Patrick Gurgel

Islam, N., Gurgel, P. V., Rojas, O. J., & Carbonell, R. G. (2019). Use of a Branched Linker for Enhanced Biosensing Properties in IgG Detection from Mixed Chinese Hamster Ovary Cell Cultures. BIOCONJUGATE CHEMISTRY, 30(3), 815–825. https://doi.org/10.1021/acs.bioconjchem.8b00918

Shen, F., Rojas, O. J., Genzer, J., Gurgel, P. V., & Carbonell, R. G. (2016). Affinity interactions of human immunoglobulin G with short peptides: role of ligand spacer on binding, kinetics, and mass transfer. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408(7), 1829–1841. https://doi.org/10.1007/s00216-015-9135-y

Heller, M., Wimbish, R., Gurgel, P. V., Pourdeyhimi, B., & Carbonell, R. G. (2016). Reducing diffusion limitations in Ion exchange grafted membranes using high surface area nonwovens. JOURNAL OF MEMBRANE SCIENCE, 514, 53–64. https://doi.org/10.1016/j.memsci.2016.02.046

Liu, H., Gurgel, P. V., & Carbonell, R. G. (2015). Preparation and characterization of anion exchange adsorptive nonwoven membranes with high protein binding capacity. JOURNAL OF MEMBRANE SCIENCE, 493, 349–359. https://doi.org/10.1016/j.memsci.2015.06.002

Islam, N., Shen, F., Gurgel, P. V., Rojas, O. J., & Carbonell, R. G. (2014). Dynamic and equilibrium performance of sensors based on short peptide ligands for affinity adsorption of human IgG using surface plasmon resonance. BIOSENSORS & BIOELECTRONICS, 58, 380–387. https://doi.org/10.1016/j.bios.2014.02.069

Islam, N., Gurgel, P. V., Rojas, O. J., & Carbonell, R. G. (2014). Effects of Composition of Oligo(ethylene glycol)-Based Mixed Monolayers on Peptide Grafting and Human Immunoglobulin Detection. JOURNAL OF PHYSICAL CHEMISTRY C, 118(10), 5361–5373. https://doi.org/10.1021/jp411469u

Liu, Z., Gurgel, P. V., & Carbonell, R. G. (2013). Affinity chromatographic purification of human immunoglobulin M from human B lymphocyte cell culture supernatant. BIOCHEMICAL ENGINEERING JOURNAL, 70, 63–70. https://doi.org/10.1016/j.bej.2012.10.003

Liu, Z., Gurgel, P. V., & Carbonell, R. G. (2013). Affinity chromatographic purification of human immunoglobulin a from chinese hamster ovary cell culture supernatant. BIOTECHNOLOGY PROGRESS, 29(1), 91–98. https://doi.org/10.1002/btpr.1652

Menegatti, S., Naik, A. D., Gurgel, P. V., & Carbonell, R. G. (2012). Alkaline-stable peptide ligand affinity adsorbents for the purification of biomolecules. Journal of Chromatography A, 1245, 55–64. https://doi.org/10.1016/j.chroma.2012.04.072

Heldt, C. L., Gurgel, P. V., Jaykus, L.-A., & Carbonell, R. G. (2012). Porcine parvovirus removal using trimer and biased hexamer peptides. Biotechnology Journal, 7(4), 558–565. https://doi.org/10.1002/biot.201000397

Naik, A. D., Menegatti, S., Reese, H. R., Gurgel, P. V., & Carbonell, R. G. (2012). Process for purification of monoclonal antibody expressed in transgenic Lemna plant extract using dextran-coated charcoal and hexamer peptide affinity resin. Journal of Chromatography A, 1260, 61–66. https://doi.org/10.1016/j.chroma.2012.08.043

Liu, Z., Gurgel, P. V., & Carbonell, R. G. (2012). Purification of human immunoglobulins A, G and M from Cohn fraction II/III by small peptide affinity chromatography. JOURNAL OF CHROMATOGRAPHY A, 1262, 169–179. https://doi.org/10.1016/j.chroma.2012.09.026

Zheng, Y., Gurgel, P. V., & Carbonell, R. G. (2011). Effects of UV Exposure and Initiator Concentration on the Spatial Variation of Poly(glycidyl methacrylate) Grafts on Nonwoven Fabrics. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 50(10), 6115–6123. https://doi.org/10.1021/ie1021333

Liu, Z., Gurgel, P. V., & Carbonell, R. G. (2011). Effects of peptide density and elution pH on affinity chromatographic purification of human immunoglobulins A and M. JOURNAL OF CHROMATOGRAPHY A, 1218(46), 8344–8352. https://doi.org/10.1016/j.chroma.2011.09.038

Naik, A. D., Menegatti, S., Gurgel, P. V., & Carbonell, R. G. (2011). Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media. Journal of Chromatography A, 1218(13), 1691–1700. https://doi.org/10.1016/j.chroma.2010.11.071

Yang, H. O., Gurgel, P. V., Williams, D. K., Bobay, B. G., Cavanagh, J., Muddiman, D. C., & Carbonell, R. G. (2010). Binding site on human immunoglobulin G for the affinity ligand HWRGWV. Journal of Molecular Recognition, 23(3), 271–282.

Yang, H., Gurgel, P. V., & Carbonell, R. G. (2009). Purification of human immunoglobulin G via Fc-specific small peptide ligand affinity chromatography. JOURNAL OF CHROMATOGRAPHY A, 1216(6), 910–918. https://doi.org/10.1016/j.chroma.2008.12.004

Heldt, C. L., Gurgel, P. V., Jaykus, L.-A., & Carbonell, R. G. (2008). Identification of trimeric peptides that bind porcine parvovirus from mixtures containing human blood plasma. BIOTECHNOLOGY PROGRESS, Vol. 24, pp. 554–560. https://doi.org/10.1021/bp070412c

Carbonell, R. G., Shen, H., Gurgel, P. V., Wiltshire-Lyerly, V., Hammond, D. J., & Burton, S. J. (2008). Prion protein binding materials and methods of use. Washington, DC: U.S. Patent and Trademark Office.

Heldt, C. L., Hernandez, R., Mudiganti, U., Gurgel, P. V., Brown, D. T., & Carbonell, R. G. (2006). A  colorimetric assay for viral agents that produce cytopathic effects. Journal of Virological Methods, 135(1), 56–65. https://doi.org/10.1016/j.j.viromet.2006.01.022

Gregori, L., Gurgel, P. V., Lathrop, J. T., Edwardson, P., Lambert, B. C., Carbonell, R. G., … Rohwer, R. G. (2006). Reduction in infectivity of endogenous transmissible spongiform encephalopathies present in blood by adsorption to selective affinity resins. LANCET, 368(9554), 2226–2230. https://doi.org/10.1016/S0140-6736(06)69897-8

Gregori, L., Lambert, B. C., Gurgel, P. V., Gheorghiu, L., Edwardson, P., Lathrop, J. T., … Rohwer, R. G. (2006). Reduction of transmissible spongiform encephalopathy infectivity from human red blood cells with prion protein affinity ligands. TRANSFUSION, 46(7), 1152–1161. https://doi.org/10.1111/j.1537-2995.2006.00865.x

Yang, H., Gurgel, P. V., & Carbonell, R. G. (2005). Hexamer peptide affinity resins that bind the Fc region of human immunoglobulin G. JOURNAL OF PEPTIDE RESEARCH, 66, 120–137. https://doi.org/10.1111/j.1747-0285.2006.00342.x

Wang, G., Salm, J. R., Gurgel, P. V., & Carbonell, R. G. (2005). Small Peptide Ligands for Affinity Separations of Biological Molecules. CHEMICAL ENGINEERING TRENDS AND DEVELOPMENTS, pp. 63–83. https://doi.org/10.1002/0470025018.ch3

Gurgel, P. V., Carbonell, R. G., & Swaisgood, H. E. (2001). Identification of peptide ligands generated by combinatorial chemistry that bind alpha-lactalbumin. SEPARATION SCIENCE AND TECHNOLOGY, 36(11), 2411–2431. https://doi.org/10.1081/SS-100106100

Gurgel, P. V., Carbonell, R. G., & Swaisgood, H. E. (2001). Studies of the binding of alpha-lactalbumin to immobilized peptide ligands. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 49(12), 5765–5770. https://doi.org/10.1021/jf010462b

Gurgel, P. V., Carbonell, R. G., & Swaisgood, H. E. (2000). Fractionation of whey proteins with a hexapeptide ligand affinity resin. BIOSEPARATION, 9(6), 385–392. https://doi.org/10.1023/A:1011191818927

Hammond, D. J., Carbonell, R. G., Shen, H., Gurgel, P. V., Wiltshire-Lyerly, V., & Burton, S. J. Prion protein binding materials and methods of use.

Carbonell, R. G., Yang, H., & Gurgel, P. V. Purification of immunoglobulins using affinity chromatography and peptide ligands. Washington, DC: U.S. Patent and Trademark Office.