Ryan Deruiter

College of Engineering

Works (7)

Updated: August 16th, 2025 21:45

2025 article

Improving Imaging Field of View of 3-D Transcranial Rat Brain Super-Resolution With Robotic Registered Compounding and Nonrigid Deformation Correction

DeRuiter, R. M., Jones, R. M., Belgharbi, H., Sode, M., Lee, H. R., Santibanez, F., … Pinton, G. F. (2025, May 29). IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control.

By: R. DeRuiter n, R. Jones n, H. Belgharbi n, M. Sode n, H. Lee n, F. Santibanez  n, P. Dayton n, G. Pinton n

author keywords: Imaging; Rats; Three-dimensional displays; Ultrasonic imaging; Acoustics; Skull; Superresolution; Frequency control; Probes; In vivo; Contrast-enhanced ultrasound; microvascular imaging; super-resolution; transcranial imaging; ultrasound localization microscopy (ULM)
MeSH headings : Animals; Rats; Brain / diagnostic imaging; Imaging, Three-Dimensional / methods; Robotics / methods; Rats, Sprague-Dawley; Phantoms, Imaging
topics (OpenAlex): Medical Imaging Techniques and Applications; Advanced MRI Techniques and Applications; Brain Tumor Detection and Classification
Source: Web Of Science
Added: July 17, 2025

2024 article

Non-invasive 4D transcranial functional ultrasound and ultrasound localization microscopy for multimodal imaging of neurovascular response

Jones, R. M., DeRuiter, R. M., Lee, H. R., Munot, S., Belgharbi, H., Santibanez, F., … Pinton, G. F. (2024, December 4). Scientific Reports.

By: R. Jones  n, R. DeRuiter n, H. Lee  n, S. Munot*, H. Belgharbi n, F. Santibanez  n, O. Favorov n, P. Dayton n, G. Pinton*

author keywords: 4D imaging; Functional ultrasound; Multimodal imaging; Non-invasive transcranial imaging; Ultrasound Localization Microscopy
MeSH headings : Multimodal Imaging / methods; Humans; Cerebrovascular Circulation / physiology; Brain / diagnostic imaging; Brain / blood supply; Brain / physiology; Male; Ultrasonography / methods; Ultrasonography, Doppler, Transcranial / methods; Microscopy / methods; Neurovascular Coupling / physiology; Female; Animals
topics (OpenAlex): Photoacoustic and Ultrasonic Imaging; Ultrasound Imaging and Elastography; Ultrasound and Hyperthermia Applications
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Source: Web Of Science
Added: January 13, 2025

2022 article

In situ ultrasound imaging of shear shock waves in the porcine brain

Chandrasekaran, S., Santibanez, F., Tripathi, B. B., DeRuiter, R., Bruegge, R. V., & Pinton, G. (2022, January 4). Journal of Biomechanics.

By: S. Chandrasekaran n, F. Santibanez  n, B. Tripathi*, R. DeRuiter n, R. Bruegge & G. Pinton n

author keywords: Ultrasound imaging; RF tracking; Motion tracking; Shear waves; Shock waves
MeSH headings : Animals; Brain / diagnostic imaging; Brain Injuries, Traumatic; Elasticity Imaging Techniques / methods; Head; Motion; Phantoms, Imaging; Swine; Ultrasonography / methods
topics (OpenAlex): Automotive and Human Injury Biomechanics; Traumatic Brain Injury Research; Traumatic Brain Injury and Neurovascular Disturbances
TL;DR: The experimental velocity, acceleration, and strain-rate waveforms in brain for the monochromatic impact are shown to be in excellent agreement with theoretical predictions from a custom higher-order finite volume method hence demonstrating the capabilities to measure rapid brain motion despite strong acoustical reverberations from the porcine skull. (via Semantic Scholar)
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Source: Web Of Science
Added: May 16, 2022

2021 journal article

An Analysis of Sonothrombolysis and Cavitation for Retracted and Unretracted Clots Using Microbubbles Versus Low-Boiling-Point Nanodroplets

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(2), 711–719.

By: J. Kim*, K. Bautista*, R. Deruiter*, L. Goel*, X. Jiang n , Z. Xu *, P. Dayton*

author keywords: Ultrasonic imaging; Acoustics; Medical treatment; Frequency control; Coagulation; Transducers; Surface treatment; Cavitation; microbubble (MB); nanodroplet (ND); retracted clot; sonothrombolysis; thrombosis
MeSH headings : Aged; Blood Coagulation; Humans; Microbubbles; Thrombosis / diagnostic imaging; Thrombosis / therapy; Ultrasonic Therapy / methods
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound and Cavitation Phenomena; Photoacoustic and Ultrasonic Imaging
TL;DR: It is concluded that ND-mediated sonothrombolysis outperforms MB-mediated therapy regardless of clot retraction, and this advantage of ND- mediated cavitation is emphasized for retracted clots. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: February 14, 2022

2020 article

A Comparison of Sonothrombolysis in Aged Clots between Low-Boiling-Point Phase-Change Nanodroplets and Microbubbles of the Same Composition

Kim, J., DeRuiter, R. M., Goel, L., Xu, Z., Jiang, X., & Dayton, P. A. (2020, August 13). Ultrasound in Medicine & Biology, Vol. 46, pp. 3059–3068.

By: J. Kim n, R. DeRuiter n, L. Goel n, Z. Xu *, X. Jiang n  & P. Dayton n

author keywords: Sonothrombolysis; Nanodroplets; Microbubbles; Cavitation; Clot
MeSH headings : Animals; Cattle; Mechanical Thrombolysis / methods; Microbubbles; Nanostructures; Thrombosis / therapy; Time Factors; Transition Temperature; Ultrasonic Therapy
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound and Cavitation Phenomena; Photoacoustic and Ultrasonic Imaging
TL;DR: Enhanced cavitation erosion of blood clots exposed to low-boiling-point (-2°C) perfluorocarbon phase-change nanodroplets and pulsed ultrasound, as well as microbubbles with the same formulation under the same conditions are presented. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 12, 2020

2020 article

Quantitative sub-resolution blood velocity estimation using ultrasound localization microscopy ex-vivo and in-vivo

Espíndola, D., DeRuiter, R. M., Santibanez, F., Dayton, P. A., & Pinton, G. (2020, March 12). Biomedical Physics & Engineering Express.

By: D. Espíndola  n, R. DeRuiter n, F. Santibanez  n, P. Dayton n & G. Pinton n

author keywords: ultrasound imaging; super-resolution; blood flow
MeSH headings : Algorithms; Animals; Blood Flow Velocity; Blood Vessels / diagnostic imaging; Calibration; Contrast Media; Equipment Design; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Mice; Microbubbles; Microscopy / methods; Microvessels / diagnostic imaging; Phantoms, Imaging; Reproducibility of Results; Signal Processing, Computer-Assisted; Transducers; Ultrasonography / instrumentation; Ultrasonography / methods
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound Imaging and Elastography; Photoacoustic and Ultrasonic Imaging
TL;DR: It is shown that the parabolic flow profiles within these micro-vessels are resolvable and velocity measurements are in excellent agreement with theoretical predictions within the considered range of flow rates. (via Semantic Scholar)
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Source: Web Of Science
Added: May 18, 2020

2020 article

Transient acoustic vaporization signatures unique to low boiling point phase change contrast agents enable super-resolution ultrasound imaging without spatiotemporal filtering

DeRuiter, R. M., Markley, E. N., Rojas, J. D., Pinton, G. F., & Dayton, P. A. (2020, October 1). AIP Advances.

By: R. DeRuiter n, E. Markley n, J. Rojas n, G. Pinton n & P. Dayton n

topics (OpenAlex): Ultrasound and Hyperthermia Applications; Photoacoustic and Ultrasonic Imaging; Ultrasound Imaging and Elastography
TL;DR: The proposed PCCA SR technique does not require the use of user-dependent and flow-dependent spatio-temporal filtering via singular-value decomposition, rather, matched filters selected by Fourier-domain analysis are able to identify and localize PCCAs activations. (via Semantic Scholar)
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Source: Web Of Science
Added: November 24, 2020

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