Paul W. Bernhardt

Works (2)

Updated: July 5th, 2023 15:46

2014 journal article

Flexible modeling of survival data with covariates subject to detection limits via multiple imputation

COMPUTATIONAL STATISTICS & DATA ANALYSIS, 69, 81–91.

By: P. Bernhardt n, H. Wang n & D. Zhang n

author keywords: Accelerated failure time model; Censored predictor; Complete case; Detection limit; Multiple imputation; Seminonparametric distribution
TL;DR: A computationally-efficient multiple imputation procedure for modeling survival data with covariates subject to detection limits is proposed in the context of an accelerated failure time model with a flexible seminonparametric error distribution. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2011 journal article

Quantifying Uncertainty in Predictions of Hepatic Clearance

STATISTICS IN BIOPHARMACEUTICAL RESEARCH, 3(4), 515–525.

By: J. Rogers, J. Wilbur, S. Cole, P. Bernhardt*, J. Bupp, M. Lennon*, N. Langholz, C. Steiner

author keywords: Bayesian; Pharmacokinetics; Preclinical; Translational
TL;DR: This article proposes and evaluates Bayesian models for preclinical and clinical pharmacokinetic experimentation for 12 different anonymized drugs and concludes that many apparent translational differences may be readily explained as a function of experimental error. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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