmaceutical applications

MATERIALS TODAY, 17(5), 247–252.

By: R. Boehm n, P. Miller n, J. Daniels*, S. Stafslien* & R. Narayan n

TL;DR: Piezoelectric inkjet printing may be used to load microneedles and other drug delivery devices with pharmacologic agents and showed biodegradation and antifungal activity against the organism Candida albicans on Sabouraud dextrose agar using an in vitro agar plating method. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Microneedle-Based Transdermal Sensor for On-Chip Potentiometric Determination of K+

ADVANCED HEALTHCARE MATERIALS, 3(6), 876–881.

By: P. Miller n, X. Xiao*, I. Brener *, D. Burckel*, R. Narayan n & R. Polsky*

MeSH headings : Biosensing Techniques; Carbon / chemistry; Electrochemical Techniques / instrumentation; Graphite / chemistry; Ion-Selective Electrodes; Ions / chemistry; Microfluidic Analytical Techniques; Porosity; Potassium / analysis
TL;DR: 3D porous carbon and 3D porous graphene electrodes, made via interference lithography, are compared as solid‐state transducers for ISE's and evaluated for electrochemical performance, stability, and selectivity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Microneedle-based self-powered glucose sensor

Electrochemistry Communications, 47, 58–62.

By: G. Valdés-Ramírez *, Y. Li*, J. Kim *, W. Jia *, A. Bandodkar* , R. Nuñez-Flores*, P. Miller n, S. Wu * ...

Contributors: G. Valdés-Ramírez *, Y. Li*, J. Kim *, W. Jia *, A. Bandodkar* , R. Nuñez-Flores*, P. Miller n, S. Wu * ...

author keywords: Microneedle array; Glucose; Self-powered sensor; Biofuel cell
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Simultaneous Detection of Dopamine, Ascorbic Acid and Uric Acid at Lithographically-Defined 3D Graphene Electrodes

ELECTROANALYSIS, 26(1), 52–56.

By: X. Xiao*, P. Miller n, R. Narayan n, S. Brozik*, D. Wheeler*, I. Brener *, J. Wang *, D. Burckel*, R. Polsky*

author keywords: Dopamine; Ascorbic acid; Uric acid; Graphene electrodes
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 article

Antimicrobial activity of biopolymer-antibiotic thin films fabricated by advanced pulsed laser methods

Cristescu, R., Popescu, C., Dorcioman, G., Miroiu, F. M., Socol, G., Mihailescu, I. N., … Chrisey, D. B. (2013, August 1). APPLIED SURFACE SCIENCE, Vol. 278, pp. 211–213.

By: R. Cristescu *, C. Popescu*, G. Dorcioman *, F. Miroiu*, G. Socol *, I. Mihailescu*, S. Gittard n, P. Miller n ...

author keywords: Poly(D,L-lactide); Gentamicin; Matrix assisted pulsed laser evaporation; Drug delivery; Antimicrobial activity
TL;DR: The studies indicate that polymer–drug composite thin films prepared by MAPLE may be used to impart antimicrobial activity to implants, medical devices, and other contact surfaces. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Inkjet Printing of Amphotericin B onto Biodegradable Microneedles Using Piezoelectric Inkjet Printing

JOM, 65(4), 525–533.

By: R. Boehm n, P. Miller n, W. Schell*, J. Perfect * & R. Narayan n

TL;DR: Results of this study suggest that a combination of visible light dynamic mask microstereolithography, micromolding, and piezoelectric inkjet printing may be used to prepare amphotericin B-loaded microneedles with antifungal properties. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Indirect rapid prototyping of antibacterial acid anhydride copolymer microneedles

BIOFABRICATION, 4(1).

By: R. Boehm n, P. Miller n, R. Singh  n, A. Shah, S. Stafslien*, J. Daniels*, R. Narayan n

MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biotechnology / instrumentation; Biotechnology / methods; Candida albicans / drug effects; Elastic Modulus; Maleates / chemistry; Maleates / pharmacology; Manufactured Materials; Needles; Polyvinyls / chemistry; Polyvinyls / pharmacology
TL;DR: The performance of Gantrez® AN 169 BF against several bacteria suggests that biodegradable acid anhydride copolymer microneedle arrays prepared using visible light dynamic mask micro-stereolithography micromolding may be useful for treating a variety of skin infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Multiplexed microneedle-based biosensor array for characterization of metabolic acidosis

TALANTA, 88, 739–742.

By: P. Miller n, S. Skoog n, T. Edwards*, D. Lopez*, D. Wheeler*, D. Arango*, X. Xiao*, S. Brozik* ...

author keywords: Microneedle biosensor; Microneedle; Multiplexed detection; Tumor microenvironment; Carbon paste
MeSH headings : Acidosis / diagnosis; Acidosis / metabolism; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Carbon; Cell Adhesion; Coated Materials, Biocompatible; Electrochemical Techniques; Exercise; Glucose / metabolism; Glucose Oxidase / metabolism; Humans; Hydrogen-Ion Concentration; Lactic Acid / analysis; Lactic Acid / biosynthesis; Macrophages / physiology; Microelectrodes; Needles
TL;DR: Simultaneous and selective amperometric detection of pH, glucose, and lactate over a range of physiologically relevant concentrations in complex media is demonstrated and materials modified with a cell-resistant (Lipidure(®)) coating were shown to inhibit macrophage adhesion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 article

Deposition of antibacterial of poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80/gentamicin sulfate composite coatings by MAPLE

Cristescu, R., Popescu, C., Socol, G., Visan, A., Mihailescu, I. N., Gittard, S. D., … Chrisey, D. B. (2011, April 1). APPLIED SURFACE SCIENCE, Vol. 257, pp. 5287–5292.

By: R. Cristescu *, C. Popescu*, G. Socol *, A. Visan *, I. Mihailescu*, S. Gittard n, P. Miller n, T. Martin n ...

author keywords: Poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80; Gentamicin; Matrix assisted pulsed laser evaporation; Drug delivery
TL;DR: The studies indicate that deposition of polymer–drug composite thin films prepared by MAPLE is a suitable technique for performing controlled drug delivery and may be used to fabricate thin films of good morphological quality. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Deposition of antimicrobial coatings on microstereolithography-fabricated microneedles

JOM, 63(6), 59–68.

By: S. Gittard n, P. Miller n, C. Jin n, T. Martin n, R. Boehm n, B. Chisholm*, S. Stafslien*, J. Daniels* ...

Contributors: S. Gittard n, P. Miller n, C. Jin n, T. Martin n, R. Boehm n, B. Chisholm*, S. Stafslien*, J. Daniels* ...

TL;DR: It is indicated that light-based technologies, including visible light dynamic mask microstereolithography and pulsed laser deposition, may be used to fabricate microneedles with antimicrobial properties for treatment of local skin infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Microneedle array-based carbon paste amperometric sensors and biosensors

ANALYST, 136(9), 1846–1851.

By: J. Windmiller*, N. Zhou *, M. Chuang *, G. Valdes-Ramirez *, P. Santhosh*, P. Miller n, R. Narayan n, J. Wang *

MeSH headings : Acetaminophen / analysis; Ascorbic Acid / analysis; Biofouling; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Carbon / chemistry; Catalysis; Electrochemical Techniques / methods; Glucose / analysis; Hydrogen Peroxide / analysis; Lactic Acid / analysis; Microelectrodes; Transducers; Uric Acid / analysis
TL;DR: The design and characterization of a microneedle array-based carbon paste electrode towards minimally invasive electrochemical sensing are described and the operational stability of the array is demonstrated as well as the interference-free detection of lactate in the presence of physiologically relevant levels of ascorbic acid, uric Acid, and acetaminophen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Modification of microneedles using inkjet printing

AIP Advances, 1(2), 022139.

By: R. Boehm n, P. Miller n, S. Hayes n, N. Monteiro-Riviere n  & R. Narayan n

Contributors: R. Boehm n, P. Miller n, S. Hayes n, N. Monteiro-Riviere n  & R. Narayan n

TL;DR: The results suggest that the combination of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing enables fabrication of solid biodegradable microneedles with a widerange of geometries as well as a wide range of pharmacologic agent compositions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles

FARADAY DISCUSSIONS, 149, 171–185.

By: S. Gittard n, P. Miller n, R. Boehm n, A. Ovsianikov *, B. Chichkov *, J. Heiser*, J. Gordon*, N. Monteiro-Riviere n , R. Narayan n

Contributors: S. Gittard n, P. Miller n, R. Boehm n, A. Ovsianikov *, B. Chichkov *, J. Heiser*, J. Gordon*, N. Monteiro-Riviere n , R. Narayan n

MeSH headings : Administration, Cutaneous; Animals; Drug Delivery Systems / instrumentation; Female; Humans; Infant, Newborn; Keratinocytes / chemistry; Microinjections / methods; Microscopy, Fluorescence; Needles; Polymers / chemistry; Quantum Dots; Skin / chemistry; Skin / cytology; Swine
TL;DR: In this study, microneedle devices for transdermal drug delivery were fabricated by means of two-photon polymerization of an acrylate-based polymer to examine proliferation of cells on this polymer using neonatal human epidermal keratinocytes and human dermal fibroblasts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Microreplication of laser-fabricated surface and three-dimensional structures

JOURNAL OF OPTICS, 12(12).

By: A. Koroleva *, S. Schlie*, E. Fadeeva*, S. Gittard n, P. Miller n, A. Ovsianikov *, J. Koch*, R. Narayan n, B. Chichkov *

author keywords: microreplication; indirect rapid prototyping; soft lithography; femtosecond lasers; two-photon polymerization; biomedical engineering
TL;DR: Any laser-generated surface topography as well as three-dimensional structures can be replicated in various materials without losing the original geometry and it is demonstrated that microstructures have strong influence on morphology and localization of fibroblasts whereas neuroblastoma cells are not negatively affected. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Laser micromachining for biomedical applications

JOM, 61(9), 35–40.

By: P. Miller n, R. Aggarwal n, A. Doraiswamy n, Y. Lin *, Y. Lee n  & R. Narayan n

TL;DR: In vitro studies showed that microscale grooves on silicon substrates may be used to orient human aortic vascular smooth muscle cells, and it is anticipated that the use of laser micromachining for modifying medical and dental devices will become more significant over the coming years. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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