Works (33)

Updated: July 23rd, 2023 19:25

2020 journal article

The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis

JOURNAL OF MOLECULAR BIOLOGY, 432(2), 343โ€“357.

By: M. Miltonโ€‰*, G. Draughn n, B. Bobay n, S. Stowe n, A. Olson n, E. Feldmann n, R. Thompson*, K. Myers n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Biofilms; Bacillus subtilis; Transcriptional regulation; NMR solution structure
MeSH headings : Amino Acid Sequence / genetics; Bacillus subtilis / genetics; Bacillus subtilis / ultrastructure; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / ultrastructure; Biofilms / growth & development; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / ultrastructure; Gene Expression Regulation, Bacterial / genetics; Molecular Docking Simulation; Mutation / genetics; Protein Binding / genetics; Protein Conformation
Source: Web Of Science
Added: February 27, 2020

2018 journal article

The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism

Journal of Molecular Biology, 430(6), 806โ€“821.

By: G. Draughn n, M. Miltonโ€‰ n, E. Feldmann n, B. Bobay n, B. Roth*, A. Olson n, R. Thompson n, L. Actisโ€‰*, C. Davies*, J. Cavanagh*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / genetics; Acinetobacter baumannii / metabolism; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Biofilms / drug effects; Biofilms / growth & development; Cloning, Molecular; Crystallography, X-Ray; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Gene Expression Regulation, Bacterial; Models, Molecular; Phosphorylation; Promoter Regions, Genetic; Protein Conformation
Sources: Web Of Science, Crossref
Added: August 6, 2018

2015 journal article

Membrane-Permeabilizing Activity of Reverse-Amide 2-Aminoimidazole Antibiofilm Agents Against Acinetobacter baumannii

CURRENT DRUG DELIVERY, 12(2), 223โ€“230.

By: S. Stowe*, R. Thompson*, L. Peng*, Z. Su*, M. Blackledge*, G. Draughn, W. Coe, E. Johannes* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: 2-aminoimidazole; Acinetobacter baumannii; biofilm; membrane permeabilization; reverse amide; SEM
MeSH headings : Acinetobacter baumannii / drug effects; Amides / chemistry; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Cell Membrane Permeability / drug effects; Cells, Cultured; Cross Infection; Imidazoles / chemistry; Imidazoles / pharmacology; Microbial Sensitivity Tests
Source: Web Of Science
Added: August 6, 2018

2014 journal article

A DNA Mimic: The Structure and Mechanism of Action for the Anti-Repressor Protein AbbA

JOURNAL OF MOLECULAR BIOLOGY, 426(9), 1911โ€“1924.

By: A. Tucker n, B. Bobay n, A. Banse*, A. Olson n, E. Soderblom*, M. Moseleyโ€‰*, R. Thompson n, K. Varneyโ€‰*, R. Losick*, J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: transition state regulator; AbbA; DNA mimic; molecular docking; NMR
MeSH headings : Bacillus subtilis / chemistry; Bacillus subtilis / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Docking Simulation; Protein Conformation; Protein Multimerization
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Chemical shift assignments and secondary structure prediction of the C-terminal domain of the response regulator BfmR from Acinetobacter baumannii

BIOMOLECULAR NMR ASSIGNMENTS, 8(1), 67โ€“70.

By: A. Olson n, R. Thompson n, C. Melanderโ€‰ n & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: NMR; BfmR; Acinetobacter baumannii; Assignment
MeSH headings : Acinetobacter baumannii / metabolism; Bacterial Proteins / chemistry; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Protein Structure, Tertiary
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Chemical shift assignments and secondary structure prediction of the phosphorelay protein VanU from Vibrio anguillarum

BIOMOLECULAR NMR ASSIGNMENTS, 8(1), 177โ€“179.

By: B. Bobay n, R. Thompson n, D. Milton* & J. Cavanagh n

co-author countries: Sweden ๐Ÿ‡ธ๐Ÿ‡ช United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: VanU; NMR; Vibrio anguillarum; Phosphorelay
MeSH headings : Bacterial Proteins / chemistry; Nuclear Magnetic Resonance, Biomolecular; Phosphotransferases / chemistry; Protein Structure, Secondary; Vibrio / metabolism
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Small-Molecule Suppression of beta-Lactam Resistance in Multidrug-Resistant Gram-Negative Pathogens

JOURNAL OF MEDICINAL CHEMISTRY, 57(17), 7450โ€“7458.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Cell Line; Cell Survival / drug effects; Drug Resistance, Multiple, Bacterial / drug effects; Gram-Negative Bacteria / classification; Gram-Negative Bacteria / drug effects; Hemolysis / drug effects; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Microbial Sensitivity Tests; Sheep; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; beta-Lactam Resistance / drug effects
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Structure and DNA-Binding Traits of the Transition State Regulator AbrB

STRUCTURE, 22(11), 1650โ€“1656.

By: A. Olson n, A. Tucker n, B. Bobay n, E. Soderblom*, M. Moseleyโ€‰*, R. Thompson n, J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Bacillus subtilis / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Binding Sites; DNA, Bacterial / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / metabolism; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Docking Simulation; Protein Multimerization; Protein Structure, Secondary; Transcription Factors / chemistry; Transcription Factors / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems

DRUG AND CHEMICAL TOXICOLOGY, 35(3), 310โ€“315.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: 2-aminoimidazole; adjuvant; biofilm; Caenorhabditis elegans; toxicity; Toxicity of 2-aminoimidazole; antibiofilm agents
MeSH headings : Adjuvants, Pharmaceutic / toxicity; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / toxicity; Biofilms / drug effects; Caenorhabditis elegans; Cell Line; Dose-Response Relationship, Drug; Environmental Exposure; Fertility / drug effects; Humans; Imidazoles / pharmacology; Imidazoles / toxicity; Keratinocytes / metabolism; Tetrazolium Salts; Thiazoles; Toxicity Tests
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Identification of BfmR, a Response Regulator Involved in Biofilm Development, as a Target for a 2-Aminoimidazole-Based Antibiofilm Agent

BIOCHEMISTRY, 51(49), 9776โ€“9778.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Bacterial Proteins / chemistry; Bacterial Proteins / physiology; Biofilms / drug effects; Imidazoles / pharmacology; Microscopy, Confocal; Models, Molecular
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Structural insights into the calcium-dependent interaction between calbindin-D28K and caspase-3

FEBS LETTERS, 586(20), 3582โ€“3589.

By: B. Bobay n, A. Stewart n, A. Tucker n, R. Thompson n, K. Varneyโ€‰* & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Calbindin-D28K; Caspase-3; Isothermal titration calorimetry; Molecular docking
MeSH headings : Calbindins; Calcium / metabolism; Caspase 3 / chemistry; Caspase 3 / metabolism; Enzyme Activation; Hydrogen Bonding; Molecular Docking Simulation; Protein Binding; Protein Conformation; S100 Calcium Binding Protein G / chemistry; S100 Calcium Binding Protein G / metabolism
Source: Web Of Science
Added: August 6, 2018

2011 review

Anti-biofilm compounds derived from marine sponges

[Review of ]. Marine Drugs, 9(10), 2010โ€“2035.

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Long range dynamic effects of point-mutations trap a response regulator in an active conformation

FEBS LETTERS, 584(19), 4203โ€“4207.

By: B. Bobay n, R. Thompson n, J. Hoch* & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: NMR; Conformational transition; Intra-protein communication; Response regulator; Spo0F
MeSH headings : Bacillus subtilis / genetics; Bacillus subtilis / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins / chemistry; Mutant Proteins / genetics; Mutant Proteins / metabolism; Nuclear Magnetic Resonance, Biomolecular; Point Mutation; Principal Component Analysis; Protein Conformation; Second Messenger Systems / genetics; Signal Transduction / genetics; Thermodynamics
Source: Web Of Science
Added: August 6, 2018

2010 journal article

NMR Solution Structure and DNA-binding Model of the DNA-binding Domain of Competence Protein A

JOURNAL OF MOLECULAR BIOLOGY, 398(2), 248โ€“263.

By: C. Hobbs n, B. Bobay n, R. Thompson n, M. Perego* & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: competence; ComA; NMR; two-component; response regulator
MeSH headings : Amino Acid Sequence; Bacillus subtilis / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; DNA / chemistry; DNA / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Escherichia coli Proteins / chemistry; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Helix-Turn-Helix Motifs; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Structural Characterization of the Conformational Change in Calbindin-D-28k upon Calcium Binding Using Differential Surface Modification Analyzed by Mass Spectrometry

BIOCHEMISTRY, 48(36), 8603โ€“8614.

By: C. Hobbs n, L. Deterdingโ€‰*, L. Pereraโ€‰*, B. Bobay n, R. Thompson n, T. Darden*, J. Cavanagh n, K. Tomer*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amino Acid Sequence; Animals; Apoproteins / chemistry; Calbindin 1; Calbindins; Cysteine / chemistry; Disulfides / chemistry; EF Hand Motifs; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; S100 Calcium Binding Protein G / chemistry; S100 Calcium Binding Protein G / metabolism; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Structural and Motional Contributions of the Bacillus subtilis ClpC N-Domain to Adaptor Protein Interactions

JOURNAL OF MOLECULAR BIOLOGY, 387(3), 639โ€“652.

By: D. Kojetinโ€‰*, P. McLaughlin n, R. Thompson n, D. Dubnau, P. Prepiak, M. Rance*, J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: competence; adaptor protein proteosome interactions; HSP100/Clp N-domain; NMR dynamics
MeSH headings : Adaptor Proteins, Vesicular Transport / chemistry; Adaptor Proteins, Vesicular Transport / genetics; Adaptor Proteins, Vesicular Transport / metabolism; Amino Acid Sequence; Bacillus subtilis / genetics; Bacillus subtilis / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Heat-Shock Proteins / chemistry; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Secondary; Sequence Alignment; Static Electricity
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Insights into the Nature of DNA Binding of AbrB-like Transcription Factors

STRUCTURE, 16(11), 1702โ€“1713.

By: D. Sullivan n, B. Bobay n, D. Kojetinโ€‰*, R. Thompson n, M. Rance*, M. Strauch*, J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Bacillus subtilis / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Binding Sites; DNA / chemistry; DNA / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / metabolism; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Thermodynamics; Transcription Factors / chemistry; Transcription Factors / metabolism
Source: Web Of Science
Added: August 6, 2018

2007 journal article

NMR assignment of the N-terminal repeat domain of Bacillus subtilis ClpC

BIOMOLECULAR NMR ASSIGNMENTS, 1(2), 163โ€“165.

By: D. Kojetin*, P. McLaughlin n, R. Thompson n, R. Ventersโ€‰*, M. Rance* & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: ClpC; Bacillus subtilis; N-domain; genetic competence; HSP100/AAA+
MeSH headings : Amino Acid Sequence; Bacterial Proteins / chemistry; Connexins / chemistry; Heat-Shock Proteins / chemistry; Magnetic Resonance Spectroscopy / methods; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Peptide binding proclivities of calcium loaded calbindin-D28k

FEBS LETTERS, 581(24), 4778โ€“4782.

By: D. Kordys n, B. Bobay n, R. Thompson n, R. Ventersโ€‰* & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: calbindin-D28k; NMR; chemical shift; peptides; modeling
MeSH headings : Animals; Calbindin 1; Calbindins; Calcium / metabolism; Circular Dichroism; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptides / metabolism; Protein Binding; Protein Structure, Tertiary; Rats; S100 Calcium Binding Protein G / metabolism; Titrimetry
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition

FEBS LETTERS, 581(7), 1425โ€“1429.

By: P. McLaughlin n, B. Bobaya, E. Regel n, R. Thompson n, J. Hoch* & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: sporulation; kinases; Spo0F mutants
MeSH headings : Alanine / chemistry; Alanine / genetics; Amino Acid Sequence; Amino Acid Substitution; Bacillus subtilis / metabolism; Bacillus subtilis / physiology; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Histidine Kinase; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Interaction Mapping; Protein Kinases / chemistry; Protein Kinases / metabolism; Protein Structure, Secondary; Spores, Bacterial
Source: Web Of Science
Added: August 6, 2018

2006 journal article

NMR structure of AbhN and comparison with AbrBN - First insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins

JOURNAL OF BIOLOGICAL CHEMISTRY, 281(30), 21399โ€“21409.

By: B. Bobay n, G. Muellerโ€‰*, R. Thompson n, A. Murzin*, R. Ventersโ€‰*, M. Strauch*, J. Cavanagh n

co-author countries: United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amino Acid Sequence; Bacillus subtilis / enzymology; Bacterial Proteins / metabolism; Cloning, Molecular; DNA / chemistry; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / metabolism; Deoxyribonuclease I / chemistry; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Binding; Sequence Homology, Amino Acid; Transcription Factors / metabolism
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D-28K

Nature Structural & Molecular Biology, 13(7), 641โ€“647.

By: D. Kojetin, R. Venters, D. Kordys, R. Thompson, R. Kumar & J. Cavanagh

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Structural analysis of divalent metals binding to the Bacillus subtilis response regulator Spo0F: the possibility for In vitro metalloregulation in the initiation of sporulation

BIOMETALS, 18(5), 449โ€“466.

By: D. Kojetin n, R. Thompson n, L. Benson*, S. Naylor*, J. Waterman n, K. Daviesโ€‰*, C. Opperman n, K. Stephenson*, J. Hoch*, J. Cavanagh n

co-author countries: United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: metal binding; NMR spectroscopy; response regulator; sporulation; two-component signal transduction
MeSH headings : Amino Acid Sequence; Bacillus subtilis / chemistry; Bacillus subtilis / physiology; Bacterial Proteins / chemistry; Bacterial Proteins / drug effects; Calcium / chemistry; Calcium / pharmacology; Copper / chemistry; Copper / pharmacology; Crystallography, X-Ray; In Vitro Techniques; Magnesium / chemistry; Magnesium / pharmacology; Magnetic Resonance Spectroscopy / methods; Magnetic Resonance Spectroscopy / standards; Manganese / chemistry; Manganese / pharmacology; Models, Molecular; Molecular Sequence Data; Phosphorylation / drug effects; Protein Binding; Protein Conformation; Protein Kinases / chemistry; Protein Kinases / drug effects; Reference Standards; Signal Transduction / drug effects; Signal Transduction / physiology; Spectrometry, Mass, Electrospray Ionization / methods; Spores, Bacterial / metabolism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Evaluation of the DNA Binding Tendencies of the Transition State Regulator AbrBโ€ 

Biochemistry, 43(51), 16106โ€“16118.

By: B. Bobay n, L. Benson n, S. Naylor n, B. Feeney n, A. Clark n, M. Goshe n, M. Strauch n, R. Thompson n, J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Bacillus subtilis / metabolism; Circular Dichroism; DNA / chemistry; DNA / metabolism; Kinetics; Protein Binding / physiology; Spectrometry, Mass, Electrospray Ionization; Transcription Factors / chemistry; Transcription Factors / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018

2004 journal article

H-1, N-15, and C-13 chemical shift assignments of the Vibrio harveyi histidine phosphotransferase protein LuxU

JOURNAL OF BIOMOLECULAR NMR, 29(4), 551โ€“552.

By: D. Ulrich*, R. Thompson n, B. Basslerโ€‰*, J. Cavanagh n & J. Loriaโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Bacterial Proteins / chemistry; Carbon Isotopes; Hydrogen; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Phosphoproteins / chemistry; Vibrio / chemistry; Vibrio / enzymology
Source: Web Of Science
Added: August 6, 2018

2004 article

Sub-classification of response regulators using the surface characteristics of their receiver domains (FEBS 27785) (vol 554, pg 231, 2003)

Kojetin, D. J., Thompson, R. J., & Cavanagh, J. (2004, February 27). FEBS LETTERS, Vol. 560, pp. 227โ€“228.

By: D. Kojetin*, R. Thompson* & J. Cavanagh*

Source: Web Of Science
Added: August 6, 2018

2003 journal article

In-line desalting mass spectrometry for the study of noncovalent biological complexes

ANALYTICAL CHEMISTRY, 75(14), 3281โ€“3286.

By: J. Cavanagh n, L. Benson n, R. Thompson n & S. Naylor n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Biopolymers / chemistry; Chromatography, Gel; DNA / chemistry; Indicators and Reagents; Oligonucleotides / chemistry; Proteins / chemistry; RNA / chemistry; Spectrometry, Mass, Electrospray Ionization / methods
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Sub-classification of response regulators using the surface characteristics of their receiver domains

FEBS LETTERS, 554(3), 231โ€“236.

By: D. Kojetin n, R. Thompson n & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: OmpR sub-families; homology modeling
MeSH headings : Bacillus subtilis / chemistry; Bacillus subtilis / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / classification; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Escherichia coli / chemistry; Escherichia coli / metabolism; Genes, Regulator; Histidine Kinase; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Protein Kinases / genetics; Protein Kinases / metabolism; Protein Structure, Secondary; Protein Structure, Tertiary; Structural Homology, Protein; Trans-Activators / chemistry; Trans-Activators / classification; Trans-Activators / genetics
Source: Web Of Science
Added: August 6, 2018

2003 journal article

The effects of Ca2+ binding on the conformation of calbindin D-28K: A nuclear magnetic resonance and microelectrospray mass spectrometry study

ANALYTICAL BIOCHEMISTRY, 317(1), 59โ€“66.

By: R. Ventersโ€‰*, L. Benson*, T. Craig*, K. Paul n, D. Kordys n, R. Thompson n, S. Naylor*, R. Kumarโ€‰*, J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: calbindin D-28K; EF-hand; conformational response to calcium binding
MeSH headings : Apoproteins / chemistry; Calbindins; Calcium / metabolism; EF Hand Motifs; Escherichia coli Proteins / chemistry; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular / methods; Protein Binding; Recombinant Fusion Proteins / chemistry; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; S100 Calcium Binding Protein G / chemistry; S100 Calcium Binding Protein G / genetics; S100 Calcium Binding Protein G / metabolism; Spectrometry, Mass, Electrospray Ionization / methods
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Current approaches for the study of large proteins by NMR

JOURNAL OF MOLECULAR STRUCTURE, 602, 275โ€“292.

By: R. Ventersโ€‰*, R. Thompson n & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: NMR; large proteins; structure; methods
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Macromolecular assembly of the transition state regulator AbrB in its unbound and complexed states probed by microelectrospray ionization mass spectrometry

ANALYTICAL BIOCHEMISTRY, 306(2), 222โ€“227.

By: L. Benson*, J. Vaughn*, M. Strauch*, B. Bobay n, R. Thompson n, S. Naylor*, J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: AbrB; transition-state regulator; macromolecular assembly; mass spectrometry
MeSH headings : Bacillus subtilis; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Chromatography, Gel; DNA / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / metabolism; Escherichia coli; Macromolecular Substances; Protein Binding; Recombinant Proteins / chemistry; Recombinant Proteins / metabolism; Spectrometry, Mass, Electrospray Ionization; Transcription Factors / chemistry; Transcription Factors / metabolism
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Stoichiometries of protein - Protein/DNA binding and conformational changes for the transition-state regulator AbrB measured by pseudo cell-size exclusion chromatography-mass spectrometry

BIOCHEMISTRY, 41(25), 7859โ€“7865.

By: J. Cavanagh n, R. Thompson n, B. Bobay n, L. Benson n & S. Naylor n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Bacillus subtilis / chemistry; Bacterial Proteins / chemistry; Chromatography, Gel / instrumentation; Chromatography, Gel / methods; DNA / chemistry; DNA-Binding Proteins / chemistry; Electron Transport; Electron-Transferring Flavoproteins; Flavoproteins / chemistry; Geobacillus stearothermophilus / chemistry; Humans; Mass Spectrometry / instrumentation; Mass Spectrometry / methods; Protein Binding; Protein Conformation; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods; Transcription Factors / chemistry
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Structural and catalytic response to temperature and cosolvents of carboxylesterase EST1 from the extremely thermoacidophilic archaeon Sulfolobus solfataricus P1

BIOTECHNOLOGY AND BIOENGINEERING, 80(7), 784โ€“793.

By: A. Sehgal n, R. Tompson n, J. Cavanagh n & R. Kelly nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: DMSO; conformational flexibility; enzyme activation; thermostable
MeSH headings : Acetonitriles / chemistry; Carboxylesterase; Carboxylic Ester Hydrolases / biosynthesis; Carboxylic Ester Hydrolases / chemistry; Carboxylic Ester Hydrolases / isolation & purification; Catalysis; Dimethyl Sulfoxide / chemistry; Dimethylformamide / chemistry; Dioxanes / chemistry; Enzyme Activation; Enzyme Stability; Molecular Conformation; Quality Control; Sensitivity and Specificity; Solvents / chemistry; Species Specificity; Structure-Activity Relationship; Sulfolobus / classification; Sulfolobus / enzymology; Temperature
Sources: Web Of Science, ORCID
Added: August 6, 2018