Philip Rocco Miller

Works (17)

Updated: July 8th, 2023 21:14

2019 article

Fabrication of Hollow Metal Microneedle Arrays Using a Molding and Electroplating Method

Miller, P. R., Moorman, M., Boehm, R. D., Wolfley, S., Chavez, V., Baca, J. T., … Polsky, R. (2019, March 14). MRS Advances.

By: P. Miller*, M. Moorman*, R. Boehm n, S. Wolfley *, V. Chavez*, J. Baca *, C. Ashley, I. Brener *, R. Narayan n, R. Polsky*

topics (OpenAlex): Advancements in Transdermal Drug Delivery; Neuroscience and Neural Engineering; Advanced Fluorescence Microscopy Techniques
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 4, 2019

2015 article

Electrodeposited Iron as a Biocompatible Material for Microneedle Fabrication

Miller, P. R., Boehm, R. D., Skoog, S. A., Edwards, T. L., Rodriguez, M., Brozik, S., … Polsky, R. (2015, July 23). Electroanalysis.

By: P. Miller n, R. Boehm n, S. Skoog n, T. Edwards*, M. Rodriguez *, S. Brozik*, I. Brener *, T. Byrd * ...

author keywords: Microneedle; Electroplating; Coating; Iron
topics (OpenAlex): Advancements in Transdermal Drug Delivery; Contact Dermatitis and Allergies; Plant Surface Properties and Treatments
TL;DR: Iron coatings proved to significantly improve the strength of the hollow polymer microneedles and sustained structural integrity up to 7 insertions into porcine skin without bending. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 article

Inkjet printing for pharmaceutical applications

Boehm, R. D., Miller, P. R., Daniels, J., Stafslien, S., & Narayan, R. J. (2014, May 2). Materials Today.

By: R. Boehm n, P. Miller n, J. Daniels*, S. Stafslien* & R. Narayan n

topics (OpenAlex): Advancements in Transdermal Drug Delivery; 3D Printing in Biomedical Research; Nanofabrication and Lithography Techniques
TL;DR: Piezoelectric inkjet printing may be used to load microneedles and other drug delivery devices with pharmacologic agents and showed biodegradation and antifungal activity against the organism Candida albicans on Sabouraud dextrose agar using an in vitro agar plating method. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Microneedle-based self-powered glucose sensor

Electrochemistry Communications, 47, 58–62.

By: G. Valdés-Ramírez *, Y. Li*, J. Kim *, W. Jia *, A. Bandodkar* , R. Nuñez-Flores *, P. Miller n, S. Wu * ...

Contributors: G. Valdés-Ramírez *, Y. Li*, J. Kim *, W. Jia *, A. Bandodkar* , R. Nuñez-Flores *, P. Miller n, S. Wu * ...

author keywords: Microneedle array; Glucose; Self-powered sensor; Biofuel cell
topics (OpenAlex): Electrochemical sensors and biosensors; Neuroscience and Neural Engineering; Lipid Membrane Structure and Behavior
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2013 article

Antimicrobial activity of biopolymer–antibiotic thin films fabricated by advanced pulsed laser methods

Cristescu, R., Popescu, C., Dorcioman, G., Miroiu, F. M., Socol, G., Mihailescu, I. N., … Chrisey, D. B. (2013, January 18). Applied Surface Science.

By: R. Cristescu *, C. Popescu *, G. Dorcioman *, F. Miroiu*, G. Socol *, I. Mihailescu *, S. Gittard n, P. Miller n ...

author keywords: Poly(D,L-lactide); Gentamicin; Matrix assisted pulsed laser evaporation; Drug delivery; Antimicrobial activity
topics (OpenAlex): Dental materials and restorations; 3D Printing in Biomedical Research; Antimicrobial agents and applications
TL;DR: The studies indicate that polymer–drug composite thin films prepared by MAPLE may be used to impart antimicrobial activity to implants, medical devices, and other contact surfaces. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 article

Inkjet Printing of Amphotericin B onto Biodegradable Microneedles Using Piezoelectric Inkjet Printing

Boehm, R. D., Miller, P. R., Schell, W. A., Perfect, J. R., & Narayan, R. J. (2013, February 21). JOM.

By: R. Boehm n, P. Miller n, W. Schell*, J. Perfect * & R. Narayan n

topics (OpenAlex): Advancements in Transdermal Drug Delivery; Bee Products Chemical Analysis; 3D Printing in Biomedical Research
TL;DR: Results of this study suggest that a combination of visible light dynamic mask microstereolithography, micromolding, and piezoelectric inkjet printing may be used to prepare amphotericin B-loaded microneedles with antifungal properties. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 article

Microneedle‐Based Transdermal Sensor for On‐Chip Potentiometric Determination of K+

Miller, P. R., Xiao, X., Brener, I., Burckel, D. B., Narayan, R., & Polsky, R. (2013, December 21). Advanced Healthcare Materials.

By: P. Miller n, X. Xiao*, I. Brener *, D. Burckel *, R. Narayan n & R. Polsky*

MeSH headings : Biosensing Techniques; Carbon / chemistry; Electrochemical Techniques / instrumentation; Graphite / chemistry; Ion-Selective Electrodes; Ions / chemistry; Microfluidic Analytical Techniques; Porosity; Potassium / analysis
topics (OpenAlex): Analytical Chemistry and Sensors; Electrochemical sensors and biosensors; Electrochemical Analysis and Applications
TL;DR: 3D porous carbon and 3D porous graphene electrodes, made via interference lithography, are compared as solid‐state transducers for ISE's and evaluated for electrochemical performance, stability, and selectivity. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 article

Simultaneous Detection of Dopamine, Ascorbic Acid and Uric Acid at Lithographically‐Defined 3D Graphene Electrodes

Xiao, X., Miller, P. R., Narayan, R. J., Brozik, S. M., Wheeler, D. R., Brener, I., … Polsky, R. (2013, August 28). Electroanalysis.

By: X. Xiao*, P. Miller n, R. Narayan n, S. Brozik*, D. Wheeler*, I. Brener *, J. Wang *, D. Burckel *, R. Polsky*

author keywords: Dopamine; Ascorbic acid; Uric acid; Graphene electrodes
topics (OpenAlex): Electrochemical sensors and biosensors; Electrochemical Analysis and Applications; Conducting polymers and applications
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2012 article

Indirect rapid prototyping of antibacterial acid anhydride copolymer microneedles

Boehm, R. D., Miller, P. R., Singh, R., Shah, A., Stafslien, S., Daniels, J., & Narayan, R. J. (2012, January 30). Biofabrication.

By: R. Boehm*, P. Miller n, R. Singh n, A. Shah, S. Stafslien*, J. Daniels*, R. Narayan n

MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biotechnology / instrumentation; Biotechnology / methods; Candida albicans / drug effects; Elastic Modulus; Maleates / chemistry; Maleates / pharmacology; Manufactured Materials; Needles; Polyvinyls / chemistry; Polyvinyls / pharmacology
topics (OpenAlex): Advancements in Transdermal Drug Delivery; Bee Products Chemical Analysis; Dermatology and Skin Diseases
TL;DR: The performance of Gantrez® AN 169 BF against several bacteria suggests that biodegradable acid anhydride copolymer microneedle arrays prepared using visible light dynamic mask micro-stereolithography micromolding may be useful for treating a variety of skin infections. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 article

Deposition of antimicrobial coatings on microstereolithography-fabricated microneedles

Gittard, S. D., Miller, P. R., Jin, C., Martin, T. N., Boehm, R. D., Chisholm, B. J., … Narayan, R. J. (2011, June 1). JOM, Vol. 63, pp. 59–68.

By: S. Gittard n, P. Miller n, C. Jin n, T. Martin n, R. Boehm n, B. Chisholm *, S. Stafslien*, J. Daniels* ...

Contributors: S. Gittard n, P. Miller n, C. Jin n, T. Martin n, R. Boehm n, B. Chisholm *, S. Stafslien*, J. Daniels* ...

topics (OpenAlex): Advancements in Transdermal Drug Delivery; Dermatology and Skin Diseases; Contact Dermatitis and Allergies
TL;DR: It is indicated that light-based technologies, including visible light dynamic mask microstereolithography and pulsed laser deposition, may be used to fabricate microneedles with antimicrobial properties for treatment of local skin infections. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 article

Microneedle array-based carbon paste amperometric sensors and biosensors

Windmiller, J. R., Zhou, N., Chuang, M.-C., Valdés-Ramírez, G., Santhosh, P., Miller, P. R., … Wang, J. (2011, January 1). The Analyst.

By: J. Windmiller*, N. Zhou *, M. Chuang *, G. Valdés-Ramírez *, P. Santhosh *, P. Miller n, R. Narayan n, J. Wang *

MeSH headings : Acetaminophen / analysis; Ascorbic Acid / analysis; Biofouling; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Carbon / chemistry; Catalysis; Electrochemical Techniques / methods; Glucose / analysis; Hydrogen Peroxide / analysis; Lactic Acid / analysis; Microelectrodes; Transducers; Uric Acid / analysis
topics (OpenAlex): Advancements in Transdermal Drug Delivery; Electrochemical sensors and biosensors; Advanced Chemical Sensor Technologies
TL;DR: The design and characterization of a microneedle array-based carbon paste electrode towards minimally invasive electrochemical sensing are described and the operational stability of the array is demonstrated as well as the interference-free detection of lactate in the presence of physiologically relevant levels of ascorbic acid, uric Acid, and acetaminophen. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Modification of microneedles using inkjet printing

AIP Advances, 1(2), 022139.

By: R. Boehm n, P. Miller n, S. Hayes  n, N. Monteiro-Riviere n  & R. Narayan n

Contributors: R. Boehm n, P. Miller n, S. Hayes  n, N. Monteiro-Riviere n  & R. Narayan n

topics (OpenAlex): Advancements in Transdermal Drug Delivery; Advanced Fluorescence Microscopy Techniques; Nanofabrication and Lithography Techniques
TL;DR: The results suggest that the combination of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing enables fabrication of solid biodegradable microneedles with a widerange of geometries as well as a wide range of pharmacologic agent compositions. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 article

Multiplexed microneedle-based biosensor array for characterization of metabolic acidosis

Miller, P. R., Skoog, S. A., Edwards, T. L., Lopez, D. M., Wheeler, D. R., Arango, D. C., … Narayan, R. J. (2011, November 22). Talanta.

By: P. Miller n, S. Skoog n, T. Edwards*, D. Lopez*, D. Wheeler*, D. Arango*, X. Xiao*, S. Brozik* ...

author keywords: Microneedle biosensor; Microneedle; Multiplexed detection; Tumor microenvironment; Carbon paste
MeSH headings : Acidosis / diagnosis; Acidosis / metabolism; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Carbon; Cell Adhesion; Coated Materials, Biocompatible; Electrochemical Techniques; Exercise; Glucose / metabolism; Glucose Oxidase / metabolism; Humans; Hydrogen-Ion Concentration; Lactic Acid / analysis; Lactic Acid / biosynthesis; Macrophages / physiology; Microelectrodes; Needles
topics (OpenAlex): Analytical Chemistry and Sensors; Lipid Membrane Structure and Behavior; Advancements in Transdermal Drug Delivery
TL;DR: Simultaneous and selective amperometric detection of pH, glucose, and lactate over a range of physiologically relevant concentrations in complex media is demonstrated and materials modified with a cell-resistant (Lipidure(®)) coating were shown to inhibit macrophage adhesion. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 article

Deposition of antibacterial of poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80/gentamicin sulfate composite coatings by MAPLE

Cristescu, R., Popescu, C., Socol, G., Visan, A., Mihailescu, I. N., Gittard, S. D., … Chrisey, D. B. (2010, December 8). Applied Surface Science.

By: R. Cristescu *, C. Popescu *, G. Socol *, A. Visan *, I. Mihailescu *, S. Gittard n, P. Miller n, T. Martin n ...

author keywords: Poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80; Gentamicin; Matrix assisted pulsed laser evaporation; Drug delivery
topics (OpenAlex): Nanofabrication and Lithography Techniques; Polymer Surface Interaction Studies; Dental materials and restorations
TL;DR: The studies indicate that deposition of polymer–drug composite thin films prepared by MAPLE is a suitable technique for performing controlled drug delivery and may be used to fabricate thin films of good morphological quality. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 article

Microreplication of laser-fabricated surface and three-dimensional structures

Koroleva, A., Schlie, S., Fadeeva, E., Gittard, S. D., Miller, P., Ovsianikov, A., … Chichkov, B. N. (2010, November 11). Journal of Optics.

By: A. Koroleva *, S. Schlie*, E. Fadeeva*, S. Gittard n, P. Miller n, A. Ovsianikov *, J. Koch *, R. Narayan n, B. Chichkov *

author keywords: microreplication; indirect rapid prototyping; soft lithography; femtosecond lasers; two-photon polymerization; biomedical engineering
topics (OpenAlex): Laser Material Processing Techniques; Nonlinear Optical Materials Studies; Cellular Mechanics and Interactions
TL;DR: Any laser-generated surface topography as well as three-dimensional structures can be replicated in various materials without losing the original geometry and it is demonstrated that microstructures have strong influence on morphology and localization of fibroblasts whereas neuroblastoma cells are not negatively affected. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 article

Multiphoton microscopy of transdermal quantum dot delivery using two photonpolymerization-fabricated polymer microneedles

Gittard, S. D., Miller, P. R., Boehm, R. D., Ovsianikov, A., Chichkov, B. N., Heiser, J., … Narayan, R. J. (2010, September 23). Faraday Discussions, Vol. 149, pp. 171–185.

By: S. Gittard n, P. Miller n, R. Boehm  n, A. Ovsianikov *, B. Chichkov *, J. Heiser*, J. Gordon *, N. Monteiro-Riviere n , R. Narayan n

Contributors: S. Gittard n, P. Miller n, R. Boehm  n, A. Ovsianikov *, B. Chichkov *, J. Heiser*, J. Gordon *, N. Monteiro-Riviere n , R. Narayan n

MeSH headings : Administration, Cutaneous; Animals; Drug Delivery Systems / instrumentation; Female; Humans; Infant, Newborn; Keratinocytes / chemistry; Microinjections / methods; Microscopy, Fluorescence; Needles; Polymers / chemistry; Quantum Dots; Skin / chemistry; Skin / cytology; Swine
topics (OpenAlex): Advancements in Transdermal Drug Delivery; Advanced Fluorescence Microscopy Techniques; Nonlinear Optical Materials Studies
TL;DR: In this study, microneedle devices for transdermal drug delivery were fabricated by means of two-photon polymerization of an acrylate-based polymer to examine proliferation of cells on this polymer using neonatal human epidermal keratinocytes and human dermal fibroblasts. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 article

Laser micromachining for biomedical applications

Miller, P. R., Aggarwal, R., Doraiswamy, A., Lin, Y. J., Lee, Y.-S., & Narayan, R. J. (2009, September 1). JOM, Vol. 61, pp. 35–40.

By: P. Miller n, R. Aggarwal n, A. Doraiswamy n, Y. Lin*, Y. Lee n  & R. Narayan n

topics (OpenAlex): Laser Material Processing Techniques; Laser Applications in Dentistry and Medicine; Ocular and Laser Science Research
TL;DR: In vitro studies showed that microscale grooves on silicon substrates may be used to orient human aortic vascular smooth muscle cells, and it is anticipated that the use of laser micromachining for modifying medical and dental devices will become more significant over the coming years. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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