Works (24)

Updated: July 11th, 2023 21:16

2017 journal article

Toll-like receptor and related cytokine mRNA expression in bovine corpora lutea during the oestrous cycle and pregnancy

REPRODUCTION IN DOMESTIC ANIMALS, 52(3), 495–504.

By: J. Gadsby n, A. Nipper n, H. Faircloth n, . M. D'Annibale-Tolhurst, J. Chang n, P. Farin n, I. Sheldon*, D. Poole n

MeSH headings : Animals; Cattle; Corpus Luteum / drug effects; Corpus Luteum / metabolism; Cytokines / genetics; Estrous Cycle / genetics; Estrous Cycle / metabolism; Female; Gene Expression Regulation; Lipopolysaccharides / pharmacology; Luteolysis / genetics; Pregnancy; Pregnancy, Animal / genetics; Pregnancy, Animal / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Toll-Like Receptors / genetics; Toll-Like Receptors / metabolism
TL;DR: Based on data, one or more of the TLRs found within the CL may play a role in luteolysis, perhaps via pro-inflammatory cytokine mRNA expression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Differences in mRNA populations of short and long bovine conceptuses on Day 15 of gestation

MOLECULAR REPRODUCTION AND DEVELOPMENT, 83(5), 424–441.

By: C. Barnwell n, P. Farin n, C. Ashwell n, W. Farmer n, S. Galphin n & C. Farin n

MeSH headings : Animals; Cattle; Female; Gestational Age; Morula / cytology; Morula / metabolism; Pregnancy; RNA, Messenger / metabolism
TL;DR: Differences in gene expression were identified between conceptuses recovered on Day 15 of gestation, based on their length, which may be used to identify genes and cellular pathways involved in enhanced conceptus elongation that could serve as markers of successful pregnancy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Maternal serum progesterone concentration and early conceptus development of bovine embryos produced in vivo or in vitro

DOMESTIC ANIMAL ENDOCRINOLOGY, 52, 75–81.

By: C. Barnwell n, P. Farin n, C. Whisnant n, J. Alexander n & C. Farin n

author keywords: Cattle; Embryo; Conceptus; Progesterone; In vitro production; Embryo transfer
MeSH headings : Animals; Blastocyst / physiology; Cattle / embryology; Embryo Transfer / veterinary; Embryonic Development / physiology; Female; Fertilization in Vitro / veterinary; Gestational Age; Male; Pregnancy; Progesterone / blood; Superovulation
TL;DR: Differences in autonomy may exist between in vitro- and in vivo-produced embryos during the period of conceptus elongation with in vitro/in vivo- produced embryos relying more on intrinsic factors to influence elongation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Pregnancy rates of lactating cows after transfer of in vitro produced embryos using X-sorted sperm

Theriogenology, 79(3), 453–461.

By: S. Rasmussen, J. Block, G. Seidel, Z. Brink, K. McSweeney, P. Farin, L. Bonilla, P. Hansen

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Expression of messenger RNAs for insulin-like growth factors and their receptors in bovine fetuses at early gestation from embryos produced in vivo or in vitro

THERIOGENOLOGY, 74(7), 1288–1295.

By: C. Farin n, J. Alexander n & P. Farin n

author keywords: Embryo; In vitro production; Abnormal Offspring Syndrome; Gene expression; IGF
MeSH headings : Animals; Cattle; Female; Fertilization in Vitro / veterinary; Fetus / metabolism; Gene Expression Regulation, Developmental / physiology; Liver / metabolism; Male; Muscle, Skeletal / metabolism; Pregnancy; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptor, IGF Type 1 / genetics; Receptor, IGF Type 1 / metabolism; Receptor, IGF Type 2 / genetics; Receptor, IGF Type 2 / metabolism; Somatomedins / genetics; Somatomedins / metabolism
TL;DR: In conclusion, in vitro embryo culture was associated with subtle changes in fetal development as well as altered expression of both imprinted and non-imprinted genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 article

Pregnancy recognition and abnormal offspring syndrome in cattle

REPRODUCTION FERTILITY AND DEVELOPMENT, Vol. 22, pp. 75–87.

By: C. Farin n, W. Farmer n & P. Farin n

author keywords: AIRN; embryo; fetus; in vitro production; insulin-like growth factor receptor 2
MeSH headings : Animals; Cattle / physiology; Congenital Abnormalities / genetics; Congenital Abnormalities / veterinary; Embryonic Development / genetics; Embryonic Development / physiology; Female; Insulin-Like Growth Factor II / genetics; Insulin-Like Growth Factor II / physiology; Pregnancy; Pregnancy, Animal / genetics; Pregnancy, Animal / physiology; RNA, Antisense / genetics; RNA, Antisense / physiology; Receptors, Somatomedin / genetics; Receptors, Somatomedin / physiology; Syndrome; Uterus / physiology
TL;DR: The present review addresses the development of the post-hatching bovine conceptus, its interactions with the maternal system and changes in development that can occur as a result of in vivo and in vitro manipulations of the bovines embryo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 article

SUBCUTANEOUS ADMINISTRATION OF FOLLICLE STIMULATING HORMONE FOR SUPEROVULATION OF HOLSTEIN COWS

REPRODUCTION FERTILITY AND DEVELOPMENT, Vol. 21, pp. 243–244.

By: P. Farin n, K. Dowdall n, J. Hicks n, C. Farin n & C. Whisnant n

TL;DR: Administration of FSH using 3 SC injections in combination with a progesterone-releasing device was an effective method for superovulation of Holstein cows and there was no effect of route of F SH administration on the concentrations of serum FSH at any time point. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 article

Errors in development of fetuses and placentas from in vitro-produced bovine embryos

Farin, P. W., Piedrahita, J. A., & Farin, C. E. (2006, January 7). THERIOGENOLOGY, Vol. 65, pp. 178–191.

By: P. Farin n, J. Piedrahita n & C. Farin n

author keywords: bovine; embryo culture; nuclear transfer; fetus; placenta
MeSH headings : Animals; Breeding / methods; Cattle / embryology; Embryo Culture Techniques / methods; Embryo Culture Techniques / veterinary; Embryo Transfer / veterinary; Embryonic Development; Female; Fertilization in Vitro / veterinary; Gene Expression Regulation, Developmental; Male; Nuclear Transfer Techniques; Phenotype; Placenta / blood supply; Placenta / physiology; Placentation; Pregnancy; Pregnancy Complications / epidemiology; Pregnancy Complications / veterinary; Pregnancy Outcome / veterinary
TL;DR: The term 'abnormal offspring syndrome (AOS)' is introduced and a classification system of developmental outcomes is proposed to facilitate research efforts on the mechanisms of the various abnormal phenotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Effects of embryo culture on angiogenesis and morphometry of bovine placentas during early gestation

BIOLOGY OF REPRODUCTION, 73(4), 663–671.

By: . Miles n, C. Farin n, K. Rodriguez n, J. Alexander n & P. Farin n

author keywords: developmental biology; embryo; gene regulation; in vitro fertilization; placenta
MeSH headings : Animals; Blastocyst / physiology; Blood Vessels / anatomy & histology; Cattle; Coculture Techniques; Culture Media / pharmacology; Culture Media, Serum-Free / pharmacology; Embryo Culture Techniques; Embryo, Mammalian / anatomy & histology; Female; Fertilization in Vitro / methods; Gene Expression; Gene Expression Regulation, Developmental; Gestational Age; Neovascularization, Physiologic; PPAR gamma / genetics; PPAR gamma / metabolism; Placenta / anatomy & histology; Placenta / blood supply; Placenta / drug effects; Pregnancy; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
TL;DR: Placentas from embryos produced in vitro using a semidefined culture system exhibited a greater degree of aberrant development of the placenta during early gestation than with placentas produced in vivo or in vivo using an undefined culture system. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Angiogenesis and morphometry of bovine placentas in late gestation from embryos produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 71(6), 1919–1926.

By: . Miles n, C. Farin n, K. Rodriguez n, J. Alexander n & P. Farin n

author keywords: developmental biology; embryo; gene regulation; in vitro fertilization; placenta
MeSH headings : Animals; Blood Vessels / anatomy & histology; Cattle; Chorionic Villi / anatomy & histology; Female; Fetal Weight; Gestational Age; Neovascularization, Physiologic; PPAR gamma / genetics; PPAR gamma / metabolism; Placenta / anatomy & histology; Placenta / blood supply; Pregnancy; RNA, Messenger / metabolism; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
TL;DR: Findings are consistent with the concept that compensatory mechanisms exist in the vascular beds of placentas from bovine embryos produced in vitro. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Epigenetic and genomic imprinting analysis in nuclear transfer derived Bos gaurus/Bos taurus hybrid fetuses

Biology of Reproduction, 71(2), 470–478.

By: S. Dindot n, P. Farin n, C. Farin n, J. Romano*, S. Walker*, C. Long, J. Piedrahita n

MeSH headings : Animals; Cattle; Chimera / genetics; Cloning, Organism; DNA Methylation; DNA, Satellite; Embryonic Development; Epidermis / physiology; Epigenesis, Genetic / genetics; Exons; Female; Fibroblasts / physiology; Genomic Imprinting / genetics; Genotype; Insulin-Like Growth Factor II / genetics; Keratins / genetics; Nuclear Transfer Techniques; Placenta; Pregnancy; Promoter Regions, Genetic; Proteins / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics
TL;DR: The use of a bovine interspecies model for the assessment and characterization of epigenetic modifications and genomic imprinting in Day 40-old female NT-derived fetuses and placenta indicates that the nuclear transfer process affects gene expression patterns in the trophectoderm- and inner cell mass-derived tissues to different extents. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2004 journal article

Pregnancy loss associated with embryo technologies in cattle

Medecin Veterinaire Du Quebec, 34(1), 62.

By: P. Farin, J. Miles & C. Farin

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Development of skeletal muscle and expression of candidate genes in bovine fetuses from embryos produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 67(2), 401–408.

By: A. Crosier n, C. Farin n, K. Rodriguez n, P. Blondin n, J. Alexander n & P. Farin n

author keywords: conceptus; developmental biology; embryo; fetus; gene regulation; in vitro fertilization
MeSH headings : Animals; Blastocyst / physiology; Body Weight / physiology; Cattle; DNA Primers; Electrophoresis, Agar Gel; Embryo Transfer; Embryonic and Fetal Development / physiology; Female; Fertilization in Vitro; Fetus / metabolism; Gene Expression Regulation, Developmental / genetics; Glyceraldehyde-3-Phosphate Dehydrogenases / metabolism; In Vitro Techniques; Indicators and Reagents; Male; Muscle Fibers, Skeletal / physiology; Muscle Proteins / biosynthesis; Muscle Proteins / genetics; Muscle, Skeletal / anatomy & histology; Muscle, Skeletal / embryology; Pregnancy; RNA / biosynthesis; RNA / genetics; Reverse Transcriptase Polymerase Chain Reaction
TL;DR: In vitro production of embryos resulted in fetuses with altered development of skeletal muscle fibers, and myostatin was identified as the candidate gene whose expression may contribute to the observed changes in muscle development of these fetuses. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 article

Influence of in vitro systems on embryo survival and fetal development in cattle

Farin, P. W., Crosier, A. E., & Farin, C. E. (2001, January 1). THERIOGENOLOGY, Vol. 55, pp. 151–170.

By: P. Farin n, A. Crosier n & C. Farin n

author keywords: bovine; embryo; fetus; in vitro production; gene expression; large offspring syndrome
MeSH headings : Animals; Cattle / embryology; Culture Techniques; Embryo Transfer / veterinary; Embryo, Mammalian / physiology; Embryo, Mammalian / ultrastructure; Embryonic and Fetal Development; Female; Fertilization in Vitro / veterinary; Pregnancy
TL;DR: Findings indicate that exposure to some in vitro environments during the first 7 days of life can profoundly influence fetal and placental development in cattle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Ovarian follicular development following administration of progesterone or aspiration of ovarian follicles in Holstein cows

THERIOGENOLOGY, 55(3), 805–821.

By: J. Cavalieri*, P. Farin*, J. Kinder, S. Van Camp*, M. Whitacre*, S. Washburn*, J. Britt*

author keywords: ovarian follicle aspiration; FSH; progesterone; synchronization; ultrasonography
MeSH headings : Animals; Biopsy, Needle / veterinary; Cattle / physiology; Dinoprost / pharmacology; Estradiol / blood; Estrus; Estrus Synchronization / blood; Female; Follicle Stimulating Hormone / blood; Ovarian Follicle / drug effects; Ovarian Follicle / growth & development; Ovary / diagnostic imaging; Ovulation; Progesterone / pharmacology; Ultrasonography
TL;DR: Both the administration of P4 and the aspiration of follicle aspiration on Day 7 of the estrous cycle improves the synchrony of ovulation when luteolysis is induced on Day 11 and results in similar concentrations of FSH at the time of follicular wave emergence, but the timing of wave emergence and the number of follicles post-emergence differ. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

Ultrastructural morphometry of bovine blastocysts produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 64(5), 1375–1385.

By: A. Crosier n, P. Farin n, M. Dykstra n, J. Alexander n & C. Farin n

author keywords: early development; IVF/ART
MeSH headings : Animals; Apoptosis; Blastocyst / ultrastructure; Blastomeres / ultrastructure; Cattle / embryology; Cell Nucleus / ultrastructure; Culture Media; Culture Techniques; Cytoplasm / ultrastructure; Fertilization in Vitro / veterinary; Microscopy, Electron; Mitochondria / ultrastructure; Superovulation; Vacuoles / ultrastructure
TL;DR: Blastocysts produced in vitro possessed deviations in volume densities of organelles associated with cellular metabolism as well as deviations associated with altered embryonic differentiation, however, the specific nature of these deviations varied with the type of culture conditions used for in vitro embryo production. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

In vitro production of embryos alters levels of insulin-like growth factor-II messenger ribonucleic acid in bovine fetuses 63 days after transfer

BIOLOGY OF REPRODUCTION, 62(2), 384–389.

By: P. Blondin n, P. Farin n, A. Crosier n, J. Alexander n & C. Farin n

MeSH headings : Animals; Cattle; Embryo Transfer; Embryo, Mammalian / metabolism; Female; Fertilization in Vitro; Fetus / metabolism; Gestational Age; In Vitro Techniques; Insulin-Like Growth Factor II / biosynthesis; Liver / metabolism; Muscle, Skeletal / metabolism; Pregnancy; RNA, Messenger / biosynthesis; RNA, Ribosomal / biosynthesis; Ribonucleases / analysis
TL;DR: Fetuses originating from in vitro production systems possessed altered levels of IGF-II mRNA in both liver and skeletal muscle at Day 70 of gestation, according to the objective of this study. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Ultrastructural morphometry of bovine compact morulae produced in vivo or in vitro

BIOLOGY OF REPRODUCTION, 62(5), 1459–1465.

By: A. Crosier n, P. Farin n, M. Dykstra n, J. Alexander n & C. Farin n

MeSH headings : Animals; Cattle; Cell Culture Techniques / methods; Cytoplasm; Female; Fertilization in Vitro; Morula / cytology; Morula / ultrastructure
TL;DR: Compound morulae produced in IVPS culture medium possessed the greatest deviations in cellular ultrastructure, compared with those produced in vivo. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Birth of a Holstein freemartin calf co-twinned to a schistosomus reflexus fetus

THERIOGENOLOGY, 52(5), 815–826.

By: J. Cavalieri n & P. Farin n

author keywords: freemartinism; schistosomus reflexus; cytogenetic testing; hCG
MeSH headings : Abdomen / abnormalities; Animals; Cattle; Cattle Diseases / pathology; Cells, Cultured; Chorionic Gonadotropin; Congenital Abnormalities / pathology; Congenital Abnormalities / veterinary; Estradiol / blood; Female; Freemartinism / blood; Freemartinism / diagnosis; Freemartinism / pathology; Lymphocytes / pathology; Male; Progesterone / blood; Testosterone / blood; Twins; Y Chromosome
TL;DR: It is documents that the freemartin condition can be induced by a male fetus with severe developmental abnormalities, and the hypothesis that masculinization of the freEMartin reproductive tract arises from diffusion of androgen and possibly other substances from the male co-twin rather than from endogenous production of androgens within the freamartin. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Does in vitro culture affect the expression of insulin-like growth factor-II (IGF-II) messenger RNA in fetal bovine liver?

Biology of Reproduction, 60(1999), 248–249.

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Estimates of pregnancy outcomes based on selection of bovine embryos produced in vivo or in vitro

THERIOGENOLOGY, 52(4), 659–670.

By: P. Farin n, B. Slenning n & J. Britt n

author keywords: cattle; embryo quality; evaluators; pregnancy rates; model
MeSH headings : Animals; Cattle; Embryo Transfer / veterinary; Embryonic and Fetal Development; Female; Fertilization in Vitro / veterinary; Pregnancy; Pregnancy Outcome / veterinary; Probability; Video Recording
TL;DR: There was substantial variation among evaluators in the proportion of recipients becoming pregnant, especially for embryos produced in vitro, and the number of embryo transfers required per pregnancy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1995 journal article

AGREEMENT AMONG EVALUATORS OF BOVINE EMBRYOS PRODUCED IN-VIVO OR IN-VITRO

THERIOGENOLOGY, 44(3), 339–349.

By: P. Farin n, J. Britt n, D. Shaw n & B. Slenning n

author keywords: CATTLE; EMBRYO MORPHOLOGY; EMBRYO GRADING; AGREEMENT; KAPPA
TL;DR: It is suggested that good to excellent agreement exists for classifying Day 7 bovine embryos by stage and by extremes of quality grade (Grades 1 and 4) but not by degree of abnormal morphology (grades 2 and 3). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1995 journal article

TRANSFER OF BOVINE EMBRYOS PRODUCED IN-VIVO OR IN-VITRO - SURVIVAL AND FETAL DEVELOPMENT

BIOLOGY OF REPRODUCTION, 52(3), 676–682.

By: P. Farin n & C. Farin n

MeSH headings : Animals; Body Weight / physiology; Cattle; Embryo Transfer; Embryonic and Fetal Development / physiology; Female; Fertilization in Vitro; Fetal Viability; Pregnancy; Progesterone / blood
TL;DR: Comparing survival after transfer of bovine embryos produced in vivo with those produced in vitro and to examine the physical characteristics of fetuses produced from these transfers found fetuses from embryosproduced in vivo were heavier and had skeletal measurements that were disproportionate to body weight. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1994 journal article

Effects of calving season and milk yield on pregnancy risk and income in North Carolina Holstein cows

Journal of Dairy Science, 77(7), 1848.

By: P. Farin*, B. Slenning, M. Correa & J. Brit

MeSH headings : Animal Feed / economics; Animals; Breeding; Cattle / physiology; Dairying / economics; Female; Income; Lactation / physiology; North Carolina; Pregnancy; Pregnancy, Animal / physiology; Seasons; Time Factors
TL;DR: Effects of season of calving and milk yield and their potential interaction on days from calving to last breeding were investigated using survival analysis and an economic model in 2000 Holstein cows that calved during 1989 and 1990, suggesting that these factors may act independently to affect reproduction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

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