Works (29)

Updated: April 11th, 2023 10:13

2019 journal article

Use of a Branched Linker for Enhanced Biosensing Properties in IgG Detection from Mixed Chinese Hamster Ovary Cell Cultures

BIOCONJUGATE CHEMISTRY, 30(3), 815–825.

By: N. Islam, P. Gurgel, O. Rojas & R. Carbonell

Source: Web Of Science
Added: April 9, 2019

2016 journal article

Affinity interactions of human immunoglobulin G with short peptides: role of ligand spacer on binding, kinetics, and mass transfer

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408(7), 1829–1841.

By: F. Shen n, O. Rojas, J. Genzer, P. Gurgel & R. Carbonell

author keywords: Peptide ligands; Immunoglobulin G; Peptide HWRGWV; Spacer arms; Quartz crystal microbalance
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Reducing diffusion limitations in Ion exchange grafted membranes using high surface area nonwovens

JOURNAL OF MEMBRANE SCIENCE, 514, 53–64.

By: M. Heller n, R. Wimbish n, P. Gurgel, B. Pourdeyhimi & R. Carbonell

author keywords: UV grafting; Islands-in-the-sea nonwoven; Diffusion limited; Ion exchange protein capture; Shrinking core
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Preparation and characterization of anion exchange adsorptive nonwoven membranes with high protein binding capacity

JOURNAL OF MEMBRANE SCIENCE, 493, 349–359.

By: H. Liu, P. Gurgel & R. Carbonell

author keywords: Anion exchange membrane; Protein purification; Nonwoven surface modification; High protein binding capacity; hIgG separation
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Dynamic and equilibrium performance of sensors based on short peptide ligands for affinity adsorption of human IgG using surface plasmon resonance

BIOSENSORS & BIOELECTRONICS, 58, 380–387.

By: N. Islam, F. Shen n, P. Gurgel, O. Rojas & R. Carbonell

author keywords: Hexamer; Protein A; Human immunoglobulin G; Self-assembled monolayers; Adsorption rate constant; Desorption rate constant
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Effects of Composition of Oligo(ethylene glycol)-Based Mixed Monolayers on Peptide Grafting and Human Immunoglobulin Detection

JOURNAL OF PHYSICAL CHEMISTRY C, 118(10), 5361–5373.

By: N. Islam, P. Gurgel, O. Rojas & R. Carbonell

Source: Web Of Science
Added: August 6, 2018

2013 journal article

Affinity chromatographic purification of human immunoglobulin M from human B lymphocyte cell culture supernatant

BIOCHEMICAL ENGINEERING JOURNAL, 70, 63–70.

By: Z. Liu, P. Gurgel & R. Carbonell

author keywords: Affinity chromatography; Hexamer peptide; Human immunoglobulin; IgM; Dynamic binding capacity; Elution additive
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Affinity chromatographic purification of human immunoglobulin a from chinese hamster ovary cell culture supernatant

BIOTECHNOLOGY PROGRESS, 29(1), 91–98.

By: Z. Liu, P. Gurgel & R. Carbonell

author keywords: affinity chromatography; hexamer peptide; CHO; human immunoglobulin; secretory IgA
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Alkaline-stable peptide ligand affinity adsorbents for the purification of biomolecules

Journal of Chromatography A, 1245, 55–64.

By: S. Menegatti, A. Naik, P. Gurgel & R. Carbonell

author keywords: Peptide ligand; Affinity adsorbent; NaOH stability; Modification of surface chemistry; Solid-phase peptide synthesis; Cleaning-in-place
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Porcine parvovirus removal using trimer and biased hexamer peptides

Biotechnology Journal, 7(4), 558–565.

By: C. Heldt, P. Gurgel, L. Jaykus & R. Carbonell

author keywords: Affinity adsorption; Biosafety; Bioseparation; Ligand; Virus removal
Sources: Web Of Science, Crossref
Added: August 6, 2018

2012 journal article

Process for purification of monoclonal antibody expressed in transgenic Lemna plant extract using dextran-coated charcoal and hexamer peptide affinity resin

Journal of Chromatography A, 1260, 61–66.

author keywords: Dextran-coated charcoal; Transgenic plants; Hexapeptide ligand; IgG purification; Monoclonal antibody; Phenolics; Lemna minor
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Purification of human immunoglobulins A, G and M from Cohn fraction II/III by small peptide affinity chromatography

JOURNAL OF CHROMATOGRAPHY A, 1262, 169–179.

By: Z. Liu, P. Gurgel & R. Carbonell

author keywords: Hexamer peptide; IVIG; Cohn fraction; Elution additive; PEG; Ammonium sulfate
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Effects of UV Exposure and Initiator Concentration on the Spatial Variation of Poly(glycidyl methacrylate) Grafts on Nonwoven Fabrics

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 50(10), 6115–6123.

By: Y. Zheng*, P. Gurgel & R. Carbonell

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Effects of peptide density and elution pH on affinity chromatographic purification of human immunoglobulins A and M

JOURNAL OF CHROMATOGRAPHY A, 1218(46), 8344–8352.

By: Z. Liu, P. Gurgel & R. Carbonell

author keywords: Human immunoglobulin; IgG; IgA; IgM; Affinity chromatography; Binding site
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media

Journal of Chromatography A, 1218(13), 1691–1700.

By: A. Naik, S. Menegatti, P. Gurgel & R. Carbonell

author keywords: Hexapeptide ligand; IgG purification; Monoclonal antibody; Affinity chromatography; Regeneration
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Binding site on human immunoglobulin G for the affinity ligand HWRGWV

Journal of Molecular Recognition, 23(3), 271–282.

By: H. Yang, P. Gurgel, D. Williams, B. Bobay, J. Cavanagh, D. Muddiman, R. Carbonell

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Purification of human immunoglobulin G via Fc-specific small peptide ligand affinity chromatography

JOURNAL OF CHROMATOGRAPHY A, 1216(6), 910–918.

By: H. Yang, P. Gurgel & R. Carbonell

author keywords: Human immunoglobulin G; Fc fragment; Hexamer peptide ligand; Affinity chromatography; Ligand density
Source: Web Of Science
Added: August 6, 2018

2008 article

Identification of trimeric peptides that bind porcine parvovirus from mixtures containing human blood plasma

BIOTECHNOLOGY PROGRESS, Vol. 24, pp. 554–560.

By: C. Heldt, P. Gurgel, L. Jaykus & R. Carbonell

Source: Web Of Science
Added: August 6, 2018

2008 patent

Prion protein binding materials and methods of use

Washington, DC: U.S. Patent and Trademark Office.

By: R. Carbonell, H. Shen, P. Gurgel, V. Wiltshire-Lyerly, D. Hammond & S. Burton

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

A colorimetric assay for viral agents that produce cytopathic effects

Journal of Virological Methods, 135(1), 56–65.

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Reduction in infectivity of endogenous transmissible spongiform encephalopathies present in blood by adsorption to selective affinity resins

LANCET, 368(9554), 2226–2230.

By: L. Gregori*, P. Gurgel, J. Lathrop*, P. Edwardson*, B. Lambert*, R. Carbonell, S. Burton*, D. Hammond, R. Rohwer*

Source: Web Of Science
Added: August 6, 2018

2006 journal article

Reduction of transmissible spongiform encephalopathy infectivity from human red blood cells with prion protein affinity ligands

TRANSFUSION, 46(7), 1152–1161.

By: L. Gregori*, B. Lambert, P. Gurgel, L. Gheorghiu, P. Edwardson, J. Lathrop, C. MacAuley, R. Carbonell ...

Source: Web Of Science
Added: August 6, 2018

2005 journal article

Hexamer peptide affinity resins that bind the Fc region of human immunoglobulin G

JOURNAL OF PEPTIDE RESEARCH, 66, 120–137.

By: H. Yang, P. Gurgel & R. Carbonell

author keywords: affinity chromatography; Fc fragment; hexapeptide; immunoglobulin
Source: Web Of Science
Added: August 6, 2018

2005 article

Small Peptide Ligands for Affinity Separations of Biological Molecules

CHEMICAL ENGINEERING TRENDS AND DEVELOPMENTS, pp. 63–83.

By: G. Wang n, J. Salm n, P. Gurgel & R. Carbonell

Source: Web Of Science
Added: August 6, 2018

2001 journal article

Identification of peptide ligands generated by combinatorial chemistry that bind alpha-lactalbumin

SEPARATION SCIENCE AND TECHNOLOGY, 36(11), 2411–2431.

By: P. Gurgel, R. Carbonell & H. Swaisgood

Source: Web Of Science
Added: August 6, 2018

2001 journal article

Studies of the binding of alpha-lactalbumin to immobilized peptide ligands

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 49(12), 5765–5770.

By: P. Gurgel, R. Carbonell & H. Swaisgood

author keywords: alpha-lactalbumin; peptide ligands; bioselective adsorption; binding mechanism
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Fractionation of whey proteins with a hexapeptide ligand affinity resin

BIOSEPARATION, 9(6), 385–392.

By: P. Gurgel, R. Carbonell & H. Swaisgood

author keywords: alpha-lactalbumin; bioselective adsorption; peptide ligands; whey protein isolate
Source: Web Of Science
Added: August 6, 2018

patent

Prion protein binding materials and methods of use

Hammond, D. J., Carbonell, R. G., Shen, H., Gurgel, P. V., Wiltshire-Lyerly, V., & Burton, S. J.

By: D. Hammond, R. Carbonell, H. Shen, P. Gurgel, V. Wiltshire-Lyerly & S. Burton

Source: NC State University Libraries
Added: August 6, 2018

patent

Purification of immunoglobulins using affinity chromatography and peptide ligands

Carbonell, R. G., Yang, H., & Gurgel, P. V. Washington, DC: U.S. Patent and Trademark Office.

By: R. Carbonell, H. Yang & P. Gurgel

Source: NC State University Libraries
Added: August 6, 2018