Roberta J. Worthington Melander
Works (42)
Updated: August 2nd, 2023 21:15
2019 journal article
2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain
SCIENTIFIC REPORTS, 9.
MeSH headings : Adenosine Triphosphate / metabolism; Antitubercular Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Electron Transport / drug effects; Humans; Imidazoles / pharmacology; Microbial Sensitivity Tests; Mycobacterium tuberculosis / drug effects; Mycobacterium tuberculosis / growth & development; Oxygen Consumption / drug effects; Proton-Motive Force / drug effects; Tuberculosis / drug therapy; Tuberculosis / microbiology
doi.org (publisher)
Source: Web Of Science
Added: February 25, 2019
2019 journal article
Identification of Anti-Mycobacterial Biofilm Agents Based on the 2-Aminoimidazole Scaffold
CHEMMEDCHEM, 14(9), 927–937.
author keywords: 2-aminoimidazoles; biofilms; mycobacteria; synergy; tuberculosis
MeSH headings : Animals; Antitubercular Agents / chemistry; Antitubercular Agents / pharmacology; Biofilms / drug effects; Imidazoles / chemistry; Male; Mice; Microsomes / drug effects; Microsomes / metabolism; Mycobacterium tuberculosis / drug effects
Source: Web Of Science
Added: July 1, 2019
2019 journal article
Small Molecule Potentiation of Gram-Positive Selective Antibiotics against Acinetobacter baumannii
ACS INFECTIOUS DISEASES, 5(7), 1223–1230.
author keywords: antibiotic adjuvant; antibiotic resistance; Acinetobacter baumannii; macrolide antibiotics; glycopeptide antibiotics; lipopolysaccharide
MeSH headings : Acinetobacter Infections / drug therapy; Acinetobacter baumannii / drug effects; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacology; Bacterial Outer Membrane / drug effects; Disease Models, Animal; Drug Resistance, Multiple, Bacterial / drug effects; Drug Synergism; Glycopeptides / administration & dosage; Glycopeptides / pharmacology; Macrolides / administration & dosage; Macrolides / pharmacology; Microbial Sensitivity Tests; Moths; Small Molecule Libraries / administration & dosage; Small Molecule Libraries / pharmacology
Source: Web Of Science
Added: August 5, 2019
2019 journal article
Using 2-aminobenzimidazole derivatives to inhibit Mycobacterium smegmatis biofilm formation
MEDCHEMCOMM, 10(3), 456–459.
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Using Small-Molecule Adjuvants to Repurpose Azithromycin for Use against Pseudomonas aeruginosa
ACS INFECTIOUS DISEASES, 5(1), 141–151.
author keywords: antibiotic resistance; antibiotic adjuvant; cystic fibrosis; Pseudomonas aeruginosa
MeSH headings : Adjuvants, Pharmaceutic / chemistry; Animals; Anti-Bacterial Agents / pharmacology; Azithromycin / pharmacology; Benzimidazoles / chemistry; Benzimidazoles / pharmacology; Cystic Fibrosis / drug therapy; Cystic Fibrosis / microbiology; Disease Models, Animal; Drug Repositioning; Larva / drug effects; Larva / microbiology; Microbial Sensitivity Tests; Moths / drug effects; Moths / microbiology; Pseudomonas aeruginosa / drug effects; Respiratory Tract Infections / drug therapy
Source: Web Of Science
Added: April 20, 2020
2018 review
Narrow-spectrum antibacterial agents
[Review of ]. MEDCHEMCOMM, 9(1), 12–21.
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp.
FRONTIERS IN MOLECULAR BIOSCIENCES, 5.
author keywords: biofilms; antibiotic resistance; two-component systems; response regulators; Acinetobacter baumannii; Francisella
Source: Web Of Science
Added: January 28, 2019
2017 journal article
2-aminoimidazoles potentiate beta-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing beta-lactamase secretion and increasing cell envelope permeability
PLoS One, 12(7).
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Probing the Mechanism of LAL-32, a Gold Nanoparticle-Based Antibiotic Discovered through Small Molecule Variable Ligand Display
BIOCONJUGATE CHEMISTRY, 28(7), 1807–1810.
MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Cell Division / drug effects; Drug Discovery / methods; Drug Resistance, Bacterial; Escherichia coli / cytology; Escherichia coli / drug effects; Escherichia coli Proteins / antagonists & inhibitors; Gold; Ligands; Membrane Transport Proteins; Metal Nanoparticles / chemistry; Metal Nanoparticles / therapeutic use; Small Molecule Libraries
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria
BIOORGANIC & MEDICINAL CHEMISTRY, 25(20), 5749–5753.
MeSH headings : Acinetobacter baumannii / drug effects; Adjuvants, Pharmaceutic / chemistry; Adjuvants, Pharmaceutic / pharmacology; Colistin / pharmacology; Drug Resistance, Bacterial / drug effects; Drug Resistance, Bacterial / genetics; Escherichia coli / drug effects; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Gram-Negative Bacteria / drug effects; Klebsiella pneumoniae / drug effects; Microbial Sensitivity Tests; Polymyxins / pharmacology; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds
MOLECULAR MICROBIOLOGY, 106(2), 223–235.
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Bacterial Proteins / ultrastructure; Biofilms / drug effects; Francisella tularensis / metabolism; Gene Expression Regulation, Bacterial / genetics; Imidazoles / metabolism; Imidazoles / pharmacology; Protein Binding; Virulence / drug effects; Virulence Factors / genetics; Virulence Factors / metabolism
Source: Web Of Science
Added: August 6, 2018
2017 article
The Challenge of Overcoming Antibiotic Resistance: An Adjuvant Approach?
Melander, R. J., & Melander, C. (2017, August). ACS INFECTIOUS DISEASES, Vol. 3, pp. 559–563.
MeSH headings : Adjuvants, Pharmaceutic / pharmacology; Animals; Anti-Bacterial Agents / pharmacology; Drug Interactions; Drug Resistance, Bacterial / drug effects; Drug Resistance, Bacterial / physiology; Gram-Negative Bacteria / drug effects; Gram-Negative Bacteria / growth & development; Gram-Negative Bacteria / metabolism; Gram-Positive Bacteria / drug effects; Gram-Positive Bacteria / growth & development; Gram-Positive Bacteria / metabolism; Humans
Source: Web Of Science
Added: August 6, 2018
2017 journal article
The Discovery of 2-Aminobenzimidazoles That Sensitize Mycobacterium smegmatis and M. tuberculosis to beta-Lactam Antibiotics in a Pattern Distinct from beta-Lactamase Inhibitors
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(14), 3940–3944.
author keywords: aminobenzimidazoles; antibiotic resistance; medicinal chemistry; tuberculosis
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Benzimidazoles / chemistry; Benzimidazoles / pharmacology; Drug Discovery; Lactams / chemical synthesis; Lactams / chemistry; Lactams / pharmacology; Molecular Structure; Mycobacterium smegmatis / drug effects; Mycobacterium smegmatis / enzymology; Mycobacterium tuberculosis / drug effects; Mycobacterium tuberculosis / enzymology; beta-Lactamase Inhibitors / chemical synthesis; beta-Lactamase Inhibitors / chemistry; beta-Lactamase Inhibitors / pharmacology; beta-Lactamases / metabolism
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Marine sponge alkaloids as a source of anti-bacterial adjuvants
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 26(24), 5863–5866.
author keywords: Marine sponge; Pyrrole-imidazole alkaloid; Biofilm; Antibiotic; Adjuvant
MeSH headings : Acinetobacter baumannii / drug effects; Alkaloids / chemistry; Alkaloids / metabolism; Alkaloids / pharmacology; Animals; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacology; Dose-Response Relationship, Drug; Imidazoles / chemistry; Imidazoles / pharmacology; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Molecular Structure; Porifera; Pyrroles / chemistry; Pyrroles / pharmacology; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Potentiation of Francisella resistance to conventional antibiotics through small molecule adjuvants
MEDCHEMCOMM, 7(1), 128–131.
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Second generation modifiers of colistin resistance show enhanced activity and lower inherent toxicity
TETRAHEDRON, 72(25), 3549–3553.
author keywords: Antibiotic adjuvant; 2-Aminoimidazole; Colistin; ESKAPE pathogens; Acinetobacter baumannii; Pseudomonas aeruginosa
Source: Web Of Science
Added: August 6, 2018
2015 article
From Worms to Targeting Virulence Factors
Melander, R. J., & Melander, C. (2015, April 23). CHEMISTRY & BIOLOGY, Vol. 22, pp. 436–437.
MeSH headings : Animals; Bacterial Proteins / metabolism; Caenorhabditis elegans / microbiology; Metalloendopeptidases / metabolism; Pseudomonas aeruginosa / physiology; Virulence Factors / metabolism
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives
TETRAHEDRON LETTERS, 56(23), 3406–3409.
author keywords: Advanced glycation end-products (AGES); Bis-2-aminoimidazole; Aminoguanidine; Diabetes
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Innovative strategies for combating biofilm-based infections
Biofilm-Based Healthcare-Associated Infections, Vol Ii, 831, 69–91.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Second generation 2-aminoimidazole based advanced glycation end product inhibitors and breakers
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25(21), 4820–4823.
author keywords: Advanced glycation end-product (AGE); 2-Aminoimidazole; Akabori; Diabetes
MeSH headings : Glycation End Products, Advanced / antagonists & inhibitors; Glycation End Products, Advanced / metabolism; Imidazoles / chemical synthesis; Imidazoles / chemistry; Imidazoles / pharmacology; Molecular Structure; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2015 article
Small Steps to New Drugs for Bugs
Melander, R. J., & Selwood, D. L. (2015, January). CHEMICAL BIOLOGY & DRUG DESIGN, Vol. 85, pp. 1–3.
author keywords: antibacterial drug discovery; antibiotic resistance; novel antibacterial strategies
MeSH headings : Anti-Bacterial Agents; Drug Design; Drug Discovery / trends; Drug Resistance, Bacterial; Humans
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Controlling bacterial behavior with indole-containing natural products and derivatives
TETRAHEDRON, 70(37), 6363–6372.
author keywords: Indole; Bacterial communication; Anti-virulence; Biofilm; Antibiotic resistance
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Disruption of heterotypic community development by Porphyromonas gingivalis with small molecule inhibitors
MOLECULAR ORAL MICROBIOLOGY, 29(5), 185–193.
author keywords: biofilms; periodontal disease; porphyromonas; streptococcus; fimbriae
MeSH headings : Bacterial Adhesion / drug effects; Bacterial Proteins / antagonists & inhibitors; Bacterial Proteins / drug effects; Benzimidazoles / pharmacology; Biofilms / drug effects; Carbon-Sulfur Lyases / drug effects; Fimbriae Proteins / antagonists & inhibitors; Humans; Image Processing, Computer-Assisted / methods; Imaging, Three-Dimensional / methods; Imidazoles / pharmacology; Microbial Interactions; Microscopy, Confocal / methods; Pili, Sex / drug effects; Porphyromonas gingivalis / drug effects; Porphyromonas gingivalis / physiology; Pyrroles / pharmacology; Small Molecule Libraries; Streptococcus gordonii / physiology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Reversal of Mycobacterium tuberculosis phenotypic drug resistance by 2-aminoimidazole- based small molecules
PATHOGENS AND DISEASE, 70(3), 370–378.
author keywords: tuberculosis; drug tolerant; biofilm; 2-aminoimidazole; drug resistant; isoniazid
MeSH headings : Antitubercular Agents / chemistry; Antitubercular Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Drug Resistance, Bacterial; Humans; Imidazoles / chemistry; Imidazoles / pharmacology; Microbial Sensitivity Tests; Mycobacterium smegmatis / drug effects; Mycobacterium smegmatis / physiology; Mycobacterium tuberculosis / drug effects; Mycobacterium tuberculosis / physiology; Phenotype
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Small Molecule Downregulation of PmrAB Reverses Lipid A Modification and Breaks Colistin Resistance
ACS CHEMICAL BIOLOGY, 9(1), 122–127.
MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Colistin / chemistry; Colistin / pharmacology; Down-Regulation / drug effects; Drug Resistance, Multiple, Bacterial / drug effects; Gram-Negative Bacteria / drug effects; Gram-Negative Bacteria / genetics; Gram-Negative Bacteria / metabolism; Gram-Negative Bacterial Infections / drug therapy; Humans; Lipid A / metabolism; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Small-Molecule Suppression of beta-Lactam Resistance in Multidrug-Resistant Gram-Negative Pathogens
JOURNAL OF MEDICINAL CHEMISTRY, 57(17), 7450–7458.
MeSH headings : Animals; Cell Line; Cell Survival / drug effects; Drug Resistance, Multiple, Bacterial / drug effects; Gram-Negative Bacteria / classification; Gram-Negative Bacteria / drug effects; Hemolysis / drug effects; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Microbial Sensitivity Tests; Sheep; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; beta-Lactam Resistance / drug effects
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Thiol-modified gold nanoparticles for the inhibition of Mycobacterium smegmatis
CHEMICAL COMMUNICATIONS, 50(100), 15860–15863.
MeSH headings : Cell Line; Cell Survival / drug effects; Erythrocytes / cytology; Erythrocytes / drug effects; Gold / chemistry; Hemolysis / drug effects; Humans; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Microbial Sensitivity Tests; Mycobacterium smegmatis / drug effects; Sulfhydryl Compounds / chemistry
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Biologically inspired strategies for combating bacterial biofilms
CURRENT OPINION IN PHARMACOLOGY, 13(5), 699–706.
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bacterial Infections / drug therapy; Bacterial Infections / metabolism; Bacterial Physiological Phenomena / drug effects; Biofilms / drug effects; Humans; Quorum Sensing / drug effects; Signal Transduction / drug effects
Source: Web Of Science
Added: August 6, 2018
2013 review
Combination approaches to combat multidrug-resistant bacteria
[Review of ]. TRENDS IN BIOTECHNOLOGY, 31(3), 177–184.
author keywords: antibiotic resistance; antibiotic adjuvant
MeSH headings : Adjuvants, Pharmaceutic / therapeutic use; Anti-Bacterial Agents / therapeutic use; Bacterial Infections / drug therapy; Bacterial Infections / microbiology; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination / methods; Humans
Source: Web Of Science
Added: August 6, 2018
2013 journal article
N-Substituted 2-aminoimidazole inhibitors of MRSA biofilm formation accessed through direct 1,3-bis(tert-butoxycarbonyl)guanidine cyclization
ORGANIC & BIOMOLECULAR CHEMISTRY, 11(1), 130–137.
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Cyclization; Guanidines / chemistry; Imidazoles / chemical synthesis; Imidazoles / chemistry; Imidazoles / pharmacology; Methicillin-Resistant Staphylococcus aureus / drug effects; Molecular Structure; Structure-Activity Relationship; Triazoles / chemical synthesis; Triazoles / chemistry; Triazoles / pharmacology
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Overcoming Resistance to beta-Lactam Antibiotics
JOURNAL OF ORGANIC CHEMISTRY, 78(9), 4207–4213.
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Drug Discovery; Molecular Structure; Small Molecule Libraries / chemical synthesis; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; beta-Lactam Resistance / drug effects; beta-Lactamase Inhibitors; beta-Lactams / chemical synthesis; beta-Lactams / chemistry; beta-Lactams / pharmacology
Source: Web Of Science
Added: August 6, 2018
2013 review
Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence
[Review of ]. FUTURE MEDICINAL CHEMISTRY, 5(11), 1265–1284.
MeSH headings : Bacteria / metabolism; Bacteria / pathogenicity; Bacterial Infections / drug therapy; Bacterial Proteins / antagonists & inhibitors; Bacterial Proteins / metabolism; Biofilms / drug effects; Drug Resistance, Multiple, Bacterial / drug effects; Histidine Kinase; Humans; Protein Kinases / chemistry; Protein Kinases / metabolism; Signal Transduction / drug effects; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; Small Molecule Libraries / therapeutic use; Virulence / drug effects
Source: Web Of Science
Added: August 6, 2018
2012 journal article
2-Aminopyrimidine as a novel scaffold for biofilm modulation
Organic & Biomolecular Chemistry, 10(13), 2552–2561.
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
Deconvoluting Interspecies Bacterial Communication
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(26), 6314–6315.
author keywords: autoinducer-2; bacterial communication; 4; 5-dihydroxy-2; 3-pentanedione; NMR spectroscopy; quorum sensing
MeSH headings : Bacteria / chemistry; Pentanes / analysis; Quorum Sensing; Signal Transduction
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Exploring the Interaction Between siRNA and the SMoC Biomolecule Transporters: Implications for Small Molecule-Mediated Delivery of siRNA
CHEMICAL BIOLOGY & DRUG DESIGN, 79(1), 9–21.
author keywords: calorimetric techniques; chemical biology; molecular modeling; nanotechnology (drug discovery); RNAi and antisense techniques
MeSH headings : Cell Cycle Proteins / antagonists & inhibitors; Cell Cycle Proteins / genetics; Cell Cycle Proteins / metabolism; Cell Line; Guanidine / chemistry; Humans; Kinetics; Microscopy, Confocal; Molecular Dynamics Simulation; Protein Serine-Threonine Kinases / antagonists & inhibitors; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; RNA Interference; RNA, Small Interfering / chemistry; RNA, Small Interfering / metabolism; Small Molecule Libraries / chemical synthesis; Small Molecule Libraries / chemistry
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Foliar-Applied Small Molecule that Suppresses Biofilm Formation and Enhances Control of Copper-Resistant Xanthomonas euvesicatoria on Pepper
PLANT DISEASE, 96(11), 1638–1644.
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Potent Small-Molecule Suppression of Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(45), 11254–11257.
author keywords: 2-aminoimidazoles; adjuvants; antibiotics; antibiotic resistance; MRSA
MeSH headings : Anti-Bacterial Agents / pharmacology; Drug Resistance; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Oxacillin / pharmacology
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Small Molecule Suppression of Carbapenem Resistance in NDM-1 Producing Klebsiella pneumoniae
ACS MEDICINAL CHEMISTRY LETTERS, 3(5), 357–361.
author keywords: NDM-1; Klebsiella pneumoniae; antibiotic adjuvant; resistance suppression; 2-aminoimidazole
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Small molecule control of bacterial biofilms
Organic & Biomolecular Chemistry, 10(37), 7457–7474.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
A facile synthesis of 1,5-disubstituted-2-aminoimidazoles: Antibiotic activity of a first generation library
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21(15), 4516–4519.
author keywords: 2-Aminoimidazole; Amino aldehyde; Biofilm; Antibiotic
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Drug Resistance, Multiple, Bacterial / drug effects; Imidazoles / chemical synthesis; Imidazoles / chemistry; Imidazoles / pharmacology; Microbial Sensitivity Tests; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Evaluation of 4,5-Disubstituted-2-Aminoimidazole-Triazole Conjugates for Antibiofilm/Antibiotic Resensitization Activity Against MRSA and Acinetobacter baumannii
CHEMMEDCHEM, 6(12), 2243–2251.
author keywords: aminoimidazoles; antibiotic resensitization; biofilms; MRSA; synergism
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / physiology; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Imidazoles / chemistry; Methicillin-Resistant Staphylococcus aureus / drug effects; Methicillin-Resistant Staphylococcus aureus / physiology; Oxacillin / chemistry; Oxacillin / pharmacology; Structure-Activity Relationship; Triazoles / chemistry
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Intercepting Bacterial Indole Signaling with Flustramine Derivatives
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(50), 20160–20163.
MeSH headings : Escherichia coli / metabolism; Hydrocarbons, Brominated / metabolism; Indole Alkaloids / metabolism; Indoles / metabolism; Signal Transduction; Staphylococcus aureus / metabolism
Source: Web Of Science
Added: August 6, 2018
