Rachel Elizabeth Marceau

Works (3)

Updated: July 5th, 2023 15:40

2019 article

SA30VARIANCE COMPONENT TEST FOR CROSS-DISORDER PATHWAY ANALYSIS

Szatkiewicz, J., Marceau, R., Yilmaz, Z., Bulik, C., Crowley, J., Mattheisen, M., … al. (2019, January 1). European Neuropsychopharmacology, Vol. 29, pp. 1204–1205.

By: J. Szatkiewicz *, R. Marceau n, Z. Yilmaz *, C. Bulik *, J. Crowley *, M. Mattheisen *, P. Sullivan *, W. Lu n  ...

topics (OpenAlex): Genomics and Rare Diseases; Neurological disorders and treatments; Genetic Neurodegenerative Diseases
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2015 article

A Fast Multiple‐Kernel Method With Applications to Detect Gene‐Environment Interaction

Marceau, R., Lu, W., Holloway, S., Sale, M. M., Worrall, B. B., Williams, S. R., … Tzeng, J. Y. (2015, July 3). Genetic Epidemiology, Vol. 39, pp. 456–468.

By: R. Marceau n, W. Lu n , S. Holloway n, M. Sale *, B. Worrall *, S. Williams *, F. Hsu *, J. Tzeng n 

author keywords: multiple-kernel analysis; kernel machine regression; exon level association test; gene-environment interaction; gene-gene interactions
MeSH headings : Algorithms; Gene-Environment Interaction; Genetic Variation; Homocysteine / metabolism; Humans; Models, Genetic; Quantitative Trait Loci; Regression Analysis; Risk Factors; Software; Stroke / etiology; Vitamins / metabolism
topics (OpenAlex): Folate and B Vitamins Research; Genetic Associations and Epidemiology; MicroRNA in disease regulation
TL;DR: This work proposes a computationally efficient and statistically rigorous “fastKM” algorithm for multikernel analysis that is based on a low‐rank approximation to the nuisance effect kernel matrices and shows that it has similar performance to an EM‐based KM approach for quantitative traits while running much faster. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Assessing gene-environment interactions for common and rare variants with binary traits using gene-trait similarity regression

Genetics, 199(3), 695-.

By: G. Zhao, R. Marceau, D. Zhang & J. Tzeng 

Source: NC State University Libraries
Added: August 6, 2018

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