1999 journal article

Mapping and expression of a bifunctional thymidylate synthase, dihydrofolate reductase gene from maize


By: K. Cox*, D. Robertson n & R. Fites n

author keywords: bifunctional enzymes; dihydrofolate reductase; DNA synthesis; endoreduplication; maize; thymidylate synthase
MeSH headings : Amino Acid Sequence; Blotting, Northern; Chromosome Mapping; Cloning, Molecular; DNA, Complementary / chemistry; DNA, Complementary / genetics; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Molecular Sequence Data; Multienzyme Complexes / genetics; RNA, Plant / genetics; RNA, Plant / metabolism; Seeds / enzymology; Seeds / genetics; Seeds / growth & development; Sequence Analysis, DNA; Tetrahydrofolate Dehydrogenase / genetics; Thymidylate Synthase / genetics; Tissue Distribution; Zea mays / enzymology; Zea mays / genetics
TL;DR: A bifunctional gene (ZmDHFR-TS) encoding dihydrofolate reductase (DHFR) and thymidylate synthase (TS) was cloned from a Zea mays cDNA library and represents the first DHFR-TCS gene cloning from a monocotyledonous plant. (via Semantic Scholar)
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Added: August 6, 2018

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