Ralph Dewey

Dewey, R. E., Selote, D., Griffin, H. C., Dickey, A. N., Jantz, D., Smith, J. J., … Smith, W. A. (2023). Cytoplasmic male sterility and abortive seed traits generated through mitochondrial genome editing coupled with allotopic expression of atp1 in tobacco. FRONTIERS IN PLANT SCIENCE, 14. https://doi.org/10.3389/fpls.2023.1253640

Bovet, L., Campanoni, P., Lu, J., Hilfiker, A., Kleinhans, S., Laparra, H., … Goepfert, S. (2022). CLCNt2 Mediates Nitrate Content in Tobacco Leaf, Impacting the Production of Tobacco-Specific Nitrosamines in Cured Leaves. FRONTIERS IN PLANT SCIENCE, 13. https://doi.org/10.3389/fpls.2022.741078

Smith, W. A., Matsuba, Y., & Dewey, R. E. (2022). Knockout of a key gene of the nicotine biosynthetic pathway severely affects tobacco growth under field, but not greenhouse conditions. BMC RESEARCH NOTES, 15(1). https://doi.org/10.1186/s13104-022-06188-9

Lu, J., Chandrakanth, N. N., Lewis, R. S., Andres, K., Bovet, L., Goepfert, S., & Dewey, R. E. (2021). Constitutive activation of nitrate reductase in tobacco alters flowering time and plant biomass. SCIENTIFIC REPORTS, 11(1). https://doi.org/10.1038/s41598-021-83797-7

Lin, S., Dewey, R. E., Wang, R., Yu, J., Long, M., Zhang, J., … Ren, X. (2021). Discovery of a naturally-occurring allele of eIF4E1.S in Nicotiana tabacum and development of a co-dominant marker. EUPHYTICA, 217(7). https://doi.org/10.1007/s10681-021-02876-y

Lin, S., Dewey, R. E., Wang, R., Ren, X., Wang, Z., Zhang, J., & Long, M. (2021, June 22). Discovery of a novel eIF4E1.S allele conferring PVY resistance in Chinese tobacco (Nicotiana tabacum) landraces. PLANT BREEDING. https://doi.org/10.1111/pbr.12919

Wu, Q., La Hovary, C., Chen, H.-Y., Li, X., Eng, H., Vallejo, V., … Dewey, R. E. (2020). An Efficient Stevia rebaudiana Transformation System and In vitro Enzyme Assays Reveal Novel Insights into UGT76G1 Function. SCIENTIFIC REPORTS, 10(1). https://doi.org/10.1038/s41598-020-60776-y

Lewis, R. S., Drake-Stowe, K. E., Heim, C., Steede, T., Smith, W., & Dewey, R. E. (2020). Genetic and Agronomic Analysis of Tobacco Genotypes Exhibiting Reduced Nicotine Accumulation Due to Induced Mutations in Berberine Bridge Like (BBL) Genes. FRONTIERS IN PLANT SCIENCE, 11. https://doi.org/10.3389/fpls.2020.00368

Dluge, K. L., Song, Z., Wang, B., Steede, W. T., Xiao, B., Liu, Y., & Dewey, R. E. (2018). Characterization of Nicotiana tabacum genotypes possessing deletion mutations that affect potyvirus resistance and the production of trichome exudates. BMC GENOMICS, 19. https://doi.org/10.1186/s12864-018-4839-y

Lu, J., Zhang, L., Lewis, R. S., Bovet, L., Goepfert, S., Jack, A. M., … Dewey, R. E. (2016). Expression of a constitutively active nitrate reductase variant in tobacco reduces tobacco-specific nitrosamine accumulation in cured leaves and cigarette smoke. PLANT BIOTECHNOLOGY JOURNAL, 14(7), 1500–1510. https://doi.org/10.1111/pbi.12510

Patel, M., Milla-Lewis, S., Zhang, W., Templeton, K., Reynolds, W. C., Richardson, K., … Sathish, P. (2015). Overexpression of ubiquitin-like LpHUB1 gene confers drought tolerance in perennial ryegrass. PLANT BIOTECHNOLOGY JOURNAL, 13(5), 689–699. https://doi.org/10.1111/pbi.12291

Lewis, R. S., Lopez, H. O., Bowen, S. W., Andres, K. R., Steede, W. T., & Dewey, R. E. (2015). Transgenic and Mutation-Based Suppression of a Berberine Bridge Enzyme-Like (BBL) Gene Family Reduces Alkaloid Content in Field-Grown Tobacco. PLOS ONE, 10(2). https://doi.org/10.1371/journal.pone.0117273

Cardinal, A. J., Whetten, R., Wang, S., Auclair, J., Hyten, D., Cregan, P., … Burton, J. W. (2014). Mapping the low palmitate fap1 mutation and validation of its effects in soybean oil and agronomic traits in three soybean populations. THEORETICAL AND APPLIED GENETICS, 127(1), 97–111. https://doi.org/10.1007/s00122-013-2204-8

Cai, B., Jack, A. M., Lewis, R. S., Dewey, R. E., & Bush, L. P. (2013). (R)-nicotine biosynthesis, metabolism and translocation in tobacco as determined by nicotine demethylase mutants. PHYTOCHEMISTRY, 95, 188–196. https://doi.org/10.1016/j.phytochem.2013.06.012

Zhang, W.-J., Dewey, R. E., Boss, W., Phillippy, B. Q., & Qu, R. (2013). Enhanced Agrobacterium-mediated transformation efficiencies in monocot cells is associated with attenuated defense responses. PLANT MOLECULAR BIOLOGY, 81(3), 273–286. https://doi.org/10.1007/s11103-012-9997-8

Patel, M., Dewey, R. E., & Qu, R. (2013). Enhancing Agrobacterium tumefaciens-mediated transformation efficiency of perennial ryegrass and rice using heat and high maltose treatments during bacterial infection. PLANT CELL TISSUE AND ORGAN CULTURE, 114(1), 19–29. https://doi.org/10.1007/s11240-013-0301-7

Dewey, R. E., & Xie, J. (2013). [Review of Molecular genetics of alkaloid biosynthesis in Nicotiana tabacum]. PHYTOCHEMISTRY, 94, 10–27. https://doi.org/10.1016/j.phytochem.2013.06.002

Li, D., Lewis, R. S., Jack, A. M., Dewey, R. E., Bowen, S. W., & Miller, R. D. (2012). Development of CAPS and dCAPS markers for CYP82E4, CYP82E5v2 and CYP82E10 gene mutants reducing nicotine to nornicotine conversion in tobacco. MOLECULAR BREEDING, 29(3), 589–599. https://doi.org/10.1007/s11032-011-9575-9

Cai, B., Siminszky, B., Chappell, J., Dewey, R. E., & Bush, L. P. (2012). Enantioselective Demethylation of Nicotine as a Mechanism for Variable Nornicotine Composition in Tobacco Leaf. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(51), 42804–42811. https://doi.org/10.1074/jbc.m112.413807

Cardinal, A. J., Burton, J. W., Camacho-Roger, A. M., Whetten, R., Chappell, A. S., Bilyeu, K. D., … Dewey, R. E. (2011). Molecular Analysis of GmFAD3A in Two Soybean Populations Segregating for the fan, fap1, and fap(nc) Loci. CROP SCIENCE, 51(5), 2104–2112. https://doi.org/10.2135/cropsci2010.08.0500

De Vries, B. D., Fehr, W. R., Welke, G. A., & Dewey, R. E. (2011). Molecular Analysis of Mutant Alleles for Elevated Palmitate Concentration in Soybean. CROP SCIENCE, 51(6), 2554–2560. https://doi.org/10.2135/cropsci2011.03.0156

De Vries, B. D., Fehr, W. R., Welke, G. A., & Dewey, R. E. (2011). Molecular Characterization of the Mutant fap3(A22) Allele for Reduced Palmitate Concentration in Soybean. CROP SCIENCE, 51(4), 1611–1616. https://doi.org/10.2135/cropsci2010.10.0619

Lewis, R. S., Bowen, S. W., Keogh, M. R., & Dewey, R. E. (2010). Three nicotine demethylase genes mediate nornicotine biosynthesis in Nicotiana tabacum L Functional characterization of the CYP82E10 gene. PHYTOCHEMISTRY, 71(17-18), 1988–1998. https://doi.org/10.1016/j.phytochem.2010.09.011

Keogh, M. R., Courtney, P. D., Kinney, A. J., & Dewey, R. E. (2009). Functional Characterization of Phospholipid N-Methyltransferases from Arabidopsis and Soybean. JOURNAL OF BIOLOGICAL CHEMISTRY, 284(23), 15439–15447. https://doi.org/10.1074/jbc.M109.005991

Bachlava, E., Dewey, R. E., Burton, J. W., & Cardinal, A. J. (2009). Mapping and Comparison of Quantitative Trait Loci for Oleic Acid Seed Content in Two Segregating Soybean Populations. CROP SCIENCE, 49(2), 433–442. https://doi.org/10.2135/cropsci2008.06.0324

Bachlava, E., Dewey, R. E., Burton, J. W., & Cardinal, A. J. (2009). Mapping candidate genes for oleate biosynthesis and their association with unsaturated fatty acid seed content in soybean. MOLECULAR BREEDING, 23(2), 337–347. https://doi.org/10.1007/s11032-008-9246-7

Chakrabarti, M., Bowen, S. W., Coleman, N. P., Meekins, K. M., Dewey, R. E., & Siminszky, B. (2008). CYP82E4-mediated nicotine to nornicotine conversion in tobacco is regulated by a senescence-specific signaling pathway. PLANT MOLECULAR BIOLOGY, 66(4), 415–427. https://doi.org/10.1007/s11103-007-9280-6

Cardinal, A. J., Dewey, R. E., & Burton, J. W. (2008). Estimating the individual effects of the reduced palmitic acid fap(nc) and fap1 alleles on agronomic traits in two soybean populations. CROP SCIENCE, 48(2), 633–639. https://doi.org/10.2135/cropsci2007.05.0251

Bachlava, E., Dewey, R. E., Auclair, J., Wang, S., Burton, J. W., & Cardinal, A. J. (2008). Mapping genes encoding microsomal omega-6 desaturase enzymes and their cosegregation with QTL affecting oleate content in soybean. CROP SCIENCE, 48(2), 640–650. https://doi.org/10.2135/cropsci2007.07.0381

Zhang, P., Burton, J. W., Upchurch, R. G., Whittle, E., Shanklin, J., & Dewey, R. E. (2008). Mutations in a Delta(9)-Stearoyl-ACP-Desaturase Gene Are Associated with Enhanced Stearic Acid Levels in Soybean Seeds. CROP SCIENCE, 48(6), 2305–2313. https://doi.org/10.2135/cropsci2008.02.0084

Lewis, R. S., Jack, A. M., Morris, J. W., Robert, V. J. M., Gavilano, L. B., Siminszky, B., … Dewey, R. E. (2008). RNA interference (RNAi)-induced suppression of nicotine demethylase activity reduces levels of a key carcinogen in cured tobacco leaves. PLANT BIOTECHNOLOGY JOURNAL, 6(4), 346–354. https://doi.org/10.1111/j.1467-7652.2008.00324.x

Irsigler, A. S. T., Costa, M. D., Zhang, P., Reis, P. A. B., Dewey, R. E., Boston, R. S., & Fontes, E. P. B. (2007). Expression profiling on soybean leaves reveals integration of ER- and osmotic-stress pathways. BMC GENOMICS, 8. https://doi.org/10.1186/1471-2164-8-431

Cardinal, A. J., Burton, J. W., Camacho-Roger, A. M., Yang, J. H., Wilson, R. F., & Dewey, R. E. (2007). Molecular analysis of soybean lines with low palmitic acid content in the seed oil. CROP SCIENCE, 47(1), 304–310. https://doi.org/10.2135/cropsci2006.04.0272

Aghoram, K., Wilson, R. E., Burton, J. W., & Dewey, R. E. (2006). A mutation in a 3-keto-acyl-ACP synthase II gene is associated with elevated palmitic acid levels in soybean seeds. CROP SCIENCE, 46(6), 2453–2459. https://doi.org/10.2135/cropsci2006.04.0218

Siminszky, B., Gavilano, L., Bowen, S. W., & Dewey, R. E. (2005). Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase. Proceedings of the National Academy of Sciences of the United States of America, 102(41), 14919–14924. https://doi.org/10.1073/pnas.050658102

Siminszky, B., Gavilano, L., Bowen, S. W., & Dewey, R. E. (2005). Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase. Proceedings of the National Academy of Sciences, 102(41), 14919–14924. https://doi.org/10.1073/pnas.0506581102

Hernandez-Sebastia, C., Marsolais, F., Saravitz, C., Israel, D., Dewey, R. E., & Huber, S. C. (2005). Free amino acid profiles suggest a possible role for asparagine in the control of storage-product accumulation in developing seeds of low- and high-protein soybean lines. JOURNAL OF EXPERIMENTAL BOTANY, 56(417), 1951–1963. https://doi.org/10.1093/jxb/eri191

Tang, G. Q., Novitzky, W. P., Griffin, H. C., Huber, S. C., & Dewey, R. E. (2005). Oleate desaturase enzymes of soybean: evidence of regulation through differential stability and phosphorylation. PLANT JOURNAL, 44(3), 433–446. https://doi.org/10.1111/j.1365-313X.2005.02535.x

Tang, G. Q., Hardin, S. C., Dewey, R., & Huber, S. C. (2003). A novel C-terminal proteolytic processing of cytosolic pyruvate kinase, its phosphorylation and degradation by the proteasome in developing soybean seeds. PLANT JOURNAL, 34(1), 77–93. https://doi.org/10.1046/j.1365-313X.2003.01711.x

Siminszky, B., Freytag, A. M., Sheldon, B. S., & Dewey, R. E. (2003). Co-expression of a NADPH : P450 reductase enhances CYP71A10-dependent phenylurea metabolism in tobacco. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 77(2), 35–43. https://doi.org/10.1016/j.pestbp.2003.08.001

Wilson, R. F., Marquardt, T. C., Novitzky, W. P., Burton, J. W., Wilcox, JR, & Dewey, R. E. (2001). Effect of alleles governing 16 : 0 concentration on glycerolipid composition in developing soybeans. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 78(4), 329–334. https://doi.org/10.1007/s11746-001-0264-5

Monks, D. E., Aghoram, K., Courtney, P. D., DeWald, D. B., & Dewey, R. E. (2001). Hyperosmotic stress induces the rapid phosphorylation of a soybean phosphatidylinositol transfer protein homolog through activation of the protein kinases SPK1 and SPK2. PLANT CELL, 13(5), 1205–1219. https://doi.org/10.1105/tpc.13.5.1205

Shank, K. J., Su, P., Brglez, I., Boss, W. F., Dewey, R. E., & Boston, R. S. (2001). Induction of lipid metabolic enzymes during the endoplasmic reticulum stress response in plants. PLANT PHYSIOLOGY, 126(1), 267–277. https://doi.org/10.1104/pp.126.1.267

Wilson, R. F., Marquardt, T. C., Novitzky, W. P., Burton, J. W., Wilcox, JR, Kinney, A. J., & Dewey, R. E. (2001). Metabolic mechanisms associated with alleles governing the 16 : 0 concentration of soybean oil. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 78(4), 335–340. https://doi.org/10.1007/s11746-001-0265-4

Siminszky, B., Sheldon, B. S., Corbin, F. T., & Dewey, R. E. (2000). A cytochrome P450 monooxygenase cDNA (CYP71A10) confers resistance to linuron in transgenic Nicotiana tabacum. WEED SCIENCE, 48(3), 291–295. https://doi.org/10.1614/0043-1745(2000)048[0291:ACPMCC]2.0.CO;2

Pedra, J. H. F., Delu, N., Pirovani, C. P., Contim, L. A. S., Dewey, R. E., Otoni, W. C., & Fontes, E. P. B. (2000). Antisense and sense expression of a sucrose binding protein homologue gene from soybean in transgenic tobacco affects plant growth and carbohydrate partitioning in leaves. PLANT SCIENCE, 152(1), 87–98. https://doi.org/10.1016/S0168-9452(99)00223-X

Siminszky, B., Dewey, R., & Corbin, F. (2000). Cytochrome P-450 constructs and method of producing herbicide-resistant transgenic plants. Washington, DC: U.S. Patent and Trademark Office.

Goode, J. H., & Dewey, R. E. (1999). Characterization of aminoalcoholphosphotransferases from Arabidopsis thaliana and soybean. PLANT PHYSIOLOGY AND BIOCHEMISTRY, 37(6), 445–457. https://doi.org/10.1016/S0981-9428(99)80049-7

Siminszky, B., Corbin, F. T., Ward, E. R., Fleischmann, T. J., & Dewey, R. E. (1999). Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenylurea herbicides. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 96(4), 1750–1755. https://doi.org/10.1073/pnas.96.4.1750

Drobak, B. K., Dewey, R. E., & Boss, W. F. (1999). [Review of Phosphoinositide kinases and the synthesis of polyphosphoinositides in higher plant cells]. INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 189, 189, 95–130. https://doi.org/10.1016/S0074-7696(08)61386-8

Modified urf13-T protein. (1998). Washington, DC: U.S. Patent and Trademark Office.

Kearns, M. A., Monks, D. E., Fang, M., Rivas, M. P., Courtney, P. D., Chen, J., … Bankaitis, V. A. (1998). Novel developmentally regulated phosphoinositide binding proteins from soybean whose expression bypasses the requirement for an essential phosphatidylinositol transfer protein in yeast. EMBO JOURNAL, 17(14), 4004–4017. https://doi.org/10.1093/emboj/17.14.4004

Maize cytoplasmic male sterility type T (cms-T) mitochondria DNA. (1997). Washington, DC: U.S. Patent and Trademark Office.

Levings, C. S., Dewey, R. E., & Braun, C. J. (1997). Method of detecting toxins using host cells expressing an urf13-T gene. Washington, DC: U.S. Patent and Trademark Office.

Monks, D. E., Goode, J. H., Dinsmore, P. K., & Dewey, R. E. (1997). Phosphatidylcholine biosynthesis in soybeans: The cloning and characterization of genes encoding enzymes of the nucleotide pathway. In M. U. K. J. P. Williams & N. W. Lem (Eds.), Physiology, biochemistry, and molecular biology of plant lipids (pp. 110–112). https://doi.org/10.1007/978-94-017-2662-7_35

Levings, C. S., Dewey, R. E., & Braun, C. J. (1996). Method of detecting toxin-insensitive urf13-T protein. Washington, DC: U.S. Patent and Trademark Office.

Levings, C. S., Dewey, R. E., & Braun, C. J. (1995). Modified unF-13 protein and gene. Washington, DC: U.S. Patent and Trademark Office.

DEWEY, R. E., WILSON, R. F., NOVITZKY, W. P., & GOODE, J. H. (1994). THE AAPT1 GENE OF SOYBEAN COMPLEMENTS A CHOLINEPHOSPHOTRANSFERASE-DEFICIENT MUTANT OF YEAST. PLANT CELL, 6(10), 1495–1507. https://doi.org/10.1105/tpc.6.10.1495

DEWEY, R. E., TIMOTHY, D. H., & LEVINGS, C. S. (1991). CHIMERIC MITOCHONDRIAL GENES EXPRESSED IN THE C-MALE-STERILE CYTOPLASM OF MAIZE. CURRENT GENETICS, 20(6), 475–482. https://doi.org/10.1007/BF00334775

Dewey, R. E., Levings, C. S., & Timothy, D. H. (1986). Novel recombinations in the maize mitochondrial genome produce a unique transcriptional unit in the texas male-sterile cytoplasm. Cell, 44(3), 439–449. https://doi.org/10.1016/0092-8674(86)90465-4