Works (3)
Updated: July 5th, 2023 15:54
2010 journal article
A Five-Step Synthesis of (S)-Macrostomine from (S)-Nicotine
ORGANIC LETTERS, 12(20), 4513–4515.
MeSH headings : Isoquinolines / chemical synthesis; Molecular Structure; Nicotine / chemistry
TL;DR:
A concise synthesis of (S)-macrostomine has been accomplished in five steps from natural nicotine in 19% overall yield via a pyridyne Diels-Alder cycloaddition reaction as the key step.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Synthesis of Fused-Ring Nicotine Derivatives from (S)-Nicotine
JOURNAL OF ORGANIC CHEMISTRY, 75(5), 1706–1716.
MeSH headings : Bridged Bicyclo Compounds, Heterocyclic / chemical synthesis; Bridged Bicyclo Compounds, Heterocyclic / chemistry; Cyclization; Dioxins / chemical synthesis; Dioxins / chemistry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nicotine / chemical synthesis; Nicotine / chemistry; Stereoisomerism
TL;DR:
The synthesis of novel fused-ring bicyclic and tricyclic nicotine derivatives from natural (S)-nicotine are described and attempts to synthesize furonicotines resulted in formation of the furonicotine dimers 42 and 49.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Synthesis and regioselective substitution of C-6 alkoxy derivatives of (S)-nicotine
TETRAHEDRON LETTERS, 49(3), 569–572.
author keywords: (S)-nicotine; alkoxynicotine; lithiation; regioselective deprotonation
TL;DR:
Enantiopure (S)-6-alkoxynicotine derivatives have been synthesized in two steps from (S-nicotine via (S)"6-iodonicotine", using mesityllithium as the base at 0 °C fordeprotonation and substitution at the C-5 position of the pyridine ring of (S)+6-methoxynICotine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018