@article{furgurson_loschin_butoto_abugu_gillespie_brown_ferraro_speicher_stokes_budnick_et al._2023, title={Seizing the policy moment in crop biotech regulation: an interdisciplinary response to the Executive Order on biotechnology}, volume={11}, ISSN={["2296-4185"]}, DOI={10.3389/fbioe.2023.1241537}, abstractNote={North Carolina State University Forestry and Environmental Resources, Raleigh, NC, United States, North Carolina State University Genetic Engineering and Society Center, Raleigh, NC, United States, North Carolina State University Applied Ecology, Raleigh, NC, United States, North Carolina State University Crop and Soil Sciences, Raleigh, NC, United States, North Carolina State University Horticultural Science, Raleigh, NC, United States, North Carolina State University Entomology and Plant Pathology, Raleigh, NC, United States, North Carolina State University Food, Bioprocessing and Nutrition Sciences, Raleigh, NC, United States, North Carolina State University Agricultural and Resource Economics, Raleigh, NC, United States, North Carolina State University Communication, Rhetoric, and Digital Media, Raleigh, NC, United States, North Carolina State University Biochemistry, Raleigh, NC, United States, North Carolina State University Plant Biology, Raleigh, NC, United States, North Carolina State University Anthropology, Raleigh, NC, United States}, journal={FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY}, author={Furgurson, Jill and Loschin, Nick and Butoto, Eric and Abugu, Modesta and Gillespie, Christopher J. and Brown, Rebekah and Ferraro, Greg and Speicher, Nolan and Stokes, Ruthie and Budnick, Asa and et al.}, year={2023}, month={Aug} }
 @article{barnes_rodriguez-zapata_juarez-nunez_gates_janzen_kur_wang_jensen_estevez-palmas_crow_et al._2022, title={An adaptive teosinte mexicana introgression modulates phosphatidylcholine levels and is associated with maize flowering time}, volume={119}, ISSN={["1091-6490"]}, url={http://dx.doi.org/10.1073/pnas.2100036119}, DOI={10.1073/pnas.2100036119}, abstractNote={Native Americans domesticated maize (Zea maysssp.mays) from lowland teosinteparviglumis(Zea maysssp.parviglumis)in the warm Mexican southwest and brought it to the highlands of Mexico and South America where it was exposed to lower temperatures that imposed strong selection on flowering time. Phospholipids are important metabolites in plant responses to low-temperature and phosphorus availability and have been suggested to influence flowering time. Here, we combined linkage mapping with genome scans to identifyHigh PhosphatidylCholine 1(HPC1), a gene that encodes a phospholipase A1 enzyme, as a major driver of phospholipid variation in highland maize. Common garden experiments demonstrated strong genotype-by-environment interactions associated with variation atHPC1,with the highlandHPC1allele leading to higher fitness in highlands, possibly by hastening flowering. The highland maizeHPC1variant resulted in impaired function of the encoded protein due to a polymorphism in a highly conserved sequence. A meta-analysis across HPC1 orthologs indicated a strong association between the identity of the amino acid at this position and optimal growth in prokaryotes. Mutagenesis ofHPC1via genome editing validated its role in regulating phospholipid metabolism. Finally, we showed that the highlandHPC1allele entered cultivated maize by introgression from the wild highland teosinteZea maysssp.mexicanaand has been maintained in maize breeding lines from the Northern United States, Canada, and Europe. Thus,HPC1introgressed from teosintemexicanaunderlies a large metabolic QTL that modulates phosphatidylcholine levels and has an adaptive effect at least in part via induction of early flowering time.}, number={27}, journal={PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA}, publisher={Proceedings of the National Academy of Sciences}, author={Barnes, Allison C. and Rodriguez-Zapata, Fausto and Juarez-Nunez, Karla A. and Gates, Daniel J. and Janzen, Garrett M. and Kur, Andi and Wang, Li and Jensen, Sarah E. and Estevez-Palmas, Juan M. and Crow, Taylor M. and et al.}, year={2022}, month={Jul} }