Robert Smart
Sohn, A. L., Witherspoon, J. G., Smart, R. C., & Muddiman, D. C. (2025). Three-dimensional mass spectrometry imaging (3D MSI): incorporating top-hat IR-MALDESI and automatic z-axis correction. Analytical and Bioanalytical Chemistry. https://doi.org/10.1007/s00216-025-05755-w
Witherspoon, J. G., Hall, J. R., Jima, D., Atkins, H. M., Wamsley, N. T., Major, M. B., … Smart, R. C. (2024). Mutant Nrf2E79Q enhances the promotion and progression of a subset of oncogenic Ras keratinocytes and skin tumors. REDOX BIOLOGY, 75. https://doi.org/10.1016/j.redox.2024.103261
House, J. S., Gray, S., Owen, J. R., Jima, D. D., Smart, R. C., & Hall, J. R. (2023). C/EBP beta deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors. INNATE IMMUNITY, 29(1-2), 14–24. https://doi.org/10.1177/17534259231162192
Kaur, P., Barnes, R., Pan, H., Detwiler, A. C., Liu, M., Mahn, C., … Wang, H. (2021). TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA. NUCLEIC ACIDS RESEARCH, 49(22), 13000–13018. https://doi.org/10.1093/nar/gkab1142
Kotlarz, N., McCord, J., Collier, D., Lea, C. S., Strynar, M., Lindstrom, A. B., … Hoppin, J. A. (2020). Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina. ENVIRONMENTAL HEALTH PERSPECTIVES, 128(7). https://doi.org/10.1289/EHP6837
Tam, H. W., Hall, J. R., Messenger, Z. J., Jima, D. D., House, J. S., Linder, K., & Smart, R. C. (2019). C/EBP beta suppresses keratinocyte autonomous type 1 IFN response and p53 to increase cell survival and susceptibility to UVB-induced skin cancer. CARCINOGENESIS, 40(9), 1099–1109. https://doi.org/10.1093/carcin/bgz012
Messenger, Z. J., Hall, J. R., Jima, D. D., House, J. S., Tam, H. W., Tokarz, D. A., & Smart, R. C. (2018). C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death & Disease, 9(11). https://doi.org/10.1038/S41419-018-1103-Y
Smart, R. C., & Hall, J. R. (2018). Carcinogenesis. In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (5th ed.). Hoboken, NJ: J Wiley and Sons.
Tsuji, Y., & Smart, R. C. (2018). Molecular Techniques in the Study of Gene Function. In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (5th ed.). Hoboken, NJ: J Wiley and Sons.
Smart, R. C., & Hodgson, E. (Eds.). (2018). Molecular and Biochemical Toxicology (5th ed.). Hoboken, NJ: J. Wiley and Sons.
Molecular and Biochemical Toxicology (5th ed.). (2018). (ed.). J. Wiley and Sons.
Smart, R. C., & Hodgson, E. (2018). Molecular and Biochemical Toxicology: Definition and Scope. In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (5th ed.). Hoboken, NJ: J Wiley and Sons.
Hall, J. R., Messenger, Z. J., Tam, H. W., Phillips, S. L., Recio, L., & Smart, R. C. (2015). Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes. CELL DEATH & DISEASE, 6. https://doi.org/10.1038/cddis.2015.67
Hall, J. R., Bereman, M. S., Nepomuceno, A. I., Thompson, E. A., Muddiman, D. C., & Smart, R. C. (2014). C/EBPα regulates CRL4Cdt2-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint. Cell Cycle, 13(22), 3602–3610. https://doi.org/10.4161/15384101.2014.962957
Thompson, E. A., Zhu, S., Hall, J. R., House, J. S., Ranjan, R., Burr, J. A., … Smart, R. C. (2011). C/EBP alpha Expression Is Downregulated in Human Nonmelanoma Skin Cancers and Inactivation of C/EBP alpha Confers Susceptibility to UVB-Induced Skin Squamous Cell Carcinomas. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 131(6), 1339–1346. https://doi.org/10.1038/jid.2011.31
Gaddameedhi, S., Selby, C. P., Kaufmann, W. K., Smart, R. C., & Sancar, A. (2011). Control of skin cancer by the circadian rhythm. Proceedings of the National Academy of Sciences, 108(46), 18790–18795. https://doi.org/10.1073/pnas.1115249108
Ming, M., Feng, L., Shea, C. R., Soltani, K., Zhao, B., Han, W., … He, Y.-Y. (2011). PTEN Positively Regulates UVB-Induced DNA Damage Repair. CANCER RESEARCH, 71(15), 5287–5295. https://doi.org/10.1158/0008-5472.can-10-4614
Omori, E., Matsumoto, K., Zhu, S., Smart, R. C., & Ninomiya-Tsuji, J. (2010). Ablation of TAK1 Upregulates Reactive Oxygen Species and Selectively Kills Tumor Cells. Cancer Research, 70(21), 8417–8425. https://doi.org/10.1158/0008-5472.can-10-1227
House, J. S., Zhu, S., Ranjan, R., Linder, K., & Smart, R. C. (2010). C/EBP alpha and C/EBP beta Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin. PLOS ONE, 5(3). https://doi.org/10.1371/journal.pone.0009837
Deterding, L. J., Williams, J. G., Humble, M. M., Petrovich, R. M., Wei, S.-J., Trempus, C. S., … Tomer, K. B. (2011). CD34 antigen: Determination of specific sites of phosphorylation in vitro and in vivo. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 301(1-3), 12–21. https://doi.org/10.1016/j.ijms.2010.05.027
Smart, R. C. (2010). Chemical Carcinogenesis and Mutagenesis. In E. Hodgson (Ed.), Modern Toxicology (4th ed.). New York: J. Wiley and Sons.
Kim, T.-H., Chiera, S. L., Linder, K. E., Trempus, C. S., Smart, R. C., & Horowitz, J. M. (2010). Overexpression of Transcription Factor Sp2 Inhibits Epidermal Differentiation and Increases Susceptibility to Wound- and Carcinogen-Induced Tumorigenesis. CANCER RESEARCH, 70(21), 8507–8516. https://doi.org/10.1158/0008-5472.can-10-1213
Lee, S., Shuman, J. D., Guszczynski, T., Sakchaisri, K., Sebastian, T., Copeland, T. D., … Johnson, P. F. (2010). RSK-Mediated Phosphorylation in the C/EBP beta Leucine Zipper Regulates DNA Binding, Dimerization, and Growth Arrest Activity. MOLECULAR AND CELLULAR BIOLOGY, 30(11), 2621–2635. https://doi.org/10.1128/mcb.00782-09
Ranjan, R., Thompson, E. A., Yoon, K., & Smart, R. C. (2009). C/EBP alpha expression is partially regulated by C/EBP beta in response to DNA damage and C/EBP alpha-deficient fibroblasts display an impaired G(1) checkpoint. ONCOGENE, 28(36), 3235–3245. https://doi.org/10.1038/onc.2009.176
Ewing, S. J., Zhu, S., Zhu, F., House, J. S., & Smart, R. C. (2008). C/EBP beta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf). CELL DEATH AND DIFFERENTIATION, 15(11), 1734–1744. https://doi.org/10.1038/cdd.2008.105
Smart, R. C., Ewing, S. J., & Loomis, K. D. (2008). Carcinogenesis. In Molecular and Biochemical Toxicology (4th ed., pp. 537–586). https://doi.org/10.1002/9780470285251.ch24
Loomis, K. D., Zhu, S., Yoon, K., Johnson, P. F., & Smart, R. C. (2007). Genetic ablation of CCAAT/Enhancer binding protein alpha in epidermis reveals its role in suppression of epithelial tumorigenesis. CANCER RESEARCH, 67(14), 6768–6776. https://doi.org/10.1158/0008-5472.CAN-07-0139
Smart, R. C., & Hodgson, E. (Eds.). (2008). Molecular and Biochemical Toxicology. https://doi.org/10.1002/9780470285251
Hodgson, E., & Smart, R. C. (2008). Molecular and Biochemical Toxicology: Definition and Scope. In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (4th ed., pp. 1–4). https://doi.org/10.1002/9780470285251.ch1
Smart, R. C. (2008). Overview of Molecular Techniques in Toxicology: Genes and Transgenes. In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (4th ed., pp. 5–24). https://doi.org/10.1002/9780470285251.ch2
Yoon, K., Zhu, S., Ewing, S. J., & Smart, R. C. (2007). Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function. ONCOGENE, 26(3), 360–367. https://doi.org/10.1038/sj.onc.1209797
Omori, E., Matsumoto, K., Sanjo, H., Sato, S., Akira, S., Smart, R. C., & Ninomiya-Tsuji, J. (2006). TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(28), 19610–19617. https://doi.org/10.1074/jbc.M603384200
Sterneck, E., Zhu, S., Ramirez, A., Jorcano, J. L., & Smart, R. C. (2006). Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis. ONCOGENE, 25(8), 1272–1276. https://doi.org/10.1038/sj.onc.1209144
Shim, M., Powers, K. L., Ewing, S. J., Zhu, S., & Smart, R. C. (2005). Diminished expression of C/EBP alpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBP alpha in carcinoma cells inhibits proliferation. Cancer Research, 65(3), 861–867.
Yoon, K., & Smart, R. C. (2004). C/EBP alpha is a DNA damage-inducible p53-regulated mediator of the G(1) checkpoint in keratinocytes. MOLECULAR AND CELLULAR BIOLOGY, 24(24), 10650–10660. https://doi.org/10.1128/MCB.24.24.10650-10660.2004
Shuman, J. D., Sebastian, T., Kaldis, P., Copeland, T. D., Zhu, S. Y., Smart, R. C., & Johnson, P. F. (2004). Cell cycle-dependent phosphorylation of C/EBP beta mediates oncogenic cooperativity between C/EBP beta and H-Ras(V12). MOLECULAR AND CELLULAR BIOLOGY, 24(17), 7380–7391. https://doi.org/10.1128/MCB.24.17.7380-7391.2004
Smart, R. C. (2004). Chemical Carcinogenesis. In E. Hodgson (Ed.), A Textbook of Modern Toxicology (pp. 225–250). https://doi.org/10.1002/0471646776.ch12
Hodgson, E., Leblanc, G. A., Meyer, S. A., & Smart, R. C. (2004). Introduction to Biochemical and Molecular Methods in Toxicology. In E. Hodgson (Ed.), A Textbook of Modern Toxicology (pp. 13–22). https://doi.org/10.1002/0471646776.ch2
Shim, M., & Smart, R. C. (2003). Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBP alpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity. JOURNAL OF BIOLOGICAL CHEMISTRY, 278(22), 19674–19681. https://doi.org/10.1074/jbc.M301356200
Smart, R. C., & Oh, H.-S. (2003). Method of treating alopecia. Washington, DC: U.S. Patent and Trademark Office.
Smart, R. C., & Oh, H.-S. (2003). Method of treating alopecia (Vol. 6, 555, 532). Vol. 6, 555, 532. Washington, DC: U.S. Patent and Trademark Office.
Porter, K. L., Chanda, S., Wang, H. Q., Gaido, K. W., Smart, R. C., & Robinette, C. L. (2002). 17 beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice. TOXICOLOGICAL SCIENCES, 69(1), 42–48. https://doi.org/10.1093/toxsci/69.1.42
Tiano, H. F., Loftin, C. D., Akunda, J., Lee, C. A., Spalding, J., Sessoms, A., … al. (2002). Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis. Cancer Research, 62(12), 3395–3401.
Hodgson, E., & Smart, R. C. (2001). Biochemical Toxicology: Definition and Scope. In E. Hodgson & R. C. Smart (Eds.), Introduction to Biochemical Toxicology (pp. 1–10). New York: J. Wiley and Sons.
Zhu, S. Y., Yoon, K., Sterneck, E., Johnson, P. F., & Smart, R. C. (2002). CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(1), 207–212. https://doi.org/10.1073/pnas.012437299
Smart, R. C., & Akunda, J. K. (2001). Carcinogenesis. In E. Hodgson & R. C. Smart (Eds.), Introduction to Biochemical Toxicology (3rd ed., pp. 343–398). New York: J. Wiley and Sons.
Hodgson, E., & Smart, R. C. (Eds.). (2001). Introduction to Biochemical Toxicology (3rd ed.). New York: J. Wiley and Sons.
Introduction to Biochemical Toxicology (3rd ed.). (2001). (ed.). J. Wiley and Sons.
Smart, R. C., & Oh, H.-S. (2001). Method of treating alopecia. Washington, DC: U.S. Patent and Trademark Office.
Smart, R. C., & Oh, H.-S. (2001). Method of treating alopecia (Vol. 6, 204, 258). Vol. 6, 204, 258. Washington, DC: U.S. Patent and Trademark Office.
Smart, R. C. (2001). Molecular Techniques in Toxicology. In E. Hodgson & R. C. Smart (Eds.), Introduction to Biochemical Toxicology (3rd ed., pp. 11–32). New York: J. Wiley and Sons.
Wang, H. Q., Kim, M. P., Tiano, H. F., Langenbach, R., & Smart, R. C. (2001). Protein kinase C-alpha coordinately regulates cytosolic phospholipase A(2) activity and the expression of cyclooxygenase-2 through different mechanisms in mouse keratinocytes. MOLECULAR PHARMACOLOGY, 59(4), 860–866. https://doi.org/10.1124/mol.59.4.860
Chanda, S., Robinette, C. L., Couse, J. F., & Smart, R. C. (2000). 17 beta-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-alpha pathway. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 278(2), E202–E210. https://doi.org/10.1152/ajpendo.2000.278.2.e202
Owens, D. M., Wei, S. J. C., & Smart, R. C. (1999). A multihit, multistage model of chemical carcinogenesis. CARCINOGENESIS, 20(9), 1837–1844. https://doi.org/10.1093/carcin/20.9.1837
Zhu, S. Y., Oh, H. S., Shim, M., Sterneck, E., Johnson, P. F., & Smart, R. (1999). C/EBP beta modulates the early events of keratinocyte differentiation involving growth arrest and keratin 1 and keratin 10 expression. Molecular and Cellular Biology, 19(10), 7181–7190. https://doi.org/10.1128/mcb.19.10.7181
Matsuura, H., Adachi, H., Smart, R. C., Xu, X. C., Arata, J., & Jetten, A. M. (1999). Correlation between expression of peroxisome proliferator-activated receptor beta and squamous differentiation in epidermal and tracheobronchial epithelial cells. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 147(1-2), 85–92. https://doi.org/10.1016/S0303-7207(98)00214-7
Smart, R. C., Oh, H. S., Chanda, S., & Robinette, C. L. (1999, December). Effects of 17-beta-estradiol and ICI 182 780 on hair growth in various strains of mice. JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, Vol. 4, pp. 285–289. https://doi.org/10.1038/sj.jidsp.5640231
Smart, R. C., & Oh, H.-S. (1999). Methods of treating alopecia. Washington, DC: U.S. Patent and Trademark Office.
Smart, R. C., & Oh, H.-S. (1999). Methods of treating alopecia (Vol. 5, 965, 551). Vol. 5, 965, 551. Washington, DC: U.S. Patent and Trademark Office.
Wang, H. Q., & Smart, R. C. (1999). Overexpression of protein kinase C-[alpha] in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2, and TNF-[alpha] but not tumor promotion. Journal of Cell Science, 112(20), 3497–3506.
Oh, H. S., & Smart, R. C. (1998). Expression of CCAAT/enhancer binding proteins (C/EBP) is associated with squamous differentiation in epidermis and isolated primary keratinocytes and is altered in neoplasms. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 110(6), 939–945. https://doi.org/10.1046/j.1523-1747.1998.00199.x
Smart, R. C., & Oh, H. S. (1998, July). On the effect of estrogen receptor agonists and antagonists on the mouse hair follicle cycle. https://doi.org/10.1046/j.1523-1747.1998.00257.x
Kim, T. W., Porter, K. L., Foley, J. F., Maronpot, R. R., & Smart, R. (1997). Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha ras genotype. Molecular Carcinogenesis, 20(1), 115–124. https://doi.org/10.1002/(SICI)1098-2744(199709)20:1<115::AID-MC13>3.0.CO;2-4
Oh, H. S., & Smart, R. C. (1996). An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proceedings of the National Academy of Sciences, 93(22), 12525–12530. https://doi.org/10.1073/pnas.93.22.12525
Goodell, A. L., Oh, H.-S., Meyer, S. A., & Smart, R. C. (1996). Epidermal Protein Kinase C-β2 Is Highly Sensitive to Downregulation and Is Exclusively Expressed in Langerhans Cells: Downregulation Is Associated with Attenuated Contact Hypersensitivity. Journal of Investigative Dermatology, 107(3), 354–359. https://doi.org/10.1111/1523-1747.ep12363325
Owens, D. M., Jetten, A. M., Smart, R. C., & Zainal, T. A. (1996). Localization and Expression of Cornifin-α/SPRR1 in Mouse Epidermis, Anagen Follicles, and Skin Neoplasms. Journal of Investigative Dermatology, 106(4), 647–654. https://doi.org/10.1111/1523-1747.ep12345463
Owens, D. M., Spalding, J. W., Tennant, R. W., & Smart, R. C. (1995). Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin. Cancer Research, 55(14), 3171–3178.
Kim, T.-W., & Smart, R. C. (1995). Lack of effect of retinoic acid and fluocinolone acetonide on mirex tumor promotion indicates a novel mirex mechanism. Carcinogenesis, 16(9), 2199–2204. https://doi.org/10.1093/carcin/16.9.2199
MEYER, S. A., KIM, T. W., MOSER, G. J., MONTEIRORIVIERE, N. A., & SMART, R. C. (1994). SYNERGISTIC INTERACTION BETWEEN THE NONPHORBOL ESTER-TYPE PROMOTER MIREX AND 12-O-TETRADECANOYLPHORBOL-13-ACETATE IN MOUSE SKIN TUMOR PROMOTION. CARCINOGENESIS, 15(1), 47–52. https://doi.org/10.1093/carcin/15.1.47
Smart, R. C. (1993). Carcinogenesis. In E. Hodgson & P. E. Levi (Eds.), Biochemical Toxicology (2nd ed., pp. 381–414). Norwalk, CT: Appleton and Lange.
Colapietro, A.-M., Goodell, A. L., & Smart, R. C. (1993). Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels. Carcinogenesis, 14(11), 2289–2295. https://doi.org/10.1093/carcin/14.11.2289
Moser, G. J., Robinette, C. L., & Smart, R. C. (1993). Characterization of skin tumor promotion by mirex: structure-activity relationships, sexual dimorphism and presence of Ha-ras mutation. Carcinogenesis, 14(6), 1155–1160. https://doi.org/10.1093/carcin/14.6.1155
Mills, K. J., Reynolds, S. H., & Smart, R. C. (1993). Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes. Carcinogenesis, 14(12), 2645–2648. https://doi.org/10.1093/carcin/14.12.2645
MEYER, S. A., MOSER, G. J., MONTEIRORIVIERE, N. A., & SMART, R. C. (1993, December). MINIMAL ROLE OF ENHANCED CELL-PROLIFERATION IN SKIN TUMOR PROMOTION BY MIREX - A NONPHORBOL ESTER-TYPE PROMOTER. ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 101, pp. 265–269. https://doi.org/10.2307/3431879
Mills, K. J., Bocckino, S. B., Burns, D. J., Loomis, C. R., & Smart, R. C. (1992). Alterations in protein kinase C isozymes α and β2 in activated Ha-ras containing papillomas in the absence of an increase in diacyiglycerol. Carcinogenesis, 13(7), 1113–1120. https://doi.org/10.1093/carcin/13.7.1113
Moser, G. J., Meyer, S. A., & Smart, R. C. (1992). The chlorinated pesticide, mirex is a novel non-phorbol ester tumor promoter in mouse skin. Cancer Research, 52(3), 631–636.
SMART, R. C., & CRAWFORD, C. L. (1991). EFFECT OF ASCORBIC-ACID AND ITS SYNTHETIC LIPOPHILIC DERIVATIVE ASCORBYL PALMITATE ON PHORBOL ESTER INDUCED SKIN-TUMOR PROMOTION IN MICE. AMERICAN JOURNAL OF CLINICAL NUTRITION, 54(6), S1266–S1273. https://doi.org/10.1093/ajcn/54.6.1266s
Smart, R. C., & Moser, G. J. (1991). Pesticides, tumor promotion and risk assessment in Pesticides and the Future: Toxicological Studies of Risks and Benefits. In E. Hodgson, R. M. Roe, & N. Motoyama (Eds.), Reviews in Pesticides I (pp. 349–357).
Hansen, L. A., Monteiro-Riviere, N. A., & Smart, R. C. (1990). Differential down-regulation of epidermal protein kinase C (PKC) by tetradecanoylphorbol-13-acetate and diacylglycerol: Association with epidermal hyperplasia and tumor promotion. Cancer Research, 50, 5740–5745.
Mills, K. J., & Smart, R. C. (1989). Comparison of epidermal protein kinase C activity, ornithine decarboxylase induction and DNA synthesis stimulated by TPA or dioctanoylglycerol in mouse strains with differing susceptibility to TPA-induced tumor promotion. Carcinogenesis, 10(5), 833–838. https://doi.org/10.1093/carcin/10.5.833
Moser, G. J., & Smart, R. C. (1989). Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity. Carcinogenesis, 10(5), 851–856. https://doi.org/10.1093/carcin/10.5.851
Smart, R. C., Mills, K. J., Hansen, L. A., & Conney, A. H. (1989). Synthetic lipid second messenger, sn-1,2-didecanoylglycerol: A complete tumor promoter in mouse skin. Cancer Research, 49(16), 4455–4458.
SMART, R. C., HUANG, M. T., MONTEIRORIVIERE, N. A., WONG, C. Q., MILLS, K. J., & CONNEY, A. H. (1988). COMPARISON OF THE EFFECT OF SN-1,2-DIDECANOYLGLYCEROL AND 12-O-TETRADECANOYLPHORBOL-13-ACETATE ON CUTANEOUS MORPHOLOGY, INFLAMMATION AND TUMOR PROMOTION IN CD-1 MICE. CARCINOGENESIS, 9(12), 2221–2226. https://doi.org/10.1093/carcin/9.12.2221
Huang, M. T., Smart, R. C., Wong, C. Q., & Conney, A. H. (1988). Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-o-tetradecanoylphorbol-13-acetate. Cancer Research, 48(21), 5941–5946.
Zannoni, V. G., Brodfuehrer, J. I., Smart, R. C., & Susick, R. L. (1987). Ascorbic Acid, Alcohol, and Environmental Chemicals. Annals of the New York Academy of Sciences, 498(1 Third Confere), 364–388. https://doi.org/10.1111/j.1749-6632.1987.tb23775.x
Huang, M.-T., Smart, R. C., Thomas, P. E., Pickett, C. B., & Lu, Y. H. (1987). Characterization of purified DT-diaphorase from liver cytosol of 3-methylcholanthrene-treated rats. Chemica Scripta, 27A:49-54.
Smart, R. C., Huang, M.-T., Han, Z. T., Kaplan, M. C., Focella, A., & Conney, A. H. (1987). Inhibition of 12-O-Tetradecanoylphorbol-13-acetate Induction of Ornithine Decarboxylase Activity, DNA Synthesis, and Tumor Promotion in Mouse Skin by Ascorbic Acid and Ascorbyl Palmitate. Cancer Research, 47(24, Part 1), 6633–6638.
Smart, R. C., Huang, M.-T., Chang, R. L., Sayer, J. M., Jerina, D. M., & Conney, A. H. (1986). Disposition of the naturally occurring antimutagenic plant phenol, ellagic acid, and its synthetic derivatives, 3-O-decylellagic acid and 3, 3'-di-O-methylellagic acid in mice. Carcinogenesis, 7(10), 1663–1667. https://doi.org/10.1093/carcin/7.10.1663
Smart, R. C., & Zannoni, V. G. (1986). Effect of dietary ascorbate on covalent binding of benzene to bone marrow and hepatic tissue in vivo. Biochemical Pharmacology, 35(18), 3180–3182. https://doi.org/10.1016/0006-2952(86)90409-0
Smart, R. C., Huang, M.-T., Chang, R. L., Sayer, J. M., Jerina, D. M., Wood, A. W., & Conney, A. H. (1986). Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice. Carcinogenesis, 7(10), 1669–1675. https://doi.org/10.1093/carcin/7.10.1669
Smart, R. C., Huang, M.-T., & Conney, A. H. (1986). sn-l, 2-Diacylglycerols mimic the effects of 12-0-tetradecanoylphorbol-13-acetate in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis. Carcinogenesis, 7(11), 1865–1870. https://doi.org/10.1093/carcin/7.11.1865
Smart, R. C., & Zannoni, V. G. (1985). Effect of ascorbate on covalent binding of benzene and phenol metabolites to isolated tissue preparations. Toxicology and Applied Pharmacology, 77(2), 334–343. https://doi.org/10.1016/0041-008x(85)90333-3
Zannoni, V. G., Susick, R. L., & Smart, R. C. (1984). Ascorbic acid as it relates to the metabolism of drugs and environmental chemicals. In M. Wimick (Ed.), Nutrition in the 20th Century (pp. 21–36). New York: John Wiley and Sons.
Smart, R. C., & Zannoni, V. G. (1984). DT-Diaphorase and peroxidase influence the covalent binding of the metabolites of phenol, the major metabolite of benzene. Molecular Pharmacology, 26(1), 105–111.