Works (38)

Updated: July 20th, 2023 21:13

2022 journal article

Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy

NATIONAL SCIENCE REVIEW, 9(3).

By: H. Li*, Z. Wang*, E. Archibong*, Q. Wu*, G. Chen*, Q. Hu n, T. Ci*, Z. Chen* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; CAR T therapy; microneedle patch; solid tumor treatment; cell delivery
Source: Web Of Science
Added: March 28, 2022

2021 article

Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets

Hu, Q., Li, H., Archibong, E., Chen, Q., Ruan, H., Ahn, S., … Gu, Z. (2021, April 26). NATURE BIOMEDICAL ENGINEERING.

By: Q. Hu n, H. Li*, E. Archibong n, Q. Chen n, H. Ruan*, S. Ahn*, E. Dukhovlinova*, Y. Kang* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antibodies, Monoclonal, Humanized; Blood Platelets; Cell-Derived Microparticles; Hydrogels; Immunotherapy, Adoptive; Mice; Neoplasm Recurrence, Local / prevention & control; T-Lymphocytes; Tumor Microenvironment
Source: Web Of Science
Added: June 10, 2021

2020 journal article

CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation

SCIENCE ADVANCES, 6(21).

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; Cholesterol; DNA / genetics; DNA / metabolism; Gene Editing; Polymers / metabolism; Proprotein Convertase 9 / genetics; Proprotein Convertase 9 / metabolism; RNA / genetics; Ribonucleoproteins / genetics
Source: Web Of Science
Added: June 22, 2020

2019 journal article

A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade

ADVANCED MATERIALS, 31(17).

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: bioresponsive materials; drug delivery; epigenetic modulation; immune checkpoint blockade; immunotherapy
MeSH headings : Animals; Antibodies, Monoclonal / pharmacology; Antibodies, Monoclonal, Humanized; Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / pharmacology; Calcium Carbonate / chemistry; Cell Line, Tumor; Cytidine / analogs & derivatives; Cytidine / pharmacology; Drug Delivery Systems / methods; Drug Liberation; Drug Therapy, Combination / methods; Humans; Hydrogen-Ion Concentration; Immunosuppressive Agents / chemistry; Immunosuppressive Agents / pharmacology; Immunotherapy / methods; Melanoma / drug therapy; Nanoparticles / chemistry; Programmed Cell Death 1 Receptor / metabolism; Reactive Oxygen Species / metabolism; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: May 13, 2019

2019 journal article

A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

ACS NANO, 13(4), 4354–4360.

By: G. Yang n, Q. Chen n, D. Wen n, Z. Chen n, J. Wang n, G. Chen n, Z. Wang*, X. Zhang n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; microneedle; exosome; keratin; hair regrowth; transdermal drug delivery
MeSH headings : Animals; Cell Line; Delayed-Action Preparations / chemistry; Drug Delivery Systems / instrumentation; Equipment Design; Hair / chemistry; Hair / drug effects; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / growth & development; Humans; Injections, Subcutaneous; Keratins / chemistry; Mice, Inbred C57BL; Transdermal Patch
Source: Web Of Science
Added: June 4, 2019

2019 journal article

Adipocytes as Anticancer Drug Delivery Depot

MATTER, 1(5), 1203–1214.

By: D. Wen n, J. Wang n, G. Van Den Driessche n, Q. Chen n, Y. Zhang n, G. Chen n, H. Li*, J. Soto* ...

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: April 6, 2020

2019 journal article

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

NATURE NANOTECHNOLOGY, 14(1), 89-+.

By: Q. Chen n, C. Wang n, X. Zhang*, G. Chen*, Q. Hu n, H. Li*, J. Wang n, D. Wen* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Biocompatible Materials / chemistry; Calcium Carbonate / chemistry; Female; Fibrin / chemistry; Gels / chemistry; Humans; Immunity; Immunotherapy / methods; Luminescent Measurements; Melanoma, Experimental / pathology; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neoplasm Recurrence, Local / pathology; Neoplasms / pathology; Neoplasms / surgery; Phagocytosis
Source: Web Of Science
Added: January 21, 2019

2019 journal article

Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells

ADVANCED MATERIALS, 31(23).

By: Q. Chen n, Q. Hu n, E. Dukhovlinova*, G. Chen*, S. Ahn*, C. Wang n, E. Ogunnaike n, F. Ligler n, G. Dotti*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: CAR T cells; cell therapy; drug delivery; immunotherapy; photothermal therapy
MeSH headings : Animals; Antigens / metabolism; Cell Line, Tumor; Chondroitin Sulfate Proteoglycans / metabolism; Combined Modality Therapy; Female; Heterografts; Humans; Hyperthermia, Induced; Immunotherapy, Adoptive / methods; Indocyanine Green / chemistry; Melanoma / pathology; Melanoma / therapy; Membrane Proteins / metabolism; Mice, SCID; Nanoparticles / chemistry; Photosensitizing Agents / chemistry; Phototherapy / methods; Polylactic Acid-Polyglycolic Acid Copolymer / chemistry; Proteoglycans / metabolism; Skin Neoplasms / pathology; Skin Neoplasms / therapy; T-Lymphocytes / metabolism; T-Lymphocytes / transplantation; Tumor Microenvironment
Source: Web Of Science
Added: July 22, 2019

2019 journal article

Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy

NANO RESEARCH, 12(6), 1313–1320.

By: J. Yan n, X. Zhang n, Y. Liu n, Y. Ye n, J. Yu n, Q. Chen n, J. Wang n, Y. Zhang n ...

co-author countries: United States of America 🇺🇸
author keywords: liquid metal; melanin nanoparticles; nanomedicine; shape-controlled synthesis; photothermal therapy
Source: Web Of Science
Added: June 17, 2019

2018 journal article

Advances in transformable drug delivery systems

BIOMATERIALS, 178, 546–558.

By: Q. Hu n, Q. Chen n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: Drug delivery; Stimuli-responsive; Cancer therapy; Transformable formulation
MeSH headings : Animals; Drug Delivery Systems / methods; Extracellular Space / chemistry; Humans; Intracellular Space / chemistry; Microbubbles; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neoplasms / diagnosis; Neoplasms / pathology
Source: Web Of Science
Added: October 19, 2018

2018 journal article

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy

NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840.

By: Q. Hu n, W. Sun*, J. Wang n, H. Ruan n, X. Zhang*, Y. Ye n, S. Shen*, C. Wang n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antibodies / chemistry; Antibodies / immunology; Blood Platelets / chemistry; Blood Platelets / cytology; Blood Platelets / metabolism; Cell Line, Tumor; Chemokines / metabolism; Cytokines / metabolism; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells / chemistry; Hematopoietic Stem Cells / cytology; Hematopoietic Stem Cells / metabolism; Leukemia / therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor / deficiency; Programmed Cell Death 1 Receptor / genetics; Programmed Cell Death 1 Receptor / immunology; T-Lymphocytes / cytology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
Source: Web Of Science
Added: November 26, 2018

2018 journal article

Delivery Strategies for Immune Checkpoint Blockade

ADVANCED HEALTHCARE MATERIALS, 7(20).

By: Q. Chen n, C. Wang n, G. Chen n, Q. Hu n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: biomaterials; cancer therapy; drug delivery; immune checkpoint blockade; immunotherapy
MeSH headings : Autoimmune Diseases / immunology; Autoimmune Diseases / therapy; Humans; Immunotherapy / methods; Neoplasms / immunology; Neoplasms / therapy
Source: Web Of Science
Added: November 19, 2018

2018 journal article

Engineering PD-1-Presenting Platelets for Cancer Immunotherapy

NANO LETTERS, 18(9), 5716–5725.

By: X. Zhang n, J. Wang n, Z. Chen n, Q. Hu n, C. Wang n, J. Yan n, G. Dotti*, P. Huang*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Drug delivery; platelet; immune checkpoint blockade; immunotherapy; nanomedicine
Source: Web Of Science
Added: October 16, 2018

2018 journal article

In situ formed reactive oxygen species-responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

SCIENCE TRANSLATIONAL MEDICINE, 10(429).

By: C. Wang n, J. Wang n, X. Zhang n, S. Yu n, D. Wen n, Q. Hu n, Y. Ye n, H. Bomba n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Cell Line, Tumor; Combined Modality Therapy; Deoxycytidine / analogs & derivatives; Deoxycytidine / therapeutic use; Female; Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry; Immunotherapy / methods; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor / metabolism; Gemcitabine
Source: Web Of Science
Added: August 6, 2018

2018 review

Leveraging Engineering of Cells for Drug Delivery

[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 51(3), 668–677.

By: Z. Chen n, Q. Hu n & Z. Gu n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cell Engineering; Drug Delivery Systems; Humans
Source: Web Of Science
Added: August 6, 2018

2018 journal article

PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy

ADVANCED MATERIALS, 30(22).

By: X. Zhang n, C. Wang n, J. Wang n, Q. Hu n, B. Langworthy*, Y. Ye n, W. Sun n, J. Lin* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: cancer immunotherapy; cell therapy; drug delivery; immune checkpoint blockade; nanomedicine
MeSH headings : Humans; Immunotherapy; Lymphocytes, Tumor-Infiltrating; Neoplasms / therapy; Programmed Cell Death 1 Receptor; T-Lymphocytes; Tumor Microenvironment
Source: Web Of Science
Added: August 6, 2018

2017 journal article

A melanin-mediated cancer immunotherapy patch

SCIENCE IMMUNOLOGY, 2(17).

By: Y. Ye n, C. Wang n, X. Zhang n, Q. Hu n, Y. Zhang n, Q. Liu n, D. Wen n, J. Milligan n ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cancer Vaccines / immunology; Cancer Vaccines / metabolism; Cell Line, Tumor; Dendritic Cells / immunology; Dendritic Cells / metabolism; Female; Immunotherapy / instrumentation; Immunotherapy / methods; Infrared Rays; Kaplan-Meier Estimate; Melanins / immunology; Melanins / metabolism; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Needles; Neoplasms, Experimental / immunology; Neoplasms, Experimental / pathology; Neoplasms, Experimental / therapy; Transdermal Patch; Tumor Burden / immunology
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Anaerobe-Inspired Anticancer Nanovesicles

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(10), 2588–2593.

By: C. Qian n, P. Feng*, J. Yu n, Y. Chen*, Q. Hu n, W. Sun n, X. Xiao*, X. Hu n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; nanomedicines; photodynamic therapy
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Death / drug effects; Cell Proliferation / drug effects; Clostridium / chemistry; Clostridium / metabolism; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Hypoxia / metabolism; Imidazoles / chemistry; Imidazoles / pharmacology; Nanoparticles / chemistry; Prodrugs / chemistry; Prodrugs / pharmacology; Salmonella / chemistry; Salmonella / metabolism; Tirapazamine / chemistry; Tirapazamine / pharmacology
Source: Web Of Science
Added: August 6, 2018

2017 review

Conjugated polymer nanomaterials for theranostics

[Review of ]. ACTA PHARMACOLOGICA SINICA, 38(6), 764–781.

By: Q. Cheng-gen n, Y. Chen*, P. Feng*, X. Xiao*, M. Dong*, J. Yu n, Q. Hu n, Q. Shen*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: conjugated polymer; theranostics; biomedical imaging; photodynamic therapy; photothermal therapy; stimuli; responsive drug delivery
MeSH headings : Drug Delivery Systems; Nanostructures / chemistry; Photochemotherapy; Polymers / chemistry; Theranostic Nanomedicine
Source: Web Of Science
Added: August 6, 2018

2017 review

Engineering platelet-mimicking drug delivery vehicles

[Review of ]. FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING, 11(4), 624–632.

By: Q. Hu n, H. Bomba n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: drug delivery; platelets; nanomedicine; bio-inspired; biomimetic
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Enhanced Endosomal Escape by Light-Fueled Liquid-Metal Transformer

NANO LETTERS, 17(4), 2138–2145.

By: Y. Lu n, Y. Lin n, Z. Chen n, Q. Hu n, Y. Liu n, S. Yu n, W. Gao n, M. Dickey n, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Drug delivery; liquid metal; stimuli-responsive; morphological transformation; endosomal escape
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy

ADVANCED MATERIALS, 29(13).

By: Q. Hu n, W. Sun n, C. Qian n, H. Bomba n, H. Xin n & Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Biomimetic Materials / chemistry; Blood Vessels / drug effects; Blood Vessels / metabolism; Cell Line, Tumor; Cell Survival / drug effects; Cells, Cultured; Dextrans / chemistry; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells / drug effects; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Mice, Nude; Microtubules / enzymology; Microtubules / metabolism; Nanostructures / chemistry; Neoplasm Transplantation; Neoplasms / blood supply; Neoplasms / drug therapy; Neoplasms / metabolism; Oligopeptides / chemistry; Paclitaxel / administration & dosage; Paclitaxel / pharmacokinetics; Tumor Necrosis Factor-alpha / chemistry; Tumor Necrosis Factor-alpha / pharmacokinetics
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook

ADVANCED MATERIALS, 29(29).

By: C. Wang n, Y. Ye n, Q. Hu n, A. Bellotti n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: biomaterials; cancer immunotherapy; cell therapy; drug delivery
MeSH headings : Animals; Antigen-Presenting Cells / cytology; Antigen-Presenting Cells / metabolism; Antigens / genetics; Antigens / immunology; Antigens / metabolism; Biocompatible Materials / chemistry; Cell- and Tissue-Based Therapy; Humans; Immunologic Factors / metabolism; Immunologic Factors / therapeutic use; Immunotherapy; Nanostructures / chemistry; Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018

2016 journal article

ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging

THERANOSTICS, 6(7), 1053–1064.

By: C. Qian*, Y. Chen, S. Zhu, J. Yu*, L. Zhang, P. Feng, X. Tang, Q. Hu* ...

author keywords: drug delivery; nanomedicine; stimuli-responsive; ATP-responsive; theranostics; conjugated polymers
MeSH headings : Adenosine Triphosphate / metabolism; Antineoplastic Agents / administration & dosage; Boronic Acids / metabolism; Doxorubicin / administration & dosage; Drug Carriers / administration & dosage; Hep G2 Cells; Humans; Liver Neoplasms / diagnostic imaging; Liver Neoplasms / drug therapy; Nanoparticles / administration & dosage; Optical Imaging / methods; Theranostic Nanomedicine / methods
Source: Web Of Science
Added: August 6, 2018

2016 conference paper

Cell membrane-mediated anticancer drug delivery

Nanotechnology: delivering on the promise, vol 2, 1224, 197–211.

By: Q. Hu & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Dual targeted nanocarrier for brain ischemic stroke treatment

JOURNAL OF CONTROLLED RELEASE, 233, 64–71.

By: Y. Zhao*, Y. Jiang*, W. Lv*, Z. Wang*, L. Lv*, B. Wang*, X. Liu*, Y. Liu* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Stroke; Stroke homing peptide; Dual-targeting liposomes; ZL006; Neuroprotection
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

ADVANCED MATERIALS, 28(43), 9573-+.

By: Q. Hu n, C. Qian n, W. Sun n, J. Wang n, Z. Chen n, H. Bomba n, H. Xin n, Q. Shen*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / pharmacokinetics; Biomimetics; Blood Platelets / cytology; Bone and Bones / metabolism; Cell Line, Tumor; Cell Membrane / metabolism; Cellular Microenvironment; Disease Models, Animal; Drug Carriers / chemistry; Drug Carriers / pharmacokinetics; Humans; Mice; Multiple Myeloma / complications; Multiple Myeloma / drug therapy; Multiple Myeloma / metabolism; Multiple Myeloma / pathology; Nanoparticles / chemistry; Thrombosis / complications; Thrombosis / drug therapy
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Enhanced Antiglioblastoma Efficacy of Neovasculature and Glioma Cells Dual Targeted Nanoparticles

MOLECULAR PHARMACEUTICS, 13(10), 3506–3517.

By: L. Lv*, Y. Jiang*, X. Liu*, B. Wang*, W. Lv*, Y. Zhao*, H. Shi*, Q. Hu n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: glioma; antineovasculature; dual-targeted nanoparticle; drug delivery; paclitaxel
MeSH headings : Animals; Antineoplastic Agents, Phytogenic / chemistry; Antineoplastic Agents, Phytogenic / therapeutic use; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma / drug therapy; Glioma / drug therapy; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles / chemistry; Paclitaxel / chemistry; Paclitaxel / therapeutic use; Polyesters / chemistry; Polyethylene Glycols / chemistry; Rats
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy

ADVANCED MATERIALS, 28(17), 3313–3320.

By: C. Qian n, J. Yu n, Y. Chen*, Q. Hu n, X. Xiao*, W. Sun n, C. Wang n, P. Feng*, Q. Shen*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Cell Hypoxia; Cell Survival / drug effects; Doxorubicin / chemistry; Doxorubicin / pharmacology; Doxorubicin / therapeutic use; Drug Carriers / chemistry; HeLa Cells; Humans; Hydrogen-Ion Concentration; Light; Mice; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles / chemistry; Neoplasms / diagnostic imaging; Neoplasms / drug therapy; Neoplasms / pathology; Optical Imaging; Polyvinyl Alcohol / chemistry; Singlet Oxygen / chemistry; Singlet Oxygen / metabolism; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration

ACS NANO, 10(1), 1292–1299.

By: D. Shi*, X. Xu*, Y. Ye n, K. Song*, Y. Cheng, J. Di n, Q. Hu n, J. Li ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; tissue engineering; hydrogel; regenerative medicine; nanoparticles
Source: Web Of Science
Added: August 6, 2018

2016 review

Recent advances of cocktail chemotherapy by combination drug delivery systems

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 98, 19–34.

By: Q. Hu n, W. Sun n, C. Wang n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: Chemotherapy; Combination; Cancer; Nanocarriers; Drug delivery
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Drug Delivery Systems; Humans; Nanoparticles / administration & dosage; Nanoparticles / therapeutic use; Neoplasms / drug therapy
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine

BIOMATERIALS, 96, 1–10.

By: W. Sun n, W. Ji n, Q. Hu n, J. Yu n, C. Wang n, C. Qian n, G. Hochu n, Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: Cancer; Protein delivery; DNA structures; Cytokine; Nanomedicine
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots

NANO LETTERS, 16(2), 1118–1126.

By: Q. Hu n, W. Sun n, Y. Lu n, H. Bomba n, Y. Ye n, T. Jiang*, A. Isaacson*, Z. Gu n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Drug delivery; stimuli-responsive; tumor microenvironment; apoptosis; antiangiogenesis
MeSH headings : Angiogenesis Inhibitors / administration & dosage; Angiogenesis Inhibitors / chemistry; Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Apoptosis / drug effects; Breast Neoplasms / drug therapy; Breast Neoplasms / genetics; Cell Line, Tumor; Cell Membrane Permeability / drug effects; Drug Delivery Systems; Endosomes / drug effects; Gene Transfer Techniques; Humans; Hyaluronoglucosaminidase / biosynthesis; Hyaluronoglucosaminidase / chemistry; Mice; Snake Venoms / administration & dosage; Snake Venoms / chemistry; TNF-Related Apoptosis-Inducing Ligand / administration & dosage; Tumor Microenvironment / drug effects; Xenograft Model Antitumor Assays
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Anticancer Platelet-Mimicking Nanovehicles

ADVANCED MATERIALS, 27(44), 7043-+.

By: Q. Hu n, W. Sun n, C. Qian n, C. Wang n, H. Bomba n & Z. Gu n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Biomimetic Materials / chemistry; Blood Platelets / cytology; Cell Line, Tumor; Cell Membrane / chemistry; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Humans; Intracellular Space / metabolism; Mice; Nanomedicine / methods; Nanostructures / chemistry; TNF-Related Apoptosis-Inducing Ligand / chemistry; TNF-Related Apoptosis-Inducing Ligand / metabolism
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

Angewandte Chemie International Edition, 54(41), 12029–12033.

By: W. Sun n, W. Ji n, J. Hall n, Q. Hu n, C. Wang n, C. Beisel n, Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR-Cas9; DNA; drug delivery; genome editing; nanoparticles
MeSH headings : Animals; CRISPR-Associated Proteins / administration & dosage; CRISPR-Associated Proteins / chemistry; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Cell Line; Clustered Regularly Interspaced Short Palindromic Repeats; DNA / administration & dosage; DNA / chemistry; DNA / genetics; Green Fluorescent Proteins / genetics; Humans; Mice, Nude; Nanoparticles / chemistry; Neoplasms / genetics; Neoplasms / therapy; RNA, Guide, Kinetoplastida / administration & dosage; RNA, Guide, Kinetoplastida / chemistry; RNA, Guide, Kinetoplastida / genetics; Streptococcus pyogenes / chemistry; Streptococcus pyogenes / genetics
Sources: Web Of Science, Crossref
Added: August 6, 2018

2015 article

Spatiotemporal drug delivery using laser-generated-focused ultrasound system

Di, J., Kim, J., Hu, Q., Jiang, X., & Gu, Z. (2015, December 28). JOURNAL OF CONTROLLED RELEASE, Vol. 220, pp. 592–599.

By: J. Di n, J. Kim n, Q. Hu n, X. Jiang n & Z. Gu n

co-author countries: United States of America 🇺🇸
author keywords: Drug delivery; Photoacoustic; Nanoparticles; Microgels; Stimuli responsive
MeSH headings : Alginates / chemistry; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / chemistry; Cell Proliferation / drug effects; Cell Survival / drug effects; Chemistry, Pharmaceutical; Ciprofloxacin / administration & dosage; Ciprofloxacin / chemistry; Delayed-Action Preparations; Dimethylpolysiloxanes / chemistry; Disk Diffusion Antimicrobial Tests; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers; Equipment Design; Escherichia coli / drug effects; Escherichia coli / growth & development; Gels; Glucuronic Acid / chemistry; HeLa Cells; Hexuronic Acids / chemistry; Humans; Kinetics; Lactic Acid / chemistry; Lasers; Nanoparticles; Photoacoustic Techniques; Polyglycolic Acid / chemistry; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Soot / chemistry; Spheroids, Cellular; Technology, Pharmaceutical / instrumentation; Technology, Pharmaceutical / methods; Transducers; Ultrasonic Waves; Ultrasonics / instrumentation; Ultrasonics / methods
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Transformable liquid-metal nanomedicine

NATURE COMMUNICATIONS, 6(1).

By: Y. Lu n, Q. Hu n, Y. Lin n, D. Pacardo n, C. Wang n, W. Sun n, F. Ligler n, M. Dickey n, Z. Gu*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / chemistry; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Female; Gallium / chemistry; Humans; Indium / chemistry; Metal Nanoparticles / chemistry; Mice; Mice, Inbred BALB C; Nanomedicine / instrumentation; Nanomedicine / methods; Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Enzyme-responsive nanomaterials for controlled drug delivery

NANOSCALE, 6(21), 12273–12286.

By: Q. Hu n, P. Katti* & Z. Gu n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Apoptosis; Biotechnology; Drug Delivery Systems; Enzymes / chemistry; Humans; Inorganic Chemicals / chemistry; Liposomes / chemistry; Metal Nanoparticles / chemistry; Mice; Nanostructures / chemistry; Nanotechnology; Oxidoreductases / chemistry; Peptide Hydrolases / chemistry; Phospholipases / chemistry
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.