Works (44)
Updated: April 6th, 2024 05:02
2024 journal article
Association between F2-isoprostanes and self-reported stressors in pregnant americans of African and European ancestry
HELIYON, 10(3).
author keywords: F2-isoprostane; Psychosocial stress; Pregnant; Depression; Anxiety
www.cell.com (publisher PDF)
Sources: Web Of Science, NC State University Libraries
Added: April 1, 2024
2023 journal article
<i>AHRR</i> Hypomethylation mediates the association between maternal smoking and metabolic profiles in children
HEPATOLOGY COMMUNICATIONS, 7(10).
TL;DR:
AHRR hypomethylation significantly mediates the association between prenatal tobacco smoke exposure and features of childhood metabolic dysfunction, despite the lack of persistent hypometHylation of AHRR into childhood.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2023
2023 journal article
Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude
CLINICAL EPIGENETICS, 15(1).
author keywords: PACE; Meta-analysis; Birth season; DNA methylation; Differentially methylated regions (DMR); Latitude
TL;DR:
Evidence is provided for associations between DNAm and season of birth that are unique for the seasons of the year (temporal effect) and latitude-dependent variations in the seasonal associations (spatial effect) and for DNAm could play a role in the molecular mechanisms underlying the effect of birth season on adult health outcomes.
(via Semantic Scholar)
Source: Web Of Science
Added: November 6, 2023
2023 journal article
Duration of exposure to epidural anesthesia at delivery, DNA methylation in umbilical cord blood and their association with offspring asthma in Non-Hispanic Black women
ENVIRONMENTAL EPIGENETICS, 9(1).
author keywords: epidural anesthesia; labor analgesia; asthma; health disparities; DNA methylation; mediation analysis
TL;DR:
It is suggested that DNA methylation in immune-related pathways contributes to the effects of the duration of exposure to epidural anesthesia on childhood asthma risk in NHB offspring.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: February 13, 2023
2023 journal article
Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States
BMC CANCER, 23(1).
author keywords: Cervical cancer; Cancer surveillance and screening; DNA methylation; Epigenomics; Epigenetics; Cancer risk; Pre-neoplasia
TL;DR:
Using prospective time-to-event data, associations between CADM1 -, DAPK1 -, PAX1 -, and RARB -related CpGs and cervical disease progression are detected and novel progression-associated CpGs are identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: December 4, 2023
2023 article
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Choudhary, P., Monasso, G. S., Karhunen, V., Ronkainen, J., Mancano, G., Howe, C. G., … Sebert, S. (2023, December 5). MOLECULAR PSYCHIATRY, Vol. 12.
TL;DR:
MEA was found to be associated with DNA methylation at 473 cytosine-phosphate-guanine sites at birth, one in childhood, and four in adolescence, directionally consistent with MEA being inversely associated with behaviours including smoking and BMI.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 16, 2024
2023 journal article
Prenatal and Childhood Smoke Exposure Associations with Cognition, Language, and Attention-Deficit/Hyperactivity Disorder
JOURNAL OF PEDIATRICS, 256, 77-+.
MeSH headings : Infant, Newborn; Female; Pregnancy; Adolescent; Humans; Child, Preschool; Attention Deficit Disorder with Hyperactivity / etiology; Cotinine; Prenatal Exposure Delayed Effects; Tobacco Smoke Pollution / adverse effects; Cognition
TL;DR:
Findings suggest childhood tobacco smoke exposure may lead to poorer attention regulation and language acquisition, complex visual processing ability, and attention problems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 12, 2023
2022 article
Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children
Moylan, C. A., Mavis, A. M., Jima, D., Maguire, R., Bashir, M., Hyun, J., … Hoyo, C. (2022, February 23). EPIGENETICS.
author keywords: DNA methylation; liver; non-alcoholic fatty liver disease; steatosis; Epigenetics; children
MeSH headings : Adolescent; Humans; Infant, Newborn; Alanine Transaminase / genetics; Alanine Transaminase / metabolism; DNA Methylation; Liver / metabolism; Non-alcoholic Fatty Liver Disease / diagnostic imaging; Non-alcoholic Fatty Liver Disease / genetics
TL;DR:
As higher LFC associates with an adverse cardiometabolic profile already in childhood, altered DNAm may identify children at high risk for NAFLD and associated metabolic dysfunction early in disease course for targeted intervention.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 7, 2022
2022 journal article
Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(18).
author keywords: differentially methylated regions; adverse offspring outcomes; infertility
MeSH headings : Child; Clomiphene; DNA Methylation; Female; Genomic Imprinting; Humans; Male; Reproductive Techniques, Assisted / adverse effects; Retrospective Studies
TL;DR:
The results suggest that the increased risk of adverse outcomes in offspring conceived through ART may be due in part to altered methylation of ICRs, and larger studies utilizing epigenome-wide interrogation are warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 3, 2022
2022 journal article
Maternal Mediterranean Diet Adherence and Its Associations with Maternal Prenatal Stressors and Child Growth
CURRENT DEVELOPMENTS IN NUTRITION, 6(11).
author keywords: Mediterranean diet; stressors; child weight; birth outcomes; maternal diet
TL;DR:
If replicated in larger studies, the data suggest that MDA provides a potent avenue by which effects of prenatal stressors on maternal and fetal outcomes can be mitigated to reduce ethnic disparities in childhood obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 20, 2023
2022 review
Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation
[Review of ]. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 789.
author keywords: DNA methylation; Sex; Children; Cord blood; EWAS
TL;DR:
A large-scale meta-analysis of the association of sex and cord blood DNA methylation at over 450,000 CpG sites in 8438 newborns from 17 cohorts participating in the Pregnancy And Childhood Epigenetics (PACE) Consortium identified additional autosomal sites with sex-specific differences inDNA methylation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 13, 2022
2022 article
Neighborhood Deprivation is Associated with Increased Risk of Prenatal Smoke Exposure
Wheeler, D. C., Boyle, J., Barsell, D. J., Maguire, R. L., Dahman, B., Murphy, S. K., … Fuemmeler, B. F. (2022, February 18). PREVENTION SCIENCE.
author keywords: Smoke exposure; Neighborhood; Socioeconomic status; Bayesian analysis
MeSH headings : Bayes Theorem; Cotinine; Ethnicity; Female; Humans; Pregnancy; Residence Characteristics; Tobacco Smoke Pollution / adverse effects; Tobacco Smoke Pollution / analysis
TL;DR:
Findings provide stronger evidence that the socio-geographic variables of educational attainment and neighborhood racial composition are important factors for smoking and secondhand smoke exposure during pregnancy and can be used to target intervention efforts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 7, 2022
2022 article
Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes
King, D. E., Sparling, A. C., Lloyd, D., Satusky, M. J., Martinez, M., Grenier, C., … Murphy, S. K. (2022, March 5). EPIGENETICS.
author keywords: Sex differences; mitochondria; DNA methylation; in utero smoke exposure
MeSH headings : Female; Humans; Male; Adenosine Triphosphate; DNA Methylation; Genes, Mitochondrial; Hormones; Reactive Oxygen Species; Tobacco Smoke Pollution; Sex Factors; Maternal Exposure
TL;DR:
The findings suggest that sex-specific DNA methylation may help establish sex differences in expression and function and thatsex-specific alterations inDNA methylation in response to exposures could contribute to sex-variable toxicological responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 21, 2022
2022 article
Sleep onset, duration, or regularity: which matters most for child adiposity outcomes?
Glasgow, T. E., Adams, E. L., Ksinan, A., Barsell, D. J., Lunsford-Avery, J., Chen, S., … Fuemmeler, B. F. (2022, May 12). INTERNATIONAL JOURNAL OF OBESITY.
MeSH headings : Adiposity; Adolescent; Adult; Body Mass Index; Child; Child, Preschool; Humans; Infant, Newborn; Obesity; Sleep; Waist Circumference
TL;DR:
Sleep duration was consistently associated with adiposity measures in children 4–13 years of age, and Pediatric sleep interventions should focus first on elongating nighttime sleep duration, and examine if this improves child adiposity outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 23, 2022
2022 article
Tobacco Retail Outlets, Neighborhood Deprivation and the Risk of Prenatal Smoke Exposure
Wheeler, D. C., Boyle, J., Barsell, D. J., Maguire, R. L., Zhang, J., Oliver, J. A., … Fuemmeler, B. F. (2022, July 19). NICOTINE & TOBACCO RESEARCH.
MeSH headings : Female; Humans; Pregnancy; Cotinine / analysis; Tobacco Smoke Pollution / adverse effects; Tobacco Smoke Pollution / analysis; Tobacco; Bayes Theorem; Pregnant Women
TL;DR:
Results suggested a significant positive association between TRO exposure and cotinine levels, after adjusting for the individual factors such as race, education, and marital status.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 26, 2022
2021 journal article
Associations between maternal obesity, gestational cytokine levels and child obesity in the NEST cohort
PEDIATRIC OBESITY, 16(7).
Contributors: n, J. House n , D. Lloyd n, H. Skinner n, T. Allen *, A. Raffi n, D. Skaar n, S. Park n
author keywords: cytokines; maternal obesity; childhood obesity
MeSH headings : Black or African American; Body Mass Index; Child; Child, Preschool; Cohort Studies; Cytokines / blood; Female; Humans; Obesity, Maternal / epidemiology; Pediatric Obesity / epidemiology; Pregnancy; White People
TL;DR:
Although maternal systemic inflammation is hypothesized to link maternal pre‐pregnancy obesity to offspring metabolic dysfunction, patient empirical data are limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 19, 2021
2021 journal article
DNA Methylation in Babies Born to Nonsmoking Mothers Exposed to Secondhand Smoke during Pregnancy: An Epigenome-Wide Association Study
ENVIRONMENTAL HEALTH PERSPECTIVES, 129(5).
MeSH headings : DNA Methylation; Epigenesis, Genetic; Epigenome; Female; Fetal Blood / chemistry; Humans; Infant, Newborn; Maternal Exposure / adverse effects; Pregnancy; Tobacco Smoke Pollution / adverse effects
TL;DR:
It is suggested that even low levels of smoke exposure during pregnancy may be sufficient to alter DNA methylation in distinct sites of mixed umbilical cord blood leukocytes in pathways that are known to be altered in cord blood from pregnant active smokers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 19, 2021
2021 journal article
Identifying the Best Questions for Rapid Screening of Secondhand Smoke Exposure Among Children
NICOTINE & TOBACCO RESEARCH, 23(7), 1217–1223.
MeSH headings : Child; Child, Preschool; Cotinine / analysis; Humans; Nutrition Surveys; Parents; Saliva / chemistry; Tobacco Smoke Pollution / adverse effects
TL;DR:
Using saliva cotinine concentration levels as a gold standard for determining SHS exposure, an analysis employing elastic net regression identified two questions that served as good classifier for distinguishing children who might be at risk for secondhand smoking exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: January 3, 2022
2021 article
Parenting Stress, Child Weight-Related Behaviors, and Child Weight Status
White, M. J., Schechter, J. C., Neely, B., Reyes, C., Maguire, R. L., Perrin, E. M., … Fuemmeler, B. F. (2021, September 24). CHILDHOOD OBESITY.
author keywords: diet; parenting; physical activity; stress
MeSH headings : Child; Child Behavior; Feeding Behavior; Humans; Infant, Newborn; Longitudinal Studies; Parenting; Pediatric Obesity / epidemiology; Sedentary Behavior; Surveys and Questionnaires
TL;DR:
Management of parenting stress may represent a reasonable adjunct to family-based behavioral interventions and Associations between parenting stress and child weight-related behaviors were not moderated by race or family structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 4, 2021
2021 journal article
Smoke-Free Home Rules and Association with Child Secondhand Smoke Exposure among Mother-Child Dyad Relationships
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(10).
author keywords: smoke-free home; smoke-free home rules; child secondhand smoke exposure; salivary cotinine; household smokers; smoking mothers
MeSH headings : Child; Female; Humans; Longitudinal Studies; Mother-Child Relations; North Carolina; Saliva / chemistry; Tobacco Smoke Pollution / analysis
TL;DR:
Smoke-free home rules are not sufficient to fully protect children from secondhand smoke exposure, especially in homes with smokers, and future research should focus on how household members who smoke can facilitate the prevention of child second hand smoke exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021
2020 journal article
Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis
TRANSLATIONAL PSYCHIATRY, 10(1).
MeSH headings : Adolescent; Attention Deficit Disorder with Hyperactivity / genetics; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Female; Humans; Infant, Newborn; Pregnancy; Prospective Studies; Schools
TL;DR:
Evidence is found that DNA methylation at birth is associated with ADHD, and future studies are needed to confirm the utility of methylation variation as biomarker and its involvement in causal pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 21, 2020
2020 journal article
Associations between attention deficit hyperactivity disorder symptoms and eating behaviors in early childhood
PEDIATRIC OBESITY, 15(7).
author keywords: ADHD; childhood; eating behaviors; latent change score; self-regulation
MeSH headings : Adolescent; Adult; Attention Deficit Disorder with Hyperactivity / psychology; Child; Child, Preschool; Cross-Sectional Studies; Feeding Behavior / psychology; Female; Humans; Hyperphagia / psychology; Male; Pediatric Obesity / etiology; Pediatric Obesity / prevention & control; Prospective Studies; Young Adult
TL;DR:
Attention‐deficit/hyperactivity disorder symptoms have been linked with eating behaviors and obesity adolescence and young adulthood, but little is known about whether these associations occur during early childhood and few studies have examined these associations prospectively.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 23, 2020
2020 journal article
DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
GENOME MEDICINE, 12(1).
author keywords: Body mass index; Childhood obesity; DNA methylation; Epigenetics
MeSH headings : Adolescent; Body Mass Index; Child; Child, Preschool; CpG Islands; Cross-Sectional Studies; DNA Methylation; Epigenesis, Genetic; Epigenome; Female; Fetal Blood; Humans; Male; Obesity / genetics; Parturition; Pediatric Obesity / genetics; Pregnancy
TL;DR:
The strength of the associations of DNA methylation at the 187 CpGs previously identified to be associated with adult BMI, increased with advancing age across childhood and adolescence in the authors' analyses, compatible with the hypothesis thatDNA methylation differences are mostly a consequence rather than a cause of obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 21, 2020
2020 journal article
The association between neuraxial anesthesia and the development of childhood asthma - a secondary analysis of the newborn epigenetics study cohort
CURRENT MEDICAL RESEARCH AND OPINION, 36(6), 1025–1032.
author keywords: Anesthesia; opioid analgesics; asthma; children; sex-specific
MeSH headings : Adult; Anesthesia, Epidural / adverse effects; Anesthesia, Obstetrical / adverse effects; Asthma / etiology; Cesarean Section / adverse effects; Child; Child, Preschool; Epigenesis, Genetic; Female; Humans; Infant, Newborn; Logistic Models; Male; Pregnancy; Retrospective Studies
TL;DR:
The data suggest that peripartum exposure to neuraxial anesthesia may reduce the risk of childhood asthma primarily in males.
(via Semantic Scholar)
Source: Web Of Science
Added: June 22, 2020
2019 journal article
Associations between imprinted gene differentially methylated regions, appetitive traits and body mass index in children
PEDIATRIC OBESITY, 14(2).
author keywords: Appetite; body mass index; imprinted genes; children
MeSH headings : Appetite / genetics; Birth Weight / genetics; Body Mass Index; Calcium-Binding Proteins; Child; Child, Preschool; DNA Methylation / genetics; Epigenesis, Genetic / genetics; Feeding Behavior / physiology; Female; Fetal Blood / metabolism; Genomic Imprinting / genetics; Humans; Infant; Infant, Newborn; Insulin-Like Growth Factor II / genetics; Intercellular Signaling Peptides and Proteins / genetics; Male; Membrane Proteins / genetics; Phenotype; Pregnancy; Sex Factors; Surveys and Questionnaires
TL;DR:
This study highlights the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 4, 2019
2019 journal article
Elevated metabolites of acetaminophen in cord blood of children with obesity
PEDIATRIC OBESITY, 14(1).
Contributors: P. Sorrow n, n, S. Murphy *, S. Belcher n & C. Hoyo n
author keywords: Acetaminophen; children; metabolomics; obesity
MeSH headings : Acetaminophen / blood; Acetaminophen / metabolism; Case-Control Studies; Child, Preschool; Fatty Acids / blood; Female; Fetal Blood / metabolism; Humans; Male; Metabolomics / methods; Pediatric Obesity / blood; Pregnancy
TL;DR:
High‐throughput metabolomics has been used cross‐sectionally to evaluate differential metabolic profiles associated with human obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 7, 2019
2019 journal article
Epigenome-wide meta-analysis of DNA methylation and childhood asthma
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 143(6), 2062–2074.
author keywords: Epigenetics; methylation; asthma; childhood; newborn; drug development
MeSH headings : Asthma / genetics; Child; CpG Islands / genetics; Cross-Sectional Studies; DNA Methylation; ERG1 Potassium Channel / genetics; Epigenesis, Genetic; Epigenome / genetics; Genome-Wide Association Study; Humans; Infant, Newborn; Interleukin-5 Receptor alpha Subunit / genetics
TL;DR:
Novel loci differentially methylated in newborns represent potential biomarkers of risk of asthma by school age, and Asthma-related differential methylation in blood in children was substantially replicated in eosinophils and respiratory epithelium.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 24, 2019
2019 journal article
Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study
EPIGENETICS, 14(4), 325–340.
author keywords: DNA methylation; epigenome-wide association study; maternal obesity; offspring body mass index; offspring blood pressure; cardiometabolic health; ALSPAC; NEST
MeSH headings : Adult; Blood Pressure; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / genetics; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Genome-Wide Association Study; Humans; Infant, Newborn / blood; Infant, Newborn / growth & development; Male; Membrane Transport Proteins / genetics; Metabolic Syndrome / epidemiology; Metabolic Syndrome / genetics; Obesity / epidemiology; Obesity / genetics
TL;DR:
Findings suggest sex-specific effects at CpG sites of the TAPBP gene were associated with BMI z-score and systolic BP percentile in female and syStolic and diastolicBP percentile in male offspring, which, if causal, may explain observed sex- specific effects of maternal obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 29, 2019
2019 journal article
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
NATURE COMMUNICATIONS, 10.
MeSH headings : Adolescent; Adult; Birth Weight / genetics; Body Mass Index; Child; CpG Islands; DNA / genetics; DNA / metabolism; DNA Methylation; Epigenesis, Genetic; Female; Fetal Development / genetics; Fetus; Folic Acid / blood; Genome, Human; Genome-Wide Association Study; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / etiology; Prenatal Exposure Delayed Effects / genetics; Prenatal Exposure Delayed Effects / physiopathology; Smoking / adverse effects; Smoking / blood; Smoking / genetics
TL;DR:
A meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium finds that DNA methylation in neonatal blood is associated with birthweight at 914 sites, with a difference in birthweight ranging from −183 to 178 grams per 10% increase in methylation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 13, 2019
2019 journal article
Pre-Pregnancy Weight and Symptoms of Attention Deficit Hyperactivity Disorder and Executive Functioning Behaviors in Preschool Children
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 16(4).
author keywords: pregnancy; gestational weight gain; maternal obesity; child development; ADHD
MeSH headings : Adult; Attention Deficit Disorder with Hyperactivity / etiology; Attention Deficit Disorder with Hyperactivity / psychology; Body Mass Index; Child; Child, Preschool; Executive Function; Female; Follow-Up Studies; Gestational Weight Gain; Humans; Male; North Carolina; Pregnancy; Prenatal Exposure Delayed Effects / etiology; Prenatal Exposure Delayed Effects / psychology; Regression Analysis; Risk Factors
TL;DR:
Pre-pregnancy BMI at levels ≥35 was positively associated with higher ADHD symptoms and worse executive self-regulation behaviors (inhibitory control and attention), and a link between maternal weight and child neurodevelopment is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2019 journal article
Snacking frequency and dietary intake in toddlers and preschool children
APPETITE, 142.
author keywords: Dietary intake; Diet quality; Preschooler; Snacking; Toddler
MeSH headings : Black People / statistics & numerical data; Child; Child, Preschool; Diet / ethnology; Diet / statistics & numerical data; Diet Surveys; Dietary Carbohydrates / administration & dosage; Dietary Fats / administration & dosage; Dietary Proteins / administration & dosage; Energy Intake / ethnology; Epigenesis, Genetic; Female; Hispanic or Latino / statistics & numerical data; Humans; Infant; Male; Snacks / ethnology; White People / statistics & numerical data
TL;DR:
Snacking frequency was positively and significantly associated with total daily energy intake in both 12-to-24-month-olds and 2- to-6-year-olds as indicated by regression coefficient estimates of snacking frequency.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: November 25, 2019
2018 journal article
Cohort profile: Pregnancy and childhood epigenetics (PACE) consortium
International Journal of Epidemiology, 47(1), 22-.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
DNA methylation of imprinted gene control regions in the regression of low-grade cervical lesions
INTERNATIONAL JOURNAL OF CANCER, 143(3), 552–560.
author keywords: methylation; imprinted genes; cervical cancer; neoplasia; epigenetics; HPV
MeSH headings : Adult; Aged; Biopsy; CpG Islands; DNA Methylation; Disease Progression; Epigenesis, Genetic; Female; Genomic Imprinting; Humans; Middle Aged; Neoplasm Grading; Neoplasm Staging; Regulatory Sequences, Nucleic Acid; Uterine Cervical Neoplasms / epidemiology; Uterine Cervical Neoplasms / etiology; Uterine Cervical Neoplasms / genetics; Uterine Cervical Neoplasms / pathology; Young Adult
TL;DR:
Altered methylation of imprinted IGF2AS and PEG10 DMRs may play a role in the natural history of CIN1, and further research on imprinted gene DMR methylation is warranted to determine its efficacy as a biomarker for cervical cancer screening.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Effects of cadmium exposure on DNA methylation at imprinting control regions and genome-wide in mothers and newborn children
Environmental Health Perspectives, 126(3).
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
Periconceptional maternal mediterranean diet is associated with favorable offspring behaviors and altered CpG methylation of imprinted genes
Frontiers in Cell and Developmental Biology, 6(SEP), 107.
Contributors: J. House n , M. Mendez*, n, S. Gonzalez-Nahm *, Z. Huang *, J. Daniels *, S. Murphy *, B. Fuemmeler *, F. Wright n, C. Hoyo n
TL;DR:
In this ethnically diverse cohort, maternal adherence to a Mediterranean diet in early pregnancy was associated with favorable neurobehavioral outcomes in early childhood and with sex-dependent methylation differences of MEG3, IGF2, and SGCE/PEG10 DMRs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: January 21, 2019
2017 journal article
Disparities in cervical cancer incidence and mortality: Can epigenetics contribute to eliminating disparities?
Cancer Disparities, 133, 129–156.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Epigenetic regulation of AXL and risk of childhood asthma symptoms
Clinical Epigenetics, 9.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
Human Molecular Genetics, 26(20), 4067–4085.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight
BMC Public Health, 17.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Maternal inflammatory diet and adverse pregnancy outcomes: Circulating cytokines and genomic imprinting as potential regulators?
EPIGENETICS, 12(8), 688–697.
author keywords: Birthweight; cytokines; diet; DNA methylation; epidemiology; imprinted lgenes; inflammation
MeSH headings : Adolescent; Adult; Cytokines / blood; DNA Methylation; Diet; Female; Genomic Imprinting; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Pregnancy Outcome / epidemiology; Pregnancy Outcome / genetics
TL;DR:
This work replicates work by others on the association between maternal inflammatory diet and adverse pregnancy outcomes and provides the first empirical evidence supporting the inverse association between circulating cytokine concentrations and offspring methylation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Association between Prepregnancy Body Mass Index and Gestational Weight Gain with Size, Tempo, and Velocity of Infant Growth: Analysis of the Newborn Epigenetic Study Cohort
CHILDHOOD OBESITY, 12(3), 210–218.
MeSH headings : Adult; Body Mass Index; Child Development; Child, Preschool; Epigenomics; Female; Humans; Hypertension, Pregnancy-Induced / epidemiology; Infant; Infant, Newborn; Male; Mothers; Obesity / epidemiology; Parity; Pregnancy; Pregnancy Complications / epidemiology; Risk Factors; Smoking / epidemiology; Southeastern United States / epidemiology; Time Factors; Weight Gain
TL;DR:
The findings contribute new data on the associations between gestational weight gain and aspects of early growth using the SITAR method, and support a growing consensus in the literature that both prepregnancy BMI and gestations relate independently to risk for greater postnatal weight growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Geographic clustering of elevated blood heavy metal levels in pregnant women
BMC PUBLIC HEALTH, 15(1).
author keywords: Cadmium; Lead; Mercury; Arsenic; Spatial analysis
MeSH headings : Adult; Arsenic / blood; Cadmium / blood; Female; Humans; Lead / blood; Maternal Exposure / statistics & numerical data; Mercury / blood; Metals, Heavy / blood; Pregnancy; Pregnancy Complications / blood; Pregnancy Complications / epidemiology; Prenatal Care / statistics & numerical data; Prenatal Exposure Delayed Effects / prevention & control; Rural Population / statistics & numerical data; United States / epidemiology; Urban Population / statistics & numerical data; Young Adult
TL;DR:
Elevated blood concentrations of Cd and Pb are spatially clustered in this urban environment compared to the surrounding areas and cluster membership was associated with lower education levels and higher pre-pregnancy BMI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
IL-10, IL-15, IL-17, and GMCSF levels in cervical cancer tissue of Tanzanian women infected with HPV16/18 vs. non-HPV16/18 genotypes
Infectious Agents and Cancer, 10.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Maternal cadmium, iron and zinc levels, DNA methylation and birth weight
BMC Pharmacology & Toxicology, 16.
Source: NC State University Libraries
Added: August 6, 2018
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