Ryan Deruiter

College of Engineering

Works (5)

Updated: July 5th, 2023 14:44

2022 journal article

An Analysis of Sonothrombolysis and Cavitation for Retracted and Unretracted Clots Using Microbubbles Versus Low-Boiling-Point Nanodroplets

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 69(2), 711–719.

By: J. Kim*, K. Bautista*, R. Deruiter*, L. Goel*, X. Jiang n, Z. Xu *, P. Dayton*

author keywords: Ultrasonic imaging; Acoustics; Medical treatment; Frequency control; Coagulation; Transducers; Surface treatment; Cavitation; microbubble (MB); nanodroplet (ND); retracted clot; sonothrombolysis; thrombosis
MeSH headings : Aged; Blood Coagulation; Humans; Microbubbles; Thrombosis / diagnostic imaging; Thrombosis / therapy; Ultrasonic Therapy / methods
TL;DR: It is concluded that ND-mediated sonothrombolysis outperforms MB-mediated therapy regardless of clot retraction, and this advantage of ND- mediated cavitation is emphasized for retracted clots. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 14, 2022

2022 journal article

In situ ultrasound imaging of shear shock waves in the porcine brain

JOURNAL OF BIOMECHANICS, 134.

By: S. Chandrasekaran n, F. Santibanez n, B. Tripathi*, R. DeRuiter n, R. Bruegge n & G. Pinton n

author keywords: Ultrasound imaging; RF tracking; Motion tracking; Shear waves; Shock waves
MeSH headings : Animals; Brain / diagnostic imaging; Brain Injuries, Traumatic; Elasticity Imaging Techniques / methods; Head; Motion; Phantoms, Imaging; Swine; Ultrasonography / methods
TL;DR: The experimental velocity, acceleration, and strain-rate waveforms in brain for the monochromatic impact are shown to be in excellent agreement with theoretical predictions from a custom higher-order finite volume method hence demonstrating the capabilities to measure rapid brain motion despite strong acoustical reverberations from the porcine skull. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 16, 2022

2020 journal article

A COMPARISON OF SONOTHROMBOLYSIS IN AGED CLOTS BETWEEN LOWBOILING-POINT PHASE-CHANGE NANODROPLETS AND MICROBUBBLES OF THE SAME COMPOSITION

ULTRASOUND IN MEDICINE AND BIOLOGY, 46(11), 3059–3068.

By: J. Kim n, R. DeRuiter n, L. Goel n, Z. Xu *, X. Jiang n & P. Dayton n

author keywords: Sonothrombolysis; Nanodroplets; Microbubbles; Cavitation; Clot
MeSH headings : Animals; Cattle; Mechanical Thrombolysis / methods; Microbubbles; Nanostructures; Thrombosis / therapy; Time Factors; Transition Temperature; Ultrasonic Therapy
TL;DR: Enhanced cavitation erosion of blood clots exposed to low-boiling-point (-2°C) perfluorocarbon phase-change nanodroplets and pulsed ultrasound, as well as microbubbles with the same formulation under the same conditions are presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 12, 2020

2020 journal article

Quantitative sub-resolution blood velocity estimation using ultrasound localization microscopy ex-vivo and in-vivo

BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, 6(3).

By: D. Espindola  n, R. DeRuiter n, F. Santibanez n, P. Dayton n & G. Pinton n

author keywords: ultrasound imaging; super-resolution; blood flow
MeSH headings : Algorithms; Animals; Blood Flow Velocity; Blood Vessels / diagnostic imaging; Calibration; Contrast Media; Equipment Design; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Mice; Microbubbles; Microscopy / methods; Microvessels / diagnostic imaging; Phantoms, Imaging; Reproducibility of Results; Signal Processing, Computer-Assisted; Transducers; Ultrasonography / instrumentation; Ultrasonography / methods
TL;DR: It is shown that the parabolic flow profiles within these micro-vessels are resolvable and velocity measurements are in excellent agreement with theoretical predictions within the considered range of flow rates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 18, 2020

2020 journal article

Transient acoustic vaporization signatures unique to low boiling point phase change contrast agents enable super-resolution ultrasound imaging without spatiotemporal filtering

AIP ADVANCES, 10(10).

By: R. DeRuiter n, E. Markley n, J. Rojas n, G. Pinton n & P. Dayton n

TL;DR: The proposed PCCA SR technique does not require the use of user-dependent and flow-dependent spatio-temporal filtering via singular-value decomposition, rather, matched filters selected by Fourier-domain analysis are able to identify and localize PCCAs activations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: November 24, 2020

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