Works (3)

Updated: July 5th, 2023 15:45

2019 journal article

Effects of Regulatory T Cell Depletion on NK Cell Responses against Listeria monocytogenes in Feline Immunodeficiency Virus Infected Cats

VIRUSES-BASEL, 11(11).

By: R. Simoes n, A. LaVoy n & G. Dean n

author keywords: feline immunodeficiency virus; NK cells; regulatory T cells; innate immunity; Treg depletion
MeSH headings : Animals; Cats; Dendritic Cells / immunology; Feline Acquired Immunodeficiency Syndrome / complications; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Female; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / physiology; Killer Cells, Natural / immunology; Listeria monocytogenes / immunology; Listeria monocytogenes / physiology; Listeriosis / immunology; Listeriosis / microbiology; Listeriosis / veterinary; Lymph Nodes / immunology; Lymphocyte Depletion; Opportunistic Infections / immunology; Opportunistic Infections / microbiology; Opportunistic Infections / veterinary; T-Lymphocytes, Regulatory / immunology
TL;DR: Treg depletion failed to improve the innate immune response of FIV-infected cats against Lm and this may be due to dendritic cell dysfunction. (via Semantic Scholar)
Source: Web Of Science
Added: December 30, 2019

2013 journal article

Infection with feline immunodeficiency Virus alters intestinal epithelial transport and mucosal immune responses to probiotics

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 153(1-2), 146–152.

By: L. Stoeker n, E. Overman n, S. Nordone n, A. Moeser n, R. Simoes n & G. Dean*

author keywords: HIV; FIV; Lactobacillus; Mucosal immune system
MeSH headings : Animals; Biological Transport; Cats; Electric Impedance; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / metabolism; Immunity, Mucosal / drug effects; Intestinal Mucosa / metabolism; Probiotics / pharmacology
TL;DR: A novel role for FIV in upregulating transcellular transport across the gastrointestinal epithelial barrier is suggested and the potential therapeutic use of probiotic bacteria to restore intestinal homeostasis is demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

In Vivo Assessment of Natural Killer Cell Responses during Chronic Feline Immunodeficiency Virus Infection

PLOS ONE, 7(5).

By: R. Simoes n, K. Howard n & G. Dean n

MeSH headings : Animals; Apoptosis; Cats; Cell Proliferation; Female; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / pathogenicity; Immunophenotyping; Killer Cells, Natural / immunology; Lentivirus Infections / immunology; Lentivirus Infections / virology; Leukocytes, Mononuclear / immunology; Male
TL;DR: The failure of the NK cell response against Lm challenge in the draining lymph node of FIV-infected cats correlates with the delayed control and clearance of this opportunistic bacterial pathogen. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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